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  1. 1021
  2. 1022
  3. 1023

    Development and evaluation of an instrument to examine young children’s knowledge of the biological concept of structure and function by Pamela Flores, William J. Boone, Birgit J. Neuhaus

    Published 2025-04-01
    “…One important line of inquiry pursued by researchers has focused on the development of instruments to assess students’ knowledge of different scientific concepts. …”
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    Article
  4. 1024

    PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y Abramov, Erik A Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R Duchen, David Latchman, Sarah J Tabrizi, Nicholas W Wood

    Published 2008-06-01
    “…In order to investigate the role of PINK1 in Parkinson's disease, we studied PINK1 loss of function in human and primary mouse neurons. Using RNAi, we created stable PINK1 knockdown in human dopaminergic neurons differentiated from foetal ventral mesencephalon stem cells, as well as in an immortalised human neuroblastoma cell line. …”
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    Article
  5. 1025
  6. 1026

    Antioxidant activity and in vitro fluorescence imaging application of N-, O- functionalized carbon dots by Adina Coroaba, Maurusa Ignat, Oana-Elena Carp, Corneliu S. Stan, Silviu I. Filipiuc, Cristina M. Uritu, Natalia Simionescu, Narcisa-Laura Marangoci, Mariana Pinteala, Conchi O. Ania

    Published 2025-07-01
    “…Abstract Nanomaterials with dual-functions integrating diagnostic and therapeutic abilities have attracted the interest in biomedical applications, and low-dimensional carbon dots have shown their potentialities in the field owing to their versatile optical and physicochemical properties. …”
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    Article
  7. 1027

    PI3-kinase has multiple functions in asexual blood stages of Plasmodium falciparum by Reem Al Monla, Maria Penzo, Alice Vallentin, Rakhee Lohia, Jeremy Vincent, Laurence Berry, Ana Rita Gomes, Rachel Cerdan, Kai Wengelnik

    Published 2025-05-01
    “…Here we dissect the functions of PfPI3-kinase by inducible deletion of its gene using the loxP-DiCre system and find that PfPI3-kinase is essential for parasite survival. …”
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    Article
  8. 1028

    Functional Identification and Transcriptional Activity Analysis of <i>Dryopteris fragrans HMGR</i> Gene by Meng Sun, Qian Ma, Xueqi Wang, Jialiang Guo, Jiaxuan Wang, Dongrui Zhang, Kirill Tkachenko, Wenzhong Wang, Ying Chang

    Published 2025-07-01
    “…Although HMGR plays a crucial role in terpenoid biosynthesis, its functional characteristics in <i>D. fragrans</i> and its involvement in stress responses remain unclear. …”
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    Article
  9. 1029

    Oxidative stress biomarkers for assessing the synergistic toxicity of emamectin benzoate and cyantraniliprole on liver function by Yaxuan Zhang, Yuxin Xiang, Zhiyong Cao, Kaijie Dai, Shuyan Gui, Yuying Liu, Ziqi Liu, Yanhong Shi, Haiqun Cao, Jinjing Xiao

    Published 2025-05-01
    “…We observed a remarkable increase in serum biochemical parameters related to rat liver function when rat liver was exposed to the binary mixture of emamectin benzoate and cyantraniliprole. …”
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    Article
  10. 1030

    Aquaporin 5 polymorphisms and rate of lung function decline in chronic obstructive pulmonary disease. by Nadia N Hansel, Venkataramana Sidhaye, Nicholas M Rafaels, Li Gao, Peisong Gao, Renaldo Williams, John E Connett, Terri H Beaty, Rasika A Mathias, Robert A Wise, Landon S King, Kathleen C Barnes

    Published 2010-12-01
    “…<h4>Rationale</h4>Aquaporin-5 (AQP5) can cause mucus overproduction and lower lung function. Genetic variants in the AQP5 gene might be associated with rate of lung function decline in chronic obstructive pulmonary disease (COPD).…”
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    Article
  11. 1031

