Local cerebral neurofilament light chain during acute stage is associated with clinical outcomes in stroke patients receiving endovascular thrombectomy by Kunxin Lin, Youliang Wang, Wenlong Zhao, Yiru Zheng, Xiaohua Sun, Ling Fang, Ying Fu, Ning Wang, Qianqian Lin

“…Compared with the lower level of local NfL, patients with higher local NfL were more likely male (74.5% vs. 54.5%, p = 0.017), had lower rate of intravenous thrombolysis (14.5% vs. 30.9%, p = 0.041), higher percentage of non-cardioembolic subtype (67.3% vs. 47.3%, p = 0.045). …”
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Nocturnal heart rate during sleep is associated with increased risk of type 2 diabetes mellitus in adults with obstructive sleep apnoea syndrome by Liping Wang, Jiajia Ran, Jingfeng Zou, Shaotian Li, Chunhui Tian, Xin Yang, Yiting Liu, Jingjing Wan, Wen Peng

“…HR was also classified into three groups, and the associations between different HR levels and T2DM risk were assessed using three logistic regression models.Results The mean age of the subjects was 54.49 (±9.95) years, and 374 subjects had T2DM. …”
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Segmental redistribution of myocardial blood flow after coronary sinus reducer implantation demonstrated by quantitative perfusion cardiovascular magnetic resonance by Kevin Cheng, Francisco Alpendurada, Chiara Bucciarelli-Ducci, Jose Almeida, Peter Kellman, Jonathan M. Hill, Dudley J. Pennell, Ranil de Silva

“…Results: A high proportion of myocardial segments had visually adjudicated ischemia at baseline (208 out of 254: 81.9%), which significantly reduced after CSR implantation (175 out of 254: 68.9%; P = 0.001). …”
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The Role of Rotational Thromboelastometry in Early Detection of the Hemostatic Derangements in Neonates with Systemic Candida Infection by Rozeta Sokou, Alexia Eleftheria Palioura, Aikaterini Konstantinidi, Alexandra Lianou, Maria Lampridou, Martha Theodoraki, Daniele Piovani, Stefanos Bonovas, Konstantina A. Tsante, Petros Ioannou, Nicoletta Iacovidou, Andreas G. Tsantes

“…Results: ROTEM parameters differed between neonates with SCI and healthy neonates, indicating a hypocoagulable profile of infected neonates. …”
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Integrative analysis of taurine metabolism-related genes prognostic signature with immunotherapy and identification of ABCB1 and GORASP1 as key genes in nasopharyngeal carcinoma by Zhang Feng, Yuhang Yang, Wenqi Luo, Jinqing Li, Zhenlian Xie, Long Zuo, Meijiao Duan, Dongzhi Zuo, Ruwei MO, Xuejing Tang, Shijiang Yi, Xiaosong He, Fangxian Liu, Ning Ma, Feng He

“…Molecular docking verified the interaction between these three core genes and taurine, which was further supported by single-cell sequencing showing significant expression variation among different cell clusters in NPC. We had elucidated the functions, therapeutic potential, and prognostic significance of three key genes related to taurine metabolism in NPC through multidimensional research and experimental validation. …”
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Metabolomics identify serum biomarkers for predicting acute exacerbation and severity of bronchiectasis by Jiaxin Yan, Fanxin Deng, Xueli Wang, Jing Wei, Yang Cao, Kaili Deng, Xiaolin Chen, Lei Shu, Lei Shi, Mingjing Wu, Ganzhu Feng

“…Compared to healthy controls, the abundance of 4-acetamidobutyric acid was elevated in the mild, moderate, and severe groups (p < 0.05), with no significant difference among the three groups. In the severe BE group, the abundances of taurochenodecoxycholic acid, oleamide, hexadecanamide, and glycodeoxycholic acid were significantly elevated from those in mild and moderate BE groups (p < 0.05), with Youden index (YI) ≥ 0.8 for all metabolites; the combination of these 4 metabolites had an area under the ROC curve (AUROC) of 0.99, a sensitivity of 100 % and a specificity of 93.3 % for identifying severe BE. …”
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Cost-effectiveness of PD-1 inhibitors combined with chemotherapy for first-line treatment of oesophageal squamous cell carcinoma in China: a comprehensive analysis by Kai Xu, Man Yu, Qingli Sun, Lingli Zhang, Xiaodan Qian, Dan Su, Jinhong Gong, Jingjing Shang, Yingtao Lin, Xin Li

