Ultrasonographic assessment of diaphragmatic excursion and its correlation with pulmonary function tests in pediatric cystic fibrosis by Eman Mahmoud Fouda, Neven Mahmoud Fouda, Marwa Ahmed Kamel

“…Conclusion Ultrasound is a safe, simple, and noninvasive bedside method that can help clinicians assess diaphragmatic excursion and thickness in pediatric cystic fibrosis patients and correlates with pulmonary function tests.…”
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Quality of life, symptom profile and clinical efficacy of second-line treatment with dasatinib in patients with imatinib-resistant or -intolerant chronic myeloid leukemia: results... by T. I. Ionova, T. P. Nikitina, E. G. Lomaia, G. B. Kuchma, E. R. Machyulaytene, E. I. Usacheva, T. V. Shnaider, A. Yu. Rodionova, K. A. Kurbatova

“…Significant improvement of physical functioning, role physical functioning, role emotional functioning, vitality and mental health as compared to base-line parameters was observed (p < 0.05). …”
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PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation by Mingming Cao, Yuzhen Tong, Qingguo Lv, Xiang Chen, Yang Long, Li Jiang, Jun Wan, Yuwei Zhang, Fang Zhang, Nanwei Tong

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Using a brain-like endothelial cell differentiation to characterize the CS79iBRCA-n2 BRCA1 mutated patient derived stem cell line by Natalie G. Alexander, Kylie A. Buchanan, Alexandra E. Meyer, Lauren M. Mitterway, Caroline O. Vanderburgh, Shreyas S. Rao, Shreyas S. Rao, Shreyas S. Rao, Brandon J. Kim, Brandon J. Kim, Brandon J. Kim, Brandon J. Kim, Brandon J. Kim

“…This patient-derived hiPSC line can be utilized to study BBB properties as after differentiation into brain-like endothelial cells (BECs), BECs derived from this line express BBB markers such as tight junction proteins, and functional efflux transporters. …”
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Brown alga Sargassum wightii derived bioactive compound as potential anti-cancerous agent and molecular docking insights on Hep-2, THP-1 and Cervical cancer cell lines by Sundaramoorthy Dhanasundaram, Pachiappan Perumal, Perumal Santhanam, Annamalai Aravinth, Chinnaperumal Kamaraj, Chinnasamy Ragavendran, Gholamreza Abdi

“…NMR spectral data verified the positions of hydroxyl and carbonyl functional groups. Naringenin exhibited strong antioxidant activity with a DPPH radical scavenging rate of 73.17 %. …”
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Determinants of virological failure among adults on first-line highly active antiretroviral therapy at public health facilities in Kombolcha town, Northeast, Ethiopia: a case–contr... by Habtamu Mengist Meshesha, Zelalem Mehari Nigussie, Anemaw Asrat, Kebadnew Mulatu

“…Objective To identify determinants of virological failure among HIV-infected adults on first-line highly active antiretroviral therapy at public health facilities in Kombolcha town, Northeast, Ethiopia, in 2019.Methods An unmatched case–control study was conducted from April to May 2019. …”
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PD-L1 pfeRNAs as blood-based predictors of treatment response of unresectable malignant pleural mesothelioma patients administered Durvalumab with cisplatin and pemetrexed as first... by Andrei Gurau, Suguru Yamauchi, Kaitlyn Ecoff, Kristen P. Rodgers, James R. Eshleman, Charles Conover Talbot Jr, Peng Huang, Joshua Choi, Patrick M. Forde, Valsamo Anagnostou, Malcolm Brock, Yuping Mei

“…However, the limited patient response to Durva-CP needs predictors to select optimal candidates and monitor the developed resistance. Protein functional effector sncRNA (pfeRNA) reveals a fundamental mechanism underlying the regulation of protein activity. …”
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Synthetic CB1 Cannabinoids Promote Tunneling Nanotube Communication, Cellular Migration, and Epithelial–Mesenchymal Transition in Pancreatic PANC-1 and Colorectal SW-620 Cancer Cel... by David A. Bunsick, Leili Baghaie, Yunfan Li, Abdulrahman M. Yaish, Emilyn B. Aucoin, Elizabeth Skapinker, Rashelle Aldbai, Myron R. Szewczuk

