Prevalence and management of ectopic and molar pregnancies in 17 countries in Africa and Latin America and the Caribbean: a secondary analysis of the WHO multi-country cross-sectio... by Renato T Souza, José Guilherme Cecatti, Özge Tunçalp, Veronique Filippi, Jean-Paul Dossou, Vanessa Brizuela, Adama Baguiya, Philip Govule, Hedieh Mehrtash, Kwame Adu-Bonsaffoh, Luis Bahamondes, Luiz Francisco Baccaro, Charles M'poca Charles, Camila Ayume Amano Cavalari, Luis Henrique Leão

“…At admission, 49.8% of EP had signs of peritoneal irritation. The most common surgical management for EP was laparotomy (87.2%) and for MP, uterine evacuation (89.8%). …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…Three independent patient-derived LCs had similar effects, albeit to varying degrees, highlighting the patient-specific properties of this type of amyloids. …”
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Extramedullary plasmacytoma in children is a genetically distinct localized neoplasia curable by surgical resection by Ilske Oschlies, Julia Richter, Amelie Alfert, Fernando Chahud, Stephanie Mueller, Ingrid Simonitsch-Klupp, Hannah von Mersi, Andishe Attarbaschi, Karoline Koch, Christoph Schaefers, Monika Brüggemann, Cecilia Bozzetti, Wilhelm Woessmann, Birgit Burkhardt, Wolfram Klapper

“…One patient with EMP of the tonsils had a concurrent Epstein-Barr virus infection. Twelve of 13 patients with follow-up information reached sustained complete remissions after surgical resection (median follow-up, 38 months). …”
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Phyllotaxy and environmental factors influences on leaf trait dimensions in Fraxinus mandshurica: a multidimensional approach within temperate forests by Mingyue Jin, Mingyue Jin, Mingyue Jin, Yunfei Diao, Yunfei Diao, Yunlong Wang, Mingke Zhang, Tianyi Wang, Yajun Ren, Yajun Ren, Yajun Ren, Ming Zhong, Ming Zhong, Ming Zhong, Wanting Cheng, Wanting Cheng, Wanting Cheng, Chengdong Wang, Chengdong Wang, Chengdong Wang, Honghui Teng, Honghui Teng, Honghui Teng

“…No significant variation in the dimensions of economic and stomatal traits was observed across the phyllotaxy gradient; (2) phyllotaxy modulates trait coordination, with decoupled economic and stomatal traits at phyllotaxy 1 but coupled relationships at phyllotaxy 2–6; (3) environmental factors had a greater impact on economic trait dimensions variation, whereas phyllotaxy was more important for stomatal trait dimensions.DiscussionOur study highlights the significance of trait dimensions in understanding plant functional strategies. …”
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Blastemal predominant WT1 negative Wilms tumour of the young adult: a unique case report and review of the literature by Jozef Škarda, Jozef Škarda, Michal Grepl, Michal Grepl, Valeria Skopelidou, Valeria Skopelidou, Vladimír Židlík, Vladimír Židlík, Vladimír Židlík, Pavel Hurník, Pavel Hurník, Pavel Hurník, Daniela Skanderová, Daniela Skanderová, Michael Michal, Michael Michal, Michal Michal, Michal Michal, Pavla Hanzlíková, Pavla Hanzlíková, Jana Vaculová, Jana Vaculová, Marcel Mitták, Marcel Mitták

“…However, none of the patients had a blastemal predominant tumour. That is why we would like to present a highly interesting and diagnostically challenging case of a young man who was diagnosed with a tumorous lesion of the left kidney parenchyma. …”
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Association of Rare NOTCH3 Variants With Prevalent and Incident Stroke and Dementia in the General Population by Pei Wang, Ming Yao, Jing Yuan, Fei Han, Fei‐Fei Zhai, Ding‐Ding Zhang, Li‐Xin Zhou, Jun Ni, Shu‐Yang Zhang, Li‐Ying Cui, Yi‐Cheng Zhu

“…There was no statistical difference in the change in longitudinal cognitive scale scores. …”
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Effect of omicron infection on maternal and neonatal delivery outcomes: A retrospective cohort study by Jing Wang, Lingfei Ge, Kai Zhou, Yi Jiang, Mengqi Pang, Jiaqi Wang, Yuxian Zhu, Lingli Zhu, Xiaoxiao Jin, Zeying Chai, Tao Hsin Tung, Hongping Lu, Bo Shen, Lingzhi Zheng

