Immune histories and natural infection protection during the omicron era by Hiam Chemaitelly, Houssein H. Ayoub, Niklas Bobrovitz, Peter Coyle, Patrick Tang, Mohammad R. Hasan, Hadi M. Yassine, Asmaa A. Al Thani, Zaina Al-Kanaani, Einas Al-Kuwari, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F. Abdul-Rahim, Gheyath K. Nasrallah, Mohamed Ghaith Al-Kuwari, Hamad Eid Al-Romaihi, Mohamed H. Al-Thani, Abdullatif Al-Khal, Roberto Bertollini, Adeel A. Butt, Laith J. Abu-Raddad

“…This study investigated how different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) natural infection histories before an omicron infection, with or without vaccination, influence protection against subsequent omicron reinfection. …”
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The Association between Metabolic Syndrome and Morbid Events in Type 2 Diabetes after a 7-Year Community Management: Beijing Community Diabetes Study 17 by Guang-Ran Yang, Ming-Xia Yuan, Han-Jing Fu, Gang Wan, Dongmei Li, Timothy D. Dye, Liang-Xiang Zhu, Rong-Rong Xie, Yu-Jie Lv, Jian-Dong Zhang, Xue-Ping Du, Yu-Ling Li, Yu Ji, Yue Li, Xue-Li Cui, Zi-Ming Wang, Shu-Yan Cheng, De-Yuan Liu, Qian Wang, Li Zhou, Ying Gao, Shen-Yuan Yuan

“…Conclusions. T2DM with MS had higher incidence of morbid events, especially cardiovascular events, even after integrated management. …”
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Degassing and Cycling of Mercury at Nisyros Volcano (Greece) by A. L. Gagliano, S. Calabrese, K. Daskalopoulou, J. Cabassi, F. Capecchiacci, F. Tassi, S. Bellomo, L. Brusca, M. Bonsignore, S. Milazzo, G. Giudice, L. Li Vigni, F. Parello, W. D’Alessandro

“…Total Hg concentrations in plant leaves (0.010-0.112 μg/g) had no direct correlation with soil Hg, with Cistus leaves containing higher values of Hg with respect to Erica. …”
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Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease by Carlos Cepeda, Sandra M. Holley, Joshua Barry, Katerina D. Oikonomou, Vannah-Wila Yazon, Allison Peng, Deneen Argueta, Michael S. Levine

“…In striatal medium-sized spiny neurons (MSNs), a different picture emerged. Intrinsic membrane properties were relatively normal throughout development, except for a transient increase in membrane capacitance at P14. …”
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Factors Associated with Impaired Humoral Immune Response to mRNA Vaccines in Patients with Inflammatory Bowel Disease: A Matched-Cohort Analysis from the RisCoin Study by Katarina Csollarova, Leandra Koletzko, Thu Giang Le Thi, Paul R. Wratil, Ana Zhelyazkova, Simone Breiteneicher, Marcel Stern, Gaia Lupoli, Tobias Schwerd, Alexander Choukér, Veit Hornung, Oliver T. Keppler, Kristina Adorjan, Helga Paula Török, Sibylle Koletzko

“…<b>Results</b>: At baseline, IBD patients treated with anti-TNF but not those under vedolizumab or ustekinumab therapy had lower anti-spike levels compared to HCW-healthy and HCW-plus (166 versus 1384 and 1258 BAU/mL, respectively; <i>p</i> < 0.0001). …”
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Exploration of the clinical prognostic model of BRCA based on PCAT7 by Zhi Zhang, Chaocheng Xiang, Tong Chen, Aimin Ma, Xu Wang, Jiaying Li, Yixuan Chen, Yixuan Chen, Chengyu Huang, Chengyu Huang, Ting Li, Ting Li, Danmei Wu, Steven Mo, Dequan Li

“…Pivot analysis based on a hypergeometric approach was used to identify lncRNAs, TFs and RBPs that regulate the set of prognosis-related genes to explore drug targets.ResultsThe results showed that PCAT7 was significantly high expression in BRCA, and patients with high expression of PCAT7 had poor prognosis. IHC further confirmed that PCAT7 was significantly overexpressed in BRCA samples of different subtypes, suggesting that PCAT7 has diagnostic potential in BRCA. …”
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Comparison of diagnostic algorithms in clinically suspected viral myocarditis: Agreement between cardiovascular magnetic resonance, endomyocardial biopsy, and troponin T by Hafisyatul Zainal, Andreas Rolf, Hui Zhou, Moises Vasquez, Felicitas Escher, Till Keller, Mariuca Vasa-Nicotera, Andreas M. Zeiher, Heinz-Peter Schultheiss, Eike Nagel, Valentina O. Puntmann

