Weighted Gene Correlation Network Analysis Reveals Key Regulatory Genes Influencing Selenium Enrichment and Yield with Exogenous Selenite in Tartary Buckwheat by Xueling Ye, Linsen Mei, Zhen Gan, Zhiqiang Wang, Wenjun Sun, Yu Fan, Changying Liu, Qi Wu, Yan Wan, Xiaoyong Wu, Dabing Xiang

“…To determine the optimal Se treatment concentration and fully understand its effects on Tartary buckwheat, sodium selenite (Na₂SeO₃) in different concentrations was sprayed onto leaves of Tartary buckwheat at the initial flowering stage. …”
Get full text

Association between neutrophil-lymphocyte ratio and female breast cancer: an observational study from NHANES 2001-2018 with external validation by Juan Xiong, Juan Xiong, Juan Xiong, Deju Zhang, Deju Zhang, Jing Wu, Jing Wu, Peili Yang, Donghai Shi, Donghai Shi, Xiaolan Zhou, Ying Yuan, Ying Yuan, Chuntao Quan, Ni Xie, Ni Xie

“…External validation in Chinese clinical participants supported the generalizability of these findings across different populations.…”
Get full text

A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs by Marit A. K. Hetland, Mia A. Winkler, Håkon P. Kaspersen, Fredrik Håkonsholm, Ragna-Johanne Bakksjø, Eva Bernhoff, Jose F. Delgado-Blas, Sylvain Brisse, Annapaula Correia, Aasmund Fostervold, Margaret M. C. Lam, Bjørn-Tore Lunestad, Nachiket P. Marathe, Niclas Raffelsberger, Ørjan Samuelsen, Marianne Sunde, Arnfinn Sundsfjord, Anne Margrete Urdahl, Ryan R. Wick, Iren H. Löhr, Kathryn E. Holt

“…Nearly 5% of human infection isolates had close relatives (≤22 substitutions) amongst animal and marine isolates, despite temporally and geographically distant sampling of these sources. …”
Get full text

Incidence and Prevention of Vaginal Cuff Dehiscence After Laparoscopic and Robotic Hysterectomy in Benign Conditions: An Updated Systematic Review and Meta-Analysis by Pier Carlo Zorzato, Riccardo Vizza, Simone Garzon, Mariachiara Bosco, Anna Festi, Alberta Ricci, Irene Porcari, Giacomo Corrado, Rosa Maria Laterza, Stefano Uccella

“…Robotic-assisted hysterectomy had a pooled VCD rate of 1.7%, compared to laparoscopic hysterectomy at 0.7%. …”
Get full text

Investigating autonomic dysfunction in post-COVID-19 syndrome from skin to brain: A case-control study using EMG-SSR and fNIRS by Jia-Yin Ma, Jia-Jia Wu, Yi Zhu, Mou-Xiong Zheng, Xu-Yun Hua, Jian-Guang Xu

“…To characterize the correlation between SSR and significantly different topological metrics of fNIRS network, Spearman correlation analysis was performed. …”
Get full text

Comparison of New‐Onset Peripheral Artery Disease in Patients With Type 2 Diabetes Exposed to Sodium–Glucose Cotransporter‐2 Inhibitors, Dipeptidyl Peptidase‐4 Inhibitors, or Gluca... by Oscar Hou‐In Chou, Zhiyao Luo, Cheuk To Skylar Chung, Jeffrey Chan, Huixian Li, Ishan Lakhani, Sharen Lee, Dawnie Ho Hei Lau, Qingpeng Zhang, Tong Liu, Wing Tak Wong, Bernard Man Yung Cheung, Gregory Y. H. Lip, Fung Ping Leung, Gary Tse, Jiandong Zhou

“…After matching, 186 and 256 patients had PAD in the SGLT2I and DPP4I groups, respectively, over a median follow‐up of 5.6 years. …”
Get full text

Exploring Effects of Age at the Onset of Myopia on Multiple Diseases Using Electronic Health Records by Xiayin Zhang, PhD, Shan Wang, MD, Yu Huang, PhD, Yanjie Xie, PhD, Ishith Seth, MD, Gabriella Bulloch, MD, Chunran Lai, MD, Yijun Hu, PhD, Xianwen Shang, PhD, Mingguang He, PhD, Zhuoting Zhu, PhD, Honghua Yu, PhD

“…Participants were eligible if they had available genetic information during recruitment between March 13, 2006, and October 1, 2010. …”
Get full text

Real-world impact of COVID-19 vaccination, household exposure, and circulating SARS-CoV-2 variants on infection risk and symptom presentation in a U.S./Mexico border community by Ariel Cohen, Breanna Reyes, Maria Linda Burola, Angel Lomeli, Arleth A. Escoto, Linda Salgin, Borsika A. Rabin, Borsika A. Rabin, Nicole A. Stadnick, Nicole A. Stadnick, Nicole A. Stadnick, Ilya Zaslavsky, Robert Tukey, Louise C. Laurent, Marva Seifert

