Camrelizumab-based therapies for the treatment of advanced lung cancer: a prospective, open-label, multicenter, observational, real-world study by Dong Zhao, Minghong Bi, Xiaofei Cheng, Shuhong Wang, Huaidong Cheng, Xiaoyang Xia, Huan Chen, Yanbei Zhang, Zhiqiang Hu, Qisheng Cao, Hui Liang, Fan Wang, Xuhong Min, Ling Xu, Kehai Feng, Jinhua Zhou, Xinzhong Li, Rui Wang, Hua Xie, Xiaosi Chen, Kangsheng Gu

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Emergency volunteering willingness and participation: a cross-sectional survey of residents in northern China by Hong Sun, Chaojie Liu, Wei Xu, Ye Li, Qunhong Wu, Lijun Gao, Zheng Kang, Yanhua Hao, Ning Ning, Mingli Jiao, Libo Liang, Yu Cui, Mengli Shi, Chao Liang, Xiaowen Zhao, Jie Fei, Qiuyu Wei, Ming Yi

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Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing by Jingyuan Huo, Zhen Wang, Wenting Zhao, Miao Chen, Haoyang Li, Fengpu He, Xiao Tian, Yaqi Ma, Firyuza Husanova, Liang Ma, Yiming Ni, Hongda Ding, Weidong Li, Hongfei Xu

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Roadmap on specialty optical fibers by Mário F S Ferreira, Mohd Rehan, Vishwatosh Mishra, Shailendra Kumar Varshney, Francesco Poletti, Nguyen Phuoc Trung Hoa, Weichao Wang, Qinyuan Zhang, Wenyu Du, Benli Yu, Zhijia Hu, Xian Feng, Jindan Shi, Anjali, Sunil Kumar, Michal Kamrádek, Mukul Chandra Paul, Kazi Abedin, Bertrand Kibler, Frédéric Smektala, Xiushan Zhu, Andrey Pryamikov, Stephan Reitzenstein

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Influence of Educational Films on Antiviral Prescription for COVID-19: Insights from Web-Based Survey in Japan by Kosaku Komiya, Akihiko Hagiwara, Yuichiro Shindo, Kazufumi Takamatsu, Naoki Nishimura, Yukako Takechi, Eiki Ichihara, Takahiro Takazono, Shinyu Izumi, Shimpei Gotoh, Seiichiro Sakao, Takehiro Izumo, Kazuko Yamamoto, Kazuhiro Yatera, Hiroshi Kakeya, Yoko Shibata, Keisuke Tomii, Hironori Sagara, Yuka Sasaki, Toyohiro Hirai, Akihito Yokoyama, Hiroshi Mukae, Takashi Ogura

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Chronic Myeloid Leukemia Patient Registry in the Russian Federation: From Observational Studies to the Efficacy Evaluation in Clinical Practice by AG Turkina, NV Novitskaya, AK Golenkov, VA Shuvaev, LI Napso, V Krylova, AM Savrilova, GSh Safuanova, AV Korobkin, TYu Klitochenko, EV Burnasheva, EV Vasil’ev, OM Senderova, EYu Fedorova, LM Yalunina, EK Nekhai, GB Kuchma, AS Lyamkina, NG Shchedrova

“…Due to the significant increase in life expectancy and the quality of life in patients with chronic myeloid leukemia (CML) as well as the growing need for expensive tyrosine kinase inhibitors (TKI), the analysis of cost-effectiveness and lifelong monitoring of patients is especially important. …”
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Independent validation and outlier analysis of EuroPOND Alzheimer’s disease staging model using ADNI and real-world clinical data by Mandy M. J. Wittens, Diana M. Sima, Arne Brys, Hanne Struyfs, Ellis Niemantsverdriet, Ellen De Roeck, Christine Bastin, Florence Benoit, Bruno Bergmans, Jean-Christophe Bier, Peter Paul de Deyn, Olivier Deryck, Bernard Hanseeuw, Adrian Ivanoiu, Gaëtane Picard, Eric Salmon, Kurt Segers, Anne Sieben, Evert Thiery, Jos Tournoy, Anne-Marie van Binst, Jan Versijpt, Dirk Smeets, Maria Bjerke, Maura Bellio, Neil P. Oxtoby, Daniel C. Alexander, Annemie Ribbens, Sebastiaan Engelborghs

