Developing a pediatric emergency medicine simulation-based learning curriculum in Nepal by Morgan Bowling, Samantha Langer, Christine Saracino, Roshana Shrestha, Anish Joshi, Jared Kutzin, Christopher Strother, Darlene R. House

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Integrating Artificial Intelligence in urban redesign: A collaborative approach to post-war design phases by I. Alshafei, R. Almashhour

“…Traditional techniques for gathering data, allocating resources, and engaging the community have many challenges that negatively affect the effectiveness of re-designing and re-design measures. …”
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CLINIC, DIAGNOSIS AND EFFICIENCY OF NONINVASIVE METHOD OF TREATMENT YOUNG CHILDREN WITH HAEMORRHOIDS by А. Хамраєв, Ф. Файзуллаєв

“…For children of preschool age the most effective non-invasive method of treatment is rectal balonocompression. 3. …”
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Comprehensive Insights into the Economic Burden of Rheumatoid Arthritis in Latin America: A Systematic Literature Review of Regional Perspectives by Maldonado-Restrepo AI, Acelas-Gonzalez GE, Rodríguez-Vargas GS, Rodriguez-Linares P, Gonzalez-Rodriguez JL, Rojas-Villarraga A, Santos-Moreno P

“…Most economic studies focused on cost analysis (86%), while cost-effectiveness studies and cost-utility studies represented 7.4% and 3.3%, respectively. …”
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A CDKN2B-Associated Immune Prognostic Model for Predicting Immune Cell Infiltration and Prognosis in Esophageal Carcinoma by Peng X, Han J, Huang J, Zhou L, Chen X, Zhou W

“…We also a constructed an immune prognostic model (IPM) based on these genes. Thereafter, the effects of IPM on the immune microenvironment of EC were analyzed. …”
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Current status of the immunogenicity of enzyme replacement therapy in fabry disease by Jorge F. Gómez-Cerezo, Julián Fernández-Martín, Miguel Ángel Barba-Romero, Rosario Sánchez-Martínez, Alvaro Hermida-Ameijeiras, Maria Camprodon-Gómez, Saida Ortolano, Mónica A. Lopez-Rodriguez

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Survival prognostic nomogram for young metastatic non-small cell lung cancer: a study of the US SEER database and a Chinese cohort by Yu Li, Lei Cao, Yawen Ding, Lei Liu, Yonggang Zhu, Feng Cao

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Trait Mindfulness, Resilience, Self-Efficacy, and Postpartum Depression: A Dominance Analysis and Serial-Multiple Mediation Model by Mei X, Mei R, Li Y, Yang F, Liang M, Chen Q, Ye Z

“…Postpartum women in the mild group exhibited higher postpartum depressive symptoms than those in the moderate and high groups. The effects of trait mindfulness on postpartum depression were significantly mediated by resilience (B=− 0.064, 95% CI − 0.088 to − 0.044), self-efficacy (B=− 0.014, 95% CI − 0.023 to − 0.006), and serial mediation between resilience and self-efficacy (B=− 0.027, 95% CI − 0.040 to − 0.015). …”
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Ecosystem health evaluation and driving Force analysis of high groundwater Table Coal-Grain complex area based on remote sensing information by Anya Zhong, Zhenqi Hu, Tiantian Yang, Zhen Wang

“…Based on Landsat series data, with a focus on the compounded effects of soil salinization, landscape fragmentation, and air pollution on the degradation of ecosystems in mining regions with HGT. …”
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Strengthening health system's capacity for pre-exposure prophylaxis for adolescent girls and young women and adolescent boys and young men in South Africa (SHeS'Cap-PrEP): Protocol... by Edward Nicol, Trisha Ramraj, Mbuzeleni Hlongwa, Wisdom Basera, Ngcwalisa Jama, Carl Lombard, Tracy McClinton-Appollis, Darshini Govindasamy, Desiree Pass, Noluntu Funani, Sarah Aheron, Ariana Paredes-Vincent, Jennifer Drummond, Mireille Cheyip, Sibongile Dladla, Jason Bedford, Cathy Mathews

“…<h4>Introduction</h4>Pre-exposure prophylaxis (PrEP) is an effective prevention intervention that can be used to control HIV incidence especially among people who are at increased risk for HIV such as adolescent girls and young women (AGYW) and adolescent boys and young men (ABYM). …”
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Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial by Walter Staiano, Christine Callahan, Michelle Davis, Leah Tanner, Chelsea Coe, Sarah Kunkle, Ulrich Kirk

“…ConclusionsThe Headspace Sleep Program is an effective intervention for improving sleep disturbances in adults with clinical insomnia. …”
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Lynching and its Representation in African American Drama: Traumatic Memory in Sleep Deprivation Chamber and Rachel by Somayeh Salehi, Esmaeil Najar, Fazel Asadi Amjad

“…Psychological and emotional effects of lynching resembling permanent burns inscribed both on black bodies and black minds are reflected in Rachel's traumatized mind colliding with many rising conflicts in a white supremacist society that eventually leads to her total abandonment of sexual life and motherhood. …”
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EXPERIENCE OF USING THE PERPLEXITY AI-POWERED ANSWERING SYSTEM FOR EDUCA- TIONAL CONTENT GENERATION by Kateryna Osadcha, Maryna Osadcha

