Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL by Sarka Pavlova, Jitka Malcikova, Lenka Radova, Silvia Bonfiglio, Jack B. Cowland, Christian Brieghel, Mette K. Andersen, Maria Karypidou, Bella Biderman, Michael Doubek, Gregory Lazarian, Inmaculada Rapado, Matthijs Vynck, Naomi A. Porret, Martin Andres, Dina Rosenberg, Dvora Sahar, Carolina Martínez‐Laperche, Ismael Buño, Andrew Hindley, David Donaldson, Julio B. Sánchez, José A. García‐Marco, Alicia Serrano‐Alcalá, Blanca Ferrer‐Lores, Concepción Fernández‐Rodriguez, Beatriz Bellosillo, Stephan Stilgenbauer, Eugen Tausch, Hero Nikdin, Fiona Quinn, Emer Atkinson, Lisette van deCorput, Cafer Yildiz, Cristina Bilbao‐Sieyro, Yanira Florido, Christian Thiede, Caroline Schuster, Anastazja Stoj, Sylwia Czekalska, Anastasia Chatzidimitriou, Stamatia Laidou, Audrey Bidet, Charles Dussiau, Friedel Nollet, Giovanna Piras, Maria Monne, Svetlana Smirnova, Eugene Nikitin, Ivan Sloma, Alexis Claudel, Laetitia Largeaud, Loïc Ysebaert, Peter J. M. Valk, Amy Christian, Renata Walewska, David Oscier, Marta Sebastião, Maria Gomes daSilva, Piero Galieni, Mario Angelini, Davide Rossi, Valeria Spina, Sónia Matos, Vânia Martins, Tomasz Stokłosa, Monika Pepek, Panagiotis Baliakas, Rafa Andreu, Irene Luna, Tiina Kahre, Ülle Murumets, Tereza Pikousova, Terezia Kurucova, Sophie Laird, Daniel Ward, Miguel Alcoceba, Ana Balanzategui, Lydia Scarfo, Francesca Gandini, Ettore Zapparoli, Adoración Blanco, Pau Abrisqueta, Ana E. Rodríguez‐Vicente, Rocío Benito, Clotilde Bravetti, Frédéric Davi, Paula Gameiro, Joaquin Martinez‐Lopez, Bárbara Tazón‐Vega, Fanny Baran‐Marszak, Zadie Davis, Mark Catherwood, Andrey Sudarikov, Richard Rosenquist, Carsten U. Niemann, Kostas Stamatopoulos, Paolo Ghia, Sarka Pospisilova

“…Targeted therapy in ≥2 line diminished the difference in OS between patients with low‐VAF TP53 variants and wt‐TP53 patients, while patients with high‐VAF TP53 variants had inferior OS compared to wild type‐TP53 cases. …”
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Assessing and predicting the value of ecosystem services in Sanya City, Hainan Island, China by Peihong Song, Qiu Yang, Wenyin Wu, Tianyan Su, Yamin Jiang, Jingli Lu, Zhongyi Sun, Jie Zhang, Rui Yu, Peng Wang, Lan Wu, Huai Yang, Wenjie Liu

“…This study found that Gross Domestic Product (GDP), Normalized Difference Vegetation Index (NDVI), and population had significant impacts on ESV, while forest and water areas exhibited notable individual impact. …”
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Echocardiographic and biomarker characteristics in diabetes, coronary artery disease or both: insights from HOMAGE trial by Luca Monzo, Masatake Kobayashi, João Pedro Ferreira, Zohra Lamiral, Christian Delles, Andrew L. Clark, Frank Edelmann, Arantxa González, Stephane Heymans, Pierpaolo Pellicori, Johannes Petutschnigg, Job A. J. Verdonschot, Patrick Rossignol, John G. F. Cleland, Faiez Zannad, Nicolas Girerd, on behalf of the HOMAGE “Heart Omics in AGEing” Trial Committees and Investigators

“…At follow-up, the effect of spironolactone on echocardiographic variables and circulating biomarkers was not significantly different across DM/CAD phenotypes (all p-interaction > 0.05), except for a more pronounced reduction in GDF-15 in the DM+/CAD + group at the 1-month visit (p-interaction = 0.03). …”
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Perfusion‐Based Relative Cerebral Blood Volume Is Associated With Functional Dependence in Large‐Vessel Occlusion Ischemic Stroke by Dhairya A. Lakhani, Aneri B. Balar, Manisha Koneru, Sijin Wen, Burak Berksu Ozkara, Justin Caplan, Adam A. Dmytriw, Richard Wang, Hanzhang Lu, Meisam Hoseinyazdi, Mehreen Nabi, Ishan Mazumdar, Andrew Cho, Kevin Chen, Sadra Sepehri, Nathan Hyson, Risheng Xu, Victor Urrutia, Licia P. Luna, Argye Hillis, Jeremy J. Heit, Greg W. Albers, Ansaar T. Rai, Tobias Faizy, Max Wintermark, Kambiz Nael, Vivek S. Yedavalli

