Radical hemithorax radiotherapy induces an increase in circulating PD-1+ T lymphocytes and in the soluble levels of PD-L1 in malignant pleural mesothelioma patients: a possible syn... by Alberto Revelant, Francesca Gessoni, Marcella Montico, Raja Dhibi, Giulia Brisotto, Mariateresa Casarotto, Martina Zanchetta, Veronica Paduano, Filippo Sperti, Chiara Evangelista, Fabiana Giordari, Valli De Re, Marco Trovò, Emilio Minatel, Maurizio Mascarin, Agostino Steffan, Elena Muraro

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Developments in the study of the role of lactate metabolism in the genesis and progression of thyroid cancer by Lei Shi, Lei Shi, Lei Shi, Xuyang Zhong, Jiafeng Liu, Yong Ying, Zibing Liao, Jin Liu, Liwen Zhao, Jianing Zhong, Jianing Zhong, Xiangtai Zeng, Xiangtai Zeng

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Canadian Recommendations for Germline Genetic Testing of Patients with Breast Cancer: A Call to Action by Evan Weber, Carlos A. Carmona-Gonzalez, Melanie Boucher, Andrea Eisen, Kara Laing, Jennifer Melvin, Kasmintan A. Schrader, Sandeep Sehdev, Stephanie M. Wong, Karen A. Gelmon

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Acute nonspecific (musculoskeletal) low back pain Guidelines of the Russian Society for the Study of Pain (RSSP) by V. A. Parfenov, N. N. Yakhno, M. L. Kukushkin, M. V. Churyukanov, O. S. Davydov, V. A. Golovacheva, A. I. Isaikin, E. E. Achkasov, G. Yu. Evzikov, A. E. Karateev, F. A. Khabirov, V. A. Shirokov

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Lactose intolerance awareness among adults in Riyadh, Saudi Arabia by Nouran Aleyeidi, Latifah Albeheiri, Fatimah Alrashed, Abeer Alangari, Atha Alghazi, Jinan Alzaid, Nariman Sheikh, Renad Alqahtani, Sarah Alajmi, Tafe Albogami

“…The aim of study was to assess the awareness of lactose intolerance and its associated factors among the general population of Riyadh City, Saudi Arabia. The prevalence of lactose intolerance in the study population was also assessed. …”
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Next-generation sequencing-based population genetics unravels the evolutionary history of Rhodomyrtus tomentosa in China by Xing-ming Xu, Bo-yong Liao, Su-jiao Liao, Qiao-mei Qin, Chun-yan He, Xin Ding, Wei Wu, Long-yuan Wang, Fang-qiu Zhang, Li-xia Peng, Bryan T. Drew, Yong-quan Li

“…Niche analysis revealed that the ice ages caused habitat contraction for the species, and populations with higher genetic diversity are generally distributed in areas with more suitable habitats. …”
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Salivary periostin levels as a non-invasive biomarker and their clinical correlates among healthy and periodontitis patients—a cross-sectional analytical study by Priyanka Padalkar, Sunaina Shetty Yadadi, Gopinath Vivekanandan, Shishir Ram Shetty, Mangesh Andhare, Aditi Pashine, Vineet Vinay, Vijay Desai, Vijay Desai, Raghavendra M. Shetty, Raghavendra M. Shetty, Raghavendra M. Shetty

“…The biomarker periostin is effective for evaluating both healthy and diseased periodontium.…”
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MRI-derived articular cartilage strains predict patient-reported outcomes six months post anterior cruciate ligament reconstruction by Emily Y. Miller, Woowon Lee, Timothy Lowe, Hongtian Zhu, Pablo F. Argote, Danielle Dresdner, James Kelly, Rachel M. Frank, Eric McCarty, Jonathan Bravman, Daniel Stokes, Nancy C. Emery, Corey P. Neu

“…The relationships between patient-reported outcome scores and all MRI metrics were quantified using general linear mixed-effects models and a combined best-fit multicontrast MRI model was then developed. …”
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An international, cross-sectional survey of preprint attitudes among biomedical researchers [version 2; peer review: 1 approved, 2 approved with reservations] by Valerie Chow, Lucas J. Santoro, Jeremy Y. Ng, David Moher, Kelly D. Cobey, Anna Catharina Vieira Armond, Sanam Ebrahimzadeh Pirshahid

