Prognostic Factors and Treatment Outcomes in Gallbladder Cancer Patients Undergoing Curative Surgery: A Multicenter Retrospective Cohort Study by Bowen Xu, Yanjiang Yin, Jianping Chang, Zhiyu Li, Xinyu Bi, Jianqiang Cai, Xiao Chen

“…The patients treated after 2017 had a better OS (<i>p</i> = 0.024), possibly due to improved surgical techniques and perioperative care. …”
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Effect of <i>CTLA4</i> gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation by D. S. Romaniuk, A. A. Khmelevskaya, M. Yu. Drokov, N. N. Popova, V. A. Vasilieva, L. A. Kuzmina, G. A. Efimov, E. N. Parovichnikova, V. G. Savchenko

“…The incidence of relapse was also significantly different for the group with A/A genotype and for the group with G/G or A/G genotypes of the nsSNP and equaled to 83.7 and 29.3 % respectively (p = 0.03). …”
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Multicenter research of the dependence of skin graft engraftment and the concentration of blood hemoglobin, total serum protein and albumin by D. O. Vagner, E. V. Zinoviev, V. V. Soloshenko, A. E. Chukharev, V. S. Borisov, M. Yu. Kaplunova, S. B. Bogdanov, A. A. Petrov, N. V. Ostrovsky, E. P. Malyshina, R. D. Ermolova, D. V. Cherdancev, I. V. Vladimirov

“…The concentration of total serum protein (p=0.001) and albumin (p=0.000) had a significant impact on the skin grafting results. …”
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CARDIAC TRANSPLANT REJECTION AND NON-INVASIVE COMON CAROTID ARTERY WALL FUNCTIONAL INDICES by A. O. Shevchenko, I. U. Tunjaieva, A. A. Nasyrova, B. L. Mironkov, I. M. Ilinsky, N. P. Mozhejko, I. I. Muminov, O. P. Shevchenko

“…The later had similar values with cardiac transplant recipients without rejection. …”
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Damaging effect of ischemia on the development of retinal organoids derived from human embryonic stem cells by Yu-Han Yan, Hong-Yu Li, Li-Xiong Gao, Wen Li, Ling-Ping Zhao, Quan Zeng, Yu Luo, Tian-Tian Cui, Ru-Ge Zang, Zi Ye, Jia-Fei Xi, Wen Yue, Zhao-Hui Li

“…Organoids treated with OGD/R on day 30 had similar injuries in retinal structure and retinal cell markers to those on day 18. …”
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Superficial Vein Thrombosis in an Asymptomatic Case of Cholangiocarcinoma with Recent History of COVID-19 by Mihai-Lucian Ciobica, Bianca-Andreea Sandulescu, Mihai Alexandru Sotcan, Lucian-Marius-Florin Dumitrescu, Lucian-George Eftimie, Cezar-Ionut Calin, Mihaela Iordache, Dragos Cuzino, Mara Carsote, Claudiu Nistor, Ana-Maria Radu

“…This is a hybrid type of paper: this clinical vignette is accompanied by two distinct sample-focused analyses as a basis for discussion; they each had different methods depending on their current level of statistical evidence. …”
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A mechanism-based group psychotherapy approach to aggressive behavior (MAAP) in borderline personality disorder: a multicenter randomized controlled clinical trial by Christine Sigrist, Andreas Bechdolf, Katja Bertsch, Robin Bullenkamp, Martin Busse, Ute gr. Darrelmann, Astrid Dempfle, Martin Driessen, Thomas Frodl, Jan-Michael Kersting, Jessica Kesik, Burkhart Matzke, Corinne Neukel, Eva Niessen, Svenja Nückel, Viola Oertel, Frank Padberg, Alexandra Philipsen, Dorothee Pink, Andreas Reif, Matthias Reinhard, Carolin Steuwe, Larissa Wolkenstein, Sabine C. Herpertz, the MAAP Consortium

“…A previously conducted proof-of-concept study had suggested beneficial effects for this neglected group of patients. …”
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Comparison of Raman spectroscopy with mass spectrometry for sequence typing of Acinetobacter baumannii strains: a single-center study by Suling Liu, Ni Zhang, Jiawei Tang, Chong Chen, Weisha Wang, Jingfang Zhou, Long Ye, Xiaoli Chen, ZhengKang Li, Liang Wang