“…The majority of the patients (n=161) in our cohort had M1 occlusion. All the rCBV thresholds were significantly higher in patients with poor 90‐day functional outcomes and were independently associated with the outcome. …”
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Effect of the time factor on the hydraulic activity of mechanically activated saponin-containing powder by Marina V. Morozova, Maria A. Frolova

“…Further, using the algorithm for calculating the activity parameters of powders, according to potentiometry data, the maximum amount of absorbed calcium hydroxide (∆ССaO ) was determined as the difference between the . Results and Discussion. The resulting mechanically activated saponite-containing powder had a specific surface area of 196 m2/kg (10 min), 644 m2/kg (30 min), 1209 m2/kg (60 min), 1428 m2/kg (90 min) at different milling times. …”
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Exploring the Effects of Internal and External Factors on the Early Growth of Anchovy (Engraulis japonicus) in the Yellow Sea Based on Otolith Microstructure by Wenwen WANG, Yongjun TIAN, Lijun LIU, Zhuo YIN, Bingqing CHEN, Wenchao ZHANG, Zhenjiang YE

“…However, their relative importance varied by month, indicating different regulatory mechanisms for anchovies hatching in the same area during different times of the year. …”
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Feasibility of extracting specimens from the site of preventive ileostomy and its impact on stoma retraction of laparoscopic low anterior resection for rectal cancer by Bai Junge, Wang Zhexue, Yang Ming, Ma Xiaolong, Liu Zheng, Chen Haipeng

“…There was no significant difference in the ileostomy closure rate between the two groups (χ2＝1.204，P＝0.272). …”
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How to Implement Digital Clinical Consultations in UK Maternity Care: the ARM@DA Realist Review by Catrin Evans, Georgia Clancy, Kerry Evans, Andrew Booth, Benash Nazmeen, Candice Sunney, Mark Clowes, Nia Wyn Jones, Stephen Timmons, Helen Spiby

“…A conceptual framework was produced that illustrates the inter-relationship between key contexts in maternity care through which different interactions activate mechanisms to produce outcomes of interest. …”
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Influence of Harvesting Stage on Phytochemical Composition, Antioxidant, and Antidiabetic Activity of Immature <i>Ceratonia siliqua</i> L. Pulp from Béni Mellal-Khénifra Region, Mo... by Salah Laaraj, Hanane Choubbane, Amal Elrherabi, Aziz Tikent, Ayoub Farihi, Meriem Laaroussi, Mohamed Bouhrim, Abdelaaty A. Shahat, Younes Noutfia, Rashed N. Herqash, Fatiha Chigr, Souad Salmaoui, Kaoutar Elfazazi

“…The three locations showed peak values for total polyphenol content (TPC), total flavonoid content (TFC), and total condensed tannin (TCT) at the M2 stage. AW had the highest concentrations of TPC (3819 ± 226.4 mg GAE/100 g FM), TFC (1034 ± 57.08 mg QE/100 g FM), and TCT (1472 ± 28.46 mg CE/100 g FM). …”
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The association between traumatic temporomandibular joint bony ankylosis and depressive disorder in growing rats by Tiange Deng, Yang Xue, Yiming Wang, Xiang Guo, Zhen Ma, Hongzhi Zhou, Zaiyong Yang, Zhengwu Peng, Xiangxiang Hu, Ning Li, Kaijin Hu, Lei Wang

“…Abstract Background The psychological symptoms of temporomandibular joint (TMJ) ankylosis were similar to that of depressive disorder, but there were no relevant evidences to confirm that the humans or animals with TMJ ankylosis had depressive disorder. The aim of this study was to investigate the association between TMJ ankylosis and depressive disorder in the rat model. …”
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The role of glutathione S-transferase mu 2 in mitigating fatty acid–induced hepatic inflammation in dairy cows by Jinxia Li, Chenchen Zhao, Dandan Qi, Fanrong Kong, Menglin Liu, Jie Gao, Enzhu Li, Wenwen Gao, Xiliang Du, Yuxiang Song, Xinwei Li, Haihua Feng, Lin Lei

“…Compared with healthy cows, cows with severe fatty liver had higher plasma concentrations of NEFA, BHB, haptoglobin (HP), plasma amyloid A (SAA), and lower plasma concentration of glucose. …”
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Left ventricular flow kinetics and myocardial deformation following acute infarction: Additional predictive value of cardiac magnetic resonance four-dimensional flow for left ventr... by Christel H. Kamani, May Lwin, Ioannis Botis, Mehak Asad, Noor Sharrack, Hadar Schapira, Arka Das, Peter P. Swoboda, Sven Plein, Rob J. Van der Geest, Erica Dall’Armellina

