HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation by Xu-Zhe Yu, Wei-Li Zhu, Hua-Chun Qian, Chun-Jiang Sun

“…BackgroundPapillary thyroid carcinoma (PTC) is the most common subtype of thyroid cancer and has shown a rising incidence globally. Despite its generally favorable prognosis, recurrence and therapeutic resistance remain challenges in clinical management. …”
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Affects for stress reaction and hemodynamics by multimodal opioid free anesthesia on patients with video-assisted thoracoscopic surgery by WU Meichao, YANG Fangfang, CAI Ning, MA Xingjun

“…Methods A total of 110 patients who underwent thoracoscopic bullectomy or lobectomy under general anesthesia at Fuyang People’s Hospital from January to October 2023 were randomly divided into OA group (n=55) and OFA group (n=55). …”
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A Mixed-Methods Usability Pilot of a Value-Goal Elicitation Tool in the Inpatient Setting for Older Adults Anticipating Post-Acute Care by Kirstin M. Piazza PhD, MSHP, RN, Caroline Pascal MPH, Syama R. Patel MPH, Caroline Sefcik MPH, Marilyn M. Schapira MD, MPH, Caroline Madrigal PhD, RN, Katherine C. Ritchey DO, MPH, Longyi Yip BSN, Aanand D. Naik MD, Robert E. Burke MD, MS

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Efficacy of tacrolimus or cyclophosphamide combined with glucocorticoids in the treatment of idiopathic membranous nephropathy by MAO Wen-li, DU Lin-na, ZHANG Zhen-zhen, LV Chen-xiao, CUI Mei-yu

“…Objective To observe the clinical efficacy and safety of tacrolimus(TAC)or cyclophosphamide(CTX)combined with glucocorticoids in treatment of idiopathic membranous nephropathy.Methods A retrospective study was conducted on46 patients who had been diagnosed as idiopathic membranous nephropathy from September 2016 to September 2017 in Qianfoshan Hospital of Shandong Province.The patients were followed up for 36 weeks.The patients were divided into two groups.Twenty-seven patients were given TAC combined with glucocorticoid as experimental group.The 24-h urinary protein,serum albumin,serum creatinine,fasting blood glucose,triglyceride,total cholesterol levels and the rate of remission were recorded before and 4,8,12,24,and 36 weeks after treatment.The difference in the efficacy be-tween the two groups was compared.Results There were no significant differences in general data(gender,age,course of illness)and laboratory tests before treatment between the two groups(P>0.05).After 36 weeks of treatment,16 cases(59.25%)obtained complete remission in the experimental group and7 cases(36.84%)in the control group.The complete remission rate in the experimental group was significantly higher than that in the control group(P<0.01).Eight cases(29.63%)in the experimental group,and8 cases(42.11%)in the control group obtained partial remission.Three cases had ineffective efficacy in the experimental group(11.11%),and 4 cases(21.05%)in the control group.The 24-h urinary protein quantification was significantly reduced in the two groups after treatment as compared with that before treatment(P<0.05).The 24-h urinary protein quantification in the experimental group was decreased from(10.1±3.2)g to(1.2±2.6)g(P<0.01),and that in the control group was decreased from(8.6±3.8)g to(1.7±2.7)g(P<0.01),with the difference being very statistically significant.The serum albumin level was also significantly higher after treatment in both two group than that before treatment.The serum albumin level in the experimental group was increased from(22.3±3.6)g/L to(43.0±3.3)g/L(P<0.01),and from(23.5±4.5)g/L to(40.9±6.1)g/L in the control group(P<0.01),with the difference being statistically significant.There was no significant change in serum creatinine,blood glucose,triglyceride,total cholesterol during the treatment in both groups before and after treatment(P>0.05).During the course of treatment,no serious adverse reactions such as myelosuppression occurred in both groups.Conclusions TAC combined with glucocorticoid is effective and safe in the treatment of idiopathic membranous nephropathy.As compared with CTX,TAC can rapidly reduce 24-h urine protein quantification.…”
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Prevalence and clinical implications of occult hepatitis C infection: a meta-analysis of studies conducted in Egypt by Ahmed Azzam, Heba Khaled, Sarah Mohamed Hussein, Kyrillos R. Gendy, Fatma E. Hassan

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SLAP Trial: Shock Wave Lithotripsy and Mechanical Percussion Therapy Post ESWL for Renal Calculi by Nishal Patel, Adrian Roe, Donna Stanton, Jay Roberts, Akshay Kothari

“…This study has shown that MPI can be effectively performed in a home setting without the need for medical supervision and results in improved stone clearance rates post ESWL. …”
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Publishing Identifiable Patient Photographs in the Digital Age: Focus Group Study of Patients, Doctors, and Medical Students by Marija Roguljić, Dina Šimunović, Ivan Buljan, Marija Franka Žuljević, Antonela Turić, Ana Marušić

