Physicochemical and textural properties of gummy candies prepared with fruit vinegar by Rita Székelyhidi, Zsolt Giczi, Roberta Pallag, Erika Lakatos, Beatrix Sik

“…In terms of the texture of the candies, the two candies prepared with different fruit vinegars had similar textural properties, however, in terms of hardness (3523.10 N/m2), gumminess (3266.25 N/m2), and chewiness (3425.33 N/m2) the gummy candy with apple cider vinegar proved to be better. …”
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SUDEP risk is influenced by longevity genomics: a polygenic risk score studyResearch in context by Helena Martins, James D. Mills, Susanna Pagni, Medine I. Gulcebi, Angeliki Vakrinou, Patrick B. Moloney, Lisa M. Clayton, Ravishankara Bellampalli, Hannah Stamberger, Sarah Weckhuysen, Pasquale Striano, Federico Zara, Richard D. Bagnall, Rebekah V. Harris, Kate M. Lawrence, Lynette G. Sadleir, Douglas E. Crompton, Daniel Friedman, Juliana Laze, Ling Li, Samuel F. Berkovic, Christopher Semsarian, Ingrid E. Scheffer, Orrin Devinsky, Karoline Kuchenbaecker, Simona Balestrini, Sanjay M. Sisodiya

“…Methods: Genetic data from people who had succumbed to SUDEP was compared to data from people with epilepsy who had not succumbed to SUDEP and from healthy controls. …”
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Short-, medium- and long-chain chlorinated paraffins from indoor/outdoor air in Guanzhong Plain, China: Characteristics, distribution and human exposure risks by Xiuqun Liu, Han Song, Jingzhi Wang, Xiaomei Huang, Li Xing, Xi Li, Ge Ma, Zhibao Dong, Yongming Han, Junji Cao

“…However, the CPs in gaseous phase and CPs in PM2.5 displayed different sources. Human exposure risk assessment indicated that the CPs had no significant risks to different age groups basing on the inhalation. …”
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OP-5 ACUTE-ON-CHRONIC LIVER FAILURE (ACLF) CRITERIA IN ALCOHOL-ASSOCIATED HEPATITIS: IMPLICATIONS FOR LIVER TRANSPLANTATION by LUIS ANTONIO DÍAZ PIGA, Paula Huerta, Renata Farias, Bastian Alcayaga, Francisco Idalsoaga, Gustavo Ayares, Jorge Arnold, María Ayala-Valverde, Diego Perez, Jaime Gomez, Rodrigo Escarate, Eduardo Fuentes-López, Katherine Maldonado, Juan Pablo Roblero, Daniela Simian, Blanca Norero, Raul Lazarte, José Antonio Velarde, Jacqueline Córdova, Fátima Higuera-de-la-Tijera, Alfredo Servin-Caamaño, Jesús Varela, Scherezada Mejía Loza, Rita Silva, Cristina Melo Rocha, Roberta C. Araujo, Gustavo Henrique Pereira, Claudia Alves Couto, Fernando Bessone, Mario Tanno, Gustavo Romero, Manuel Mendizabal, Sebastián Marciano, Gonzalo Gomez Perdiguero, Melisa Dirchwolf, Pedro Montes, Patricia Guerra Salazar, Geraldine Ramos, Susana Castro Sánchez, Juan Carlos Restrepo, Enrique Carrera, Mayur Brahmania, Ashwani K. Singal, Winston Dunn, Ramon Bataller, Vijay Shah, Patrick S. Kamath, Marco Arrese, Juan Pablo Arab

“…In the multivariable model adjusted by age, body mass index, and MELD score, individuals with ACLF grade 3 had lower survival than those without ACLF (HR 2.67, 95%CI: 1.50–4.76; p=0.001). …”
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Discovery of mammalian collagens I and III within ancient poriferan biopolymer spongin by Hermann Ehrlich, Ivan Miksik, Mikhail V. Tsurkan, Paul Simon, Filip Porzucek, Jakub Dalibor Rybka, Monika Mankowska, Roberta Galli, Christine Viehweger, Erica Brendler, Alona Voronkina, Martyna Pajewska-Szmyt, Aleksei Tabachnik, Konstantin R. Tabachnick, Carla Vogt, Marcin Wysokowski, Teofil Jesionowski, Tomasz Buchwald, Miroslaw Szybowicz, Kinga Skieresz-Szewczyk, Hanna Jackowiak, Alexander Ereskovsky, Amadeus C. S. de Alcântara, Alberto M. dos Santos, Clauber H. S. da Costa, Sofia E. Arevalo, Munir S. Skaf, Markus J. Buehler

“…Abstract Spongin is a fundamental biopolymer that has played a crucial role in the skeletogenesis of keratosan sponges for over 800 million years. This biomaterial had so far remained chemically unidentified and believed to be an enigmatic type of halogenated collagen-keratin-based bioelastomer. …”
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Analysis of epidemiology and nomogram construction for prediction and clinical decision-making in gliomas by Yuxin Zhao, Zihan Xu, Zihan Xu, Zihan Xu, Ying Liu, Ming Ye, Rui Chen, Zhongyu Cao, Hong Zhou, Yang Zhou