“…Results: A total of 114 patients (age (mean ± SD) 54 ± 16, 65% males) were included, of which 79 (69%) had positive EMB criteria, 64 (56%) CMR criteria, and a total of 58 (51%) positive troponin. …”
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Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial by Jordan M. Cloyd, MD, Rakhsha Khatri, BA, Angela Sarna, BS, Lena Stevens, PhD, Victor Heh, PhD, Mary Dillhoff, MD, Alex Kim, MD, Timothy M. Pawlik, MD, PhD, MPH, Aslam Ejaz, MD, Sharla Wells-Di Gregorio, PhD, Erin Scott, MD, Sachin S. Kale, MD

“…This single-institution prospective clinical trial enrolled adult patients with gastrointestinal or hepatopancreatobiliary cancer with no prior PC exposure who had curative-intent oncologic surgery that was unexpectedly aborted. …”
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Risk thresholds for soft versus hard cardiovascular disease outcome models for initiating statin therapy among Chinese adults: a cost-utility analysis by Zhijia Sun, Haijun Zhang, Yinqi Ding, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Dan Huang, Xiaoming Yang, Maxim Barnard, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, on behalf of the China Kadoorie Biobank Collaborative Group

“…We used CKB-ASCVD models to predict 10-year risk and different risk thresholds to guide statin initiation. …”
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Developing and validating machine learning models to predict next-day extubation by Samuel W. Fenske, Alec Peltekian, Mengjia Kang, Nikolay S. Markov, Mengou Zhu, Kevin Grudzinski, Melissa J. Bak, Anna Pawlowski, Vishu Gupta, Yuwei Mao, Stanislav Bratchikov, Thomas Stoeger, Luke V. Rasmussen, Alok N. Choudhary, Alexander V. Misharin, Benjamin D. Singer, G. R. Scott Budinger, Richard G. Wunderink, Ankit Agrawal, Catherine A. Gao, NU SCRIPT Study Investigators

“…We compared model predictions and actual events to examine how model-driven care might have differed from actual care. Our internal cohort included 448 patients and 3,095 ICU days, and our external test cohort had 333 patients and 2,835 ICU days. …”
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First documentation of a clinical multidrug-resistant Enterobacter chuandaensis ST2493 isolate co-harboring bla NDM-1 and two bla KPC-2 bearing plasmids by Ruyan Chen, Chenyu Li, Hao Xu, Ruishan Liu, Haoyu Ge, Jie Qiao, Yi Liu, Xiaojing Liu, Lei Fang, Yanhao Shen, Xiaobing Guo

“…The bla NDM−1-bearing plasmid had the potential to transfer and can remain stable after successive passages. …”
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Safety and Efficacy of Cobalt Chromium Everolimus‐Eluting Stents for Treatment of In‐Stent Restenosis: An ILUMIEN IV Substudy by Ziad A. Ali, Ulf Landmesser, Akiko Maehara, Doosup Shin, Koshiro Sakai, Mitsuaki Matsumura, Richard A. Shlofmitz, Giuseppe Calligaris, Aziz Maksoud, Youssef S. Abdelwahed, Paolo Canova, Nieves Gonzalo, Fernando Alfonso, Khady N. Fall, Bassem Chehab, Robert J. McGreevy, Robert W. McNutt, Hong Nie, Jin Wang, Jana Buccola, Gregg W. Stone

“…Compared with non‐ISR lesions, ISR lesions treated with EES had a smaller postpercutaneous coronary intervention minimal stent area although stent expansion and 1‐year target lesion failure rates were not different. …”
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Tenascin-C-Matrix Metalloproteinase-3 Phenotype and the Risk of Tendinopathy in High-Performance Athletes: A Case–Control Study by Lucas Rafael Lopes, Marcus Vinícius Galvão Amaral, Rodrigo Araujo Goes, Valéria Tavares, Francisca Dias, Rui Medeiros, Daniel Escorsim Machado, Jamila Alessandra Perini

“…Athletes with tendinopathy who had the <i>TNC-A/MMP3-T</i> interaction were more prone to experiencing more than three disease exacerbations (OR: 4.3; 95% CI: 1.8–10.5) compared to <i>TNC-A/TNC-C</i>. …”
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Sucrose synthase gene family in common bean during pod filling subjected to moisture restriction by Norma Cecilia Morales-Elias, Eleazar Martínez-Barajas, Lilia Angélica Bernal-Gracida, Monserrat Vázquez-Sánchez, Iris Grisel Galván-Escobedo, Jose Salud Rodriguez-Zavala, Amelia López-Herrera, Cecilia Beatriz Peña-Valdivia, Antonio García-Esteva, Carlos Alberto Cruz-Cruz, María Teresa González-Arnao, José Cruz Jiménez-Galindo, Daniel Padilla-Chacón