“…The naMCI and aMCI groups were compared by EBM stage proportions, and the model’s effectiveness at patient level was evaluated. Results The research cohort’s maximum likelihood event sequence comprised CSF Aβ1-42, P-tau181, T-tau, RAVLT, MMSE, and cortical volumes. …”
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Comparison of Perioperative Outcomes of Holmium Laser Enucleation of the Prostate for Standard (≤149 ml) Versus Very Large (≥150 ml) Prostate Glands: Retrospective Analysis of a Pr... by Jacob Schmidt, Jorien Krediet, Holger Beutel, Ayoub Hidayat Allah, Nella Gagel, Isabel Lichy, Bernhard Ralla, Maha Ullmann, Robert Peters, Frank Friedersdorff, Martin Kanne

“…We found that while the surgery is generally effective for very large prostates, it takes longer and has a higher risk of complications in comparison to more typical prostate sizes. …”
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Insight into rifampicin resistance behind discordant mutations in RpoB of Mycobacterium tuberculosis: A molecular dynamics simulations study by Muhammad Tahir Khan, Elise Dumont, Jialou Zhu, Kashif Iqbal Sahibzada, Madeeha Shahzad Lodhi, Mehmood Qadir, Dongqing Wei

“…In this study, we aimed to find the effects of discordant mutations on RNA polymerase (RNAP) β-subunit (RpoB) thermodynamic properties leading RIF resistance. …”
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Drug-resistant pulmonary tuberculosis with surgical treatment: clinical forms, histological and macroscopic aspects by L.M. Zahaba, M.S. Opanasenko, I.V. Liskina, O.V. Tereshkovych, O.O. Melnyk, B.M. Konik, M.I. Kalenychenko, A.O. Kozykina, V.I. Lysenko, L.I. Levanda

“…In cases of pre-extensively drug-resistant tuberculosis, the development of more severe forms of lung tuberculosis and the lower preoperative effectiveness of specific anti-tuberculosis therapy was observed.…”
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Prevention of extubation failure in neurocritical care patients with residual disorder of consciousness: the Brain-Injured Patients Extubation Readiness (BIPER) study protocol for... by Emmanuel Futier, Bruno Pereira, Russell Chabanne, Elodie Caumon, Dominique Morand, Audrey De Jong, Jean-Michel Constantin, Matthieu Jabaudon, Thomas Godet, Benjamin Andanson, Pierre Borrel, Leo Astier, Nathalie Bourguignon, Lise Laclautre

“…Consequently, extubation failure is more frequent than in general ICU patients, and there is no clear evidence-based clinical trigger for extubation. …”
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Attractive targeted sugar baits for malaria control in western Kenya (ATSB-Kenya): enrolment characteristics of cohort children and households by Alice Kamau, Kizito Obiet, Caroline Ogwang, Daniel P. McDermott, Maia Lesosky, Julia Janssen, Wycliffe Odongo, Julie R. Gutman, Jonathan S. Schultz, Wycliffe Nicholas, Brian Seda, Mercy Chepkirui, Frank Aduwo, Oliver Towett, Kephas Otieno, Martin J. Donnelly, Eric Ochomo, Simon Kariuki, Aaron M. Samuels, Feiko O. ter Kuile, Sarah G. Staedke

“…Additional tools are needed to effectively control malaria in this area. Trial registration The ATSB trial is registered under Clinicaltrials.gov NCT05219565…”
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Treatments of transarterial chemoembolization (TACE), stereotactic body radiotherapy (SBRT) and immunotherapy reshape the systemic tumor immune environment (STIE) in patients with... by Cai-Ning Zhao, Chi-Leung Chiang, Wan-Hang Keith Chiu, Sik-Kwan Kenneth Chan, Chun-Bong James Li, Wei-Wei Chen, Dan-Yang Zheng, Wen-Qi Chen, Ren Ji, Chung-Mau Lo, Salma K. Jabbour, Chi-Yan Albert Chan, Feng-Ming (Spring) Kong

“…Peripheral blood samples were collected at baseline and after TACE, SBRT, and IO for T-lymphocyte subtyping by flow cytometry. Generalized estimation equation was employed for longitudinal analyses. …”
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Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensusResearch in context by Teferi Mekonnen, Leanne Staniford, Spencer Connell, Zofia Das-Gupta, Umanga DeSilva, Yasmine Saoud, Isabel Miller, Mohapradeep Mohan, Simon Nienhuijs, Megha Poddar, Vaishali Chetan Deshmukh, Marli Conradie-Smit, Soo Huat Teoh, Sanjeev Sockalingam, Emilia Huvinen, Paolo Sbraccia, Ronald Liem, Michael Vallis, Kenneth Clare, Tracy Zvenyach, Karen Coulman, Marianela Aguirre Ackermann, Verónica Vázquez-Velázquez, Yudith Preiss Contreras, Josep Vidal, Agbo Urudinachi, María Fernanda Tejeda-Muñoz, Ian Patton, T Alafia Samuels, Morgan Emile Gabriel Salmon Leguede, Georgia Rigas, Ximena Ramos Salas, Michael Crotty, Bruno Halpern, Daniel Bessesen, Laura Pizzi, Omniyat Mohammed Al Hajeri, Arya M. Sharma

