Organ donation under V-A ECMO support: insights and recommendations from Japan’s first two cases by Futoshi Nagashima, Daisaku Matsui, Takashi Hazama, Korehito Takasu, Tomoya Matsuda, Tomoaki Nakai, Naru Kageyama, Tomohiro Oda, Junko Nagata, Eriko Sugie, Yuki Yamaoka

Get full text

Assessing junior doctors’ preparedness in inpatient cardiac arrest management: a cross-sectional study at a university hospital by Muhammad Azmi Bin Sukor, Dazlin Masdiana binti Sabardin

“…Abstract Background Cardiac arrest is an emergency that requires immediate and effective intervention. Junior doctors, who are often the first responders, play an important role in the initial management of in-hospital cardiac arrest (IHCA). …”
Get full text

Association between the 2012 Health and Social Care Act and specialist visits and hospitalisations in England: A controlled interrupted time series analysis. by James A Lopez Bernal, Christine Y Lu, Antonio Gasparrini, Steven Cummins, J Frank Wharam, Steven B Soumerai

“…It gave control of £67 billion of the NHS budget for secondary care to general practitioner (GP) led Clinical Commissioning Groups (CCGs). …”
Get full text

Knowledge Attitude and Practices of Mothers on Management of Malnutrition Among Children Under Five Years in Bugongi Town Council, Sheema District. by Mwiine, Dickens Richard

“…The study findings revealed that the biggest proportion of the sampled mothers had attained some level of education. From the general understanding levels of education have effects on the care a mother gives a child. …”
Get full text

Knowledge Attitude and Practices of Mothers on Management of Malnutrion Among Children Under Five Years in Bugongi Town Council, Sheema District. by Mwiine, Dickens Richard

“…The study findings revealed that the biggest proportion of the sampled mothers had attained some level of education. From the general understanding levels of education have effects on the care a mother gives a child. …”
Get full text

TREATMENT OF BLAST PHASE MYELOPROLIFERATIVE NEOPLASM WITH THE COMBINATION OF AZACITIDINE, VENETOCLAX AND RUXOLITINIB by Fidan Khalilova, Azer Kerimov, Gulnar Kerimova

“…Conclusion: The use of the AZA+VEN protocol was effective in BP-MF. The subsequent addition of RUX to the treatment further increased the effectiveness of the treatment and led to an improvement in the patient's general condition and a decrease in complaints.…”
Get full text

Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom by Yun MA, Siyuan HE

“…This research aims to explore the institutional motivations, potential challenges, and optimization paths of the spatial planning concept of “gap”, focusing on how these gaps impact the effectiveness of protection and regional development. …”
Get full text

Case Reports: The core of practice-based evidence by Antonio Villa

“…Case reports are particularly useful to: 1) recognize rare or uncommon clinical presentation of common diseases or clinical features of rare illnesses; 2) identify new diseases; and 3) establish the cost-effectiveness of medical treatments [2]. Furthermore, a case report is often the most important source of information on adverse effects following therapies. …”
Get full text

Multi-scenario Dynamic Simulation and Optimization of Urban Ventilation Environment: A Case Study of Taiyuan Metropolitan Area by Junda HUANG, Yuncai WANG

“…Urban ventilation, as an important way to deliver fresh and cold air to built-up areas, can effectively improve the comfort level. Although many international scholars have researched the optimization of urban ventilation, the existing research in China mainly focuses on the measurement of the current urban ventilation environment, while neglecting the long-term dynamic changes of the urban ventilation environment in response to different planning objectives in the process of urban development.MethodsThis research proposes a research framework generally applicable to the simulation of future changes in ventilation environment within city – region systems for the first time. …”
Get full text

A Novel Digital Intervention to Facilitate Diabetes Self-Management Among People with Schizophrenia and Related Disorders: Development and Acceptability Testing of SMART by Arnautovska U, Ritchie G, Soole R, Menon A, Korman N, Milton A, Varnfield M, Kelly JT, Jansen PM, Baker A, Ireland D, Russell AW, Chapman J, Mulligan K, Hirani SP, Vitangcol KJ, McKeon G, Siskind D

“…Antipsychotic drugs significantly contribute to this risk through metabolic adverse effects, including weight gain and insulin resistance. …”
Get full text

Comparison of polygenic risk scores for type 2 diabetes developed from different ancestry groups by Takuma Furukawa, Megumi Hara, Yuichiro Nishida, Keitaro Tanaka, Chisato Shimanoe, Chiharu Iwasaka, Jun Otonari, Hiroaki Ikezaki, Mako Nagayoshi, Takashi Tamura, Yudai Tamada, Rieko Okada, Isao Oze, Hidemi Ito, Nobuaki Michihata, Yohko Nakamura, Shiroh Tanoue, Chihaya Koriyama, Sadao Suzuki, Takahiro Otani, Isao Watanabe, Satomi Tomida, Kiyonori Kuriki, Naoyuki Takashima, Aya Kadota, Masashi Ishizu, Takeshi Watanabe, Masahiro Nakatochi, Yukihide Momozawa, Kenji Wakai, Keitaro Matsuo, for the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group