“…Delivery outcomes did not differ whether the infected pregnant women were in the acute phase and whether to use antipyretics. …”
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New Surgical Criteria for Intraductal Papillary Mucinous Neoplasm Based on the Age-Adjusted Charlson Comorbidity Index Values and Presence of Solid Component by Hiroyuki Hasegawa, Mitsuharu Fukasawa, Shinichi Takano, Satoshi Kawakami, Natsuhiko Kuratomi, Shota Harai, Dai Yoshimura, Naoto Imagawa, Tetsuya Okuwaki, Toru Kuno, Yuichiro Suzuki, Takashi Yoshida, Shoji Kobayashi, Mitsuaki Sato, Shinya Maekawa, Naohiro Hosomura, Hiromichi Kawaida, Daisuke Ichikawa, Nobuyuki Enomoto

“…In the presence of an SC, the surgical group had a significantly better OS than the non-surgical group (estimated 5-year OS, 38% vs. 18%; <i>p</i> = 0.031). …”
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Experimental effects of multiple agricultural stressors on diversity and size structure of subtropical stream macroinvertebrates by Gabrielle S.S. Almeida, Victor S. Saito, Milena Sartori, Hugo H.L. Saulino, Lyandra O. da Penha, Paulo S.C.T. Miranda, Mariana Morilla, Maria Gabrielle Rodrigues-Maciel, Giovanna Collyer, Marcelo S. Moretti, Fabiana Schneck, Jeremy J. Piggott, Iris Madge Pimentel, Christoph D. Matthaei, Silvio F.B. Ferraz, Ricardo H. Taniwaki

“…Our findings revealed that the macroinvertebrate community was affected by all three stressors, with each one influencing different structural aspects of the community. Nitrate addition had a positive effect on community evenness up to moderate enrichment levels. …”
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Lactobacillus helveticus mitigates diarrhea and inflammation induced by enterotoxigenic E. coli through rebalance of gut microbiota by Zhen Zhang, Jianmin Lv, Xin Wang, Ling Chun, Qiannan Yang, Huarui Zhao, Siming Xue, Ziyi Zhang, Xiaobo Liu, Shiwei Wang, Yanmei Sun

“…Here, we compared the anti-diarrheal efficacy of four L. helveticus strains (H1-H4) isolated from different geographical origins to unravel the mechanisms of action in ETEC-infected mice. …”
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A discrete choice experiment on Chinese parents' preferences of vaccine schedules against six childhood infectious diseases by Aodi Huang, Lin Tang, Lifang Huang, Jun Li, Xue Zhang, Jiajie Liu, Yang Zhou, Bingling Zhang, Lei Wang, Qian Zhang, Xia Xu, Zemei Zhou, Yu Wang, Xiaoqi Wang, Qianqian Liu, Siyu Liu, Zundong Yin, Fuzhen Wang

“…We used a mixed logit model to determine parental preferences for vaccination schedules, relative importance of attributes, and predict the likelihood of successful vaccination under different scenarios. Results: A total of 581 parents from seven provinces and cities in China participated in the survey, and 488 respondents had internally consistent responses and were included in the analysis. …”
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Esketamine nasal spray compassionate use program in the Netherlands: An open label, multi-center cohort study in severe treatment-resistant depression by Abel (K.A.J.) Busz, Emma (E.J.) Schmidt, Rob (R.H.S.) van den Brink, Karen (K.) Foeken, Marasha (M.) de Jong, Joost (J.B.C.) Mertens, Martijn (M.S.) van Noorden, Etienne (E.J.F.L.) Olivier, Koen (K.R.J.) Schruers, Sara (S.I.J.) Schutters, Joris (J.) van Son, Wessel (W.J.) Strootker, Harry (H.C.P.) Venema, Dieuwertje (D.A.) de Waardt, Jasper (J.B.) Zantvoord, Danielle (D.) Cath, Henricus (H.G.) Ruhe

“…Results: Baseline mean MADRS score was 33.6 ± 5.3 and 64.3 % of the population had a history of ≥5 failed AD treatments. At 28 days, a significant decrease of 10.1 (7.3–12.6) MADRS-points was observed (Cohen's d 1.9, 95 % CI: 0.26–0.45, t = 7.20, p < .001). …”
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Role of functional mapping on Gallium-68 perfusion positron emission tomography and computed tomographic imaging (PET/CT) to assess the risk of long-term radiation-induced lung tox... by François Lucia, David Bourhis, Frédérique Blanc-Béguin, Gaëlle Goasduff, Mohamed Hamya, Simon Hennebicq, Maëlle Mauguen, Romain Floch, Margaux Geier, Ulrike Schick, Maëlys Consigny, Olivier Pradier, Grégoire Le Gal, Pierre-Yves Salaun, Vincent Bourbonne, Pierre-Yves Le Roux