“…Seven PvSUS genes were located on six different chromosomes and had 8–16 intron–exon structures (8–16 exons). …”
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One-Off Irrigation Combined Subsoiling and Nitrogen Management Enhances Wheat Grain Yield by Optimizing Physiological Characteristics in Leaves in Dryland Regions by Ming Huang, Shuai Zhang, Mengqi Yang, Yuhao Sun, Qinglei Xie, Cuiping Zhao, Kaiming Ren, Kainan Zhao, Yulin Jia, Jun Zhang, Shanwei Wu, Chunxia Li, Hezheng Wang, Guozhan Fu, Muhammad Shaaban, Jinzhi Wu, Youjun Li

“…One-off irrigation combining subsoiling and N180 had no significant difference relative to one-off irrigation combining subsoiling and N240, while it significantly increased grain yield by 47.1% over the three years, as well as increasing the activities of SOD, POD, and CAT, and Pn in wheat leaves by 23.2%, 41.2%, 26.1%, and 53.0%, respectively, and decreasing the contents of malondialdehyde (MDA), Pro, and SS by 29.2%, 65.4%, and 18.2% compared to non-irrigation rotary tillage combined with N240 across the two years and three stages. …”
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Endovascular Thrombectomy Versus Best Medical Management in Patients With Large Vessel Occlusion Stroke Presenting Beyond 24 Hours: Results From the TRACK‐LVO Late Multicenter Coho... by Yongbo Xu, Shuling Liu, Adnan I. Qureshi, Pinyuan Zhang, Xiaochen Zhang, Shuai Liu, Yuanyuan Xue, Fanlei Meng, Guodong Xu, Yongchang Liu, Youquan Gu, Yibin Cao, Yanzhao Xie, Zhen Hong, Wanchao Shi, Yan Wang, Huisheng Chen, Ming Wei

“…However, the EVT group had an increased risk of symptomatic intracranial hemorrhage compared with the BMM group (adjusted odds ratio, 8.72 [95% CI, 1.04–73.10]; P = 0.046). …”
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Improving SARS-CoV-2 variants monitoring in the absence of genomic surveillance capabilities: a serological study in Bolivian blood donors in October 2021 and June 2022 by Lucia Inchauste, Elif Nurtop, Lissete Bautista Machicado, Yanine Leigue Roth, Shirley Lenz Gonzales, Maria Luisa Herrera, Katty Mina Villafan, Pedro Mamani Mamani, Marcelo Ramos Espinoza, Juan Carlos Pavel Suarez, Juan Cansio Garcia Copa, Yitzhak Leigue Zabala, Etzel Arancibia Cardozo, Pierre Gallian, Xavier de Lamballerie, Stéphane Priet

“…The funders of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report.…”
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Cost‐effectiveness analysis of a community‐based model for delivery of antiretroviral therapy to people with clinically stable HIV in Cambodia by Lo Yan Esabelle Yam, Pheak Chhoun, Ziya Tian, Michiko Nagashima‐Hayashi, Marina Zahari, Sovannary Tuot, Sovannarith Samreth, Bora Ngauv, Vichea Ouk, Kiesha Prem, Siyan Yi

“…Abstract Introduction In Cambodia, of all people living with HIV, 89% knew their status, 89% were receiving antiretroviral therapy (ART) and 87% had their viral load suppressed in 2023. In 2017, the national HIV programme introduced the multi‐month dispensing (MMD) model to reduce visits to ART clinics, thereby reducing the burden on people living with HIV and health facilities. …”
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Salinity and inundation drivers shift microbial necromass carbon distribution patterns in estuarine mangrove wetlands by Linke Zheng, Manlin Su, Xiaoting Zhang, Lei Wang, Hualong Hong, Qian Zhang, Lijuan Zhong, Haoliang Lu

“…This inverse relationship suggests differential preservation mechanisms across soil depths. Different salinity and inundation periods induced pronounced responses. …”
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Prognostic implications of the high sensitivity C-reactive protein to albumin ratio for major cardiovascular adverse events in patients undergoing noncardiac surgery by Yingjie Chen, Jingfang Lin, Dongxu Chen, Jundan Jiang, Yongxin Huang, Cansheng Gong, Yawen Xie, Xiaohui Chen, Ting Zheng, Yanling Tang, Xiaochun Zheng, Yanling Liao

“…There was a significant difference in the perioperative MACE risk among the three groups (tertiles 1 to 3: 0.24% vs. 0.69% vs. 1.63%; log-rank P < 0.001). …”
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