Evaluating the efficacy of dilute povidone-iodine versus normal saline for preventing surgical site infections following appendectomy: a prospective observational study in Ghanaian... by Sulemana Abdul-Latif, Joseph Yorke, Samuel Gyasi Brenu, Joseph Kwaku Oppong, Tonnies Abeku Buckman, Francis Somiah-Kwao Aitpillah, Jonathan Laryea, Gifty Kwakye, Michael Ofoe Adinku, Frank Enoch Gyamfi, Kwabena Agbedinu, Francis Akwaw Yamoah, Ishmael Kyei, Samuel Mensah, Charles Kofi Dally, Anita Eseenam Agbeko, Dominic Akuoku Darkwa, Kingsley Bosompem, Dennis Afful Yorke, Akwasi Opoku Agyapong, Nana Akosua Oppong-Nkrumah, Martin Kofi Adjei, Theodora-Ann Fremponma Ellis, Wilfred Sam-Awortwi Jnr, Yaa Takyi Baffowa

“…The overall incidence of SSI was 8.04% (10.7% in the N/S group and 5.4% in the PI group). Both groups had a higher percentage of male patients (58% in the N/S group and 58.9% in the PI group). …”
Get full text

Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning by Qiyuan Tian, Chanon Ngamsombat, Hong-Hsi Lee, Daniel R. Berger, Yuelong Wu, Qiuyun Fan, Berkin Bilgic, Ziyu Li, Dmitry S. Novikov, Els Fieremans, Bruce R. Rosen, Jeff W. Lichtman, Susie Y. Huang

“…Myelinated axons longer than 10 μm had inner diameters around 0.5 µm, outer diameters around 1 µm, and g-ratios around 0.5. …”
Get full text

The efficacy and safety of rituximab monotherapy in the new onset pediatric idiopathic nephrotic syndrome: a randomized controlled clinical trial by Ai-Qin Sheng, Fei Liu, Qiu-Yu Li, Ya-Lan Dou, Xiao-Jing Zhang, Jing-Li Zhao, Ling-Fei Huang, Si-Yi He, Zhi-Hong Lu, Chun-Yue Feng, Jing-Jing Wang, Hui-Jun Shen, Hai-Dong Fu, Wei-Li Yan, Jian-Hua Mao

“…Compared with the RTX group, the GC group had a shorter time to first remission (14.25 d vs. 9.5 d). …”
Get full text

Job satisfaction of healthcare professionals in palliative care departments and factors affecting job satisfaction during COVID-19 pandemic by Sinanović Šćepan, Kilibarda Tatjana, Bubanj Saša, Prodović Tanja, Potić Srećko, Sekulić Jelena, Spasić Marko, Subotić Slobodan, Kostić Marina, Petrović Marko, Popović-Ilić Tatjana, Tomović Milena, Aksović Nikola, Milovanović Olivera

“…Background/Aim. The COVID-19 pandemic had a significant impact on the healthcare system, particularly healthcare providers such as nurses/medical technicians, who were obliged to adhere to strict procedures and manage their time effectively during shifts. …”
Get full text

A retrospective study on beta-blocker use and outcomes in hematopoietic stem cell transplant patients by Matthew A. Bergens, John T. Bokman, Ernaya J. Johnson, Matthew L. Braun, Yan Li, Amy T. Bush, Lauren Hill, Jolien Van Opstal, Alessandro Racioppi, Rebecca Fan, Sejal Kaushik, Edwin Alyea, Nelson Chao, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Richard Lopez, Sendhilnathan Ramalingam, Keith Sullivan, Paul Wischmeyer, Anthony D. Sung

“…We analyzed 10 years of data (January 2010 to May 2020), including 105 patients who received a BB for more than four days before and after HCT, and 669 control patients who did not receive a BB. Patients on BBs had a lower incidence of aGVHD (55.2% vs. 65.8%, p = 0.036); however, this difference was not statistically significant in multivariate analysis (p = 0.150). …”
Get full text

Prevalence and sequence of chronic conditions in older people with dementia: a multi-province, population-based cohort study by Susan E. Bronskill, Azmina Artani, Laura C. Maclagan, Xuesong Wang, Hannah Chung, J. Michael Paterson, Andrea Gruneir, Karen A. Phillips, Rasaq Ojasanya, Xibiao Ye, Kayla McLean, Fernanda Ewerling, Claire Godard-Sebillotte, Victoria Massamba, Louis Rochette, Isabelle Vedel, Larry Shaver, Catherine Pelletier, Colleen J. Maxwell