“…Then, a SERS spectral database for all these strains was constructed, and predictive models based on eight ML algorithms were developed to predict SERS signals to determine their STs, among which the support vector machine (SVM) model had the best performance (fivefold cross-validation = 99.74%). …”
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Patient-reported outcome measures for fatigue in patients with chronic kidney disease: a systematic review by Angela Ju, Karine Manera, Armando Teixeira-Pinto, Germaine Wong, Martin Howell, Adeera Levin, Chandana Guha, David C Wheeler, Allison Jauré, Anastasia Hughes, Rosanna Cazzolli, Luca G Torrisi, Rebecca Wu

“…Six measures (Chronic Kidney Disease Symptom Index – Sri Lanka, Functional Assessment of Cancer Therapy – Anemia, Revised Illness Perception Questionnaire, Kidney Symptom Questionnaire, Short Form 6 Dimension and 36-Item Short Form Health Survey) had been validated in patients with CKD not requiring KRT.Conclusion PROMs used to assess fatigue in patients with CKD vary in content and few were specific to fatigue in patients with CKD not requiring KRT. …”
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Associations between prepartum urine pH and periparturient blood calcium concentrations in multiparous Holstein cows by Jesse P. Goff, Pedro Melendez, Julian A. Bartolome, Thomas R. Overton, Brittany M. Leno, Geneva Graef, James K. Drackley, Kristen M. Glosson, Xiangfei Zhang, Stephen J. LeBlanc, Rita Couto-Serrenho, José E. P. Santos, Camilo Lopera, Roney Zimpel, Rachael M. Rodney, Ian J. Lean

“…There was no significant difference in Ca nadir or % of cows with SCH when prepartum urine pH was &lt; 7.75. …”
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Impact of genetic risk and lifestyles on cardiovascular disease-free and total life expectancy: a cohort study by Dong Sun, Qiufen Sun, Yinqi Ding, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y. Millwood, Robin G. Walters, Huaidong Du, Jun Zhang, Dan Schmidt, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, the China Kadoorie Biobank Collaborative Group

“…Correspondingly, compared to those with unfavorable lifestyles, participants with favorable lifestyles had longer total LE and LE without CVD of 3.0 (1.5–4.3) and 4.0 (3.0–4.9) years in women and 5.7 (4.1–7.1) and 5.8 (4.7–6.9) years in men, respectively. …”
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Post-extrasystolic variation of ST segment and T wave as a mortality risk predictor after myocardial infarction by Ralf J. Dirschinger, Ralf J. Dirschinger, Alexander Müller, Petra Barthel, Alexander Steger, Michael Dommasch, Axel Bauer, Karl-Ludwig Laugwitz, Georg Schmidt, Daniel Sinnecker, Daniel Sinnecker

“…The 88 patients with PEST values below this cutoff had a considerably higher mortality than the remainder of the patients (25% vs. 5.8%, p &lt; 0.0001; univariable hazard ratio 4.7, 95% CI 2.4–12.0, p &lt; 0.001). …”
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Tooth loss trajectories and their association with all-cause mortality among older Chinese adults by Xiaoming Zhang, Rui Zeng, Dongmei Ye, Mengxia Shi, Aizhang Zhu, Aizhang Zhu, Lihuan Chen, Tenghui Fan, Ke Zhu, Fayi Xie, Wan Zhu, Yufei Zeng, Yufei Zeng, Jiang Wang, Jiang Wang, Wenwu Zhang

“…Participants were excluded if they had missing data on death, time to death, or if their they reported tooth count showed an abnormally high increase. …”
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Effectiveness of a community health advisor colorectal cancer screening educational intervention on stool test completion in an African American primary care patient population: a... by John S. Luque, Gebre-Egziabher Kiros, Matthew A. Vargas, Askal Ali, Rima Tawk, Deloria R. Jackson, Sabrina L. Dickey, Cynthia M. Harris, Temple Robinson, Bessie Duncan, Jeanne’ Freeman, Clement K. Gwede, Kristin Wallace

“…Results At 12 months (n = 93), completion of the stool test increased significantly among participants in both study arms, showing no difference; 27 out of 45 (60%) participants in the intervention group and 28 out of 48 (58%) participants in the control group (p = 0.87).The intervention had a significant effect on the two secondary outcomes of CRC knowledge (p = 0.03) and CRC perceived susceptibility (p < 0.001) after adjusting for the covariates and confounders included in the model. …”
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Identification and Expression Analysis of the ADH Gene Family in Chinese Pepper(Capsicum chinense) by Chu YE, Wei LIN, Chuan WANG, Bingchun XIE, Xiaowan XU, Xiaomei XU, Hengming WANG, Junheng LYU, Minghua DENG, Zhiming WU, Tao LI, Zhou HENG

