Using nonlinear model predictive control to find optimal therapeutic strategies to modulate inflammation by Judy Day, Jonathan Rubin, Gilles Clermont

“…In our simulations, NMPC successfully identifies patient-specific therapeutic strategies, based on simulated observations of clinically accessible inflammatory mediators, which outperform standardized therapies, even when the latter are derived using a general optimization routine. These results imply that a combination of computational modeling and NMPC may be of practical use in suggesting novel immuno-modulatory strategies for the treatment of intensive care patients.…”
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The National Program for Optimization of Provision with Vitamins and Minerals of Children in Russia. Summary Review of the Document by Vera M. Kodentsova, Leyla S. Namazova-Baranova, Svetlana G. Makarova

“…The first chapter of the document highlights  general issues including a definition of concepts, current  epidemiological data on provision, and methodological approaches.  …”
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Mathematical model of optimal placement of a hybrid power plant with a combined cycle by Ahmed Z. Abass, D. A. Pavlyuchenko, V. M. Less

“…This, in general, predetermines the highest final rating among all the provinces of Iraq as the optimal region for the location of a ISCC. …”
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Wavefront-optimized treatment for myopia using Allegretto Wave Eye-Q excimer laser by Celeste P. Guzman, MD, Jessica Marie R. Abaño, MD

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Optimization of time and temperature of dam construction for thermal analysis of roller compacted concrete dam by Ramtin Sobhkhiz Foumani, Alireza Mardookhpour, Forouzan Saberi

“…For the structure, hypothetical 50 cm layers are considered, each layer takes up 72 hours of analysis time. In general, the problem under analysis is analyzed 12 times. …”
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An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma by Michele Massimino, Elena Tirrò, Stefania Stella, Cristina Tomarchio, Sebastiano Di Bella, Silvia Rita Vitale, Chiara Conti, Marialuisa Puglisi, Rosa Maria Di Crescenzo, Silvia Varricchio, Francesco Merolla, Giuseppe Broggi, Federica Martorana, Alice Turdo, Miriam Gaggianesi, Livia Manzella, Andrea Russo, Giorgio Stassi, Rosario Caltabiano, Stefania Staibano, Paolo Vigneri

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Structural Optimization and Thermal Management with PCM-Honeycomb Combination for Photovoltaic-Battery Integrated System by Xinxi Li, Jiangyun Zhang, Dequan Zhou, Guoqing Zhang, Hongwei Wu, Rensheng Liu

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Improved Fuel Consumption Estimation for Sailing Speed Optimization: Eliminating Log Transformation Bias by Qi Hong, Xuecheng Tian, Yong Jin, Zhiyuan Liu, Shuaian Wang

“…By analyzing the characteristics of the objective function, we derive parameter constraints and integrate them into a discrete optimization framework, resulting in improved fitting accuracy. …”
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Waiting Experience: Optimization of Feedback Mechanism of Voice User Interfaces Based on Time Perception by Junfeng Wang, Yue Li, Shuyu Yang, Shiyu Dong, Jialin Li

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An optimal scheduling strategy for mountainous microgrids considering user-side shared energy storage by FU Linbei, WANG Haisheng, LI Zhongzhong, MA Lihong, ZHOU Hang, ZHANG Changjun, CUI Jianzhao

“…Simulations are performed using the ANTIGONE1.1 solver in the general algebraic modeling system （GAMS）. The results demonstrate that the proposed strategy outperforms traditional scheduling strategies by improving renewable energy utilization， reducing system CO₂ emissions， and lowering the total cost.…”
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A Study of the Optimal Logic Combinations of RO-Based PUFs on FPGAs to Maximize Identifiability by Raúl Aparicio-Téllez, Miguel Garcia-Bosque, Guillermo Díez-Señorans, Francisco Aznar, Santiago Celma

“…For this purpose, Generalized Galois Ring Oscillators (GenGAROs) are used. …”
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Predicting the geometry of stable alluvial channels: combination of data mining and meta-heuristic optimization by Fatemeh Lanjabi Sharahi, Seyed Morteza Seyedian, Mahmood Akbari, Ali Heshmatpour

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Optimization and Evaluation of Column Efficiency in RP-HPLC Method for Pharmaceutical and Forensic Drug Analysis by Khalid Sajjad Feras, Tahir Jamshaid, Majed Musalim Albluwi, Umair Ikram Dar, Abid Hussain

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The choice of the optimal braking force on the wheelset, taking into account the imper-fection of antiskid devices by I. A. Zharov, S. B. Kurtsev, A. A. Makas

“…In addition, exceeding the deceleration value of 2.5 m / s2 (coefficient of traction of the train above 0.25) can lead to disruption of the longitudinal stability of the track to shift.In general, the analysis of simulation results shows that the choice of the upper limit for the coefficient of adhesion = 0.3, laid down by the state standard for electric trains, is sufficiently substantiated. …”
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Compare of Transient Quality in Automatic Control Systems with Classic PID Algorithm and Optimal Regulator by G. T. Kulakov, K. I. Artsiomenka

“…This results in arising a problem of substantiation of the best structure and method of parametric optimization of classical PID regulators. …”
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Surface Defect Detection for Small Samples of Particleboard Based on Improved Proximal Policy Optimization by Haifei Xia, Haiyan Zhou, Mingao Zhang, Qingyi Zhang, Chenlong Fan, Yutu Yang, Shuang Xi, Ying Liu

“…On the particleboard defect dataset with limited images, PPOBoardNet achieves a mean average precision (mAP) of 79.0%, representing a 5.3% performance improvement over the YOLO series of optimal detection models. This result provides a novel technical approach to the challenge of defect detection with limited samples in the particleboard domain, with significant practical application value.…”
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Optimization, kinetics, physicochemical and ecotoxicity studies of Fenton oxidative remediation of hydrocarbons contaminated groundwater by W.O. Medjor, O.N. Namessan, Eunice Adebowale Medjor

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Exploring novel magnetic nanocomposite coagulants utilization for advanced drilling wastewater treatment and optimization by Behrad Shadan, Reza Gharibshahi, Arezou Jafari

“…The highest experimental values were 63.12% for TDS removal, 78.78% for TSS removal, and 10.61 NTU/min for TRR. Optimal results of 61.97% TDS removal, 79.00% TSS removal, and 5.03 NTU/min TRR were achieved using 0.50 g/L PAC, 0.40 g/L PAM, and 0.17 g/L MNP in the general optimization scenario without TRR boundary constraints.…”
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Metamodel-Based Optimization Method for Traffic Network Signal Design under Stochastic Demand by Wei Huang, Xuanyu Zhang, Haofan Cheng, Jiemin Xie

“…Numerical results show that the gradient-based metamodel method can effectively improve the computation efficiency while slightly reducing the solution optimality (with an increase of 0.09% in the expected total travel cost).…”
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Botox’s Place in the Complex Treatment of Oculomotor System Pathology (the Optimal “Portrait” of the Patient for the Chemodenervation) by I. L. Plisov, V. V. Cherhykh, V. V. Atamanov, N. G. Antsiferova, V. B. Pushchina, T. K. Istomina

“…Injection of Botox into the extraocular muscles in all cases was the primary method of treatment.Results. In general, the state of relative functional recovery was achieved in 71.81% of cases (in 270 patients). …”
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