“…Individuals with high coping had a life satisfaction score between 0.84 and 1.32 units greater than individuals with lower coping. …”
Get full text

Role of CD8 Regulatory T Cells versus Tc1 and Tc17 Cells in the Development of Human Graft-versus-Host Disease by Adriana Gutiérrez-Hoya, Rubén López-Santiago, Jorge Vela-Ojeda, Laura Montiel-Cervantes, Octavio Rodríguez-Cortés, Víctor Rosales-García, Vladimir Paredes-Cervantes, Raúl Flores-Mejía, Daniela Sandoval-Borrego, Martha Moreno-Lafont

“…This study analyzes the prominent role of these different subpopulations in the development of graft-versus-host disease (GVHD). …”
Get full text

Gynecologic and obstetric complications in women with congenital fibrinogen disorders: insights from the Prospective Rare Bleeding Disorders Database by Samin Mohsenian, Roberta Palla, Marzia Menegatti, Andrea Cairo, Simona Maria Siboni, Marguerite Neerman-Arbez, Mehran Karimi, Helen Pargantou, Rosanna Asselta, Danijela Mikovic, Marko Saracevic, Britta Laros-van Gorkom, Laura Jacobs, Amy Shapiro, Adrianna Williamson, Michael Makris, Alessandro Casini, Flora Peyvandi

“…Results: A total of 59 women (8 afibrinogenemic, 15 hypofibrinogenemic, and 36 dysfibrinogenemic cases) were investigated, of which 32 patients had 70 pregnancies. The prevalence of heavy menstrual bleeding was comparable between hypofibrinogenemic (27%) and dysfibrinogenemic (36%) cases, with a higher frequency in afibrinogenemic (75%) cases. …”
Get full text

Physiological and biochemical responses to cold stress in sesame (Sesamum indicum L.) during the early growth stage by Ahmed A. Abbas, Muez Berhe, Habtamu Kefale, Somaya A. Hussien, Rong Zhou, Ting Zhou, Huan Li, Yanxin Zhang, Zhongbo Guan, Chris O. Ojiewo, Jun You, Linhai Wang

“…Cold stress significantly impacts sesame during its early growth stages, with varying responses observed among different genotypes. Ten genotypes were evaluated for phenotypic response to various temperatures during germination. …”
Get full text

Time to treatment in pediatric patients with repeated episodes of status epilepticus by Jennifer V. Gettings, Iván Sánchez Fernández, Anne Anderson, J. Nicholas Brenton, Afra Can, Justice Clark, Raquel Farias Moeller, Howard P. Goodkin, Yi-Chen Lai, Mohamad A. Mikati, Lindsey A. Morgan, Edward Novotny, Adam P. Ostendorf, Juan Piantino, James J. Riviello, Kumar Sannagowdara, Robert C. Tasker, Dmitry Tchapyjnikov, Mark S. Wainwright, Angus Wilfong, Korwyn Williams, Bo Zhang, Tobias Loddenkemper, Marina Gaínza-Lein, on behalf of Pediatric Status Epilepticus Research Group (pSERG)

“…Results Out of 504 status epilepticus episodes in 420 patients, 50 patients (10.3%) had repeated episodes of status epilepticus. The only predictor of repeated status epilepticus was a prior diagnosis of epilepsy. …”
Get full text

Soil Biocrusts May Exert a Legacy Impact on the Rhizosphere Microbial Community of Plant Crops by Xiangbo Zou, Xinyu Jiang, Heng Jiang, Cheng Li, Jiong Cheng, Dongqing Ji, Jin Wang, Jiajin Ruan, Tiancheng Zhou, Cao Kuang, Ji Ye, Shiqin Yu

“…The results showed that soils with biocrust had significantly higher organic matter, total nitrogen, alkaline hydrolyzable nitrogen, total phosphorus, and total potassium content. …”
Get full text

A phase 3 randomized, open-label study evaluating the immunogenicity and safety of concomitant and staggered administration of a live, pentavalent rotavirus vaccine and an inactiva... by Shaomin Chen, Zhifang Ying, Yan Liu, Yuan Li, Yebin Yu, Meilian Huang, Zhuhang Huang, Zhiqiang Ou, Yuyi Liao, Yong Zhang, Guixiu Liu, Weiwei Zhao, Rong Fu, Qiong Shou, Minghuan Zheng, Xueyan Liao, Yingmei Tu, Jon Stek, Jonathan Hartzel, Changgui Li, Jikai Zhang