“…All stakeholder groups expressed a lack of knowledge about online publishing in general and concerns about the fate of patient photographs in the digital environment after publication. …”
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circ_0002346 Suppresses Non-Small-Cell Lung Cancer Progression Depending on the Regulation of the miR-582-3p/STXBP6 Axis by Weijie Wang, Yi Lin, Guanghui Zhang, Guofu Shi, Yongsheng Jiang, Wentao Hu, Wei Zuo

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Avaliação dos níveis de ruído, luz e calor em máquinas de colheita florestal Evaluation of noise, light and heat levels of forest harvesting machines by Luciano J. Minette, Emília P. da Silva, Amaury P. de Souza, Kátia R. Silva

“…The forest loader and the mini-skidder showed poor lighting and the indexes of effective temperature were outside the thermal comfort zone for all machines. …”
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Sleep quality and associated factors among adult patients with epilepsy attending follow-up care at referral hospitals in Amhara region, Ethiopia. by Sintayehu Simie Tsega, Birhaneselassie Gebeyehu Yazew, Kennean Mekonnen

“…These findings highlight improving medication adherence and social support are effective strategies to improve the sleep quality of epileptic patients. …”
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Prophylaxis of herpetic infections reactivation before the planned pregnancy by V. S. Kopcha, I. V. Lipkovska, N. H. Shpikula

“…The aim of the work – to estimate serum and molecular-genetic markers of chronic CMV-, HSV1- and HSV2-infection reactivation, that can result in the prenatal pathology, and also to offer the effective medicamentous prophylaxis of these herpetic infections at the stage of pregnancy planning. …”
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Why People with Overweight and Obesity Are Seeking Care Through Digital Obesity Services: A Qualitative Analysis of Patients from Australia’s Largest Digital Obesity Provider by Louis Talay, Matt Vickers, Sarah Loftus

“…Although modern weight-loss medications have demonstrated unprecedented effectiveness in clinical trials, they should only be prescribed under strict safety guidelines and used as a supplement to lifestyle therapy. …”
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Economic damage associated with excess salt intake of Russian people in 2016 by Yu. A. Balanova, A. V. Kontsevaya, A. O. Myrzamatova, D. K. Mukaneeva, M. B. Khudyakov

“…In the structure of the ED of each nosology, excess salt intake cause from 4,5% (CVD in general) to 17% (for T2D) and 16,1% (stroke) of the entire damage.Conclusion. …”
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Comparison of the Efficacy of Polyvinyl Alcohol Colorless Embolic Microspheres (8Spheres) and Gelatin Embolic Microspheres (Embosphere) in Uterine Artery Embolization for Symptomat... by Gao S, Li F, Song F, Zhang X, Wang Y, Wang J

“…We collected preoperative general conditions, menstrual status, and uterine and fibroid sizes as indicated by magnetic resonance imaging, as well as changes in ovarian hormone levels before and 6 months after the procedure. …”
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Epidemiology of Horsepox. The New Aspects by L. F. Stovba, A. A. Petrov, S. A. Melnikov, O. V. Chukhralia, N. K. Cherniкova, S. V. Borisevich

“…It cannot be ruled out that the use of modern genetic engineering technologies may lead not only to the development of effective vaccines, but also to the production of new orthopoxviruses pathogenic for humans and animals, or to the reintroduction of smallpox, which is especially dangerous in the context of the virtual absence of smallpox immunity in the population and international control over experiments in the synthetic biology of dangerous pathogens.…”
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Prevalence of alcohol use disorders and associated factors among people with epilepsy attending Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia by Waja T, Ebrahim J, Yohannis Z, Bedaso A

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Telehealth Interventions in Pharmacy Practice: Systematic Review of Reviews and Recommendations by Rachel Lai Kay Chong, Andrew Siang Ee Chan, Crystal Min Siu Chua, Yi Feng Lai

“…The use of telehealth in pharmacy has generally seen an improvement in overall outcomes compared to traditional pharmacy practice. …”
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The relief supplies of the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) during the Israel–Hamas War, 2023 by Dr Soichi Takeishi

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Connected and Automated Vehicle Trajectory Control in Stochastic Heterogeneous Traffic Flow with Human-Driven Vehicles Under Communication Delay and Disturbances by Meiqi Liu, Yang Chen, Ruochen Hao

“…The results show that the proposed <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>H</mi><mo>∞</mo></msub></semantics></math></inline-formula> controller is robust and effective in stabilizing disturbances in the stochastically heterogeneous traffic flow and is scalable to arbitrary sub-platoons in various CAV penetration rates in the heterogeneous traffic flow of road vehicles. …”
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Models of symmetric three-layer waveguide structures with graded-index core and nonlinear optical liners by S. E. Savotchenko

“…The solutions obtained describe in general terms the transverse distribution of the amplitude of the electric field envelope. …”
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