Get full text

Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation by Pedro Vicente, Lara R. Inocêncio, Asier Ullate‐Agote, Ana F. Louro, João Jacinto, Beatriz Gamelas, Olalla Iglesias‐García, Patxi San Martin‐Uriz, Paula Aguirre‐Ruiz, Gonzalo R. Ríos‐Muñoz, María Eugenia Fernández‐Santos, Alain vanMil, Joost P. G. Sluijter, Felipe Prósper, Manuel M Mazo Vega, Paula M. Alves, Margarida Serra

Get full text

Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…Surgical treatment of GERD is more effective in patients was typical manifestations and positive treatment response to PPIs. …”
Get full text

Matrix metalloproteinases and heat shock proteins on extracellular vesicles in colorectal cancer patients: association with metabolic status by N. V. Yunusova, D. A. Svarovsky, E. E. Dandarova, D. N. Kostromitsky, A. A. Dimcha, O. V. Cheremisina, S. G. Afanasiev, A. I. Konovalov, Z. A. Startseva, I. V. Kondakova, M. R. Patysheva, A. E. Grigor'eva, L. V. Spirina

“…Comparison of protein expression on CD9- and FABP-4 positive vesicles will be useful to explain some clinical issues, such as the effectiveness of thermoradiotherapy or radiotherapy in obese CRC patients; for a more substantiated search for vesicular prognostic markers in obese cancer patients. …”
Get full text

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis by Li Lu, Jiewen Liao, Chao Xu, Yuan Xiong, Juan Zhou, Guangji Wang, Ze Lin, Kangkang Zha, Chuanlu Lin, Ruiyin Zeng, Guandong Dai, Qian Feng, Bobin Mi, Guohui Liu

Get full text

Intestinal Insights: The Gut Microbiome’s Role in Atherosclerotic Disease: A Narrative Review by Luana Alexandrescu, Adrian Paul Suceveanu, Alina Mihaela Stanigut, Doina Ecaterina Tofolean, Ani Docu Axelerad, Ionut Eduard Iordache, Alexandra Herlo, Andreea Nelson Twakor, Alina Doina Nicoara, Cristina Tocia, Andrei Dumitru, Eugen Dumitru, Laura Maria Condur, Cristian Florentin Aftenie, Ioan Tiberiu Tofolean

Get full text

Sustainable forest management: success and challenges in Ethiopia by Rusha Begna Wakweya

“…To achieve the goals of REDD+, including climate change mitigation, biodiversity enhancement, and improved rural livelihoods, effective forest governance is essential. Key success in SFM in Ethiopia. …”
Get full text

Developing a framework to measure the impact of large-scale land investment on sustainable development and to combat land grabbing in Africa: the case of Amhara region, Ethiopia by Assefa Mulaw, Gebeyehu Shibeshi

“…However, standard evaluation systems are required in the developing world in general and in Africa in particular, where the impacts of large-scale land-based investment are highly contested. …”
Get full text

Sputum colour charts to guide antibiotic self-treatment of acute exacerbation of chronic obstructive pulmonary disease: the Colour-COPD RCT by Eleni Gkini, Rachel L Adams, Daniella Spittle, Paul Ellis, Katherine Allsopp, Sanya Saleem, Matthew McKenna, Nick le Mesurier, Nicola Gale, Sarah Tearne, Peymane Adab, Rachel E Jordan, Nawar Diar Bakerly, Alice M Turner

“…Only half of acute exacerbation of chronic obstructive pulmonary disease are caused by bacterial infection, but self-management plans generally advocate use of antibiotics and steroids for all events, hence antibiotics may be overused. …”
Get full text

Leveraging Local Community Capacities for Sustainable Security: A Case Study of the Border Villages in Darmiyan and Sarbisheh Counties by Javad Mikaniki

“…While political and party solidarity had the lowest average among the variables, the average for all variables was still above 3.5, indicating that the different aspects of cohesion and solidarity were seen as contributing to sustainable security in the studied area.Hypothesis 1: Collaborative capacities in the studied area have been highly effective in achieving sustainable security.The observed ratio in the second group was much higher than the first group and the p-value supported the researcher's hypothesis that the participation capacities within the rural community had been highly effective in achieving sustainable security.Hypothesis 2: Social trust in the study area has been highly effective in achieving stable security.The observed ratio in the second group was much higher than the first group and the p-value confirmed the researcher's hypothesis that the social trust component within the rural community had been highly effective in achieving stable security.Hypothesis 3: The cohesion and solidarity of the local community has been very effective in achieving sustainable security.The observed ratio in the second group was much higher than the first group and the p-value supported the researcher's hypothesis that social cohesion and solidarity within the rural community had been highly effective in achieving sustainable security. …”
Get full text