Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME) is different in children compared to in adults: a study of UK and Dutch clinical cohorts by Esther Crawley, Elise M van de Putte, Sanne L Nijhof, Simon M Collin, Roberto Nuevo

“…Adolescents were more likely to have headaches (81.1%, OR 1.56 (1.36% to 1.80%)) and less likely to have tender lymph nodes, palpitations, dizziness, general malaise and pain, compared to adults. …”
Get full text

A Hybrid Path Planning Algorithm for Orchard Robots Based on an Improved D* Lite Algorithm by Quanjie Jiang, Yue Shen, Hui Liu, Zohaib Khan, Hao Sun, Yuxuan Huang

“…Moreover, the number of hazardous nodes, defined as path points near obstacles, was reduced to five, marking decreases of 92.86% and 68.75%, respectively, and substantially enhancing navigation safety. …”
Get full text

Nuclear medicine in prostate cancer: A new era for radiotracers by Vincenzo Cuccurullo, Giuseppe Di Stasio, Luigi Mansi

“…In this scenario, remaining actual the clinical interest of bone scan (BS) in detecting skeletal metastases, an important role in diagnostic imaging may be also carried out by, positron emission tomography/computed tomography (PET/CT) and PET/magnetic resonance imaging (PET/MRI), which combine morphological information provided by CT and MRI with functional and metabolic data provided by PET acquisitions. …”
Get full text

Optical coherence tomography in preclinical diagnosis of optic nerve disk changes after chemotherapy in children with retinoblastoma by S. V. Saakyan, E. B. Myakoshina, V. G. Polyakov, T. L. Ushakova, D. M. Ismailova

“…Of these, 58 affected eyes before treatment belonged to groups А (3), В (16), С (33), D (3), and Е (3). All tumor nodes were located on the fundus outside the optic disk. …”
Get full text

Unlocking The Potential of Hybrid Models for Prognostic Biomarker Discovery in Oral Cancer Survival Analysis: A Retrospective Cohort Study by Leila Nezamabadi Farahani, Anoshirvan Kazemnejad, Mahlagha Afrasiabi, Leili Tapak

“…A protein-protein interaction (PPI) network was constructed, including 200 nodes and 120 edges. Eleven key genes with the highest degree, including RBM25, SMC3, PRPF40A, POLE, SRRT, BCLAF1, PDS5B, HNRNPR, JAK1, MED23, and SULT1A1 were identified as significant biomarkers associated with OC survival.Conclusion: The PSO-based hybrid model effectively improved SVR performance in survival prediction for OC patients and identified key prognostic biomarkers. …”
Get full text

Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease by Rukshan Ahamed Mohamed Rafeek, Natkunam Ketheesan, Michael F. Good, Manisha Pandey, Ailin Lepletier

“…In animals injected with rM5 and treated with LD-IL-2, no cardiac functional or histological changes was observed. LD-IL-2 therapy effectively reduced the production of cross-reactive antibodies raised against host proteins and significantly increased regulatory T cells in the mediastinal lymph nodes. …”
Get full text

Metastatic Adamantinoma of Fibula to the Lungs: A Rare Case Report by Knaj D, Ahmad G, Alshehabi Z, Ahmad IY

“…CT scan showed a 12× 13 cm mass in the left popliteal region extending to the knee margin. Enlarged lymph nodes were noted in the left groin. Multiple small metastases were observed in the lungs. …”
Get full text

Embryonal biliary rhabdomyosarcoma in a 4-year-old female: a case report by Abdullah Nofal, Somaya Al Kiswani, Zaid Sawaftah, Nader Sarhan, Ali Bani Odah, Humam Emad Rajha

“…Multiple enlarged lymph nodes were also observed. Porta hepatic core needle biopsy and histopathological analysis confirmed EBRMS, immunohistochemically positive for desmin and myogenin. …”
Get full text

Different Fish Farming Patterns in Paddy Fields Substantially Impact the Bacterial Community Composition, Stability, and Assembly Processes in Paddy Water by Yiran Hou, Rui Jia, Linjun Zhou, Liqiang Zhang, Bing Li, Jian Zhu

“…To evaluate the environmental impacts of partitioned rice–fish farming on the agricultural ecosystem, we investigated the impacts of partitioned rice–fish farming on the diversity, composition, functionality, co-occurrence networks, and assembly processes of bacterial communities within paddy water. …”
Get full text

ADAR1 Promotes Myogenic Proliferation and Differentiation of Goat Skeletal Muscle Satellite Cells by Zihao Zhao, Miao Xiao, Xiaoli Xu, Meijun Song, Dinghui Dai, Siyuan Zhan, Jiaxue Cao, Jiazhong Guo, Tao Zhong, Linjie Wang, Li Li, Hongping Zhang

“…Here, we explored the functions of ADAR1 in the myogenic process of goat skeletal muscle satellite cells (MuSCs). …”
Get full text

