Biochemical and functional properties of vesicles from planktonic and biofilm phenotypes of Limosilactobacillus reuteri DSM 17938 by Beatrice Marinacci, Chiara D’Ambrosio, Irene Vitale, Antonella Di Sotto, Francesco Cairone, Mattia Spano, Simone Carradori, Andrea Scaloni, Marco Gullì, Valentina Puca, Santolo Francati, Monica Matuozzo, Ludwig Ermann Lundberg, Gianfranco Grompone, Stefan Roos, Rossella Grande

“…In this study, membrane vesicles isolated from planktonic (pMVs) and biofilm (bMVs) phenotypes were comparatively investigated for their toxicity, ability to kill cancer as well as non-cancer cell lines and modulate phagocytosis in murine macrophages. …”
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Point-of-Care Ultrasonography and Worsening of Renal Function in Acute Heart Failure: A Cohort Study by Guillaume Soret, Antonio Leidi, Alexandre Leszek, Christophe Marti, Sebastian Carballo, Jérôme Stirnemann, Olivier Grosgurin, Jean-Luc Reny, Thomas A. Mavrakanas

“…Introduction: The goal of this study was to investigate the association between worsening renal function (WRF) and central venous pressure, right ventricular function, and lung fluid overload assessed by point-of-care ultrasound (POCUS) in hospitalized patients with acute heart failure (AHF). …”
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Anti-Slip Control System with Self-Oscillation Suppression Function for the Electromechanical Drive of Wheeled Vehicles by Aleksandr V. Klimov, Akop V. Antonyan, Andrey V. Keller, Sergey S. Shadrin, Daria A. Makarova, Yury M. Furletov

“…This paper reviews the methods of designing an anti-slip control system for wheels with an oscillation damping function and studies the applicability and efficiency of the suggested method using mathematical simulation of the virtual vehicle operation in the Matlab Simulink software package. …”
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Enhanced porcine gut barrier functioning and reduced inflammation from a combination of seaweed  bioactives by Meike A. Bouwhuis, Irene H. G. Nooijen, Evita van de Steeg, Shane O’Connell

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Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G. by Robert A Eagle, Gillian Flack, Anthony Warford, Jesús Martínez-Borra, Insiya Jafferji, James A Traherne, Maki Ohashi, Louise H Boyle, Alexander D Barrow, Sophie Caillat-Zucman, Neil T Young, John Trowsdale

“…<h4>Methodology/principal findings</h4>We pursue a number of approaches to characterise the expression, trafficking, and function of the two isoforms of ULBP5/RAET1G. We show that both transcripts are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers. …”
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Functional evaluation of novel compound heterozygous variants in SLC12A3 of Gitelman syndrome by Na Wang, Yuanxing Yang, Xiong Tian, Hongjun Fu, Shuaishuai Chen, Juping Du, Mengyi Xu, Haixia He, Bo Shen, Jiaqin Xu

“…Conclusion Our study presents the genetic and functional evidence for the novel compound heterozygous loss-of-function variants in SLC12A3 that may synergistically cuase GS, and expands the mutation spectrum of SLC12A3 variants in patients with GS.…”
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Neural markers of methylphenidate response in children with attention deficit hyperactivity disorder and the impact on executive function by Anqi Wang, Anqi Wang, Hua Yang, Hua Yang, Yue Yang, Yue Yang, Jie Yang, Jie Yang, Xiaowen Yang, Xiaowen Yang, Qianhui Wen, Qianhui Wen, Qian Wang, Qian Wang, Hao Liu, Hao Liu, Rong Luo, Rong Luo

“…A core cognitive deficit in ADHD is executive function (EF) impairment, which significantly impacts daily life. …”
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Dosing of Antimycotic Treatment in Sepsis–Induced Liver Dysfunction by Functional Liver Testing with LiMAx® by Carmen Kirchner, Jasmin Sibai, Elke Schwier, Dietrich Henzler, Claas Eickmeyer, Günther Winde, Thomas Köhler

“…Although azoles are considered first-line treatment in these cases we chose the echinocandin caspofungin for its presumed lower impact on liver function compared to azoles like voriconazole or Amphothericin B. …”
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Features of the functioning of the hypothalamic-pituitary-thyroid axis in mice with Lewis carcinoma on the background of induced hyperthyroidism by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, I. V. Neskubina, E. I. Surikova, A. I. Shikhlyarova, L. K. Trepitaki, M. A. Gusareva, I. A. Udalenkova, E. O. Vasilieva, N. D. Cheryarina, V. V. Pozdnyakova

