Dissolved oxygen and nitrates gradient influence marine microbial complexity and stability in Beibu Gulf by Qing He, Qingxiang Chen, Xinyi Qin, Shengyao Zhou, Rajapakshalage Thashikala Nethmini, Gonglingxia Jiang, Qinghua Hou, Xiaolei Li, Laizhen Huang, Ke Dong, Lingling Xie, Nan Li

“…Deterministic processes significantly structured bacterial communities. The BL had the most complex network, while the ML showed the highest stability. …”
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Comprehensive Molecular Analysis of Disease-Related Genes as First-Tier Test for Early Diagnosis, Classification, and Management of Patients Affected by Nonsyndromic Ichthyosis by Tiziana Fioretti, Fabrizio Martora, Ilaria De Maggio, Adelaide Ambrosio, Carmelo Piscopo, Sabrina Vallone, Felice Amato, Diego Passaro, Fabio Acquaviva, Francesca Gaudiello, Daniela Di Girolamo, Valeria Maiolo, Federica Zarrilli, Speranza Esposito, Giuseppina Vitiello, Luigi Auricchio, Elena Sammarco, Daniele De Brasi, Roberta Petillo, Antonella Gambale, Fabio Cattaneo, Rosario Ammendola, Paola Nappa, Gabriella Esposito

“…Among the 24 different disease-causing alleles we identified, 8 carried novel variants, including a synonymous <i>TGM1</i> variant that resulted in a splicing defect. …”
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From antioxidant to muscle enhancer: Resveratrol's role in grass carp (Ctenopharyngodon idella) nutrition by Xi-Dong Xie, Lin Feng, Wei-Dan Jiang, Pei Wu, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Rui-Nan Zhang, Xiao-Qiu Zhou

“…Our findings demonstrated that resveratrol supplementation had no adverse effects on the growth performance of adult grass carp. …”
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Rapid screening of 420 pesticide residues in fruits and vegetables using ultra high performance liquid chromatography combined with quadrupole-time of flight mass spectrometry by Junmei Ma, Sufang Fan, Liqiong Yang, Liangna He, Hongwen Zhai, Xiaowei Ren, Qiang Li, Yan Zhang

“…The results showed that 420 pesticides had good linearity in the range of 0.1–100 μg/L, and the correlation coeffificients (R2) was greater than 0.990. …”
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Change in depressive symptom scores to assess the risk of new-onset dual sensory impairment in middle-aged and older adults: a nationwide cohort study by Jiang Wang, Jiang Wang, Lanzhi Duan, Lanzhi Duan, Rui Zeng, Fayi Xie, Zhigang Wu, Zhigang Wu, Yanhong Luo, Yanhong Luo, Xiaoming Zhang, Wei Li, Wei Li, Wei Li, Dongmei Ye, Ke Zhu, Tenghui Fan, Aizhang Zhu, Aizhang Zhu, Lihuan Chen, Wan Zhu, Yueyue Zhao, Hongmei Hu, Hongmei Hu, Yi Xiao

“…We also explored whether the association of CES-D-10 scores with DSI varies across different subgroups.ResultsOne thousand and sixty one out of 3,237 participants had a new-onset DSI during 3 years. …”
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Pericatheter Leak Associated With Earlier Peritoneal Dialysis Initiation Does Not Influence Long-Term Outcomes by George Tsihlis, Kieren Pirabhahar, Frederika Sciberras, MaryAnn Nicdao, Laraine Aw, Alvie Agoo, Vincent Lee, Jennifer Li, Lukas Kairaitis, Kamal Sud, Jan Swinnen, Katrina Chau

“…Results: A total of 297 patients (70% male, mean age 58.7 years) were included, with 130 (43.8%) patients undertaking ESPD. Most patients had laparoscopically inserted catheters (65.3%) and 65 patients (22.0%) received prior hemodialysis. …”
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Exploring patient preferences for intraocular lenses selection in age-related cataract: a discrete choice experiment study by Qiaolin Zhu, Qiaolin Zhu, Qiaolin Zhu, Qianqian Sun, Qianqian Sun, Qianqian Sun, Yujia Huo, Yujia Huo, Yujia Huo, Xiaoling Yang, Xiaoling Yang, Xiaoling Yang, Hehe Huang, Hehe Huang, Hehe Huang, Shanshan Qian, Shanshan Qian, Shanshan Qian, Wenjing Lin, Wentao Yan, Wentao Yan, Wentao Yan

“…Participants made choices based on different combinations of these attributes, and the data were analyzed using multinomial logit models (MNL) and latent class analysis (LCA) to identify preference heterogeneity.ResultsA total of 200 cataract patients (mean age 66.2 years, 58.5% female) participated in the study. …”
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De Novo or inherited: gonosomal mosaicism in hereditary angioedema due to C1 inhibitor deficiency by Laura Batlle-Masó, Laura Batlle-Masó, Laura Batlle-Masó, Janire Perurena-Prieto, Janire Perurena-Prieto, Janire Perurena-Prieto, Laura Viñas-Giménez, Laura Viñas-Giménez, Laura Viñas-Giménez, Aina Aguiló-Cucurull, Aina Aguiló-Cucurull, Paula Fernández-Álvarez, Johana Gil-Serrano, Johana Gil-Serrano, Johana Gil-Serrano, Mar Guilarte, Mar Guilarte, Mar Guilarte, Roger Colobran, Roger Colobran, Roger Colobran, Roger Colobran