“…Probabilistic analysis indicated that toripalimab, sintilimab, and tislelizumab had the highest probabilities of being cost-effective, at 83.1%, 81.4%, and 70.0%, respectively.Conclusion Sintilimab, toripalimab, and tislelizumab are the most cost-effective PD-1 inhibitors when combined with chemotherapy for the first-line treatment of advanced ESCC in China, with ICERs below the WTP threshold. …”
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Accessibility in online exhibitions of Brazilian science museums and centers: identifying strategies and barriers by Jessica Norberto Rocha, Jessica Norberto Rocha, Letícia Marinho, Letícia Marinho, Gabriela Heck, Gabriela Heck, Marcelle Pita de Sousa Carmo, Marcelle Pita de Sousa Carmo, Willian Vieira de Abreu, Willian Vieira de Abreu

“…The online exhibitions shared their content through various types of media, which necessitate different assistive resources and accessibility options. …”
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Deep infections after low-velocity ballistic tibia fractures are frequently polymicrobial and recalcitrant by Nainisha Chintalapudi, MD, Brianna R. Fram, MD, Susan Odum, PhD, Rachel B. Seymour, PhD, Madhav A. Karunakar, MD, EMIT, Joseph R. Hsu, MD, Laurence Kempton, MD, Kevin Phelps, MD, Stephen Sims, MD, Suman Medda, MD, Juliette Sweeney, BS, Kate Hickson, BS, Catherine Young, BS, Priyanka Kamath

“…The deep infection rate was 12% (16/134) with no significant difference in injury characteristics, index surgical characteristics, or time to antibiotics between the groups (P > 0.05). …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…In the mentioned towers, the variety of shapes and forms in the facade was present both in the facade itself and compared to other towers around, they had different and more varied shapes and forms. …”
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Prevalence of chronic obstructive pulmonary disease in high-risk populations at low, intermediate, high altitudes: a population based cross-sectional study in Yunnan Province, Chin... by Geyi Wen, Jinliang Meng, Huadan Wang, Puxian Peng, Yanyan Xu, Ruiqi Wang, Zhengmao Yan, Bangyan Du, Aihan Wen, Guohong Luo, Wenlong Cui, Songyuan Tang, Yunhui Zhang

“…COPD patients in high-risk populations at high-altitude areas had a higher prevalence of ethnic minorities and significant biomass fuel exposure. …”
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Impact of measurable residual disease clearance kinetics in patients with AML undergoing intensive chemotherapy by Wei-Ying Jen, Koji Sasaki, Farhad Ravandi, Tapan M. Kadia, Sa A. Wang, Wei Wang, Sanam Loghavi, Naval G. Daver, Courtney D. DiNardo, Ghayas C. Issa, Hussein A. Abbas, Cedric Nasnas, Alex Bataller, Samuel Urrutia, Omer S. Karrar, Sherry Pierce, Hagop M. Kantarjian, Nicholas J. Short

“…We retrospectively studied patients with newly diagnosed (ND) AML who achieved remission with frontline intensive chemotherapy and had MRD assessed by flow cytometry after induction (time point 1 [TP1]) and after cycles 2 or 3 (TP2). …”
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Efficacy and safety of hematopoietic stem cell transplantation vs. immunosuppressive therapy in patients with hepatitis-associated aplastic anemia: a systematic review and meta-ana... by Yaonan Hong, Qi Liu, Zhuonan Sun, Peicheng Wang, Xu Wang, Ziying Su, Yuzhu Li, Wenbin Liu, Huijin Hu, Yingying Shen, Baodong Ye, Yuhong Zhou, Shan Liu, Dijiong Wu