“…Our findings also underscore the necessity for enhancing workplace safety protocols, addressing language-specific considerations, and being cognizant of differing symptom presentation by variant.…”
Get full text

Growth-promoting hormonal alterations in pregnant women living with HIV receiving dolutegravir-based antiretroviral treatment are associated with lower infant 1-year weight z-score... by Kathleen M. Powis, Kathleen M. Powis, Kathleen M. Powis, Jennifer Jao, Jennifer Jao, Jennifer Jao, Justine Legbedze, Caroline Dunk, Keolebogile N. Mmasa, Samuel W. Kgole, Gosego Masasa, Terence Mohammed, Joseph Makhema, Sikhulile Moyo, Mitchell E. Geffner, Elaine J. Abrams, Lena Serghides, Lena Serghides

“…Similar models were fit to assess effect modification by HIV status on the relationship between each maternal hormone and infant anthropometrics at birth and 1-year of age.ResultsMaternal plasma specimens were available from 114 women (46 with HIV). Women with HIV had lower mean log bioavailable estradiol (β: −0.22, p = 0.031), cortisol (β: −0.22, p = 0.001), and IGF-1 (β: −0.81, p = 0.007), but higher GH1 (β: 0.91, p = 0.007) than women without HIV. …”
Get full text

Associations of HLA-G 3’UTR polymorphisms and increased HLA-G expression with gastric cancer susceptibility and prognosis by Ines Zemni, Daria Bortolotti, Sabrine Dhouioui, Sana Baroudi, Malek Ferjani, Inès Nasri, Yosr Zenzri, Md Ataur Rahman, Abdel Halim Harrath, Roberta Rizzo, Nadia Boujelbene, Inès Zidi

“…Compared with HD, GC patients had higher soluble HLA-G, shed HLA-G1 and HLA-G5 levels (Mann-Whitney: p = 0.001, p = 0.001 and p = 0.643, respectively). …”
Get full text

Structure and Function Analyses of the Thioredoxin 2 and Thioredoxin Reductase Gene in Pacific White Shrimp (<i>Litopenaeus vannamei</i>) by Tong Xu, Pei-Hua Zheng, Ke-Er Luan, Xiu-Xia Zhang, Jun-Tao Li, Ze-Long Zhang, Wei-Yan Hou, Li-Min Zhang, Yao-Peng Lu, Jian-An Xian

“…After LPS injection, the <i>LvTrx2</i> and <i>LvTrxR</i> transcripts in hepatopancreas and gill had different upregulated levels. These findings suggest that <i>LvTrx2</i> and <i>LvTrxR</i> play pivotal roles in enhancing stress resistance and bolstering antibacterial defense mechanisms in <i>L. vannamei</i>. …”
Get full text

Effects of combining yeast products with antimicrobials in grain adaptation diets for feedlot Nellore bulls on performance, behavior, and metabolome by Richard Vaquero Ribeiro, Welder Angelo Baldassini, Welder Angelo Baldassini, Nara Regina Brandão Cônsolo, José Breno da Silva Moreira, Rodrigo de Nazaré Santos Torres, Jean Lucas Carvalho Galvão, Luis Artur Loyola Chardulo, Luis Artur Loyola Chardulo, Rogério Abdallah Curi, Rogério Abdallah Curi, Gabriel Henrique Ribeiro, Gabriel Henrique Ribeiro, Luiz Alberto Colnago, Otávio Rodrigues Machado Neto, Otávio Rodrigues Machado Neto

“…During the finishing period, bulls fed NLY had a lower (P = 0.04) DMI as a percentage of body weight than bulls receiving MVY. …”
Get full text

Propensity score–weighted analysis of chemotherapy after PD-1 inhibitors versus chemotherapy alone in patients with non–small cell lung cancer (WJOG10217L) by Nobuyuki Yamamoto, Ryoji Kato, Hidetoshi Hayashi, Yasutaka Chiba, Eriko Miyawaki, Junichi Shimizu, Tomohiro Ozaki, Daichi Fujimoto, Ryo Toyozawa, Atsushi Nakamura, Toshiyuki Kozuki, Kentaro Tanaka, Shunsuke Teraoka, Kazuhiro Usui, Kazumi Nishino, Osamu Hataji, Keiichi Ota, Noriyuki Ebi, Sho Saeki, Yuki Akazawa, Motoyasu Okuno, Kazuhiko Nakagawa

“…We therefore applied propensity score analysis to investigate the efficacy of chemotherapy after PD-1 inhibitor treatment (CAP) compared with chemotherapy alone.Methods We conducted a retrospective observational cohort study for patients treated at 47 institutions across Japan between April 1, 2014 and July 31, 2017. Eligible patients had advanced or recurrent NSCLC who have undergone chemotherapy. …”
Get full text

