Remdesivir Use in Pediatric Patients with Acute SARS-CoV-2 Infection Is Safe and Well Tolerated by Delma J. Nieves, M. Tuan Tran, Jasjit Singh, Negar Ashouri, Tricia Morphew, Jennifer G. Lusk, Felice C. Adler-Shohet, Rachel Marano, Stephanie Osborne, Jennifer Strickland, Antonio C. Arrieta

“…Demographics and underlying conditions were reported as averages; for laboratory values, linear regression was applied within a generalized linear mixed-effects model framework to evaluate the significance of changes in average levels over time. …”
Get full text

Investigation and Trend Prediction of Disease Burden of Hypertensionin the Elderly Population Globally and in China from 1990 to 2021 by ZHAO Xiaoxiao, LU Xiaohui, KE Lixin, GAO Wulin, MENG Xiangran, REN Lili, DING Yunhan, ZHANG Qiang, XUN Yangqin, WU Jibiao, LU Cuncun

“…Furthermore, the burden of hypertension was generally higher among elderly males than females in China. …”
Get full text

Differences in elementary-age children’s accelerometer - measured physical activity between school and summer: three-year findings from the What’s UP (Undermining Prevention) with... by Michael W. Beets, Sarah Burkart, Christopher Pfledderer, Elizabeth Adams, R. Glenn Weaver, Bridget Armstrong, Keith Brazendale, Xuanxuan Zhu, Alexander McLain, Brie Turner-McGrievy, Russell Pate, Andrew Kaczynski, Amanda Fairchild, Brian Saelens, Hannah Parker

“…Accumulation of MVPA was consistently greater during school compared to summer across ages and income groups. Generally, the difference between school and summer widened with increasing age, except for girls from middle-income households. …”
Get full text

Associations between dietary diversity and self-rated health in a transverse study of four local food systems (French Guiana, Guadeloupe, Portugal and Senegal) by Michael Rapinski, Richard Raymond, Damien Davy, Jean-Philippe Bedell, Abdou Ka, Jean Lubszynski, Pascal Jean Lopez, Eduardo Ferreira Da Silva, Nathalie El Deghel, Enguerran Macia, Priscilla Duboz

“…Public health messaging should continue to promote dietary diversity and home-cooked meals as effective strategies for improving health. Self-rated health could serve as a useful tool for quickly assessing the outcomes of nutrition therapy.…”
Get full text

Machine learning model for random forest acute oral toxicity prediction by A.M. Elsayad, M.M. Zeghid, K.A. Elsayad, A.N. Khan, ِA.K.M. Baareh, A. Sadiq, S.A. Mukhtar, H.F. Ali, S. Abd El-kader

“…A surrogate decision tree developed from random forests predictions reached an area under the curve of 0.929.CONCLUSION: Random forest models effectively predicted acute oral toxicity, particularly when addressing class imbalance through cost-sensitive learning and resampling. leveraging explainable artificial intelligence techniques, including permutation feature importance, surrogate decision tree analysis and local interpretable model-agnostic explanations, this study identified key molecular descriptors driving toxicity. …”
Get full text

Mental health problems and associated factors of students at different learning stages during and after COVID-19 pandemic in Sichuan, China by Jia Cai, Yu Wang, Cong Wang, Zhong-Yue Deng, Yun-Fei Mu, Ai-Ping Deng, Hong-Jun Song, Yi Huang, Ding-Zhi Fang, Ge-Lin Liu, Yan Hu, Xin Yang, Bin-Zhi Zhang, Wei Zhang, Mao-Sheng Ran

“…This study aimed to explore the long-term effects of COVID-19 on students’ mental health at different learning stage and provide recommendations on education and health policies after the lifting of COVID-19 constrictions. …”
Get full text

Significant associations between high-risk sexual behaviors and enterotypes of gut microbiome in HIV-negative men who have sex with men by Kangjie Li, Xinjing Liu, Xiaohua Zhong, Haijiao Zeng, Tian Liu, Bing Lin, Pinyi Chen, Biao Xie, Xiaoni Zhong

“…ABSTRACT Gut microbiome of men who have sex with men (MSM) exhibits distinctive characteristics compared with general populations. The dysbiosis of the gut microbiome in MSM is also associated with the onset and evolution of HIV infection. …”
Get full text

Men who have sex with men perceiving that sex with women carries the greatest risk of HIV acquisition: results from a mixed‐methods systematic review in sub‐Saharan Africa by Marion Fiorentino, Marie Dos Santos, August Eubanks, Nathan Yanwou, Christian Laurent, Perrine Roux, Bruno Spire

“…Underestimation by MSM of their HIV acquisition risk with male partners can pose significant barriers to effective HIV preventive behaviours and strengthen the transmission risk from MSM to their female partners. …”
Get full text

Transanal total mesorectal excision vs intersphincteric resection for low rectal cancer: a propensity-score matching study by Li Zhengbiao, Feng Qingbo, Wang Xingqin, Xu Fujian, Wang Qi, Huang Yong, Xie Ming

“…[Objectives] To compare the clinical effectiveness between transanal total mesorectal excision (taTME) and intersphincteric resection (ISR) for low rectal cancer. …”
Get full text

Unique thermal architecture integrating heliostat solar fields with a dual-loop power generation cycle employing thermoelectric; thermal/financial study and GA optimization by Amr S. Abouzied, Xiaoming Guo, Azher M. Abed, Mohammed A. Alghassab, Fahad M. Alhomayani, Baseem Khan, Yasser Elmasry, Ahmad Almadhor, Salem Alkhalaf, Albara Ibrahim Alrawashdeh

