Establishing and Validating an Aging-Related Prognostic Signature in Osteosarcoma by Yibo Ma, Shuo Zheng, Mingjun Xu, Changjian Chen, Hongtao He

“…A nine-ARG-based signature in the TCGA cohort, including BMP8A, CORT, SLC17A9, VEGFA, GAL, SSX1, RASGRP2, SDC3, and EVI2B, has been created and developed and could well perform patient stratification into the high- and low-risk groups. …”
Get full text

Risk factors and prediction model of metabolic disorders in adult patients with pituitary stalk interruption syndrome by Deyue Jiang, Shengjie Wang, Yan Xiao, Peng Zhi, Erhan Zheng, Zhaohui Lyu, Qinghua Guo

“…An analysis was conducted on the clinical data of adult PSIS patients who visited the endocrinology department of the First Medical Center of the People’s Liberation Army General Hospital from January 2005 to August 2023. …”
Get full text

THE SEQUANCE OF THE DIAGNOSTIC PROCESS DURING THE INVESTIGATION OF THE MASSETER AND TEMPORALIS MUSCLES IN PATIENTS WITH INTACT DENTAL ROWS by Y. I. Semenenko, I. P. Semenenko, V. M. Dvornik, T. V. Polyschuk

“…The purpose of our work is to develop a diagnostic guideline to the study of the masseter and temporalis muscles in patients with intact dental rows to obtain reliable results of dentition status and comparison of the data in various pathological conditions. …”
Get full text

Implementation of a Program to Tackle Dental Caries in Schoolchildren in the State of São Paulo through Continuing Education by Amanda Iida Giraldes, Luana Camila Brisolla Ferreira, Ana Maria Cervato-Mancuso, Fernanda Campos de Almeida Carrer

“…This is a case report with a qualitative-quantitative approach. Data sources included document analysis and statistics produced by YouTube. …”
Get full text

Abnormal proportions and functions of myeloid-derived suppressor cells in peripheral blood of patients with diffuse large B-cell lymphoma by Jingru Liu, Shucheng Chen, Yanrong Huang, Kaiming Xu, Maoqing Tan, Wei Dai, Xiaoting Wang, Diyu Hou, Shuxia Zhang, Jiadi Chen, Huifang Huang

“…Using flow cytometry detected MDSCs and T cells proliferation, apoptosis, T cells activation and function in the co-culture groups. RNA transcriptome sequencing analysis was conducted on DLBCL-MDSCs and HDs-MDSCs. …”
Get full text

The association between blood metals and cardiovascular diseases: findings from National Health and Nutrition Examination Survey 2011–2020 by Bin Li, Haiyue Liu, Devrakshita Mishra, Zhen Yuan, Yizhi Zhang, Longzhen Zhang, Yanshu Huang, Ye Zhang, Ju Lin, Jianyou Chen, Zuheng Liu

“…Participants were divided into CVD (n = 2,676, 11.41%) and Non-CVD (N = 20,772, 88.59%) groups. A significant difference in the increased odds ratio of CVDs and higher blood Lead levels was found in the logistic analysis [OR (95% CI) = 13.545 (8.470–21.662) P < 0.001]. …”
Get full text

What factors are associated with informal carers’ psychological morbidity during end-of-life home care? A systematic review and thematic synthesis of observational quantitative stu... by Tracey Shield, Kerin Bayliss, Alexander Hodkinson, Maria Panagioti, Alison Wearden, Jackie Flynn, Christine Rowland, Penny Bee, Morag Farquhar, Danielle Harris, Gunn Grande

“…Newcastle–Ottawa Quality Assessment Scale was used. Thematic analysis with box score presentation, and meta-analysis were done where data permitted. …”
Get full text

Evaluating accountability, transparency, and bias in AI-assisted healthcare decision- making: a qualitative study of healthcare professionals’ perspectives in the UK by Saoudi CE Nouis, Victoria Uren, Srushti Jariwala

“…Forty participants—including clinicians, healthcare administrators, and AI developers—took part in semi-structured interviews or focus groups. …”
Get full text

Childhood triglyceride-glucose index and pre-hypertension in adulthood: a prospective cohort study by Lingli Zhao, Zhijie Cui, Jiahui Ouyang, Hua Qu, Hua Qu, Zhuye Gao, Zhuye Gao

“…Data on triglycerides (TG), fasting glucose (Fg), and low-density lipoprotein cholesterol (LDL-C) were collected from cross-sectional examinations of participants during childhood. …”
Get full text

Decoding the hypoxic tumor microenvironment in colorectal cancer for prognostic modeling and therapeutic target discovery by Xiao-Cui Duan, Yan Zhou, Fan Feng, Hai-Bo Jiang, Mei-Lin Wang, Zhe Han, Hong-Fei Pang, Yu-Hang Liu, Heng-Zhe Jia, Meng- He, Hong-Pan Xu, Yuan-Yuan Wang

“…Drug analysis highlighted associations of model genes with PI3K/MTOR and apoptosis pathways. …”
Get full text

Immunoglobulin G dynamics and outcomes of hypogammaglobulinemia in liver transplant recipients by Yongseop Lee, Eun-Ki Min, Jae In Kim, Jaeeun Seong, Deok-Gie Kim, Dong Jin Joo, Myoung Soo Kim, Jae Geun Lee, Su Jin Jeong