The transhiatal tunnel valvuloplasty technique following laparoscopic proximal gastrectomy: the single-center experience in a retrospective cohort by Chunguang Guo, Zefeng Li, Xin Guo, Yong Liu, Dong Qu, Zhaodong Xing, Hu Ren, Chongyuan Sun, He Fei, Xiaojie Zhang, Lei Ge, Yanwei Gao, Enjun Li, Chaodong Yin, Jing Zhang, Guiqi Wang, Dongbing Zhao

“…The further verification of the esophageal function is warranted.…”
Get full text

Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses by Cody J Warren, Arturo Barbachano-Guerrero, Vanessa L Bauer, Alex Stabell, Obaiah Dirasantha, Qing Yang, Sara L Sawyer

“…First, we reconstructed and tested ancient forms of CD4 at two important nodes in ape speciation, both prior to the infection of chimpanzees and gorillas with these viruses. …”
Get full text

Duodenal tuberculosis with gastric outlet obstruction: a case report of successful diagnosis and treatment, with review of literature by Nami Sato, Masayuki Shiobara, Kazuo Wakatsuki, Kosuke Suda, Kotaro Miyazawa, Toshiaki Aida, Yoshihiro Watanabe, Katsunobu Tawada, Yoshiki Matsubara, Yohei Hosokawa, Shigeru Yoshioka

“…Computed tomography (CT) showed the duodenal wall thickening, luminal narrowing, multiple enlarged abdominal lymph nodes, and portal vein stenosis. Conventional mucosal biopsy during endoscopy revealed ulcer scars. …”
Get full text

Metastasis of Squamous Cell Carcinoma of the Larynx to the Right Adrenal Gland—A Case Report by Eliza Działach, Michał Simlot, Karolina Osowiecka, Elżbieta Nowara, Jarosław Markowski, Mateusz Grajek

“…Squamous cell carcinoma (SCC) of the larynx is a prevalent head and neck cancer that typically spreads to the cervical lymph nodes, with distant metastases being rare. Among such metastases, adrenal gland involvement is particularly uncommon, presenting unique diagnostic and therapeutic challenges. …”
Get full text

The outcomes of salvage robotic radical prostatectomy following radiation versus focal therapy: Does the primary treatment modality matter? by Alireza Ghoreifi, Lorenzo Storino Ramacciotti, Masatomo Kaneko, Luis G. Medina, Giovanni E. Cacciamani, Shiran Konganige, Manju Aron, Sarmad Sadeghi, Hossein Jadvar, Hooman Djaladat, Rene Sotelo, Mihir M. Desai, Inderbir S. Gill, Monish Aron, Andre Luis Abreu

“…Perioperative findings and functional/oncologic outcomes were compared in RT versus FT groups. …”
Get full text

Utility of [18F]FDG PET/CT in sarcoidosis management: A retrospective case series by Mourad Zekri, Majdouline Bel Lakhdar, Dounia Alami, Soumia Kriouile, Leila Achachi, Abdellah Achir, Hicham Harmouche, Ayat Mouaden, Hasnae Guerrouj, Imad Ghfir

“…Additionally, 60% of patients displayed associated extrathoracic activity, mainly in peripheral lymph nodes, spleen, and bone. Cardiac activity was reported in two patients. [18F]FDG PET/CT prompted a diagnostic biopsy in 32% of patients. [18F]FDG PET/CT had an impact on therapeutic decision-making in 60% of patients. …”
Get full text

Multi-omics dissection of MAPK-driven senescence unveils therapeutic vulnerabilities in KIAA1549::BRAF-fusion pediatric low-grade glioma models by Romain Sigaud, Anja Stefanski, Florian Selt, Daniela Kocher, Diren Usta, Daniel Picard, Isabel Büdenbender, Marc Remke, Stefan M. Pfister, David T. W. Jones, Tilman Brummer, Olaf Witt, Till Milde

“…Trametinib treatment inhibited MAPK activity, OIS and SASP signatures across all omics levels, functionally underscored by reduced sensitivity towards senolytic drugs. …”
Get full text

Robust prediction of glioma prognosis by hypoxia-induced ferroptosis genes: VEGFA-XBP1 co-expression for salvage therapy by Zhou Liwei, Lu Hanwen, Zhao Wenpeng, Yu Weijie, Chen Sifang, Zhang Bingchang, Li Zhangyu, Gao Xin, Li Wenhua, Mao Jianyao, Xie Yuanyuan, Tan Guowei, Wang Zhanxiang

“…This study deciphers the functional role of hypoxia-induced ferroptosis in glioma prognosis. …”
Get full text

Diseño de un Software de Intermediación de Comunicación para Sistemas Distribuidos de Tiempo Real Críticos en Java by Daniel Tejera, Alejandro Alonso, Miguel A. de Miguel

“…The JRMP protocol was modified to include two phases, non-functional parameters, and message size optimizations. …”
Get full text

Lymphoproliferative disorders and renal dysfunction: a case of CLL-related AKI by Akhil Tomy, Aswathi Balakrishnan, Siva Shrikanth, Cristoss Gregory, Maria Elizabeth John, Tanushree Dewan

“…A blood film confirmed CLL, but there was no evidence of haemolysis. Renal function was significantly impaired, with creatinine of 296 µmol/L and an eGFR of 18 mL/min/1.73 m2. …”
Get full text