Tumor suppressing function of SLC16A7 in bladder cancer and its pan-cancer analysis by Mingjie Xu, Jiatong Zhou, Jiancheng Lv, Yu Zhang

“…Functional studies included proliferation assays to investigate the effect of SLC16A7. …”
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Characterization and function of the first antibiotic isolated from a vent organism: the extremophile metazoan Alvinella pompejana. by Aurélie Tasiemski, Sascha Jung, Céline Boidin-Wichlacz, Didier Jollivet, Virginie Cuvillier-Hot, Florence Pradillon, Costantino Vetriani, Oliver Hecht, Frank D Sönnichsen, Christoph Gelhaus, Chien-Wen Hung, Andreas Tholey, Matthias Leippe, Joachim Grötzinger, Françoise Gaill

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FORMALIZATION OF THE STAGE OF SEARCHING FOR MODULATED SIDE ELECTROMAGNETIC RADIATIONS AND INTERFERENCES IN THE PROCESS OF MODELING THE FUNCTION OF INTERCEPTING THESE SIGNALS by Aleksey A. Petlevanny, Tatyana V. Meshcheryakova, Aleksandr I. Boronenkov, Vadim I. Spivak, Varvara A. Vladychenskaia

“…The procedure for performing these procedures is described in terms of functional diagrams. The transition from the representation of the studied processes in the form of functional diagrams to the representation in the form of Markov processes is illustrated. …”
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Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function. by Laura M Timmerman, J Fréderique de Graaf, Nikolaos Satravelas, Çan Kesmir, Linde Meyaard, Michiel van der Vlist

“…Therefore, we investigated whether additional motifs specify the inhibitory function of CD200R. We performed phylogenetic analysis of the intracellular domain of CD200R in mammals, birds, bony fish, amphibians and reptiles. …”
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Deep functional measurements of Fragile X syndrome human neurons reveal multiparametric electrophysiological disease phenotype by James J. Fink, Nathaniel Delaney-Busch, Ryan Dawes, Evanthia Nanou, Christopher Folts, Karthiayani Harikrishnan, Chris Hempel, Hansini Upadhyay, Trinh Nguyen, Himali Shroff, David Stoppel, Steven J. Ryan, Jane Jacques, Jennifer Grooms, Elizabeth Berry-Kravis, Mark F. Bear, Luis A. Williams, David Gerber, Mark Bunnage, Brinley Furey, Graham T. Dempsey

“…FMRP plays important roles in neuronal function, and loss of FMRP in mouse and human FXS cell models leads to aberrant synaptic signaling and hyperexcitability. …”
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Bavachin enhances paclitaxel sensitivity in ovarian cancer cells through modulation of mitochondrial function and ER stress by Sang-Jin Lee, Kee K. Kim, Jin-Young Lee

“…Mechanistically, bavachin disrupted mitochondrial function by inducing membrane depolarization and calcium dysregulation, leading to comprehensive impairment of cellular bioenergetics including both oxidative phosphorylation and glycolysis. …”
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Anatomy and transcriptomics of the common jingle shell (Bivalvia, Anomiidae) support a sensory function for bivalve tentacles by Jorge A. Audino, Kyle E. McElroy, Jeanne M. Serb, José E. A. R. Marian

“…Here, we gather multiple lines of evidence to explore the specialized sensory function of bivalve tentacles in the common jingle shell, Anomia simplex. …”
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Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse. by Tia DiTommaso, Lynelle K Jones, Denny L Cottle, WTSI Mouse Genetics Program, Anna-Karin Gerdin, Valerie E Vancollie, Fiona M Watt, Ramiro Ramirez-Solis, Allan Bradley, Karen P Steel, John P Sundberg, Jacqueline K White, Ian M Smyth

“…Many of these were not previously associated with skin disease in the organ (Mysm1, Vangl1, Trpc4ap, Nom1, Sparc, Farp2, and Prkab1), while others were ascribed new cutaneous functions on the basis of the screening approach (Krt76, Lrig1, Myo5a, Nsun2, and Nf1). …”
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Anapc5 and Anapc7 as genetic modifiers of KIF18A function in fertility and mitotic progression by Carleigh Nesbit, Whitney Martin, Anne Czechanski, Candice Byers, Narayanan Raghupathy, Ardian Ferraj, Jason Stumpff, Laura Reinholdt

“…Abstract The kinesin family member 18 A (KIF18A) is an essential regulator of microtubule dynamics and chromosome alignment during mitosis. Functional dependency on KIF18A varies by cell type and genetic context but the heritable factors that influence this dependency remain unknown. …”
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Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1. by Pablo J Fernandez-Marcos, Cristina Pantoja, Agueda Gonzalez-Rodriguez, Agueda Gonzalez-Rodriguez, Nicholas Martin, Juana M Flores, Angela M Valverde, Eiji Hara, Manuel Serrano