“…This may be due to the general lack of peer review of preprints and little enthusiasm from external organizations such as journals, funding agencies, and universities. …”
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Deep Learning-based Identification of CP1 and CP2 Stars from LAMOST DR11 by ZhiWei Lu, Xiaoming Kong, YaTao Zhang, ZhenPing Yi, Meng Liu

“…We further analyzed the stellar parameters of CP stars. The effective temperature ( T _eff ) of CP1 stars ranges from 6000 K to 9000 K, peaking at 7500 K, while CP2 stars span 6000 K to 13,000 K, with peaks near 8900 K and 11,900 K. …”
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Barriers and drivers to COVID-19 protective behaviours of forcibly displaced myanmar nationals (FDMN)/ rohingya refugees in Cox's bazar, Bangladesh: A scoping review by Sarah Reda, Zarah Yusuf, Basel Karo, Balwinder Singh Chawla, Andreas Jansen, Saskia Lange, Jorge Martinez, Emily Dorothee Meyer, Julia Neufeind, Aarti Shrikrishana Singh, Elisa Wulkotte, Cath Jackson

“…Addressing the above-mentioned evidence gaps would assist future development of effective targeted interventions, tailored to the needs of specific population groups.…”
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The Role of Endoscopy in the Postoperative Management of Patients Treated for Esophageal Atresia: 20 Years of Experience by Francesco Grasso, Fabio Baldanza, Sara Pernicone, Marco Pensabene, Maria Sergio, Maria Rita Di Pace

“…<b>Conclusions</b>: Esophagogastroscopy is a safe and effective tool for diagnosing and managing complications after EA repair in infants. …”
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Life quality of the Russian population by the data from ESSE-RF study by A. V. Kontsevaya, S. A. Shalnova, Yu. A. Balanova, A. D. Deev, M. V. Sherashova, S. A. Boytsov, I. A. Trubacheva, D. V. Duplyakov, D. S. Kaskaeva, E. N. Shmatova, A. A. Kosinova, R. R. Ruf, A. I. Aristov, V. A. Metelskaya, R. G. Oganov, E. I. Suvorova, M. B. Khudyakov, Yu. V. Zhernakova, E. V. Oshchepkova, A. O. Konradi, O. P. Rotar, E. I. Baranova, N. V. Kulakova, V. A. Nevzorova, N. V. Shestakova, M. V. Mokshina, L. V. Rodionova, G. V. Tolparov, A. A. Shabunova, R. A. Kasimov, K. N. Kalashnikov, O. N. Kalachikova, O. A. Kondakova, A. V. Popov, N. A. Ustinova, E. V. Chumachek, A. A. Ledyaeva, G. I. Furmenko, O. A. Belova, S. V. Romanchuk, O. A. Nazarova, E. A. Shutemova, O. L. Barbarash, G. V. Artamonova, E. V. Indukaeva, T. A. Mulerova, S. A. Maksimov, A. E. Skripchenko, N. V. Cherkass, M. V. Tabakaev, Ya. V. Danilchenko, Yu. I. Grinshtein, M. M. Petrova, L. K. Danilova, A. A. Evsyukov, N. V. Topol'skaja, V. V. Shabalin, I. V. Medvedeva, M. A. Storozhok, V. N. Serebryakova, R. S. Karpov, A. Yu. Efanov, V. S. Kaveshnikov, A. V. Kapustina, S. E. Evstifeeva, G. A. Muromtseva, M. N. Mamedov, A. E. Imaeva, N. V. Gomyranova, V. V. Konstantinov

“…Life quality (LQ) is an integrated parameter of the health, applied for integral characterization of population health, and as the parameter of healthcare interventions effectiveness.Aim. To assess LQ in Russian population at the age 25-64 y. o. in general and in various socio-economical groups using EQ-5D, by the results of ESSE-RF (2012-2013) study.Material and methods. …”
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In Vivo Antimicrobial Activity of Nisin Z Against <i>S. aureus</i> and Polyurea Pharmadendrimer PURE_G4OEI₄₈ Against <i>P. aeruginosa</i> from Diabetic Foot In... by Isa Serrano, Dalila Mil-Homens, Rita F. Pires, Vasco D. B. Bonifácio, Joana F. Guerreiro, Eva Cunha, Sofia S. Costa, Luís Tavares, Manuela Oliveira