“…Here, we report a patient with apparently sporadic HAE-C1-INH. The patient had compatible clinical symptoms and a markedly low C1-INH function, and the parents showed normal values of C4 and normal C1-INH function. …”
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An Artificial Intelligence Generated Automated Algorithm to Measure Total Kidney Volume in ADPKD by Jonathan Taylor, Richard Thomas, Peter Metherall, Marieke van Gastel, Emilie Cornec-Le Gall, Anna Caroli, Monica Furlano, Nathalie Demoulin, Olivier Devuyst, Jean Winterbottom, Roser Torra, Norberto Perico, Yannick Le Meur, Sebastian Schoenherr, Lukas Forer, Ron T. Gansevoort, Roslyn J. Simms, Albert C.M. Ong

“…The majority of CYSTic patients had PKD1 mutations (79%) and typical disease (Mayo Imaging class 1, 86%). …”
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Risk prediction in diffuse large B-cell lymphoma improves when combining baseline PET features with interim PET response by Jakoba J. Eertink, Martijn W. Heymans, Sanne E. Wiegers, Annelies L. Bes, Ulrich Duhrsen, Andreas Huttmann, Lars Kurch, Sally F. Barrington, George N. Mikhaeel, Pieternella J. Lugtenburg, Luca Ceriani, Emanuele Zucca, Tamas Gyorke, Sandor Czibor, Gerben J.C. Zwezerijnen, Ronald Boellaard, Josee M. Zijlstra, Christine Hanoun

“…All patients within the PETRA database with newly diagnosed DLBCL treated with R-CHOP, who had available clinical data, baseline PET and iPET scans were included. …”
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The dilemma of X-linked agammaglobulinemia carriers by Federica Pulvirenti, MD, PhD, Cinzia Milito, MD, PhD, Francesco Cinetto, MD, PhD, Giulia Garzi, MD, Germano Sardella, MD, Giuseppe Spadaro, MD, Francesca Lippi, MD, Valentina Guarnieri, MD, Bianca Laura Cinicola, MD, Maria Carrabba, MD, PhD, Daniele Guadagnolo, MD, Giovanna Fabio, MD, Baldassarre Martire, MD, Caterina Cancrini, MD, PhD, Giulia Lanzoni, MD, Andrea Finocchi, MD, PhD, Gigliola Di Matteo, MD, PhD, Eva Pompilii, MD, Simona Ferrari, BD, PhD, Isabella Quinti, MD, PhD

“…Three carriers refused prenatal testing and had 6 live births, including 3 XLA-affected sons. …”
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Antiplatelet Therapy in Myocardial Bridge: Insights From the RIALTO Registry by Renzo Laborante, Giuseppe Ciliberti, Gaetano Rizzo, Francesco Canonico, Donato Antonio Paglianiti, Fabio Casamassima, Attilio Restivo, Domenico Cicchella, Francesco Burzotta, Carlo Trani, Cristina Aurigemma, Mattia Galli, Rocco Vergallo, Italo Porto, Gianluca Anastasia, Giuseppe Massimo Sangiorgi, Gianluca Massaro, Marta Cocco, Simone Biscaglia, Gianluca Campo, Daniele Andreini, Antonio Maria Leone, Filippo Crea, Giuseppe Patti, Domenico D'Amario

“…At a median follow‐up of 1661 days, patients with MB receiving single APT had a higher rate of net adverse clinical events (adjusted hazard ratio [aHR], 6.2; P=0.03), mainly driven by a higher rate of minor bleeding events (aHR, 10.58; P=0.02), with no difference regarding ischemic events. …”
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Estimating Leaf Nitrogen Accumulation Considering Vertical Heterogeneity Using Multiangular Unmanned Aerial Vehicle Remote Sensing in Wheat by Yuanyuan Pan, Jingyu Li, Jiayi Zhang, Jiaoyang He, Zhihao Zhang, Xia Yao, Tao Cheng, Yan Zhu, Weixing Cao, Yongchao Tian

“…Results showed that LNASum models had markedly higher accuracy compared to LNAnon. …”
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Maintenance of flower color dimorphism in Ophiorrhiza japonica (Rubiaceae): responses to fluctuating temperatures in a dolomite Karst region by Xiao-Yue Wang, Xiao-Yue Wang, Han-Qing Tang, Han-Qing Tang, Yun-Jing Liu, Yun-Jing Liu, Meng-Da Xiang, Meng-Da Xiang, Ren-Xiu Yao, Ren-Xiu Yao, Bai-Zhu Li, Yu Li, Yu Li, Yin Yi, Yin Yi, Zhi-Rui Wen, Zhi-Rui Wen, Ming Tang, Ming Tang, Xiao-Xin Tang, Xiao-Xin Tang

