High‐resolution mapping of cancer cell networks using co‐functional interactions by Evan A Boyle, Jonathan K Pritchard, William J Greenleaf

“…Lastly, we employed a gene community detection approach to implicate core genes for cancer growth and compress signal from functionally related genes in the same community into a single score. …”
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Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity. by E J Brace, Kow Essuman, Xianrong Mao, John Palucki, Yo Sasaki, Jeff Milbrandt, Aaron DiAntonio

“…We developed transgenic Drosophila lines that express SARM1 variants with normal, deficient, and enhanced NADase activity and tested their function in NMJ development. …”
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Dynamic human liver proteome atlas reveals functional insights into disease pathways by Lili Niu, Philipp E Geyer, Rajat Gupta, Alberto Santos, Florian Meier, Sophia Doll, Nicolai J Wewer Albrechtsen, Sabine Klein, Cristina Ortiz, Frank E Uschner, Robert Schierwagen, Jonel Trebicka, Matthias Mann

“…Using primary cell cultures, we capture dynamic proteome remodeling from tissue states to cell line states, providing useful information for biological or pharmaceutical research. …”
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Late-stage functionalization of anticancer agent Daniquidone and the in vitro anticancer activities of the derivatives by Geshuyi Chen, Yechun Zeng, Xin Chen, Zhe Chang, Pei Yuan, Haijia Chen, Yongxiu Yang, Xiaolei Liang, Kun Yue, Depeng Zhao

“…Nitrogen heterocycles play an important role in drugs and natural products. C-H late-stage functionalization (LSF) of N-heterocycles might provide a direct route to construct diversified analogues with potential pharmaceutical activities. …”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

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An efficient quantum algorithm for ab initio approximations of non-linear response functions by Tyler Kharazi, Torin F. Stetina, Liwen Ko, Guang Hao Low, K. Birgitta Whaley

“…When applied to the electronic structure Hamiltonian with double factorized representation, each significant spectral line can be approximated to a width of ±γ, and to a height of ±ϵ with $$O\left({N}^{6}{\eta }^{2}{\gamma }^{-1}{\epsilon }^{-1}\log (1/\epsilon )\right)$$ O N 6 η 2 γ − 1 ϵ − 1 log ( 1 / ϵ ) queries to the block encoding of the unperturbed electronic structure Hamiltonian for η electrons over N basis functions. …”
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Causality-aware graph neural networks for functional stratification and phenotype prediction at scale by Charalampos P. Triantafyllidis, Ricardo Aguas

“…Abstract We employ a computational framework that integrates mathematical programming and Graph Neural Networks (GNNs) to elucidate functional phenotypic heterogeneity in disease by classifying entire pathways under various conditions of interest. …”
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Implementation of multi-UAV communication relay function based on mobile telecommunication technology by Wen-Chung Tsai, Nien-Ting Huang

“…The proposed Layer-2 MAC design is implemented within a System on a Programmable Chip, integrating both BS and UE functionalities into a unified platform. This modular approach allows future updates to BS and UE designs in line with evolving 3GPP standards by modifying only the relevant Intellectual Property (IP) components. …”
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Individual objective versus subjective fixation disparity as a function of forced vergence. by Wolfgang Jaschinski

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Surface-functionalized design of blood-contacting biomaterials for preventing coagulation and promoting hemostasis by Yi Wang, Weijie Zhai, Shujie Cheng, Jinghua Li, Hongyu Zhang

“…Abstract The anticoagulation and hemostatic properties of blood-contacting materials are opposite lines of research, but their realization mechanisms are inspired by each other. …”
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Function of vasohibin-2 and the mechanism of alternative splicing in triple-negative breast cancer by WANG Wei, WANG Hongli, ALIBIYATI·i Ain, YILIYAER· Rousu, NUER AYI, YANG Liang

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Left-right function of dmrt2 genes is not conserved between zebrafish and mouse. by Raquel Lourenço, Susana S Lopes, Leonor Saúde

“…On the basis of evolutionary sub-functionalization and neo-functionalization theories we discuss this absence of functional conservation.…”
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Early Aggressive Immunotherapy Improves Functional Outcome in Chronic Immune Sensory Polyradiculopathy by Jasmine Shimin Koh, James Wei Min Tung, Genevieve Lynn Yu Tan-Yu, Thirugnanam Umapathi

“…We urge physicians to recognize this uncommon neurologic cause of sensory ataxia where early aggressive treatment is crucial for better functional outcomes.…”
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On the Convergence of Normal and Curvature Calculations with the Height Function Method for Two-Phase Flow by Antonio Cervone, Sandro Manservisi, Jieyun Pan, Ruben Scardovelli, Stéphane Zaleski

“…The volume-of-fluid (VOF) method is widely used for multiphase flow simulations, where the VOF function implicitly represents the interface through the volume fraction field. …”
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Ghrelin’s Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality by Antonia Diaz-Ganete, Gloria Baena-Nieto, Isabel M. Lomas-Romero, Jose Francisco Lopez-Acosta, Irene Cozar-Castellano, Francisco Medina, Carmen Segundo, Alfonso M. Lechuga-Sancho

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Glucose-functionalized redox-responsive dihydroartemisinin prodrug nanosystem for targeted malaria therapy by Rongrong Wang, Jiaqi Yang, Jihong Qiang, Qingxia Li, Geng Wang, Canqi Ping, Kesheng Liu, Ruili Wang, Bin Zheng, Guolian Ren, Shuqiu Zhang

“…Artemisinins are the first-line antimalarial drugs. However, their therapeutic efficacy is significantly limited by poor solubility and short biological half-life. …”
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Sabāhi’s Techniques of Depicting Semantic and Inspirational Functions and Intentions of Verses from Qur’an by Maryam Baghi

“…What are the semantic functions and intentions related to those techniques in his poetry? …”
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Differences in the functional use of two migratory stopovers by humpback whales (Megaptera novaeangliae). by Raphael Mayaud, Joshua N Smith, David Peel, Craig Wilson, Wally Franklin, Tim Stevens, Susan Bengtson Nash

“…Moreton Bay is a newly identified migratory stopover for Australia's east coast humpback whale population. Understanding the functional roles of stopovers is essential for a holistic understanding of population dynamics and connectivity. …”
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Longwall top coal caving technological process in the notation of the system-functional approach by Cherkasov P.V.

“…Based on the conducted system-functional analysis, a stand structure has been developed for measuring the volume of rock mass produced using machine vision and projection of a grid of laser lines, which makes it possible to measure the volume of rock mass in the boundary conditions of illumination, humidity and dustiness, and It is also necessary to determine the influence of environmental factors on the quality of recognition of a laser grid by a machine vision system…”
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Three-dimensional combined inversion method of the MT and Network-MT response functions by Yoshiya Usui, Makoto Uyeshima

“…One of the most effective approaches for robustly estimating the resistivity structure with correction of galvanic distortion is using the response function of the Network-MT method, which uses metallic telephone lines to measure the electric field. …”
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