“…There was no significant difference in the overall response and one-year overall survival for each age group. …”
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Biocomposite Active Whey Protein Films with Thyme Reinforced by Electrospun Polylactic Acid Fiber Mat by Andreea (Lanciu) Dorofte, Iulia Bleoanca, Florentina Ionela Bucur, Gabriel Mustatea, Daniela Borda, Felicia Stan, Catalin Fetecau

“…The experimental results show that WF/G4 have a FTIR fingerprint resembling PLA, retained ~50% of the volatile compounds present in the uncovered film (WF/TEO), while it only had 1.41 ± 0.14 (%) of the permeability to octanol of the WF/G1 film. …”
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Bleeding resuscitation in the ambulance service, an observational study of standard care in Sweden by G. Skallsjö, G. Sandström, JG. Sato Folatre, AM. Harstad, A. Åström Victorén, E. Sömoen, E. Höglund, J. Haglund, J. Sköld, T. Bergström, C. Magnusson, K. Wibring, B. Romlin, A. Wikman

“…Ambulance organizations in six different regions were invited to participate, each of them for a period of six months. …”
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Seed Germination Responses to Temperature and Osmotic Stress Conditions in <i>Brachiaria</i> Forage Grasses by Francuois L. Müller, Jabulile E. Leroko, Clement F. Cupido, Igshaan Samuels, Nothando Ngcobo, Elizabeth L. Masemola, Fortune Manganyi-Valoyi, Tlou Julius Tjelele

“…This study aimed to determine the impacts of different temperature and moisture conditions on the seed germination characteristics of five <i>Brachiaria</i> genotypes. …”
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Integrating multi-omics to unveil PSMD12 as a critical gene in promoting brain metastases of lung adenocarcinoma by Xin Li, Juxuan Zhang, Meng Zhang, Wenbin Jiang, Dexin Jia, Ruxiong Wang, Hao Li, Zhihui Wang, Yixin Liu, Lefan Tang, Jiaxing Deng, Wenyuan Zhao, Yan Yu, Shilong Liu, Lishuang Qi

“…Immunohistochemical results confirmed that patients exhibiting high PSMD12 protein expression had a significantly higher incidence of BM within 5 years and shorter progression-free survival. …”
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Influence mechanism of natural factors and human socio-economic activities on ecosystem health in arid regions of Central Asia: A case study of Fuyun area, northwest China by Xu Bi, Kailong Shi, Yongyong Fu, Wangyue Zhou, Ruoning Zhao, Haijun Bao

“…Utilizing a deep learning-based Vigor-Organization-Resilience-Service (VORS) framework, this paper evaluated the spatio-temporal variation characteristics of the ecosystem health index (EHI) and its correlation with natural and human socio-economic factors across different elevation gradients in 2000, 2010, and 2020. …”
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Optimal protein requirement for rapid and coordinated test growth of juvenile sea urchin (Strongylocentrotus intermedius) by Panke Gong, Haijing Liu, Dan Gou, Weixiao Di, Huinan Zuo, Jun Ding, Yaqing Chang, Rantao Zuo

“…In this study, a 90-days satiety feeding experiment was performed to investigate the effects of different protein levels on the feed intake, somatic growth, and test characteristics of juvenile S. intermedius. …”
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Improving social determinants of health significantly reduces AIDS incidence: a modelling study of 1.17 million individuals in Brazil by Davide Rasella, James Macinko, Megan Naidoo, Rodrigo Volmir Rezende Anderle, Felipe Alves Rubio, Priscila Scaff, Ana Paula Santin Bertoni, José Alejandro Ordoñez, Iracema Lua, Gonzalo Barreix, Luis Eugenio de Souza, Maria Ines Costa Dourado

“…We compared them with an alternative scenario where the effect of inequalities in SDH was removed. The difference between scenarios and subpopulations was measured in terms of cumulative rate ratios (RR) and avoidable cases over the study period. …”
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