“…However, the ratio of pink to white morph differed significantly between spring and winter. The temperature of pink morph was higher than that of white morph at temperatures ranging from 0-24°C, while white morph had higher temperatures than pink morph at -4°C. …”
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Reirradiation based on diffusion-weighted magnetic resonance imaging-guided dose- painting for locally advanced recurrent nasopharyngeal carcinoma: a phase 2 randomized controlled... by Chao Tan, Yuyi Li, Xiaoyu Chen, Weichang Zhu, Cuihong Jiang, Lili He, Shuai Xiao, Changgen Fan, Xu Ye, Qi Zhao, Wenqiong Wu, Yanxian Li, Yanfang Qiu, Kailin Chen, Shulu Hu, Feng Liu, Hui Wang

“…Grade 3–4 toxicities between the two groups showed no significant difference. Multivariate analysis revealed that DWI-guided DP-IMRT was an independent prognostic factor for PFS and LRFS. …”
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Frailty, Pitavastatin, and Major Adverse Cardiovascular Events Among People With HIV by Kristine M. Erlandson, MD, MS, Ariela R. Orkaby, MD, Triin Umbleja, MSc, Heather J. Ribaudo, PhD, Todd T. Brown, MD, PhD, Markella V. Zanni, MD, Marissa R. Diggs, AB, Sarah M. Chu, MSN, Kathleen V. Fitch, MSN, Carl J. Fichtenbaum, MD, Carlos Malvestutto, MD, MPH, Judith A. Aberg, MD, Gerald S. Bloomfield, MD, MPH, Judith S. Currier, MD, Karen T. Tashima, MD, Marcus Vinícius Guimarães de Lacerda, MD, PhD, Sonya L. Heath, MD, Michael T. Lu, MD, MPH, Alan Landay, PhD, George A. Kuchel, MD, Pamela S. Douglas, MD, Steven K. Grinspoon, MD

“…Results: Of 7769 REPRIEVE participants, 7,740 (>99%) had sufficient data to calculate frailty index. …”
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Impact of vaccination on kinetics of neutralizing antibodies against SARS-CoV-2 by serum live neutralization test based on a prospective cohort by Liguo Zhu, Naiying Mao, Changhua Yi, Aidibai Simayi, Jialu Feng, Yi Feng, Min He, Songning Ding, Yin Wang, Yan Wang, Mingwei Wei, Jie Hong, Chuchu Li, Hua Tian, Lu Zhou, Jiefu Peng, Shihan Zhang, Ci Song, Hui Jin, Fengcai Zhu, Wenbo Xu, Jun Zhao, Changjun Bao

“…Compared to those with higher levels of NAbs, those with lower levels of NAbs had no difference in viral clearance duration time (P>0.05), did exhibit higher viral load at the beginning of infection/maximum viral load of infection. …”
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Real-World efficiency of pembrolizumab in metastatic melanoma patients following adjuvant anti-PD1 treatment by Michael Weichenthal, Inge Marie Svane, Johanna Mangana, Ulrike Leiter, Friedegund Meier, Christina Ruhlmann, Dimitrios Ziogas, Reinhard Dummer, Pablo Cerenzuela, Jose Luis Manzano, Marc Bender, Shan Jiang, Paolo Antonio Ascierto, Iva Gavrilova, Lidija Kandolf, Helen Gogas, Peter Mohr, Dirk Schadendorf, Eva Ellebaek

“…Patients who discontinued adjuvant anti-PD1 for toxicity had a higher ORR (52.9 %) compared to patients who completed the treatment (37.5 %) or discontinued due to disease progression (23.1 %). …”
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Establishment of a survival rabbit model for laryngotracheal stenosis: A prospective randomized study by Wei Chen, Qingyu Wang, Hongming Xu, Yuhui Xie, Lina Zhang, Yao Li, Guofeng Yan, Yiwen Ding, Shunkai Lu, Zhibo Xie, Jiarui Chen, Mengrou Xu, Xiaoben Liang, Juan Chen, Penghuai Fu, Xiaoyan Li, Liming Peng

“…Histological observation showed that the control group had intact laryngotracheal mucosal epithelium without any stenosis; the experimental groups showed proliferation of fibroblasts and thickening of collagen fibers. …”
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Impact of nurturing care educational videos focusing on children with nutritional problems aged 6-23 months on mothers' knowledge and child growth by Fitri Haryanti, Lely Lusmilasari, Sri Hartini, Ayyu Sandhi, Ika Parmawati, Akhmadi Akhmadi, Nisa Nur Hasanah, Fitriana Andarwati, Hani Risnawati, Alissa Nur Pratiwi, Ananda Sekar Kusumawati, Redyta Dwi Cahyani

“…Conclusion: Nurturing care educational videos had a significant positive impact on enhancing mothers' knowledge and promoting child growth. …”
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