“…Additionally, the incidence of different histology varied significantly among different age groups. …”
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Comparison of somatic mutations and clinicopathologic features of micropapillary and non-micropapillary colorectal carcinomas by Zeynep Sagnak Yilmaz, Sibel Demir Kececi, Sevdegul Aydin Mungan, Ismail Saygin, Sulen Sarioglu

“…The mean age, T and N staging were significantly different between PIK3CA mutant and PIK3CA wild-type cases (p = 0.01; p = 0.033; p = 0.019, respectively). …”
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TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma by Harsh Nitin Dongre, Rammah Elnour, Stian Tornaas, Siren Fromreide, Liv Cecilie Vestrheim Thomsen, Ingrid Benedicte Moss Kolseth, Elisabeth Sivy Nginamau, Anne Christine Johannessen, Olav Karsten Vintermyr, Daniela Elena Costea, Line Bjørge

“…Results The results of p53 and p16INK4A immunohistochemistry confirmed three VSCC subtypes associated with different prognosis. The TP53 mutation status was identified as an independent prognostic factor of worse progression‐free survival (p = 0.024) after adjustment for FIGO stage. p16INK4A immunohistochemistry, mRNA ISH, and DNA PCR had excellent concordance in terms of HPV detection. …”
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Effectiveness of Biochar Biofertilizer on Some Morphological, Physiological and Biochemical Traits of Marigold (Calendula officinalis L.) Under Cadmium Stress by Mahyar Gerami, Leila Dustdar Mahmoudabad, Akram Ghorbanpour, Mohadeseh Amiri

“…Results and Discussion: The results showed that different concentrations of Cd decreased the wet and dry weights of roots and aerial parts of the plant. …”
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Genome-Wide Identification and Expression Analysis of the Mango (<i>Mangifera indica</i> L.) SWEET Gene Family by Lirong Zhou, Xinyu Liu, Xiangchi Leng, Meng Zhang, Zhuanying Yang, Wentian Xu, Songbiao Wang, Hongxia Wu, Qingzhi Liang

“…Meanwhile, the transcription levels of mango SWEET genes in different varieties and at different fruit development stages were also analyzed to obtain information about their functions. …”
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Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…Interventions to increase adherence across long-term conditions have had limited success, and it is not yet clear which strategies are most effective. …”
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Assessing seasonal and weather effects on depression and physical activity using mobile health data by Yuezhou Zhang, Amos A. Folarin, Yatharth Ranjan, Nicholas Cummins, Zulqarnain Rashid, Pauline Conde, Callum Stewart, Shaoxiong Sun, Srinivasan Vairavan, Faith Matcham, Carolin Oetzmann, Sara Siddi, Femke Lamers, Sara Simblett, Til Wykes, David C. Mohr, Josep Maria Haro, Brenda W. J. H. Penninx, Vaibhav A. Narayan, Matthew Hotopf, Richard J. B. Dobson, Abhishek Pratap, RADAR-CNS consortium

“…The subgroup with stable depression had older participants with lower baseline depression severity. …”
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Longitudinal Analyses and Predictive Factors of Radiation-Induced Lymphopenia After Postmastectomy Hypofractionated Radiation Therapy for Breast Cancer: A Pooled Cohort Study of 2... by Xu-Ran Zhao, MD, Hui Fang, MD, Hao Jing, MD, Qiu-Zi Zhong, MD, Hong-Fen Wu, MD, Xiao-Rong Hou, MD, Li-Hua Dong, MD, Ya-Hua Zhong, MD, Jing Jin, MD, Li-Na Zhao, MD, Xiao-Hong Wang, MD, Wei-Fang Yang, MD, Jian Tie, MD, Yu-Fei Lu, MD, Guang-Yi Sun, MD, Dan-Qiong Wang, MD, Yu Tang, MD, Shu-Nan Qi, MD, Yong-Wen Song, MD, Yue-Ping Liu, MD, Yuan Tang, MD, Ning-Ning Lu, MD, Bo Chen, MD, Wen-Wen Zhang, MD, Yi-Rui Zhai, MD, Shang-Ying Hu, Jun Zhang, MD, Ye-Xiong Li, MD, Na Zhang, MD, Shu-Lian Wang, MD