“…It has been established that the strengths of Perplexity AI include the provision of precise sources and follow-up questions alongside query responses; effective handling of general knowledge, reasoning, and ev- idence-based content; reliable responses supported by relevant data; extensive search capabilities; a focus on clarity and efficiency of answers; the ability to sustain long-form conversations; and maintenance of con- text in extended interactions. …”
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Nivolumab plus cabozantinib in metastatic renal cell carcinoma: real-world evidence from the international ARON-1 study by Maria T. Bourlon, Maria T. Bourlon, Luca Galli, Enrique Grande, Se Hoon Park, Bohuslav Melichar, Timothy J. Schieber, Maria José Juan-Fita, Yüksel Ürün, Javier Molina-Cerrillo, Teresa Alonso-Gordoa, Ugo De Giorgi, Jakub Kucharz, Esther Pérez Calabuig, Vincenza Conteduca, Tarek Taha, Tarek Taha, Pasquale Rescigno, Hussam Abu-Sini, Gian Paolo Spinelli, Ray Manneh Kopp, Alessia Salfi, Dipen Bhuva, Paola Valdez-Sandoval, Sofia Mendez-Bribiesca, Ondrej Fiala, Ondrej Fiala, Sebastiano Buti, Sebastiano Buti, Fernando Sabino Marques Monteiro, Fernando Sabino Marques Monteiro, Aristotelis Bamias, Marwan Ghosn, Francesco Massari, Francesco Massari, Jawaher Ansari, Matteo Santoni

“…This sub-analysis is focused on the nivolumab plus cabozantinib effectiveness.MethodsWe conducted a retrospective study across 52 centers in 17 countries, including patients with metastatic renal carcinoma treated with first-line nivolumab plus cabozantinib, regardless of histologic characteristics, performance status, or risk by IMDC prognostic model. …”
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Treatment of unacceptable bleeding in long-term users of 52-mg levonorgestrel intrauterine device: a prospective observational studyAJOG Global Reports at a Glance by Patty A.H.H. van der Heijden, MD, Karlijn A. Röttgering, Tamara J. Oderkerk, MD, Jeanne P. Dieleman, Arianne C. Lim, PhD, Marlies Y. Bongers, PhD, Peggy M.A.J. Geomini, PhD

“…OBJECTIVE: This prospective observational study aimed to evaluate the effectiveness of estradiol in treating irregular bleeding in patients who have had a 52-mg levonorgestrel intrauterine device in place for at least 6 months. …”
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CXCR5 engineered human and murine Tregs for targeted suppression in secondary and tertiary lymphoid organs by Matteo Doglio, Jyoti Rana, Adriana Stucchi, Maite-Muñoz Melero, Alessia Ugolini, Tatiana Jofra, Cristiano Toma, Clara Bercher-Brayer, Pierluigi Carulli, Sandeep Kumar, Paolo Monti, Elisa Martini, Senthilkumar Thirumurugan, Moanaro Biswas, Chiara Bonini, Georgia Fousteri

“…Although antigen-specific regulatory T cells (Tregs), such as chimeric antigen receptor (CAR) Tregs, generally persist longer and localize to target tissues more effectively than polyclonal Tregs in animal models, their numbers still progressively decline over time. …”
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The Management and Prevention of Delirium in Elderly Patients Hospitalised in Intensive Care Units: A Systematic Review by Sarai Zaher-Sánchez, Pedro José Satústegui-Dordá, Enrique Ramón-Arbués, Jose Angel Santos-Sánchez, Juan José Aguilón-Leiva, Sofía Pérez-Calahorra, Raúl Juárez-Vela, Teresa Sufrate-Sorzano, Beatriz Angulo-Nalda, María Elena Garrote-Cámara, Iván Santolalla-Arnedo, Emmanuel Echániz-Serrano

“…Among the non-pharmacological and mixed therapies, bright light therapy was able to reduce the incidence of delirium, and the combination of epidural/general anaesthesia was effective in all subtypes of delirium. …”
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An explainable unsupervised learning approach for anomaly detection on corneal in vivo confocal microscopy images by Ningning Tang, Qi Chen, Yunyu Meng, Daizai Lei, Li Jiang, Yikun Qin, Xiaojia Huang, Fen Tang, Shanshan Huang, Qianqian Lan, Qi Chen, Lijie Huang, Rushi Lan, Xipeng Pan, Huadeng Wang, Fan Xu, Wenjing He

“…Furthermore, visualization results indicated that the detected anomalous regions corresponded to morphological deviations, highlighting potential imaging biomarkers for corneal diseases.ConclusionThis study presents an efficient and interpretable unsupervised anomaly detection model for IVCM images, effectively identifying corneal abnormalities without requiring labeled pathological samples. …”
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Intermittent hypoxia aggravates asthma inflammation via NLRP3/IL-1β-dependent pyroptosis mediated by HIF-1α signalling pathway by Ling Zhou, Huojun Zhang, Lu Liu, Fengqin Zhang, Lingling Wang, Pengdou Zheng, Zhenyu Mao, Xiaoyan Zhu, Guisha Zi, Lixiang Chen, Xiaojing Cai, Huiguo Liu, Wei Liu, Peifang Wei

“…An ovalbumin (OVA)-treated mouse model was also used to assess the effects of chronic intermittent hypoxia (CIH) on asthma. …”
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The use and impact of surveillance-based technology initiatives in inpatient and acute mental health settings: a systematic review by Jessica L. Griffiths, Katherine R. K. Saunders, Una Foye, Anna Greenburgh, Ciara Regan, Ruth E. Cooper, Rose Powell, Ellen Thomas, Geoff Brennan, Antonio Rojas-García, Brynmor Lloyd-Evans, Sonia Johnson, Alan Simpson

“…Abstract Background The use of surveillance technologies is becoming increasingly common in inpatient mental health settings, commonly justified as efforts to improve safety and cost-effectiveness. However, their use has been questioned in light of limited research conducted and the sensitivities, ethical concerns and potential harms of surveillance. …”
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