Glucose absorption in the duodenum is modulated by an estrogen receptor α-dependent regulation of glucose transporter functional expression by Xiaoxu Yang, Qian Du, Rui Xie, Jianhong Ding, Weixi Shan, Jingyu Xu, Changmei Chen, Qiushi Liao, Jun Lou, Zhe Jin, Mingkai Chen

“…In this study, we investigated the effects of estrogen on glucose absorption in humans, mice, and the human intestinal epithelium cell line SCBN.Research design and methods The ovariectomized (OVX) animal model was established. …”
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Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma by Jin-Xing Wang, Ling Zhang, Peng-Wei Zhang, Luo-Wei Yuan, Jian Jiang, Xiao-Hui Cheng, Wei Zhu, Yong Lei, Fa-Qing Tian

“…The viability of MM cell lines and patient bone marrow mononuclear cells (BMMCs) was measured via the CCK8 reagent. …”
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Lower extremity functional performance tests and their measurement properties in athletes: a systematic review and narrative synthesis by Alison Rushton, Nicola R Heneghan, Lee Herrington, James Martin, Rosalyn Cooke, Andy Soundy

“…Objective To identify functional performance tests (FPTs) with potential to identify athletes at risk of lower extremity injury (LEI) and assess their measurement properties.Design Systematic review conducted in line with Preferred Reporting Items for Systematic Reviews and Meta-Analyses and PRISMA in Exercise, Rehabilitation, Sports Medicine and Sports Science guidance.Data sources Two-stage systematic search of Medline, Embase, Cumulative Index to Nursing and Allied Health Literature and SPORTDiscus databases from inception to 24 November 2023, supplemented by hand searching of reference lists, key journals and grey literature.Eligibility criteria Search 1 identified FPT predicting LEI in athletes aged >16 years competing at elite, pre-elite or collegiate levels and feasible in the field. …”
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A dual-reporter LDLR system integrating fluorescence and luminescence for understanding LDLR regulation and facilitating drug discovery by Peng Jiao, Peng Jiao, Peng Jiao, Peng Jiao, Na Yang, Na Yang, Qianfeng Jia, Baozhen Fan, Ke Feng, Ke Feng, Jian Yu, Shengtian Zhao, Shengtian Zhao, Shengtian Zhao

“…The system was validated using western blotting, immunofluorescence, and functional assays, including DiI-LDL uptake and drug response analyses with statins and PCSK9 inhibitors.ResultsThe established LDLR-EGFP-Gluc knock-in cell line faithfully recapitulates endogenous LDLR expression and function. …”
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PD-1IR2 promotes tumor evasion via deregulating CD8+ T cell function by Xiaodong Wang, Shan Gao, Xiaofeng Zhu, Hongbo Hu, Fang Guo, Shuwen Cheng, Chang Huang, Haojing Zang, Tongfeng Liu, Liqiang Duan, Xujie Zhao, Xuetong Wang, Chang Zhang, Facai Yang, Yinmin Gu

“…PDCD1IR2 CKI mice which specifically conditional knock-in PDCD1IR2 in T cells and humanized peripheral blood mononuclear cells (PBMC)-NOG (NOD.Cg-PrkdcscidIL2rgtm1Sug/JicCrl) mice were utilized to further confirm the physiological function of PD-1IR2 in vivo.Results PD-1IR2 is expressed in a variety of human leukemia cell lines and tumor-infiltrating lymphocytes. …”
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Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population by Zhanyi Yang, Jiaai Xu, Xiaoyu Yang, Pengcheng Yi, Jian Ruan, Yingying Wu, Yushan Li, Geng Tian, Fuyi Xu, Jia Mi, He Li, Chunhua Yang

“…This research aims to elucidate the function of MORC4 in hepatic lipid metabolism, thereby improving the understanding of the molecular mechanisms underlying lipid metabolism disorders.MethodsData regarding circulating lipid traits and hepatic Morc4 expression in BXD mice were obtained from GeneNetwork. …”
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Software Design of Secondary Programmable and Debugging Development for Converter by 罗凌波, 戴计生, 尚敬