“…During this reprogramming process, cancer cells’ metabolism and other cellular activities are integrated and mutually regulated by tunneling nanotube communications to alter their specific metabolic functional drivers of tumor growth and progression. …”
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Gamma Knife stereotactic radiotherapy combined with tislelizumab as later-line therapy in pMMR/MSS/MSI-L metastatic colorectal cancer: a phase II trial analysis by Yiran Zhang, Hanyang Guan, Shijin Liu, Haoquan Li, Zili Bian, Jiashuai He, Zhan Zhao, Shenghui Qiu, Tianmu Mo, Xiangwei Zhang, Zuyang Chen, Hui Ding, Xiaoxu Zhao, Liang Wang, Yunlong Pan, Jinghua Pan

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Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development by Saman Hussain, Katherine Pinter, Mara Uhl, Hiu-Tung Wong, Katie S Kindt

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Comparative efficacy of tislelizumab plus lenvatinib and tislelizumab alone against advanced hepatocellular carcinoma after lenvatinib failure: a real-world study by Jiajin Yang, Qiuping Xu, Sihao Luo, Jianbing Wu

“…The incidence of AEs was comparable between the two groups. As a second-line treatment, the combination of tislelizumab and lenvatinib was well tolerated and associated with improved OS and PFS versus tislelizumab alone for patients with advanced HCC, particularly in those with Child–Pugh A liver function.…”
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Tomatine Improves Glucose Metabolism and Mitochondrial Respiration in Insulin-Resistant Hepatocyte Cell Lines AML12 and HepG2 via an AMP-Activated Protein Kinase-Dependent Pathway by Yu Geon Lee, Donghwan Kim

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Specifications and functional impact of a self-triggered grasp neuroprosthesis developed to restore prehension in hemiparetic post-stroke subjects by R. Le Guillou, J. Froger, M. Morin, M. Couderc, C. Cormier, C. Azevedo-Coste, D. Gasq

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Shell oscillations in symmetry energy by V. M. Kolomietz, A. I. Sanzhur

“…We observe the nonmonotonic (sawtooth) shape of the β-stability line given by the asymmetry parameter as a function of mass number. …”
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Retrotransposon life cycle and its impacts on cellular responses by Ahmad Luqman-Fatah, Kei Nishimori, Shota Amano, Yukiko Fumoto, Tomoichiro Miyoshi

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CYP1B1 Knockout in a Bovine Hepatocyte-like Cell Line (BFH12) Unveils Its Role in Liver Homeostasis and Aflatoxin B1-Induced Hepatotoxicity by Silvia Iori, Ludovica Montanucci, Caterina D’Onofrio, Maija Lahtela-Kakkonen, Lorena Lucatello, Anisa Bardhi, Andrea Barbarossa, Francesca Capolongo, Anna Zaghini, Marianna Pauletto, Mauro Dacasto, Mery Giantin

“…In this study, we generated a <i>CYP1B1</i> knockout (<i>CYP1B1</i>^KO) bovine hepatocyte-like cell line to indirectly investigate its role in liver function. …”
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A novel scavenger receptor 5-based antibiotic-independent selection method for generation of stable recombinant protein-producing mammalian cell lines especially suitable for prote... by Juha Risto Matias Ojala, Timo Pikkarainen, Anna Domogatskaya, Karl Tryggvason, Sergey Rodin

“…The establishment of stable recombinant protein-producing mammalian cell lines is an expensive, time-consuming, tedious procedure. …”
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Possibility of using remote sensing data for glaciological calculations and monitoring by V. G. Konovalov, V. A. Rudakov

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Antiproliferative Effects of Methanolic Extracts of Cryptocarya concinna Hance Roots on Oral Cancer Ca9-22 and CAL 27 Cell Lines Involving Apoptosis, ROS Induction, and Mitochondri... by Hurng-Wern Huang, Yi-An Chung, Hsun-Shuo Chang, Jen-Yang Tang, Ih-Sheng Chen, Hsueh-Wei Chang

“…In this study, we firstly used the methanolic extracts of C. concinna Hance roots (MECCrt) to evaluate its potential function in antioral cancer bioactivity. We found that MECCrt significantly reduced cell viability of two oral cancer Ca9-22 and CAL 27 cell lines in dose-responsive manners (P<0.01). …”
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High-content analysis identified synergistic drug interactions between INK128, an mTOR inhibitor, and HDAC inhibitors in a non-small cell lung cancer cell line by Sijiao Wang, Juliano Oliveira-Silveira, Gang Fang, Jungseog Kang

“…Optical high-content analysis of cellular responses has recently attracted much interest in the field of drug discovery, functional genomics, and toxicology. Here, we adopted a similar approach to study combinatorial drug responses. …”
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