    The Value of Ketone Bodies in the Evaluation of Kidney Function in Patients with Type 2 Diabetes Mellitus by Yimei Li, Yongze Zhang, Ximei Shen, Fengying Zhao, Sunjie Yan

    Published 2021-01-01
    “…This study is aimed at investigating the association between different levels of KBs and kidney function in patients with type 2 diabetes mellitus (T2DM). …”
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    Article
  12. 1032

    Structural function of multidrug-resistant Salmonella carrying mcr-1 gene in colistin resistance by Md. Mukter Hossain, Riazul Islam Riad, Md. Mashfiq Hossain Khadem, Ruhena Begum, Md. Shoriful Alam Sumon, Ho-Seong Cho, Md. Mahfujur Rahman, Md Bashir Uddin

    Published 2025-06-01
    “…Furthermore, in-silico functional studies were conducted to explore the genetic relationships and phenotypic correlations among these colistin-resistant isolates. …”
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    Article
  13. 1033

    Current Principles of Functional Gait Rehabilitation in Adults with Foot Drop after a Stroke by Alexandra Ionela PRALA, Luminita Ionela GEORGESCU, Mirela Carmen DAN

    Published 2024-12-01
    “…Introduction: Stroke causes muscle weakness and atrophy, which leads to functional and mobility disorders. Muscle weakness of the lower limb is closely related to decreased gait performance, endurance and speed. …”
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  14. 1034

    The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function. by Weili Cai, Youheng Wei, Michal Jarnik, John Reich, Mary A Lilly

    Published 2016-05-01
    “…Notably, we find that two additional members of the GATOR2 complex, Mio and Seh1, also have a TORC1 independent role in the regulation of lysosome function. These findings represent a surprising and previously unrecognized function of GATOR2 complex components in the regulation of lysosomes. …”
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    Article
  15. 1035

    Stable minichromosome and functional neocentromere derived from rye 7R chromosome arm by Zongxiang Tang, Qian Liu, Zijin Pan, Chang Liu, Jieran Dong, Fangpu Han, Shulan Fu

    Published 2024-12-01
    “…We theorize that R-loops and transposable element might be involved in the positioning of CENH3 nucleosomes in a functional neocentromere.…”
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    Article
  16. 1036
  17. 1037

    Examination of the functions and mechanism of KCP in mediating paclitaxel resistance in cervical squamous carcinoma cells by Yue He, Jian-Qing Xu, Jing-Jing Zhang, Zhen-You Liu, Chen Ji, Yang Liu, Yun-Fan Wang, Ming Wang, Yu-Mei Wu, Yan Wang

    Published 2025-04-01
    “…Key cell functions were assessed by colony formation assay, measurement of cell proliferation by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and FACS-based detection of apoptosis. …”
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    Article
  18. 1038

    The CaSBP11 gene functions as a negative regulator in pepper drought stress by Huai-Xia Zhang, Yuan Zhang, Bo-Wen Zhang, Fei-Fei Pan

    Published 2025-04-01
    “…Subsequently, we employed virus-induced gene silencing, overexpression, and protein interaction experiments to investigate the function of CaSBP11 under drought stress. Our results revealed that drought conditions significantly upregulated CaSBP11 expression, whereas ABA treatment suppressed it. …”
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    Article
  19. 1039

    Study of the functional diagram and algorithm of tracking system for electrodynamic braking of DC electric train by V. A. Baranov, I. P. Vikulov, A. A. Kiselev, A. S. Maznev

    Published 2020-05-01
    “…Characteristics of the pulse braking resistance controller for the current settings of the 250 and 350 A armature were calculated. Functional diagram of the tracking system with a description of its individual elements is developed. …”
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    Article
  20. 1040

    Effect of Polydopamine Nanoparticle-Induced Surface Modification on Demineralized Dentin for Enhanced Functional Remineralization by Manavalan Madhana Madhubala, Sekar Mahalaxmi

    Published 2024-12-01
    “…Conclusion: Dentin remineralization is more strongly facilitated by nanometric PDA than PDA, which has an enhanced functional remineralization effect.…”
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