“…Despite the availability of multimodal treatments, there is a lack of standardised, patient-centred outcome measures to effectively assess and improve clinical care. This project aimed to define a core set of standardised outcome measures for adults with obesity, incorporating both patient-reported and clinician-reported outcomes. …”
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The improvement path of depression and anxiety among adult women in Shanxi Province, China: a fuzzy-set qualitative comparative analysis by Dahong Wu, Dahong Wu, Dahong Wu, Guangxian Zeng, Guangxian Zeng, Guangxian Zeng, Jing Cheng, Jing Cheng, Jing Cheng, Jie Liu, Jie Liu, Jie Liu, Sitian Li, Sitian Li, Sitian Li, Mengxia Qin, Mengxia Qin, Mengxia Qin, Lu He, Lu He, Lu He, Qilong Feng

“…Age exhibited marginal protective effects for both conditions (OR = 0.99, 95% CI = 0.98–1.00). …”
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Health literacy assessment and analysis of influencing factors in pregnant women with gestational diabetes mellitus in Southwest China by Fangmei Tang, Fangmei Tang, Li Gu, Li Gu, Xiujing Guo, Xiujing Guo, Wenjing Fu, Wenjing Fu, Benyi He, Yuqing Song, Yuqing Song, Dehua Li, Dehua Li

“…The Maternal and child health information access questionnaire, Chinese version of the HLS-14, Perceived Social Support Scale (PSSS) and General Self-efficacy Scale (GSES) was used to collect health information access behaviors, health literacy, social support and self-efficacy levels, respectively. …”
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Comparison of proximal femoral universal nail and proximal femoral nail anti-rotation internal fixation for older patients with intertrochanteric femoral fracture: a retrospective... by Yuan Cao, Yuan Cao, Jixing Fan, Jixing Fan, Zengzhen Cui, Zengzhen Cui, Youliang Hao, Youliang Hao, Shengtao Lai, Shengtao Lai, Yun Tian, Yun Tian, Yang Lv, Yang Lv, Fang Zhou, Fang Zhou

“…In the AO/OTA classification of 31-A3 stratification, the Harris score and PPMS score of the PFUN group during the postoperative follow-up period were higher than those of the PFNA group (p < 0.05).ConclusionThe PFUN is an effective and safe internal fixation device for IFFs, especially for unstable medial and lateral wall fractures. …”
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Germline prediction of immune checkpoint inhibitor discontinuation for immune-related adverse events by Min Li, Geoffrey Liu, Elad Ziv, Rohit Thummalapalli, Adam Schoenfeld, Melinda C Aldrich, Scott Huntsman, Zoe Quandt, Christine M Lovly, Pooja Middha, Karmugi Balaratnam, Eduardo Cardenas, Christina J Falcon, Princess Margaret Lung Group, Matthew A Gubens, Khaleeq Khan, Devalben Patel, Luna Jia Zhan

“…We used a published polygenic risk score for autoimmune diseases (PRSAD) in the general population and validated it in the All of Us. …”
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應用智慧型家教系統於國小學童閱讀策略 教學之學習歷程研究 A Study on the Learning Process of Applying an Autotutoring System to Teach Reading Strategies to Elementary School Children... by 陳茹玲 Ju-Ling Chen, 曾厚強 Hou-Chiang Tseng, 連啟舜 Chi-Shun Lien, 蔡旻穎 Min-Ying Tsai, 宋曜廷 Yao-Ting Sung

“…Conclusion In conclusion, this study highlights the effectiveness of autotutor systems in supporting learning, analyzing students’ learning paths, and identifying differences in strategy use. …”
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Historical overview, advancements, and future prospects of coalfield structure research in China by Daiyong CAO, Yiwen JU, Yucheng XIA, Bo JIANG, Shuzheng NING, Yingchun WEI, Anmin WANG, Xiaoming LI, Wenfeng ZHAN, Huantong LI, Lu WANG, Zhuocheng CAI

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