“…Nisin Z may have reduced the antibacterial effectiveness of both PURE_G4OEI₄₈ and amlodipine. …”
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And then there were many: insights from the tangled taxonomy of the Antarctic brittle star Ophioplinthus gelida (Echinodermata: Ophiuroidea) by Chester J. Sands, Chester J. Sands, Timothy D. O’Hara, Alice Guzzi, Alice Guzzi, Alice Guzzi, William P. Goodall-Copestake, William P. Goodall-Copestake, Peter Convey, Peter Convey, Peter Convey, Peter Convey, Bhavani E. Narayanaswamy, Rafael Martín-Ledo, Sabine Stöhr

“…To effectively manage biological assemblages, a sound knowledge of the biodiversity is essential. …”
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Organisational factors associated with burnout among emergency and internal medicine physicians: a qualitative study by Andrea Townson, Nadia Khan, Peter Dodek, Diane Lacaille, Lawrence Chow, Heather A Leitch, Anita Palepu, Amy Salmon, Farhad Ghaseminejad, Kira Rich, Debbie Rosenbaum, Emilia Rydz, Vishal Varshney, Elizabeth Stanger

“…Leveraging protective factors and intervening on organisational factors attributed to burnout such as improving communication and enhancing support services may be effective in addressing the physician burnout epidemic.…”
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Lower limb lymphoedema-related mental depression: A systematic review and meta-analysis of non-cancer-related studies by Tegene Atamenta Kitaw, Addisu Getie, Solomon Gebremichael Asgedom, Molalign Aligaz Adisu, Befkad Derese Tilahun, Alemu Birara Zemariam, Addis Wondmagegn Alamaw, Abebe Merchaw Faris, Tesfaye Engdaw Habtie, Melesse Abiye Munie, Eyob Shitie Lake, Gizachew Yilak, Mulat Ayele, Molla Azmeraw, Biruk Beletew Abate, Ribka Nigatu Haile

“…A weighted inverse variance random-effects model was used for pooled estimates, along with subgroup analysis, heterogeneity assessment, publication bias testing, and sensitivity analysis. …”
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Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-Cλ interface by John D. Bagert, Vaheh Oganesyan, Chi-I Chiang, Mike Iannotti, Jia Lin, Chunning Yang, Sterling Payne, Will McMahon, Samuel Edwards, Andrew Dippel, Mark Hutchinson, Fengying Huang, Vineela Aleti, Chendi Niu, Chen Qian, Jessica Denham, Sofia Ferreira, Pallab Pradhan, Mark Penney, Chunlei Wang, Wenhai Liu, Even Walseng, Yariv Mazor

“…While highly effective in promoting cognate heavy and light chain pairing, residual chain mispairing could be detected for specific combinations of Fv pairs. …”
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SAHELI:  Study and Action on Hysterectomy: Evidence on women’s health through the life course in India.  Protocol for a mixed-methods study [version 2; peer review: 2 approved] by Archana Kumari, Josyula K Lakshmi, Neerja Bhatla, Gita D Mishra, Dipti Govil, Sapna Desai, Hemali Heidi Sinha, Devaki Nambiar, Kranti Vora, Archana Roy

“…India has recently introduced national guidelines to address early hysterectomy, but large evidence gaps on the causes and consequences remain – which in turn limits the potential effectiveness of interventions at the clinical, health system and community level. …”
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Medication Adherence and Glycemic Control in Older Adults with Type 2 Diabetes: A Cross-Sectional Study in a Community Setting by Tânia Nascimento, Amanda Andrade, Ezequiel Pinto, Catarina Cabrita, Sandra Pais, Rocío de la Puerta

“…Medication adherence directly influences therapeutic effectiveness, making its assessment in clinical practice crucial. …”
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