Model systems and unique biological features of high and low-grade colorectal cancer (CRC) revealed by xenografting 84 human CRC cell lines by Ian Y. Luk, Jennifer K. Mooi, Dmitri Mouradov, Tao Tan, Cameron M. Scott, Fiona Chionh, Laura J. Jenkins, Camilla M. Reehorst, Rebecca Nightingale, Peter Savas, Janson WT Tse, Rebekah LI Crake, Eduard Batlle, Diego Arango, Higino Dopeso, Peter Gibbs, Niall C. Tebbutt, Rod B. Luwor, Andrew M. Scott, Faiza Basheer, Amardeep S. Dhillon, Nicholas J. Clemons, David S. Williams, Ron Firestein, Oliver M. Sieber, John M. Mariadason

“…Importantly, CRC cell line-derived transcriptional profiles of differentiation grade were reflected in LG and HG patient-derived tumour organoids and primary CRCs, revealing cell lines accurately model differentiation grade. …”
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Green synthesis of silver nanoparticles from Cuscuta epithymum extract, evaluation of antibacterial, antioxidant activity, cytotoxic effect on MCF-7 cell line by M. Fereydani, A. Jalalian, N. Saber

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Robustness of viral load over CD4 cell count in measuring the quality of life of people with HIV at second line regimen in Amhara region by Awoke Seyoum Tegegne

“…Among the predictors for quality of life, age of patients, level of CD4 cell count while transferring to second-line regimen, sex of patients, social discrimination, level of education of patients, functional status, adherence level, disclosure status of the disease, mental depression, existence of opportunistic infections and residence area had significant effect on the variable of interest (quality of life). …”
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Reduced Cish expression by siRNA knockdown in Natural Killer cells promotes anti-tumor effects against gastric cancer cell lines by Sahar Khojastehpour, Azarmidokht Aminazad, Shahrokh Abdolahi, Shirin Tavakoli, Maryam Samareh-Salavati, Nasrin Momeni, Mohammad Vaezi, Mohammad Ahmadvand

“…Abstract Improving immune cell functions in tumors remains a main challenge in cancer immunotherapy. …”
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Genetic basis of the mucilage secretion ability associated with nitrogen fixation from aerial roots of maize inbred lines under low nitrogen conditions by Bowen Zhao, Xin Hou, Zhongliang Yu, Ronghui Zhang, Huixin Teng, Ziqiong Yang, Jianju He, Huijuan Wang, Zhihao Song, Jiankang Zheng, Bolin Song, Shiwei Ma, Doudou Sun, Xiaowei Fan, Jingyang Gao, Zijian Zhou, Jiafa Chen, Pei Jing, Jianyu Wu

“…Recent studies have shown that mucilage secretion from aerial roots is an essential feature of modern maize inbred lines, with some retaining the nitrogen-fixing capabilities of ancient landraces. …”
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Characterization of silver nanoparticles (AgNPs) synthesized using polyphenolic compounds from Phyllanthus emblica L. and their impact on cytotoxicity in human cell lines by Azhagu Madhavan Sivalingam, Arjun Pandian

“…Various characterization techniques were employed to assess the anticancer properties against the human MCF-7 Breast Cancer Cell Line. This study in UV‒visible spectroscopy AgNPs detected at 436 nm, FT-IR analysis indicated the presence of specific functional groups with high peak intensity at 3105 cm−1. …”
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Human malignant ovarian germ cell tumor cell lines derived from peritoneal cytology retrieving from circulating tumor cell system by Jie Yang, Xinyue Zhang, Jie Tang, Xiaolei Fu, Qiong Wu, Hong Li, Rui Chen, Jiaxin Yang

“…Establishing personalized permanent tumor cell lines is crucial for understanding tumor behavior and optimizing precision treatment for these patients. …”
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Evaluation Methods for the Human–Land Coupling Coordination Relationship in a Metro Station Area: A Case Study of Chengdu Metro Line 1 by Zhiyue Qiu, Shirui Wen, Hong Yuan, Ziyi Liu, Yao Wei, Siqi Yanling, Runlong Dai, Xiang Li, Yuxin Gu

“…Finally, some improvement strategies are put forward, such as optimizing the network layout, building multi-level centers, strengthening functional connections, and enhancing the development intensity. …”
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Haplotype Analysis of the GL7/GW7/SLG7 Gene and Its Application in Improving the Grain Quality of Three-Line Hybrid Rice by Duo Xia, Peizhou Xu, Shuqin Zheng, Le Xue, Yuejiao Yin, Zhuchen Yao, Sikai Ding, Yusen Lai, Yipei Wang, Xiaoding Ma, Xianjun Wu, Hao Zhou