“…At PD3, geometric mean titers (GMTs) of nAb responses to poliovirus types 1, 2, and 3 in the concomitant-use group and the staggered-use group were comparable; 100% of participants had nAb titers ≥1:8 and ≥1:64 for all poliovirus types. …”
Get full text

Plants Utilization and Perceptions in the Context of Novel Indigenous Food Spicing and Flavoring Among the Vhavenḓa People in the Vhembe Biosphere Reserve, South Africa by Mueletshedzi Manyaga, Ncobile Pretty Mhlongo, Maropeng Erica Matlala, Nonhlanhla Prudence Lubisi, Vhuhwavho Gelebe, Christeldah Mkhonto, Elizabeth Kola, Wilfred Otang Mbeng, Peter Tshepiso Ndhlovu, Salmina Ngoakoana Mokgehle, Maakanye Millicent Matlanyane, Ndivhuwo Liuvha, Nomusa Rhoda Dlamini, Luambo Jeffrey Ramarumo

“…No study had ever reported the uses of <i>Lannea edulis</i> (Sond.) …”
Get full text

Elevated serum levels of interleukin-18 discriminate Still’s disease from other autoinflammatory conditions: results from the European ImmunAID cohort by Bruno Fautrel, David Saadoun, Tadej Avcin, Thierry Martin, Eric Hachulla, Cem Gabay, Seza Ozen, Stéphanie Humblet-Baron, Carine Wouters, Adrian Liston, Umut Kalyoncu, Jordi Antón, Sinisa Savic, Yvan Jamilloux, Christoph Kessel, Dirk Foell, Jeroen Raes, Michael Hofer, Luca Cantarini, Isabelle Kone-Paut, Søren Brunak, Marie-Elise Truchetet, Steven Vanderschueren, Alexandre Belot, Antonella Insalaco, Haner Direskeneli, Irina Giurgea, Sophie Georgin-Lavialle, Serge Amselem, Léa Savey, Pierre Quartier, Anne Boland, Jean-François Deleuze, Sabrina Carpentier, Katerina Laskari, Thomas Henry, Jean-David Bouaziz, Clementien Vermont, Emanuele Bizzi, Helen Lachmann, Nicolas Poursac, Gilles Hayem, Stéphane Mitrovic, Patrick Matthys, Isabella Friis Jørgensen, Emiliana Rodriguez, Philippe Hupé, Paolo Sfriso, Evangelos Andreakos, Antoine Néel, Alina Boteanu, Sara Garcia, Perrine Dusser, Yvonne M Mueller, Peter D Katsikis, Matheus Vieira, Charlotte Girard-Guyonvarc’h, Charlotte Girard, Assunta Caruso, Violeta Bittermann, Sonia Caccia, Arturo Hernandez Cervantes, Emna Chabaane, Fanny Coffin, Dominique de Seny, Henri de Soyres, Marc Dubourdeau, Stefan J Erkeland, Dimitrios I. Fotiadis, Apolline Gallois, Mieke Gouwy, Sonia Karabina, Andres Jimenez Kaufmann, Keshia Koutekissa, Karoline Krause, Thibault Mahevas, Nasima Matsa, Michael F. McDermott, Aura Moreno Vega, Marco Francesco Natale, Maria Papadaki, Costas Papaloukas, Christophe Poulet, Sebastian Proost, Paul Proost, Julien Roméjon, Sarhan Yaiche, Savvas Savvides, Vassili Soumelis, Sigrid Swagemakers, Paul Van Daele, Harmen J. G. vandeWerken, Peter van derSpek, Rogier van Wijck

“…In 10 patients with Still’s disease who had a second blood collection, we found a significant decrease in serum levels of free IL-18 after treatment.Conclusions Our results show that IL-18 can discriminate Still’s disease from other SAID, and free IL-18 levels may be relevant to assess response to therapy in these patients.…”
Get full text

Seroprevalence of measles antibody among immigrants in Gwangju, South Korea by Ran Lee, Ran Lee, Sarah Kim, Hyerin Na, Ji In Seo, Jang Gwon Yoon, Jang Gwon Yoon, A Ram Park, So Hyun Bae, So Yeong Park, Jun Hwi Cho, Jun Hwi Cho, Jin Kim, Seong-Woo Choi, Sun-Seog Kweon, Bongkyu Sun, Kyunghak Kim, Kyung-Hwa Park, Kyung-Hwa Park, Seong Eun Kim, Seong Eun Kim