Get full text

Efficacy and associated factors of endoscopic transpapillary drainage for postoperative biliary leakage by Jun Murata, Minoru Shigekawa, Shuji Ishii, Takahiro Suda, Kenji Ikezawa, Motohiro Hirao, Kengo Matsumoto, Tadashi Kegasawa, Kiyoshi Iwahashi, Sadaharu Iio, Fumihiko Nakanishi, Shoichi Nakazuru, Yuichi Yoshida, Takuo Yamai, Katsuhiko Sato, Teppei Yoshioka, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara

Get full text

Healthcare professionals' perceptions of system preparedness during public health emergencies: a path analysis of mental health impacts by Runze Huang, Runze Huang, Xueting Ding, Anlong Li, Anlong Li, Guodong Nie, Guodong Nie, Ling Cheng, Yajing Li, Yajing Li, Wei Gao, Han Ge, Han Ge, Mingjun Zhang, Huaidong Cheng, Huaidong Cheng, Huaidong Cheng

Get full text

Recycling of nickel metal from spent nickel-manganese-cobalt (NMC) cathode batteries using H3PO4–H2C2O4 solution combination as an efficient leaching agent by Adyatma Bhagaskara, Dita Adi Saputra, Aldino Javier Saviola, Karna Wijaya, Won-Chun Oh, Sri Rahayu, Muhammad Dikdik Gumelar, Aghni Ulma Saudi, Agustanhakri Agustanhakri, Abdul Hamid Budiman, Surat Indrijarso

Get full text

Anti-EGFR re-challenge with chemotherapy in RAS wild-type advanced colorectal cancer (A-REPEAT study): efficacy and correlations with tissue and plasma genotyping by J. Sgouros, A. Eliades, K. Papadopoulou, N. Korfiatis, D. Papamichael, E. Fountzilas, E. Tsolaki, A. Achilleos, K. Tsangaras, C. Loizides, G. Oikonomopoulos, T. Makatsoris, E. Kypri, M. Ioannides, G. Koumbaris, G. Fountzilas, P.C. Patsalis, G. Pentheroudakis

Get full text

Tumor copy-number alterations predict response to immune-checkpoint-blockade in gastrointestinal cancer by Lin Shen, Huan Chen, Ming Lu, Shuang Li, Henghui Zhang, Jifang Gong, Zhihao Lu, Zhi Peng, Xi Jiao, Lihong Wu, Wenbo Han, Jianling Zou, Jianing Yu, Huaibo Sun

Get full text

Carvacrol attenuates mucosal barrier impairment and tumorigenesis by regulating gut microbiome by Yating Fan, Ye Chen, Hua Yang, Na Chen, Xiangshuai Gu, Xiaoliang Feng, Chao Fang, Yuan Yin, Hongxin Deng, Lei Dai

Get full text

Lipid metabolism of apoptotic vesicles accelerates cutaneous wound healing by modulating macrophage function by Yuan Qin, Xin Chen, Lili Bao, Lili Ren, Geng Dou, Jianing Lian, Shujuan Xing, Zihan Li, Feng Ding, Wen Qin, Xulin Liu, Bin Zhu, Shiyu Liu, Zuolin Jin, Xiaoshan Yang

Get full text

Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD by Yulei Li, Peipei Liu, Tianjiao Hao, Sheng Liu, Xi Wang, Yufeng Xie, Ke Xu, Wenwen Lei, Cheng Zhang, Pu Han, Ying Li, Xiyue Jin, Yu Huan, Yafei Lu, Rong Zhang, Xiaoyan Li, Xin Zhao, Kun Xu, Pu Liao, Xuancheng Lu, Yuhai Bi, Hao Song, Guizhen Wu, Baoli Zhu, George F. Gao

Get full text

Transperineal laser ablation of the prostate as a treatment for benign prostatic hyperplasia and prostate cancer: The results of a Delphi consensus project by Andrea Cocci, Marta Pezzoli, Fernando Bianco, Franco Blefari, Pierluigi Bove, Francois Cornud, Gaetano De Rienzo, Paolo Destefanis, Danilo Di Trapani, Alessandro Giacobbe, Luca Giovanessi, Antonino Laganà, Giovanni Lughezzani, Guglielmo Manenti, Gianluca Muto, Gianluigi Patelli, Novello Pinzi, Stefano Regusci, Giorgio I. Russo, Juan I.M. Salamanca, Matteo Salvi, Luigi Silvestri, Fabrizio Verweij, Eric Walser, Riccardo G. Bertolo, Valerio Iacovelli, Alessandro Bertaccini, Debora Marchiori, Hugo Davila, Pasquale Ditonno, Paolo Gontero, Gennaro Iapicca, Theo M De Reijke, Vito Ricapito, Pierluca Pellegrini, Andrea Minervini, Sergio Serni, Francesco Sessa

Get full text

Lateral Spacing of TiO₂ Nanotube Coatings Modulates In Vivo Early New Bone Formation by Andreea Mariana Negrescu, Iuliana Ionascu, Madalina Georgiana Necula, Niculae Tudor, Maksim Kamaleev, Otilia Zarnescu, Anca Mazare, Patrik Schmuki, Anisoara Cimpean

Get full text