Multimorbidity clusters and their associations with health-related quality of life in two UK cohorts by Lewis Steell, Stefanie J. Krauth, Sayem Ahmed, Grace O. Dibben, Emma McIntosh, Peter Hanlon, Jim Lewsey, Barbara I. Nicholl, David A. McAllister, Susan M. Smith, Rachael Evans, Zahira Ahmed, Sarah Dean, Colin Greaves, Shaun Barber, Patrick Doherty, Nikki Gardiner, Tracy Ibbotson, Kate Jolly, Paula Ormandy, Sharon A. Simpson, Rod S. Taylor, Sally J. Singh, Frances S. Mair, Bhautesh D. Jani, the PERFORM research team

“…In UKHLS, clusters of cardiometabolic disease had the lowest HRQoL. Notably, negative associations between MLTC clusters containing painful conditions and HRQoL remained significant even after adjusting for number of LTCs. …”
Get full text

Effects of aerobic or resistance exercise during neoadjuvant chemotherapy on tumor response and therapy completion in women with breast cancer: The randomized controlled BENEFIT tr... by Martina E. Schmidt, Siri Goldschmidt, Charlotte Kreutz, Jana Müller, Andreas Schneeweiss, Anne M. May, Friederike Rosenberger, Joachim Wiskemann, Karen Steindorf

“…Results: Overall, there was no significant difference in post-intervention tumor size between RT or AT and WCG. …”
Get full text

Comparative analysis of echocardiographic and electrocardiographic data of survivors and deceased patients with COVID-19 (sub-analysis of the international register “Dynamics analy... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, Y. N. Belenkov, A. O. Konradi, Y. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, A. R. Vaisberg, N. Y. Grigorieva, B. B. Ogurlieva, I. V. Fomin, I. A. Frolova, O. Yu. Badina, O. E. Vilkova, N. V. Zarechnova, N. A. Kamardina, E. V. Koroleva, K. V. Mazalov, D. V. Soloveva

“…In addition, deceased patients had longer QTc interval (440 [416; 450] vs 400 [380; 430] ms, p&lt;0,001).Conclusion. …”
Get full text

Open repair of type IV thoracoabdominal aortic aneurysms: a real-world experience in the endovascular era. by Marta Romão Rodrigues, Tiago Magalhães, Ryan Gouveia e Melo, Luis Silvestre, Ruy Fernandes e Fernandes, Emanuel Silva, Pedro Amorim, Augusto Ministro, Carlos Martins, Luis Mendes Pedro

“…Infectious complications occurred in 29%, mainly lower respiratory infections (17%). Two patients (8%) had cardiac complications (acute myocardial infarction and non-ischemic cardiogenic shock). …”
Get full text

Machine learning and multi-omics analysis reveal key regulators of proneural–mesenchymal transition in glioblastoma by Can Xu, Jin Yang, Huan Xiong, Xiaoteng Cui, Yuhao Zhang, Mingjun Gao, Lei He, Qiuyue Fang, Changxi Han, Wei Liu, Yangyang Wang, Jin Zhang, Ying Yuan, Zhaomu Zeng, Ruxiang Xu

“…Four immune evaluation algorithms and TIDE analysis showed that the C1 cluster had high levels of immune cell infiltration and immune molecule scores. …”
Get full text

Climate-Smart Drip Irrigation with Fertilizer Coupling Strategies to Improve Tomato Yield, Quality, Resources Use Efficiency and Mitigate Greenhouse Gases Emissions by Xinchao Ma, Yanchao Yang, Zhanming Tan, Yunxia Cheng, Tingting Wang, Liyu Yang, Tao He, Shuang Liang

“…The D3N3 treatment improved (28.2%) the net global warming potential (GWP), but reduced GHGI, due to improved (18.4%) tomato yield. The D3N3 treatment had significantly greater irrigation water productivity (IWP) (42.8%), total soluble sugar (TSS) (32.9%), vitamin C content (VC) (39.2%), soluble sugar content (SSC) (44.2%), lycopene content (41.3%) and nitrogen use efficiency (NUE) (52.4%), as compared to D1N1 treatment. …”
Get full text

Prevalence, correlates of psychological distress and mental health challenges among college and university students during the COVID-19 lockdowns in South Africa by Sibusiso Sifunda, Ronel Sewpaul, Tholang Mokhele, Musawenkosi Mabaso, Inbarani Naidoo, Natisha Dukhi, Saahier Parker, Adlai Davids, Adlai Davids, Nompumelelo Zungu, Nompumelelo Zungu, Olive Shisana, Olive Shisana, Ruth Makgalemane, Semone Thakoordeen-Reddy, Priscilla Reddy

“…About one third (66.7%) of the youth reported that they had mild to severe distress (MSD). The prevalence of psychological distress among the youth differed significantly by age group, gender, risk perception of contracting COVID-19, year of study, institution and community type (p &lt; 0.05). …”
Get full text