“…Univariate, multivariable linear regression and propensity score matching analyses were performed to evaluate the effect of different RT techniques on nadir PLC. Results: During RT, 121 (19.9%) patients had grade ≥3 RIL with a nadir PLC of 0.75 ± 0.33 × 109/L. …”
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Role of body anthropometry in severe asthmatic patients: Evidences from the Severe Asthma Network in Italy (SANI) registry by Erminia Ridolo, PhD, Martina Ottoni, MD, Francesca Nicoletta, MD, Francesca Locatelli, MD, Luigi Martinelli, MD, Matteo Maule, MD, Naila Arif Cheema, MD, Francesco Blasi, PhD, Pierluigi Paggiaro, MD, Enrico Heffler, PhD, Luisa Brussino, PhD, Giorgio Walter Canonica, MD, Gianenrico Senna, MD, Marco Caminati, MD, Diego Bagnasco, PhD, Cecilia Calabrese, PhD, Gianna Camiciottoli, MD, Giovanna Elisiana Carpagnano, PhD, Cristiano Caruso, MD, Angelo Guido Corsico, PhD, Maria Teresa Costantino, MD, Claudia Crimi, PhD, Alice D'Adda, MD, Simona D’Alò, MD, Maria D'Amato, PhD, Corrado D'Andria, MD, Stefano Del Giacco, MD, Fabiano Di Marco, PhD, Nicola Cosimo Facciolongo, MD, Alessandro Farsi, MD, Manuela Latorre, PhD, Manlio Milanese, PhD, Michele Mondoni, MD, Eustachio Nettis, MD, Girolamo Pelaia, MD, Laura Pini, MD, Luisa Ricciardi, PhD, Fabio Luigi Massimo Ricciardolo, PhD, Luca Richeldi, PhD, Pierachille Santus, PhD, Nicola Scichilone, PhD, Giulia Scioscia, PhD, Giuseppe Spadaro, MD, Antonio Spanevello, MD, Paolo Tarsia, MD, Mona Rita Yacoub, PhD

“…Obese asthmatics had lower blood eosinophilic count, and fractional exhaled nitric oxide (FeNO) levels than non-obese asthmatics. …”
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Durable T cell immunity to COVID-19 vaccines in MS patients on B cell depletion therapy by Julia Davis-Porada, Ceren Tozlu, Claudia Aiello, Sokratis A. Apostolidis, Amit Bar-Or, Riley Bove, Diego A. Espinoza, Sugeidy Ferreira Brito, Dina Jacobs, Mihir Kakara, Kaho Onomichi, Adelle Ricci, Joseph J. Sabatino, Elizabeth Walker, E. John Wherry, Lili Zhang, Wen Zhu, Zongqi Xia, Philip De Jager, Sarah Flanagan Wesley, Rebecca Straus Farber, Donna L. Farber

“…BCD-treated participants had significantly reduced antibody levels and enhanced frequencies of S-reactive CD4+ and CD8+ memory T cells to COVID-19 vaccination compared to the non-BCD group, with some variations among different BCD formulations. …”
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Development of antibacterial magnetic clay-based nanocomposites for water treatment by Horue, Manuel, Barraqué, Facundo, Montes, María Luciana, Zelaya-Soulé, María Emilia, Morantes, César Fernández, Urruchua, Florencia Camila, Correa, Hilda Edith, Castro, Guillermo Raul, Fernandez, Mariela Alejandra

“…The magnetic materials had a similar antimicrobial effect to those without magnetic properties, indicating that Fe oxides can be nucleated to impart a magnetic response without affecting the biocide properties. …”
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The Effectiveness of Trauma-Aware Parenting Intervention on Relationship between Attachment and Emotional Disturbance in Adoptive Families by Mehrana Mehrana, Mansoureh Bahramipour Isfahani

“…MethodsThe research method was semi-experimental with a pre-test, and post-test design and a 45-day follow-up period with a heterogeneous control group. This research had the ethics code number IR. IAU. KHUISF. REC.1402.338. …”
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Real-world effectiveness of novel hormonal agents and docetaxel in patients with prostate cancer: A head-to-head comparison by Yuanshi Jiao, Isaac Ho, Tunghiu Li, Rong Na, Chunka Wong, Jiaqi Wang, Steven Wai Kwan Siu, Yan Wei, Yingyao Chen, Esther W. Chan, Xue Li

“…Additionally, patients treated with NHAs had a significantly lower annual HRU during follow up. …”
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Integrative analyses of single‐cell and bulk RNA sequencing reveal tumour microenvironment features associated with neoadjuvant immunochemotherapy response in oesophageal squamous... by Xianxian Wu, Xiaoxing Ye, Wei Ji, Xiangyang Yu, Ahuan Xie, Zichang Xiang, Zhilin Sui, Jiquan Tang, Zhentao Yu

“…Finally, we described the different characteristics of malignant epithelial cells from different pathological responses to tumours. …”
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Evaluation of anesthesiology residents in the diagnosis and control of malignant hyperthermia: comparison of three scenarios of realistic simulation ‒ a cross-sectional controlled... by Mariana F.L. Neville, Victor Guimarães de Almeida, Pamela Vieira Andrade, Joilson Moura Santos, Masashi Munechika, David Ferez, Mary dos Santos Silva, Leonardo Ayres Canga, Ana Cristina Tripoloni, Thierry Girard, Helga Cristina Almeida da Silva

“…Conclusion: In a realistic high-fidelity MH simulation, the participants had satisfactory performance regarding technical and non-technical skills. …”
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