Potassium channel clustering: mechanisms shaping axonal excitability by Gabriel Escobedo, Matthew N. Rasband

“…This review explores the diversity of potassium channels and the mechanisms responsible for their clustering at AIS and nodes of Ranvier. Understanding these processes will be essential for therapeutic strategies aimed at treating diseases characterized by abnormal potassium channel expression, clustering, and function in neurons.…”
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Collagen gene signature in the tumor microenvironment predicts survival and guides prognosis in bladder cancer by Yi Huang, Shuogui Fang, Weibin Xie, Yitong Zou, Hui Zhuo, Gang Shen, Hua Zhou, ChunPing Mao, Cong Lai, Jianqiu Kong, Xinxiang Fan

“…Abstract Background Collagen, within the tumor microenvironment (TME), assumes a crucial function in the development of cancer. However, the expression of collagen genes in bladder cancer (BCa) remains inadequately comprehended. …”
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MICROSURGICAL METHODS OF EX VIVO EXAMINATION OF THE LYMPHATIC SYSTEM IN BREAST CANCER PATIENTS by S. K. Gantsev, M. A. Tatunov, K. S. Gantsev, S. R. Kzyrgalin, R. S. Mukhamedyarov

“…Lymph nodes affected with metastatic breast cancer were examined. …”
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Habitat conditions of reef-forming corals directly affect the spatial distribution and stability in fish and macroinvertebrate communities: A case study of Mischief Reef by Peng Xu, Jianfeng Gan, Lintao Huang, Danping Xie, Feilong Li, Hui Huang

“…Nevertheless, the low functional redundancy of Lcrc indicates its relative vulnerability and poorer resistance to disturbances in the event of key functional organism loss. …”
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Algorithms of the Method of Statically Admissible Discontinuous Stress Fields (SADSF) – Part II: The Algorithms for Solving Limit Stress Fields Around Isolated Nodes of Stress Disc... by W. Bodaszewski

“…SUMMARY OF PART II: In the paper, the author introduces the sets of conditions that create the algorithms of the functions on which one defines the boundary problems met in the search for discontinuous limit fields existing around isolated nodes. …”
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Single‐cell RNA‐sequencing and spatial transcriptomic analysis reveal a distinct population of APOE− cells yielding pathological lymph node metastasis in papillary thyroid cancer... by Guohui Xiao, Rongli Xie, Jianhua Gu, Yishu Huang, Min Ding, Dongjie Shen, Jiqi Yan, Jianming Yuan, Qiong Yang, Wen He, Siyu Xiao, Haizhen Chen, Dan Xu, Jian Wu, Jian Fei

“…A machine‐learning bioinformatics model based on scRNA‐seq data of in‐situ thyroid cancer tissue was established to predict lymph node metastasis.…”
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CCR2 recruits monocytes to the lung, while CX3CR1 modulates positioning of CD11cpos cells in the lymph node during pulmonary tuberculosis by Alexander Mohapatra, Brian A. Norris, Zachary Howard, Joel D. Ernst

“…We used mice expressing knock-in/knockout reporter alleles of Ccr2 and Cx3cr1 to interrogate their expression and function in monocyte-derived populations of the lungs and draining mediastinal lymph nodes during Mtb infection. …”
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Identification and functional characterization of cardiac pacemaker cells in zebrafish. by Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, Jeroen Bakkers

“…In the mammalian heart a conduction system of nodes and conducting cells generates and transduces the electrical signals evoking myocardial contractions. …”
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Modelling of concepts "purpose", "goal", "task", and "function" in law by Vytautas Čyras

“…A goal is associated with a predicate, which characterises the goal. A node represents a state, in which the predicate is true. …”
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Distributed dynamic mapping scheme based on cost function by Guo-dong GE, Yun-fei GUO, Ju-long LAN, Cai-xia LIU

“…For supporting efficient host mobility and mapping identifiers onto locators,a distributed dynamic mobility mapping scheme based on cost function was proposed.In the scheme,depending on the mobility pattern and communication feature,the communication of mobile node is divided into three communication models,namely,moving update model,balanced transmission model and resolving query model.In order to minimize the total resolving cost,three mapping approach are proposed based on distributed multicast,consistent hash functions and proactive sharing respectively in the mobile domain.For each mapping approach,corresponding registration update,resolution query and packet delivery strategies are designed.Simulation results show that the scheme can achieve the minimum resolving cost,and can have low resolve latency and good adaptability for network topology dynamic changing.…”
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On the limits of the intervention on complex systems guided by functional networks by Massimiliano Zanin

