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45861
Characterizing populations prioritized for PrEP in 19 African countries: a review of national guidance
Published 2025-01-01“…In contrast, most countries had at least one document indicating that HIV‐serodifferent couples, AGYW and PBFW were only eligible for PrEP if classified as high risk. …”
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45862
Poor performance of PHQ-9 and GAD-7 in screening clinical depression and anxiety among a large sample of Chinese children and adolescents
Published 2025-03-01“…For study subjects of different age, gender, race, and left-behind status, discordant cut-offs were identified. …”
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45863
PALEOTECTONIC AND PALEOGEOGRAPHIC CONDITIONS FOR THE ACCUMULATION OF THE LOWER RIPHEAN AI FORMATION IN THE BASHKIR UPLIFT (SOUTHERN URALS): THE TERRANECHRONE® DETRITAL ZIRCON STUDY...
Published 2018-03-01“…Despite the similar U/Pb ages of the detrital zircons, these two samples considerably differ in their Hf isotopic features and the concentrations of trace elements, which means that the zircons in the studied sandstones are of different geodynamic origin. …”
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45864
From design to 3D printing: A proof-of-concept study for multiple unit particle systems (MUPS) printed by dual extrusion fused filament fabrication
Published 2024-12-01“…The printed model particles had a diameter of 1.27 ± 0.04 mm and a height of 1.05 ± 0.01 mm. …”
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45865
Morphological Features of Red Blood Cells in Patients with Severe Concomitant Injury
Published 2013-06-01“…Eighteen patients (9 men, 9 women) aged 48.6±16.1 years who had sustained severe concomitant mechanical injury (CMI) with different BL volumes and hemodynamic disorders were examined. …”
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45866
Anti-inflammatory effect and a possible mechanism of action of ethowurtzine from the class of hexaazaizowurtzitane derivatives
Published 2025-07-01“…The introduction of ethowurtzine at different concentrations together with LPS dose-dependently reduced the NO production. …”
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45867
A household randomized-control trial of insecticide-treated screening for malaria control in unimproved houses in Tanzania
Published 2025-06-01“…However, school-age children in the ITS arm had lower malaria after the long rains [OR 0.11 (95% CI 0.02–0.73), p = 0.022]. …”
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45868
Effects of Cerebellar Transcranial Magnetic Stimulation on the Motor Function of Patients With Stroke: A Systematic Review and Meta‐Analysis
Published 2025-04-01“…Subgroup analysis of the BBS showed that cTMS had a significant effect on patients with stroke in the subacute phase (p < 0.00001), with improvements observed using HF‐rTMS (p < 0.0001), iTBS (p < 0.00001), and intensities ≤ 80%RMT (< 80% RMT, p < 0.0001; 80% RMT, p < 0.00001). cTMS consistently demonstrated superior effects compared to controls across different intervention durations (5–10 sessions, p = 0.009; 11–20 sessions, p < 0.00001; > 20 sessions, p < 0.00001). …”
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45869
Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer
Published 2025-01-01“…Similarly, UCK2 was also observed to have a negative association with major histocompatibility complex (MHC) genes. We noted that UCK2 had significant correlations with the sensitivity to various anti-cancer drug.ConclusionWe have observed that UCK2 plays pivotal roles in prognosis and tumor immunity, and it is associated with DNA repair and cancer stemness. …”
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45870
Chronic Rhinosinusitis with Nasal Polyps and Biologics: A Call for Better Data Standardisation and Presentation in Clinical Studies
Published 2025-01-01“…Patient selection criteria was not consistent in studies with several heterogeneous disease subgroups of CRSwNP patients present in each study. Different durations of treatment and variable outcome measures also made the comparative assessment of efficacy between different biologics difficult. …”
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45871
Immune cell topography of head and neck cancer
Published 2024-07-01“…While the highest immune infiltrates were observed in the invasive margin for all immune cells, CD163+macrophages and Tregs had the highest tendency to infiltrate the tumor center. …”
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45872
