Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling in the ES-2 Ovarian Carcinoma Cell Line, Influencing Cell Proliferation, Quiescence, and Chemoresistance in a Cell-of-Origin-Sp... by Isabel Lemos, Catarina Freitas-Dias, Ana Hipólito, José Ramalho, Fabrizio Carteni, Luís G. Gonçalves, Stefano Mazzoleni, Jacinta Serpa

“…<b>Results:</b> This study demonstrated that despite inducing similar effects, different variants of cfDNA promote different effects on cells derived from the ES-2 cell line. We observed instant reactions of adopting the metabolic profile that brings back the cell functioning of more favorable culture conditions supporting proliferation and resembling the cell of origin of the cfDNA variant, as observed in unselected ES-2 cells. …”
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Design and Construction of a Web-Based Fixed Asset Management System with a Combination of Straight Line Method, MAUT, and Telegram Bot Integration: Case Study of North Lombok Dist... by I Made Teguh Arthana, Ni Kadek Ayu Wirdiani, Desy Purnami Singgih Putri

“…This study uses the Straight Line Method to calculate asset depreciation, the MAUT Method to assist in decision-making for the elimination of damaged assets, and the Telegram Bot to send notifications from the website to each unit group in the hospital. …”
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Unraveling the in vitro antioxidant and neuroprotective potential of green amalgamated gold nanoparticles from Chang shuo huang ma (Corchorus olitorius (L)): Insights on SK-N-SH ne... by Basheerahmed Abdulaziz Mannasaheb, Ibrahim Ahmed Shaikh, Gurmeet Kaur Surindar Singh, Noordin Othman, Mohammed M. Ghoneim, Hanish Singh Jayasingh Chellammal

“…A dose-dependent cytotoxic effect was observed in normal L929 cell lines, with an IC50 value of 204.11 µg/mL. Potential neuroprotective effects were observed in SK-N-SH neuroblastoma cell lines against trimethyltin chloride (TMT) induced neurotoxicity. …”
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Estimation of System-Level Reliability Functions for the Power Grid Using Probabilistic Modeling and Monte Carlo Simulation by Ayman Faza

“…In this paper, we develop a simple probabilistic method for modeling power system reliability based on the knowledge of the system size, transmission line capacities, and the failure rate type of the transmission lines in the system. …”
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Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells. by Zhijuan Chen, Lingbao Ai, Mam Y Mboge, Chingkuang Tu, Robert McKenna, Kevin D Brown, Coy D Heldermon, Susan C Frost

“…We find the same pattern across a panel of TNBC and luminal breast cancer cell lines. This affords an opportunity to compare directly CAIX and CAXII function. …”
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CRISPR mutant rapid identification in B. napus: RNA-Seq functional profiling and breeding technology application by Rui Geng, Rui Geng, Xiang Fan, Rehman Sarwar, Rehman Sarwar, Yong Wang, Ke Dong, Xiao-Li Tan

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Exploring the role of methylation-driven gene IFFO1 in pancreatic adenocarcinoma diagnosis, prognosis and cellular functions by XU Ziqi, HU Ruizhi, LI Junjian, WANG Hongxia, SANG Youzhou

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Revised Control Barrier Function with Sensing of Threats from Relative Velocity Between Humans and Mobile Robots by Zihan Zeng, Silu Chen, Xiangjie Kong, Xiaojuan Li, Chi Zhang, Guilin Yang

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MiR-1202 functions as a tumor suppressor in glioma cells by targeting Rab1A by Yu Quan, Qian Song, Jvbo Wang, Lingyu Zhao, Jian Lv, Shouping Gong

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CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro by Beatriz Larraz-Prieto, Louise Hjorth Lind, Jacob Bastholm Olesen, Asim Azfer, Morten Svarer Hansen, Morten Frost, Abbas Jafari, Stuart H. Ralston, Kent Søe, Nerea Alonso

“…Methods: Primary murine and human osteoblasts and osteoclasts, MC3T3 cell lines, and hMSC-TERT4 cell lines were treated with TPTD and/or AMD3100, a pharmacological inhibitor of CXCR4. …”
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Identification of novel functional compounds from forest onion and its biological activities against breast cancer by Fahrul Nurkolis, Isma Kurniatanty, Elvan Wiyarta, Happy Kurnia Permatasari, Nelly Mayulu, Nurpudji Astuti Taslim, Raymond Rubianto Tjandrawinata, Hardinsyah Hardinsyah, Trina Ekawati Tallei, Apollinaire Tsopmo, Son Radu, Edwin Hadinata, Bonglee Kim, Rosy Iara Maciel Azambuja Ribeiro, Rony Abdi Syahputra