“…Long-term residents demonstrated higher antibody positivity (92.9%) than other visa categories (p &lt; 0.01), and women had higher seropositivity (85.8%) compared to men (80.0%), with a near-significant difference (p = 0.05).DiscussionThe higher seropositivity observed among long-term residents and women is likely due to prior immunization with the MMR (Measles Mumps Rubella) vaccine, which is recommended to prevent congenital rubella syndrome as part of pre-pregnancy vaccination protocols. …”
Get full text

Hypertrophic cardiomyopathy due to truncating variants in myosin binding protein C: a Spanish cohort by Carles Díez-López, María Luisa Peña-Peña, Hector Bueno, Fernando Arribas Ynsaurriaga, Vicente Climent-Payá, Maria Melendo-Viu, Rafael Salguero-Bodes, María Valverde-Gómez, Jose María Larrañaga-Moreira, Roberto Barriales, Javier Limeres Freire, Pablo Garcia Pavia, Tomas Ripoll, Maria Gallego Delgado, Esther Zorio, Francisco José Bermudez Jimenez, José Manuel García-Pinilla, Irene Méndez Fernández, Maria Sabater-Molina, Ana Perez Asensio, Álvaro Marchán-Lopez, Julián A Palomino Doza

“…Hypertrophy was discrete with a significative difference between probands and relatives (17.5±4 mm vs 14.6±5 mm; p&lt;0.0001). …”
Get full text

Efficacy of acupuncture for cardiopulmonary cerebral resuscitation: A systematic review and meta-analysis by Yunlan Liu, Mengjuan Ren, Zhuoran Kuang, Xufei Luo, Huishan Li, Yikai Zhang, Wanxin Wen, Yefeng Cai, Xiaojia Ni, Yaolong Chen

“…Results: Seven RCTs involving 411 participants who had experienced ROSC were eligible for inclusion. …”
Get full text

Refining Unfavorable Vaginal Microbial Community in Infertile Women Subjected to Precision Probiotic Intervention: An Exploratory Single-Arm, Prospective, Open-Label, Interventiona... by Giovanna Cocomazzi, Viviana Contu, Silvia De Stefani, Lino Del Pup, Matteo Buccheri, Monica Antinori, Lodovico Parmegiani, Daniele De Ruvo, Francesco Marino, Edy Virgili, Christine Allen, Simone Palini, Walter Ciampaglia, Matteo Cerboneschi, Domenico Baldini, Giorgio Maria Baldini, Valerio Pazienza

“…Methods: We recruited 32 women who had previous failed IVF cycles and were scheduled to undergo ART. …”
Get full text

From geriatric assessment to inflammation. A pilot, observational, study about frailty components in older patients with persistent atrial fibrillation by Stefano Fumagalli, Giulia Ricciardi, Claudia Di Serio, Elisa Berni, Giancarlo La Marca, Giuseppe Pieraccini, Riccardo Romoli, Emanuele Santamaria, Giulia Spanalatte, Camilla Cagnoni, Arianna Tariello, Giada Alla Viligiardi, Agostino Virdis, Igor Diemberger, Andrea Ungar, Niccolò Marchionni

“…Second cluster patients had a higher concentration of 13 of the 35 acylcarnitines evaluated and increased 5-year mortality. …”
Get full text

Comparative analysis of antioxidant activity and structural changes of Gastrodiae Rhizoma polysaccharides between sulfur-fumigation and nonsulfur-fumigation by Chunyan Dai, Chunyan Dai, Chunyan Dai, Dan Zhao, Wenping Zhang, Wenping Zhang, Lanping Guo, Chuanzhi Kang, Zhuowen Chen, Zhuowen Chen, Xiuming Cui, Xiuming Cui, Tao Zhou, Chengxiao Wang, Chengxiao Wang, Tingting Xu, Tingting Xu, Tingting Xu, Ye Yang, Ye Yang

“…NMR analyses revealed that the main chain connections of SGCP3 and NGCP3 were both →4)-α-D-Glcp-(1→, and sulfur fumigation increased the number of repeating unit structures →4)-D-Glcp-(1 → in GR polysaccharides. SGCP3 and NGCP3 had the same monosaccharides composition but different molar ratios, with molecular weights of 727,650 and 39,991 Da, respectively. …”
Get full text