Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel by Haizhang Chen, Andrea Maul‐Pavicic, Martin Holzer, Magdalena Huber, Ulrich Salzer, Nina Chevalier, Reinhard E Voll, Hartmut Hengel, Philipp Kolb

Get full text

Transfer of preclinical study data on the influence of cimicifuga racemosaon functional changes in the hippocampus during menopause by Petra Stute, Hans-Heinrich Henneicke-von Zepelin, Petra Nicken

“…Focus was laid on changes in the hippocampal function, that is disturbed by hormonal fluctuations, but can also be brought back into balance by iCR.…”
Get full text

New ideas about the structure and functions of national ecological network in the context of modern postnonclassical concepts by Tetiana Kazakova

“…Thus the best “contact” between a man and nature should promote exactly informative and ideological functions performed by technogenesis objects. Such theoretical approach provides a new tool for the formalization of relations between nature and society in the organization of the environmental work including formation of the ecological network. …”
Get full text

The effect of functional movement screen and lower extremity training on hamstring/quadriceps ratio in football players by Akan Bayrakdar, Boz Hilal Kılınç

“…The aim of this study is to determine the effect of functional movement screen and lower extremity training on hamstring/quadriceps (H/Q) ratio in football players. …”
Get full text

Targeted delivery of doxorubicin to B-cell lymphoma using monoclonal antibody-functionalized Chaetoceros biosilica by Ghazal Salari, Ahmad Shadi, Amirhossein Ahmadi, Javid Esfandyari, Hossein Nikmanesh

“…This study investigates the effectiveness of porous biosilica derived from the diatom Chaetoceros sp., functionalized with hydrophilic GPTMS, labeled with CD-19 antibody, and loaded with doxorubicin in targeting Raji cells, a B lymphoid cell line. …”
Get full text

RETRACTED: Palmitic Acid Impedes Extravillous Trophoblast Activity by Increasing MRP1 Expression and Function by Yunali Ashar, Qiuxu Teng, John N. D. Wurpel, Zhe-Sheng Chen, Sandra E. Reznik

“…Palmitic acid increased <i>ABCC1</i> gene expression and MRP1 protein expression in both cell lines. The rate of folate efflux from the cells into the media increased with a decrease in migration and invasion functions in the cultured cells. …”
Get full text

A unique spumavirus Gag N-terminal domain with functional properties of orthoretroviral matrix and capsid. by David C Goldstone, Thomas G Flower, Neil J Ball, Marta Sanz-Ramos, Melvyn W Yap, Roksana W Ogrodowicz, Nicole Stanke, Juliane Reh, Dirk Lindemann, Jonathan P Stoye, Ian A Taylor

“…Although FV infection is apparently benign, trans-species zoonosis is commonplace and has resulted in the isolation of the Prototypic Foamy Virus (PFV) from human sources and the potential for germ-line transmission. Despite little sequence homology, FV and orthoretroviral Gag proteins perform equivalent functions, including genome packaging, virion assembly, trafficking and membrane targeting. …”
Get full text

A Modified NK Cell Degranulation Assay Applicable for Routine Evaluation of NK Cell Function by Snehal Shabrish, Maya Gupta, Manisha Madkaikar

Get full text

Granulocyte Colony Stimulating Factor (G‐CSF) and Olfactory Function—A Clinical Pilot Study by C. A. Hintschich, K. Resler, C. Brückner, A. Altundag, K. Trautmann, K. Hölig, F. Kroschinsky, M. Pieniak, T. Hummel

“…ABSTRACT Background Although the olfactory epithelium, including its neuronal cell line, has inherent regenerative potential, therapeutic options remain limited. …”
Get full text

Understanding functional abdominal pain disorders among children: a multidisciplinary expert consensus statement by Yvan Vandenplas, Andy Darma, Flavia Indrio, Marion Aw, Mario C. Vieira, Boosba Vivatvakin, Suporn Treepongkaruna, Sylvia Cruchet, Bhaswati C. Acharyya, Rodrigo Vázquez, Chun Yan Yeung, Pedro Gutiérrez