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Head Horn Enhances Hydrodynamic Perception in Eyeless Cavefish by Zhiqiang Ma, Zheng Gong, Yonggang Jiang, Peng Wu, Changxin You, Zihao Dong, Hongchao Cao, Zhen Yang, Yahui Zhao, Huawei Chen, Deyuan Zhang

“…Abstract Fish can use hydrodynamic stimuli, decoded by lateral line systems, to explore the surroundings. Eyeless species of the genus Sinocyclocheilus have evolved conspicuous horns on their heads, whereas the specific function of which is still unknown. …”
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Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…Here, we established a monoclonal cell line that consistently expresses Cas9 and can be used for screens to determine gene function or antiviral activity. …”
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Research on the Intelligent Bus Scheduling System Based on Genetic Algorithm by LIU Jiguo

“…Aiming at the problem of bus scheduling optimization, it analyzed the bus line model and the hierarchical characteristics of different levels of bus lines, proposed a bus scheduling model based on genetic algorithm and established the objective function and constraints. …”
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Understanding quality of life in Danish women with metastatic breast cancer undergoing multiple treatments by Helle Pappot, Annasofie Jørgensen, Anna Hincheli Bjørum, Christina Bøgh Jakobsen, Camilla Uhre Jørgensen, Beverley Lim Høeg, Pernille Bidstrup, Ann Knop, Line Bentsen

“…Interpretation: Women with mBC experience a substantial symptom burden and reduced functioning, and their QoL differs with successive lines of treatment. …”
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Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells by Nancy T Santiappillai, Yue Cao, Mariam F Hakeem-Sanni, Jean Yang, Lake-Ee Quek, Andrew J Hoy

“…Abstract Large-scale metabolomic analyses of pan-cancer cell line panels have provided significant insights into the relationships between metabolism and cancer cell biology. …”
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Stability Analysis of SEIAR Model with Age Structure Under Media Effect by Hongliang Gao, Fanli Zhang, Jiemei Li

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Antioxidant and Anticancer Activities of Silver Nanoparticles Synthesized Using Cinnamon Extracts by Khalidah Khalaf Jabbar, Mohamed Bouaziz

“…Additionally, the synthesized Ag NPs/cinnamon exhibited notable activity against the HepG-2 cell line. …”
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The Cosmic Evolution and Spatial Distribution of Multiphase Gas Associated with QSOs by Zeyu Chen, Enci Wang, Hu Zou, Haoran Yu, Zhicheng He, Huiyuan Wang, Yang Gao, Cheqiu Lyu, Cheng Jia, Chengyu Ma, Weiyu Ding, Runyu Zhu, Xu Kong

“…Additionally, the W of these absorption lines decreases with distance ( D ) from QSOs, which can be effectively characterized by a two-halo model. …”
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The efficacy and safety of immune combination therapy in patients with driver gene-negative non-small cell lung cancer with liver metastasis: a systematic review and network meta-a... by Weixing Zhao, Bo Li, Yujia Gu, Xiaoni Jin, Zirui Li, Wanjing Guo, Xinxin Lu, Jun Jiang

“…Enhanced monitoring of liver function is recommended because of the risk of hepatotoxicity. …”
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Digital Platform: a New Business Model in the Russian Economy by A. I. Gretchenko, I. V. Gorokhova

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POWER CONTROL OF PSEUDOLITES WHILE LANDING AN AIRCRAFT by V. V. Erokhin

“…The effect of a pseudolite (PL) signal on quality of functioning of the GLONASS/GPS receivers of satellite navigation has been researched and experimental confirmation of near-far effect developing with the help of NI GPS Simulation Toolkit hardware and software has been obtained. …”
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Competitiveness of Business Projects in Service Sector by E. G. Neofitu

“…The author researches their impact on services rendered in digital and off-line format. The model put forward in the article can be used by entrepreneurs to develop steps aimed at raising competitiveness of business.…”
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Stability Optimization of Explicit Runge–Kutta Methods with Higher-Order Derivatives by Gerasim V. Krivovichev

“…Thus, the integral characteristics of stability domains can be considered as functions of free parameters. The optimization is based on the numerical maximization of the area of the stability domain and the length of the stability interval. …”
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