Evaluating the Chinese versions of delirium assessment scales: a diagnostic systematic review
Published 2025-04-01“…Besides, a significant inverse correlation was found between these 13 Chinese-adapted delirium scales and their reference tests, with most studies were over 0.7, and especially 3 studies offered S-CVI and I-CVI value that were all larger than 0.9, indicating a good discriminate validity and content validity, though different cut-off points were recommended by different scales. …”
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45873
Estimated cost-effectiveness of sequential screening for colorectal cancer: evidence from the largest province-wide colorectal cancer screening program in China
Published 2025-02-01“…Individuals are classified as screening-positive if they are high-risk based on APCS or had positive FIT results, and those screening-positive are referred for colonoscopy. …”
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45874
Monthly changes of night heat islands analysis in Isfahan County in the last two decades using the multi-temporal products of the MODIS sensor
Published 2023-12-01“…Then, with the principal component analysis (PCA) method, the seasons and months that have the most influence on the occurrence of heat islands were identified and in order to analyze the trend of this phenomenon, the Mann-Kendall and the Kolmogorov-Smirnov tests were used.Results and Discussion: The findings of the research indicated that the land surface temperature in the last 20 years in Isfahan had an increasing trend with a rate of 4%. However, this trend in the population and urban centers has been completely different from the surrounding areas of Isfahan. …”
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45875
Impact of initial screening strategies on compliance with colonoscopy for colorectal carcinoma in residents aged 50 years and above
Published 2025-02-01“…Multivariate analysis revealed that FOBT positivity had the greatest impact on colonoscopy compliance. …”
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45876
Morrey Award 2023: radial head donor plug for capitellum osteochondral autograft transfer: a cadaveric biomechanical analysis
Published 2024-11-01“…Results: Both surgical approaches had adequate exposure to access the lateral two-third capitellar lesions in all specimens. …”
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45877
ViLR: a novel virtual long read method for breakpoint identification and direct SNP haplotyping in de novo PGT-SR carriers without a proband
Published 2025-03-01“…In contrast to LRS, ViLR is a virtual long read solution that used the same barcoded labeling and assembly of different long gDNAs differently barcoded. Notably, ViLR could generate an average fragment length of over 30 Kb, with an N50 block size of up to 16 Mb in a single assay, allowing to achieve accurate breakpoint mapping and direct carrier’s haplotyping. …”
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45878
The inhibitory effect of tyrosine kinase inhibitors on angiogenesis in zebrafish and interrelationship with the activation of the PI3K/AKT pathway
Published 2025-08-01“…Conclusions Dovitinib and Telatinib exhibit significant anti-angiogenic effects, while Lapatinib is less effective. Different TKIs inhibit angiogenesis by regulating different signaling molecules: Dovitinib primarily targets VEGF receptors, Telatinib targets both receptors and the downstream PI3K/AKT pathway, and Lapatinib shows inhibitory effects on VEGF ligand expression in the SC79 background. …”
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45879
Patterns of postmeal insulin secretion in individuals with sulfonylurea-treated KCNJ11 neonatal diabetes show predominance of non-KATP-channel pathways
Published 2019-05-01“…We aimed to assess the physiological response to carbohydrate and protein/fat in people with sulfonylurea-treated KCNJ11 PNDM.Research design and methods 5 adults with sulfonylurea-treated KCNJ11 PNDM and five age, sex and body mass index-matched controls without diabetes had a high-carbohydrate and high-protein/fat meal on two separate mornings. …”
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45880
High-dose vitamin D3 to improve outcomes in the convalescent phase of complicated severe acute malnutrition in Pakistan: a double-blind randomised controlled trial (ViDiSAM)
Published 2025-03-01“…At 2-month follow-up, participants allocated to vitamin D had significantly higher mean serum 25(OH)D concentrations than those allocated to placebo (adjusted mean difference [aMD] 100.0 nmol/L, 95% confidence interval [CI] 72.2–127.8 nmol/L). …”
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