“…At 3M post-STEMI, LVremod patients had significantly reduced LVEF, increased IS, abnormal FT-strain, systolic KEiEDV, DF, and RV compared to LVnon-remod patients. …”
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Escala Barcelona para la apraxia bucofonatoria: instrumento de evaluación cuantitativo by N. Montagut, S. Borrego-Écija, J. Herrero, A. Lladó, M. Balasa, E. Muñoz, F. Valldeoriola, R. Sánchez-Valle

“…Results: Patients showed a significantly higher score compared to controls. The group nfvPPA had the highest mean score on the scale (429 seconds ± 278). …”
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Microplastic and Copper Exposure Effects on Intestinal Gene Expression in Eriocheir sinensis: A Transcriptomics-Based Investigation by Jian XU, Guangpeng FENG, Yunzhi YAN, Jinhui CHEN, Jianhui WU, Zuchang YANG

“…In contrast, exposure to Cu2+ alone and co-exposure to MPs had comparatively smaller impacts on this pathway. …”
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蛋黄脂质粉末油脂制备工艺优化及性质研究Optimization of preparation process and properties of egg yolk lipids powdered oil by 蔡芸丹1，2，饶胜其3，顾璐萍1，2，常翠华1，2，李俊华1，2，杨严俊1，2，苏宇杰1，2 CAI Yundan1,2，RAO Shengqi3，GU Luping1,2，CHANG Cuihua1,2， LI Junhua1,2, YANG Yanjun1,2, SU Yujie1,2

“…Three kinds of egg yolk lipids powdered oil were prepared under the optimal preparation conditions, in which the powdered oil of egg yolk lipids extracted by supercritical CO2 extraction had lower moisture content, good fluidity, intact spherical structure of the particles, high content of polyunsaturated fatty acids and higher storage stability than that of the ethanol extraction method. …”
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Study of Planting Pattern and Herbicide Effects on Weed Population and Chickpea (Cicer arietinum L.) Grain Yield by Hossein Najafi, Soheyla Pourheydar Ghafarbi, Gholamreza Gahramanian, Ajang Jahedi

“…Field results indicated that all herbicides had the same effect on the weed dry weight and chickpea grain yield at both planting row distance. …”
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Relationship between macrophage phenotype and kidney survival in patients with lupus nephritis by Ozcan Uzun, Cihan Heybeli, Fatma Sema Anar Kutlu, Evrim Atmaca, Filiz Yıldırım, Caner Cavdar, Sulen Sarioglu

“…Results: Among the 21 patients, 52% had class III or IV LN. During the median follow-up of 88 months, 5 (23.8%) patients experienced progression. …”
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Measurement report: Aircraft observations of aerosol and microphysical quantities of stratocumulus in autumn over Guangxi Province, China – daylight variation, vertical distributio... by S. Liu, H. Wang, D. Zhao, D. Zhao, W. Zhou, Y. Du, Z. Zhang, P. Cheng, T. Zhao, Y. Ke, Z. Wu, M. Huang

“…<span class="inline-formula"><i>E</i>_d</span> and <span class="inline-formula"><i>N</i>_a</span> remain negatively correlated in different liquid water content ranges, and the FIE (aerosol first indirect effect) ranged from <span class="inline-formula">−</span>0.07 to <span class="inline-formula">−</span>0.58.…”
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Saturated Hydraulic Conductivity of Nine Soils According to Water Quality, Soil Texture, and Clay Mineralogy by Clarissa Buarque Vieira, Gabriel Henrique Maximo Clarindo Silva, Brivaldo Gomes de Almeida, Luiz Guilherme Medeiros Pessoa, Fernando José Freire, Valdomiro Severino de Souza Junior, Hidelblandi Farias de Melo, Luara Gabriella Gomes de Lima, Rodrigo Francisco do Nascimento Paiva, Jorge Freire da Silva Ferreira, Maria Betânia Galvão dos Santos Freire

“…The K_sat may differ from soil to soil according to the sodium adsorption ratio (SAR), water electrical conductivity (EC_w), soil texture, and clay mineralogical assemblage. …”
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Effects of Hypoxic Stress on Tissue Structure and Gut Bacterial Community of Exopalaemon carinicauda by Xinlei ZHOU, Qingyang LI, Jiawei ZHU, Shumin XIE, Mintao WANG, Ting YANG, Chaofan XING, Huan GAO, Qingqi ZHANG, Panpan WANG

“…Rhodobacteraceae bacteria had a relative high abundance in the gut of healthy E. carinicauda and their amounts were significantly reduced after hypoxic stress. …”
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