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Impact of functional re-education and environmental adaptation in cancer patients with respiratory pathology: Study protocol. by Eduardo Jose Fernandez-Rodriguez, Maria Isabel Rihuete-Galve, Alberto Garcia-Martin, Celia Sanchez-Gomez, Fausto Jose Barbero-Iglesias, Roberto Mendez-Sanchez, Ana Silvia Puente-Gonzalez, Susana Saez-Gutierrez, Emilio Fonseca-Sanchez, Juan Jesus Cruz-Hernandez

“…As the number of treatment lines has grown, so too have the side effects, which can severely impact patients' functionality and quality of life. …”
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eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants. by Alexis M Thornton, Lishan Fang, April Lo, Maria McSharry, David Haan, Casey O'Brien, Alice H Berger, Marios Giannakis, Angela N Brooks

“…The eVIP method uses a decision tree-based algorithm to predict the functional impact of somatic variants by comparing gene expression signatures induced by introduction of wild-type (WT) versus mutant cDNAs in cell lines. …”
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Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis by Shubin Wang, Xiangjie Yang, Xiangjun Liu, Qin Wen, Lu Xu, Mei Feng, Mei Feng, Jinyi Lang, Dengqun Liu, Dengqun Liu

“…The influence of iron on the barrier integrity and stem cell function was further determined by histology, IEC-6 cell, and enteroid culture. …”
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Development and mechanism study of functional fermentation media for reducing alkaloid content in cigar tobacco leaves by Wanrong Hu, Li Liu, Jiabao Zhang, Quanwei Zhou, Zhongrong Jiang, Yun Jia, Qianying Zhang, Dongliang Li

“…It also facilitated the proliferation of functional microorganisms such as Acinetobacter, Enterobacter, Pseudomonas, Wickerhamomyces, and Wallemia. …”
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Chemical-functional characterization of Ascophyllum nodosum and Phymatolithon calcareum and dietary supplementation in post-weaning pigs by Sara Frazzini, Serena Reggi, Matteo Dell’Anno, Anna Paola Fifi, Elena Scaglia, Elena Scaglia, Irene Ferri, Luciana Rossi

“…IntroductionAs the livestock industry grapples with the need for sustainable land, maintaining production systems, and reducing antimicrobial resistance, the application of functional nutrition emerges as a potential solution.AimIn line with the One Health principles, this study aims to evaluate functional properties of Ascophyllum nodosum and Phymatolithon calcareum, and assess the effects of their dietary supplementation on piglets’ health.Materials and methodsA chemical-functional characterization was conducted before and after in vitro digestion. …”
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Novel Trimethoprim-Based Metal Complexes and Nanoparticle Functionalization: Synthesis, Structural Analysis, and Anticancer Properties by Abbas M. Abbas, Hossam H. Nasrallah, A. Aboelmagd, W. Christopher Boyd, Haitham Kalil, Adel S. Orabi

“…Notably, all derivatives exhibited higher activity against the HepG-2 cancer cell line than TMP, except for HD, which showed similar effectiveness to TMP. …”
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Culioli, Adamczewski et la linguistique anglaise by Ariel Laurencio Tacoronte

“…This integrated model, built along Culiolian formalization parameters, allows us not only to analyze and better understand the enunciative functioning of the structure, or its equivalents in other languages, such as in French être en train de, but also to sketch, still within the enunciative framework, a new hypothesis on the possible metaphorical motivation of the latter.…”
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Protocol for the MERINO study: A randomized placebo-controlled trial assessing the efficacy, safety, and cost-effectiveness of methotrexate in people with erosive hand osteoarthrit... by Alexander Mathiessen, Line Gaundal, Joseph Sexton, Dag Sjølie, Pernille Steen Pettersen, Barbara Slatkowsky-Christensen, Ida Kristin Haugen

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Preliminary Test of Source Parameters of M_wp6 Italian Earthquakes: Revisiting Kinematic Function Method by Paolo Harabaglia, Massimiliano Iurcev, Denis Sandron, Teresa Tufaro, Marco Vona, Franco Pettenati

“…We present the inversion of macroseismic data as a first validation of an improved version of the kinematic function, KF. Following the previous results of some earthquakes on Italian territory and several validations by Californian events provided with instrumental solutions, we have now simplified the KF by reducing some degrees of freedom of the parameters and rearranging the code for parallel calculation. …”
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Potential Flow of Unburned Mixture and Combustion Products After Ignition in a Two-Dimensional Approximation by Sergey Golovastov

“…The method of conformal mapping was used. Simple analytical functions were used that allowed equipotential lines and streamlines to be transformed. …”
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Design and Application of Online Monitoring System for Catenary Compensation Device by Guangdong LIU, Mingli WU, Min WEI, Zhijie JIAO

“…In order to make up for the lack of detection methods for catenary in China, a set of on-line monitoring system for catenary compensation devices was designed, realizing the functions of collecting, transmitting, storing, displaying and analyzing the <italic>b</italic>-value of the catenary compensation device. …”
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