“…IgG levels before and after transplantation (1 month, 6 months, and 1 year) did not differ significantly between the groups. Overall, 36.0% of patients developed HGG within 1 year after transplantation. …”
Get full text

Assessment of Functional Capacity of Immune System in Patients with Multiple Sclerosis using QuantiFERON Monitor by Zbysek Pavelek, Ondrej Soucek, Jan Krejsek, Ilona Sejkorova, Oldrich Vysata, Blanka Klimová, Francesco Angelucci, Pavel Stourac, Martin Valis, Marek Peterka, Lukáš Sobisek, Michal Novotny

“…Plasmatic IFN-γ was measured using the ELISA kit for the QFM and data were obtained in IU/ml. Results. The results showed that controls had nearly 2-fold higher levels of IFN-γ (QFM score) in median (q25, q75) 228.00 (112.20, 358.67) than the MS patient groups: pMS 144.80 (31.23, 302.00); fMS 130.50 (39.95, 217.07) which is statistically significant difference P-value: HC vs. pMS = 0.0071; HC vs. fMS = 0.0468. …”
Get full text

The Attitude of Healthcare Workers to Safe use of Medical Instruments in a Training and Research Hospital by Filiz Özyiğit, Ayşegül Küçük, Özlem Altuntaş, İnci Arıkan, Hayat Kumbasar, Sibel Fener, Birgül Kahraman

“…Statistical analysis was performed using SPSS 21.0 and data were analyzed using the t-test and ANOVA. …”
Get full text

Adapting COVID-19 research infrastructure to capture influenza and respiratory syncytial virus alongside SARS-CoV-2 in UK healthcare workers winter 2022/23 and beyond: protocol for... by Victoria Hall, Susan Hopkins, Jonathan Broad, Naomi Platt, Dominic Sparkes, Sarah Foulkes, Anna Howells, Michelle Cole, Jameel Khawam, Conall Watson, Nick Andrews

“…UK devolved administrations were supported to develop local protocols. Analysis plans include incidence of asymptomatic and symptomatic infection, comparisons of vaccination coverage, assessment of sick day burden, and effectiveness of seasonal influenza against infection and time off work. …”
Get full text

Blockchain technology and power asymmetries in Tanzanian agricultural supply chains by Deo Shao, Roselyne Alphonce, Fredrick Ishengoma, Hilda Mwangakala, Frederick Chali, Cesilia Mambile, Abiud Bongole, Hector Mongi, Bernard Julius, Aliko Matola

“…The results help policymakers develop targeted interventions to enable smallholders, women, and other disadvantaged groups to access and adopt technologies. …”
Get full text

CURRENT ASPECTS OF ETIOTROPIC COVID-19 THERAPY by D. N. Zemskov, L. A. Balykova, O. A. Radaeva, K. Ya. Zaslavskaya, P. A. Bely, E. V. Semenova, M. V. Shirmankina, K. N. Koryanova

“…The search for new effective and safe etiotropic drugs for the treatment of COVID-19, as well as the collection and analysis of post-registration data on the drugs already used in clinical practice, continues.…”
Get full text

Novel non-curable resection prediction model for early colorectal cancer following endoscopic submucosal dissection based on inflammatory immune index by Xiunan Li, Lei Zhang, Biao Xu, Shu Ding, Jing Wang, Jing Wang, Yu Jia

“…We sought to explore the predictive ability of SII for non-curative resection of early colorectal cancer treated with ESD, and to establish a related predictive model.MethodsA retrospective analysis was performed on data from patients with early-stage colorectal cancer who underwent ESD in our hospital between January 2019 and December 2022. …”
Get full text

Associations between metal exposure and metabolic syndrome: exploring the mediating role of biological ageing among US adults by Liuyan Zheng, Xinyue Lu, Suping Luo, Jianhui Guo, Xingyan Xu, Le Yang, Mingjun Chen, Shaowei Lin, Xiaoxu Xie, Huangyuan Li, Siying Wu

“…Methods This study utilized National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2018 and included 11,541 adults aged 20 years and above. …”
Get full text

Comparison of four MRI diffusion models to differentiate benign from metastatic retropharyngeal lymph nodes by Jun Liu, Li Hua, Fei Wang, Ming Chen, Yinan Sun, Zhi Hu, Luqing Shu, Andong He, Mengxiao Liu, Qing Yang, Juan Zhu, Yinfeng Qian

“…Logistic regression analysis was performed to identify the best diffusion indicator for classification and to develop a multiparameter model combining morphological features. …”
Get full text

Mitochondrial DNA control region polymorphisms in Dongxiang blue-eggshell chicken and their evolutionary relatedness with nine domestic Wugu breeds by Zhang Xuedong, Li Qinghai, Zhang Chengxian, Chen Xianhui, Lou Lifeng, Wang Huanhuan

“…The aim of the present study was to analyze mtDNA control region polymorphisms and evolution in conservative groups of Dongxiang blue-eggshell chickens in comparison to other domestic Wugu breeds to better elucidate the genetic structure of Dongxiang chickens to further develop conservation and exploitation programs.Blood samples were collected from 39 (19 cocks and 20 hens) eleventh generation Dongxiang blue-eggshell conservative chickens and DNA was extracted and then PCR-amplified and the products were sequenced. …”
Get full text