“…We conclude that Sei1 plays an important role in pancreatic beta-cells, which supports a functional link between Sei1 and the core cell cycle regulators specifically in the context of the pancreas.…”
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P42 | PANCREATIC CANCER STEM CELLS AND FUNCTIONAL CHARACTERIZATION OF MIR-216A-5P

“…Moreover, they corroborate our previous findings about miR-216a-5p’s potential dual role and miR-125a-5p’s promotive function in PDAC. …”
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A cross-entropy corrected hybrid multiconfiguration pair-density functional theory for complex molecular systems by Rulin Feng, Igor Ying Zhang, Xin Xu

“…The B3LYP-like translated on-top functional (tB4LYP) developed along this line not only surpasses the accuracy of its parent methods, the complete active space self-consistent field (CASSCF) and the original MC-PDFT functionals (tBLYP and tB3LYP), but also outperforms the widely used complete active space second-order perturbation theory (CASPT2). …”
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Human Adipose Derived Cells in Two- and Three-Dimensional Cultures: Functional Validation of an In Vitro Fat Construct by Robert Bender, Michelle McCarthy, Theodore Brown, Joanna Bukowska, Stanley Smith, Rosalyn D. Abbott, David L. Kaplan, Christopher Williams, James W. Wade, Andrea Alarcon, Xiying Wu, Frank Lau, Jeffrey M. Gimble, Trivia Frazier

“…The “fat-on-chip” 3D cultures have been validated relative to 2D cultures based on proliferation, flow cytometry, adipogenic differentiation, confocal microscopy/immunofluorescence, and functional assays (adipokine secretion, glucose uptake, and lipolysis). …”
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Physicochemical and functional properties of rainbow trout (Oncorhynchus mykiss) skin gelatin in comparison to commercial bovine gelatin by Muhammad Usman, Joe Mac Regenstein, Hafiz Ubaid Ur Rahman, Amna Sahar, Rana Muhammad Aadil, Amna Tariq, Ieaman Fatima, Ahmad Bilal, Lili He

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Loss of Pleiotropic Regulatory Functions in Tannin1, the Sorghum Ortholog of Arabidopsis Master Regulator TTG1 by Anthony Schuh, Geoffrey P. Morris

“…We characterized genome‐wide differential expression of leaf tissue using RNA sequencing in near‐isogenic lines (NILs) that contrasted wildtype Tan1 and loss‐of‐function tan1‐b alleles, under optimal temperature and chilling stress. …”
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Administrative and Legal Principles of Prosecutor’s Office Interaction with Public Administration Entities on the Issues of Performing Assigned Functions by A. Yu. Prokopenko, V. I. Kravtsov

“…The problem of legal regulation of interaction between the prosecutor’s office and public administration entities on the issues of performing the assigned functions has been studied. The research is based on studying such legislative acts as the Constitution of Ukraine, Laws of Ukraine “On Central Executive Agencies”, “On the Prosecutor’s Office”, “On the Status of MPs of Ukraine”, “On Temporary Investigative and Special Commissions of the Verkhovna Rada of Ukraine” and other legislative acts and bylaws regulating the interaction of the prosecutor’s office with state authorities. …”
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Loss of function of MusaPUB genes in banana can provide enhanced resistance to bacterial wilt disease by Leena Tripathi, Valentine Otang Ntui, Samwel Muiruri, Trushar Shah, Jaindra Nath Tripathi

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Efficacy of acupuncture on cognitive function in poststroke depression: study protocol for a randomized, placebo-controlled trial by Ling Chen, Yi Chen, Lihua Wu, Wen Fu, Luanmian Wu, Wenbin Fu

“…Abstract Introduction Poststroke depression (PSD) is the most common mental complication after stroke and has a serious impact on functional outcomes and quality of life. Antidepressants are the first-line treatment for PSD, but many reported side effects remain. …”
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Prospects for increasing the functionality of milk-containing products through the use of non-traditional plant raw materials by E. A. Moliboga, L. M. Zavgorodnyaya

“…The main objective of the research is to develop a technology for a milk-containing product (drinking yoghurt) that includes several functions important for humans, namely, functional, diabetic, probiotic ones. …”
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A temporally restricted function of the dopamine receptor Dop1R2 during memory formation by Jenifer C Kaldun, Emanuele Calia, Ganesh Chinmai Bangalore Mukunda, Cornelia Fritsch, Nikita Komarov, Simon G Sprecher

“…To study the function of Dop1R2, we knocked it out conditionally in the mushroom body of Drosophila melanogaster, a well-studied brain region for memory formation. …”
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