“…IntroductionFunctional abdominal pain disorders (FAPDs) are pediatric gastrointestinal conditions marked by chronic or recurrent abdominal pain without anatomical and/or biochemical abnormalities. …”
Get full text

Impact of rheumatoid factors on the function of therapeutic monoclonals specific for PD-1/PD-L1 by Barry D. Hock, Liping Goddard, Lachlan J. Dobson, Sean A. MacPherson, John L. O’Donnell, Judith L. McKenzie, Alexander D. McLellan

Get full text

Functional identification of saline-alkali stress enhancing gene GATL1 in apple (Malus halliana) by Xiu Wang, Juanli Li, Zhongxing Zhang, Yanxiu Wang

Get full text

Improving the drug delivery performance of ZIF-8 with amine functionalization as a 5-fluorouracil nanocarrier by Sahba Mirzanejad, Mojtaba Bagherzadeh, Arshad Bayrami, Hossein Daneshgar, Aida Bahrami, Majid Mahdavi

“…Abstract This study investigates the effect of amine functional groups in ZIF-8 metal–organic frameworks on the loading and release of 5-fluorouracil (5-FU). …”
Get full text

Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations. by Jonathan D Mosley, Sara L Van Driest, Peter E Weeke, Jessica T Delaney, Quinn S Wells, Lisa Bastarache, Dan M Roden, Josh C Denny

“…The coupling of electronic medical records (EMR) with genetic data has created the potential for implementing reverse genetic approaches in humans, whereby the function of a gene is inferred from the shared pattern of morbidity among homozygotes of a genetic variant. …”
Get full text

Decellularized liver scaffolds for constructing drug-metabolically functional ex vivo human liver models by Juan Liu, Ariel Hanson, Wenzhen Yin, Qiao Wu, Eliane Wauthier, Jinmei Diao, Timothy Dinh, Jeff Macdonald, Ruihong Li, Masahiko Terajima, Mitsuo Yamauchi, Ziye Chen, Praveen Sethupathy, Jiahong Dong, Lola M. Reid, Yunfang Wang

“…We have developed a bioengineered, perfused, organ-level human liver model that accurately replicates key liver functions, including metabolic activities, and protein synthesis, thus addressing some of the limitations associated with traditional liver monolayers, organoids, and matrix-embedded liver cells. …”
Get full text

CONCERNING THE USE OF INFORMATION AND COMMUNICATION TECHNOLOGIES BY THE SECRETARIAT OF THE CONSTITUTIONAL COURT OF UKRAINE IN PERFORMING ITS FUNCTIONS by Darya Barvitska

“…According to this plan, one of the proposed action is to support the efficient functioning of the Court and development of the constitutional justice. …”
Get full text

Kiperin Postbiotic Supplement-Enhanced Bacterial Supernatants Promote Fibroblast Function: Implications for Regenerative Medicine by Lutfiye Karcioglu Batur, Cuneyd Yavas, Yağmur Ekenoğlu Merdan, Ashabil Aygan

“…This study aimed to evaluate the effects of a postbiotic supplement (PS)—composed of inactivated strains of <i>Escherichia coli</i>, <i>Lacticaseibacillus rhamnosus</i>, and <i>Lactiplantibacillus plantarum</i>—on fibroblast function, particularly in the context of bacterial secretomes from common pathogenic strains. …”
Get full text

Functional roles of folic acid in alleviating dexamethasone‐induced fatty liver syndrome in laying hens by Xi Sun, Junjie Ma, Chaohui Wang, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu

Get full text

Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript. by Maurice A Canham, Alexei A Sharov, Minoru S H Ko, Joshua M Brickman

“…ES cells are defined as self-renewing, pluripotent cell lines derived from early embryos. Cultures of ES cells are also characterized by the expression of certain markers thought to represent the pluripotent state. …”
Get full text

Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation by Malene Malchus Fosse, Laura Rivera Méndez, Tania Rodríguez-Ramos, Brian Dixon, Henrik Sundh, Rolf Erik Olsen

“…Functional feed ingredients can enhance the fish gut integrity and immune resilience during challenging situations in the aquaculture industry. …”
Get full text