“…Identifying the members of the ADH gene family in C. chinense, and analyzing their expression patterns in different parts of the plant will provide references for the aroma synthesis mechanism of pepper fruit.…”
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Physiological and Biochemical Responses of Pseudocereals with C3 and C4 Photosynthetic Metabolism in an Environment with Elevated CO₂ by Bruna Evelyn Paschoal Silva, Stefânia Nunes Pires, Sheila Bigolin Teixeira, Simone Ribeiro Lucho, Natan da Silva Fagundes, Larissa Herter Centeno, Filipe Selau Carlos, Fernanda Reolon de Souza, Luis Antonio de Avila, Sidnei Deuner

“…Both species were taller and had longer roots and a greater dry weight of roots and shoots when under <i>e</i>[CO₂]. …”
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Effects of 4-hydroxyphenylacetic acid, a phenolic acid compound from Yucca schidigera extract, on immune function and intestinal health in meat pigeons by Yuxin Shao, Yipu Li, Shuxian Xie, Bo Zhang, Jing Li, Yalei Wang, Yusheng Gao, Jianyuan Ma, Asmaa Taha Yaseen Kishawy, Lihong Gu, Tenghe Ma, Zheng Wang

“…In vitro experiments showed that 4-HPAA at different levels exhibited higher cell viability than shikimic acid and 3,4-dihydroxybenzoic acid, and with the highest viability observed at 600 μM. …”
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Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. by John R B Perry, Benjamin F Voight, Loïc Yengo, Najaf Amin, Josée Dupuis, Martha Ganser, Harald Grallert, Pau Navarro, Man Li, Lu Qi, Valgerdur Steinthorsdottir, Robert A Scott, Peter Almgren, Dan E Arking, Yurii Aulchenko, Beverley Balkau, Rafn Benediktsson, Richard N Bergman, Eric Boerwinkle, Lori Bonnycastle, Noël P Burtt, Harry Campbell, Guillaume Charpentier, Francis S Collins, Christian Gieger, Todd Green, Samy Hadjadj, Andrew T Hattersley, Christian Herder, Albert Hofman, Andrew D Johnson, Anna Kottgen, Peter Kraft, Yann Labrune, Claudia Langenberg, Alisa K Manning, Karen L Mohlke, Andrew P Morris, Ben Oostra, James Pankow, Ann-Kristin Petersen, Peter P Pramstaller, Inga Prokopenko, Wolfgang Rathmann, William Rayner, Michael Roden, Igor Rudan, Denis Rybin, Laura J Scott, Gunnar Sigurdsson, Rob Sladek, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Jaakko Tuomilehto, Andre G Uitterlinden, Sidonie Vivequin, Michael N Weedon, Alan F Wright, MAGIC, DIAGRAM Consortium, GIANT Consortium, Frank B Hu, Thomas Illig, Linda Kao, James B Meigs, James F Wilson, Kari Stefansson, Cornelia van Duijn, David Altschuler, Andrew D Morris, Michael Boehnke, Mark I McCarthy, Philippe Froguel, Colin N A Palmer, Nicholas J Wareham, Leif Groop, Timothy M Frayling, Stéphane Cauchi

“…For 36 known type 2 diabetes loci, 29 had a larger odds ratio in the lean compared to obese (binomial P = 0.0002). …”
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Efficacy and safety of biosimilar trastuzumab (HLX02) in patients with HER2-positive advanced breast cancer: a retrospective real-world analysis by Xuan Ye, Xuan Ye, Linlin Wang, Wensheng Liu, Wensheng Liu, Mengmeng Wang, Mengmeng Wang, Zihan Guo, Zihan Guo, Han Shan, Han Shan, Qing Zhai, Qing Zhai, Qiong Du, Qiong Du

“…Switching between trastuzumab originator and biosimilar for MBC treatment had no impact on efficacy and did not increase safety risks.…”
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Head injury assessment in youth men's rugby league players: An evaluation of game play characteristics and video review of potential concussion signsKey Points by Andrew J. Gardner, Martin A. Lang, Suzi Edwards, Ben Jones, Grant L. Iverson, Douglas P. Terry

“…Conclusions: In elite-level pathway rugby league, the incidences of HIAs and medically diagnosed concussions were higher in the under 20 age group than the under 18 age group. Both age groups had lower incidences of HIAs and concussions than professional adult rugby league players. …”
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