“…Results: Out of the 59 patients included, 50 were still alive at 12 months and 9 (18 %) had grade ≥2 long-term RILT. The MD and the VxGy in the AV and LFV were not statistically different in patients with and without long-term RILT (p > 0.05). …”
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Can Aluminum Affect Social Behavior and Cortisol Plasma Profile in the Neotropical Freshwater Teleost <i>Astyanax lacustris</i> (Teleostei: Characidae)? by Natália Pires Vieira Morais de Faria, Bruno Cavalheiro Araújo, Bianca Mayumi Silva Kida, Raisa Pereira Abdalla, Diego dos Santos Brito, Renata Guimarães Moreira, Renato Massaaki Honji

“…Regarding cortisol plasma concentration, males had higher cortisol plasma concentrations than females in the CTL/n and pH/ac groups, which was not observed in the Al/ac group. …”
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Molecular investigation on measles cases rise and variants co-circulation in the Lazio region, Italy by Cesare Ernesto Maria Gruber, Silvia Gioacchini, Lavinia Fabeni, Martina Rueca, Licia Bordi, Eleonora Lalle, Melissa Baggieri, Paola Bucci, Raoul Fioravanti, Roberto Giuseppetti, Eliana Specchiarello, Pietro Giorgio Spezia, Giulia Berno, Fabrizio Carletti, Gabriella De Carli, Maria Concetta Fusco, Alessandra Barca, Paola Scognamiglio, Antonella Marchi, Emilio D’Ugo, Enrico Girardi, Francesco Vairo, Fabio Magurano, Fabrizio Maggi

“…Several mutational patterns were identified, one of which had three nucleotide mutations potentially affecting the diagnostic test. …”
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Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and De... by Anastasia V Pavlova, Stella G Muthuri, Rachel Cooper, Fiona R Saunders, Jennifer S Gregory, Rebecca J Barr, Kathryn R Martin, Judith E Adams, Diana Kuh, Rebecca J Hardy, Richard M Aspden

“…In conclusion, sagittal spine shapes had different associations with total and central adiposity; earlier onset of overweight and prior measures of WC were particularly important.…”
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The Effectiveness of Positive Psychotherapy on Physical and Emotional Dimensions of Girls with Persistent Depression by Froogh Abiri Bonab, Marziyeh Alivandi Vafa, Ali Khademi, Gholam Hossein Javanmard

“…However, no significant difference was observed in the effects of this intervention on physical symptoms between the groups that received individual versus group interventions; both formats had similar effects on the physical dimensions of the participants. …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Of 290 AEs occurring across both treatment arms, 265 (91%) required no action, 22 (8%) had treatment interrupted/dose reduced and 3 (1%) had Investigative Medicinal Product withdrawn. …”
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Assessment of Immunoscore, MRI Tumor Regression Grade, and Neoadjuvant Rectal Score in Predicting Pathologic Response in Locally Advanced Rectal Cancer in the Averectal Study by Mustafa Natout, Ahmad Machmouchi, Hero Hussain, Laudy Chehade, Noura Abbas, Rim Turfa, Joseph Kattan, Sally Temraz, Ayman Tawil, Mousa Elkhaldi, Omar Jaber, Rula Amarin, Tala Alawabdeh, Maya Charafeddine, Monita Al Darazi, Ali Shamseddine

“…All of the patients who achieved pCR had a low or intermediate pathologic NAR score with a significant correlation between pCR and pathologic NAR scores (<i>p</i> < 0.0001). …”
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Unraveling gene expression and physio-biochemical responses in citrus species under water stress and water recovery conditions by Nirmala Friyanti Devy, Hardiyanto, Farida Yulianti, Agus Sugiyatno, Ismon Lenin, Emi Budiarti, Anang Triwiratno, Mutia Erti Dwiastuti, Baswarsiati, Sri Widyaningsih, Chaireni Martasari

“…Meanwhile, studies on the response of gene expression and physio-biochemical traits in citrus seedlings derived from different species to water stress are limited. This study aims to fill that gap, exploring how drought and water recovery treatments affect citrus species. …”
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