“…We here test this assumption using a minimal model, simulating a propagation process in a physical network, and guiding interventions using node properties observed in the corresponding functional representation. …”
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Service function chain construct algorithm based on reliability by Julong LAN, Zijin JIN, Penghao SUN, Yiming JIANG, Yue WANG

“…With the continuous expansion of network size and content quantity,network operators often face the problem of data transmission interruption,thus how to improve the reliability of data transmission has become a research hotspot.Started with the huge advantages of NFV environment over traditional TCP/IP architecture based on the background that every network node has the capability of security service,a reliability algorithm for constructing functional service chains was proposed.First,the network topology was introduced and abstracted it into a digraph for a better analyzation.Then,several quantitative indices were used to define the upper and lower bounds of failure probability and resolved the model through a heuristic algorithm.The experimental results show that the proposed algorithm increases the reliability of service chain selection and spends less time.…”
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Effect of atmospheric particulate matter on the functional state of mitochondria by Elena V. Kondratyeva, Tatyana I. Vitkina

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Distributed dynamic mapping scheme based on cost function by Guo-dong GE, Yun-fei GUO, Ju-long LAN, Cai-xia LIU

“…For supporting efficient host mobility and mapping identifiers onto locators,a distributed dynamic mobility mapping scheme based on cost function was proposed.In the scheme,depending on the mobility pattern and communication feature,the communication of mobile node is divided into three communication models,namely,moving update model,balanced transmission model and resolving query model.In order to minimize the total resolving cost,three mapping approach are proposed based on distributed multicast,consistent hash functions and proactive sharing respectively in the mobile domain.For each mapping approach,corresponding registration update,resolution query and packet delivery strategies are designed.Simulation results show that the scheme can achieve the minimum resolving cost,and can have low resolve latency and good adaptability for network topology dynamic changing.…”
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Changes in gait biomechanics as functional symptom of chondromalacia patella by Aljona V. Altukhova, Sergey N. Kaurkin, Dmitry V. Skvortsov, Alexander A. Akhpashev, Nikolay V. Zagorodniy

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479 Effects of extracellular matrix on pacemaking cardiomyocyte function by Brian Howard, Regan Smithers, Kaitlin Van Brusselen, Hillary K.J. Kao, Deborah K. Lieu

“…Objectives/Goals: The extracellular matrix (ECM) of the sinoatrial node (SAN) is critical for maintaining automaticity in hiPSC-derived pacemaking cardiomyocytes (PCMs) under cyclic strain. …”
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GENERAL AND SPECIFIC STRUCTURAL CHANGES OF LYMPHOID ORGANS IN THE HIGH DOSE APPLICATION OF SODIUM SELENITE by I. Putalova, O. Zayko, A.Sindireva, O. Grinenko, I. Kosheleva

“…The morphometric research of the thymus, group lymphoid nodules, mesenteric lymph nodes, spleen, and laboratory investigation of blood were performed. …”
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CONCEPTION OF LEVEL OF SERVICE OF PUBLIC INTERMODAL TRANSPORT JUNCTIONS by T. A. Kopylova

“…Supposition was made by author about the main indicator of service level of intermodal nodes functional which is used to estimate the transport junction. …”
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Research on key "acupoint" mining technology for special information system by ZOU Zilong, WANG Junlin, AN Shujie, LYU Changyuan, YU Minggang, NIU Yanjie

“…Special information system is a complex information system with specific architecture, clear functional positioning, and diverse components and relationships among elements, and the key point refers to the node or component element that plays a key role in the system, and the damage of "acupuncture point" will have a huge impact on the function and utility of the whole system. …”
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Optimization of Filter Considering Harmonic Resonance in the Distribution Network by XIA Xiangyang, XU Linju, LUO Shiwu

“…In order to avoid the harm on the filter caused by the resonance between the passive part of the filter device and the grid, taking account of the harmonic resonance, resonance detection principle is adopted to optimize the configuration of the filter device. Through analysis of node admittance matrix feature values for the distribution network, the resonant position and resonant frequency are detected according to the impedance spectrum curves. …”
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