“…The discovery of new molecules from natural sources for the treatment of tumors such as breast cancers is of importance for the development of functional foods and to the pharmaceutical industry. …”
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A hybrid machine learning framework for functional annotation of mitochondrial glutathione transport and metabolism proteins in cancers by Luke Kennedy, Jagdeep K. Sandhu, Mary-Ellen Harper, Miroslava Cuperlovic-Culf

“…This framework achieves strong performance across functional annotation tasks and several cell line and primary tumor cancer samples. …”
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Functional circuits of LYL1 controlled by supraphysiological androgen in prostate cancer cells to regulate cell senescence by Mehdi Heidari Horestani, Katrin Schindler, Aria Baniahmad

“…The androgen receptor (AR) regulates the development and physiological function of normal prostate as well as the proliferation of cancerous prostate tissue. …”
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Magnetic iron-based nanoparticles encapsulated in graphene/reduced graphene oxide: Synthesis, functionalization and cytotoxicity tests by Aysa Azmoudeh, Sencer Moral, Seyma Sari, Miray Türk, Muhammet U. Kahveci, Gizem Dinler Doganay, Duygu Ağaoğulları

“…Subsequently, their surface modification was conducted with pyrene end-functional POEGMA obtained by atom transfer radical polymerization (ATRP). …”
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GEOECOLOGICAL ASPECTS OF THE CREATION AND FUNCTIONING OF THE NATURAL-TECHNIC SYSTEMS UNDER THE CONDITIONS OF THE WESTERN SIBERIA CRYOLITHIC ZONE by S. D. Ganova

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Predictive Factors for Morphological and Functional Improvements in Long-Lasting Central Serous Chorioretinopathy Treated with Photodynamic Therapy by Maciej Gawęcki, Krzysztof Kiciński, Jan Kucharczuk, Monika Gołębiowska-Bogaj, Andrzej Grzybowski

“…The goal of our study was to evaluate the morphological and functional effects of PDT in patients with long-lasting CSCR and determine the related predictive factors for improvement. …”
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Functional analysis of StWRKY75 gene in response to heat stress in potato (Solanum tuberosum L.) by Xi Zhu, Xi Zhu, Xi Zhu, Xiaoqin Duan, Xiaoqin Duan, Yasir Majeed, Yasir Majeed, Junfu Luo, Junfu Luo, Junfu Luo, Nengkang Guan, Nengkang Guan, Nengkang Guan, Haifei Zheng, Haifei Zheng, Haifei Zheng, Huafen Zou, Huafen Zou, Hui Jin, Hui Jin, Zhuo Chen, Zhuo Chen, Yu Zhang, Yu Zhang, Yu Zhang

“…To characterize its function, we generated transgenic lines overexpressing StWRKY75 (OE) or knockdown by RNA interference (RNAi). …”
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A general strategy to achieve see-through devices through the micro-structuring of colored functional materials by Zishou Hu, Xueqing Tang, Yuan-Qiu-Qiang Yi, Shuhong Nie, Xiaolian Chen, Wenya Xu, Chenchao Huang, Xinju Mu, Zhongsheng Ma, Pengyu Tang, Xinzhou Wu, Wenming Su, Christine K. Luscombe

“…We achieve this by structuring the colored functional materials into imperceptible three-dimensional mesh lines, addressing a common challenge in multi-layer structures where each layer causes a reduction in transparency due to their color or opacity. …”
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Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders by Ziqin Yang, Ziqin Yang, Nicole A. Teaney, Nicole A. Teaney, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Elizabeth D. Buttermore, Mustafa Sahin, Mustafa Sahin, Mustafa Sahin, Wardiya Afshar-Saber, Wardiya Afshar-Saber

“…Functional assays, including patch clamping, multielectrode array, and imaging-based assays, are popular tools employed with hiPSC disease models for disease investigation. …”
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Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. by Barbara Mair, Tomasz Konopka, Claudia Kerzendorfer, Katia Sleiman, Sejla Salic, Violeta Serra, Markus K Muellner, Vasiliki Theodorou, Sebastian M B Nijman

“…Here, we uncover a similar phenomenon for GATA3, a frequently mutated, yet poorly understood, breast cancer gene. We identify two functional classes of frameshift mutations that are associated with distinct expression profiles in tumours, differential disease-free patient survival and gain- and loss-of-function activities in a cell line model. …”
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