“…Yuehesimiao (YHSM) and Yixiang 1 A (YX1A) are widely applicated XI restorer line and sterile line in three-line hybrids. The improved hybrid YX1A GL7 /YHSM GL7 exhibited longer grain, higher ratio of grain length-to-width and larger rate of head rice, but lower chalkiness rate and degree than that of any other hybrids and both parents. …”
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Over-expression analysis of TaDWF4˗4B in mutant wheat lines identifies a candidate regulator of heat stress tolerance by Liaqat Shah, Muhammad Saeed, Muhammad Ibrahim, Waqas Ahmad, Abdul Rahman Umar, Ayan Sohail, Hongqi Si

“…Among them, TaDWF4˗4B showed highest expression under heat stress condition and selected for further functional analysis. Overexpression of TaDWF4˗4B in the wheat line ESWYT-4 enhanced heat tolerance. …”
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Structural and Functional Rearrangement of Great Arterial Vessels in the Late Postresuscitative Period by I. V. Mukhina, R. S. Kulikov, Ye. I. Yakovleva, N. N. Andreyeva, N. N. Prodanets, L. B. Snopova, M. L. Bugrova

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Technical solutions for the transmission of electricity at high voltage in arctic conditions by Varivodov V.N., Kovalev D.I., Golubev D.V., Elfimov S.A., Zhulikov S.S.

“…Within the framework of this strategy, it is necessary to develop and implement engineering and technical solutions for the transmission of electric power that ensure the stable functioning of the infrastructure in extreme climatic conditions. …”
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Integrated functional, gene expression and genomic analysis for the identification of cancer targets. by Elizabeth Iorns, Christopher J Lord, Anita Grigoriadis, Sarah McDonald, Kerry Fenwick, Alan Mackay, Charles A Mein, Rachael Natrajan, Kay Savage, Narinder Tamber, Jorge S Reis-Filho, Nicholas C Turner, Alan Ashworth

“…We combined our functional RNAi approach with gene expression and genomic analysis, allowing the identification of several novel kinases, including WEE1, that are essential for viability only in cell lines that have an elevated level of expression of this kinase. …”
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Function of a novel human gene TOX promoting cell proliferation by DENG Weiwei, LI Jing, GAO Peng, HAO Dongxia, ZHANG Lu, SHI Taiping, WANG Ying

“…RT-PCR analysis revealed that TOX was highly expressed in leukemia cell lines Jurkat and Raji, but was not detected in some tumor cell lines A549, H1299, H520. …”
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A time for sex: circadian regulation of mammalian sexual and reproductive function by Sydney Aten, Oscar Ramirez-Plascencia, Chiara Blake, Chiara Blake, Gabriel Holder, Gabriel Holder, Emma Fishbein, Emma Fishbein, Adam Vieth, Adam Vieth, Arman Zarghani-Shiraz, Arman Zarghani-Shiraz, Evan Keister, Evan Keister, Shivani Howe, Shivani Howe, Ashley Appo, Ashley Appo, Beatrice Palmer, Carrie E. Mahoney

“…Evidence supporting the importance of proper clock function on fertility comes from several lines of work demonstrating that misalignment of biological rhythms or disrupted function of the body’s master clock, such as occurs from repeated shift work or chronic jet lag, negatively impacts reproduction by interfering with both male and female fertility. …”
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Experimental study of Rac1 regulating osteoclast function in hypoxic environment by GU Jiahong, TIAN Yuanye, KANG Feiwu

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All-Passive Optical Fiber Sensor Network With Self-Healing Functionality by Ching-Hung Chang, Dong-Yi Lu, Wei-Hung Lin

“…An all-passive optical fiber sensor network is proposed based on a novel single-line bidirectional optical add-drop multiplexer (SBOADM). …”
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Neonatal Natural Killer Cell Function: Relevance to Antiviral Immune Defense by Yen-Chang Lee, Syh-Jae Lin

“…This review updates phenotypic and functional deficiencies of neonatal cells compared to their adult counterparts and their clinical implications.…”
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Rehabilitation coordinator – managers’ experiences of a new function in health care by Catharina Strid, Rosie Benner, Ronja Stefansdotter, Kjerstin Stigmar

“…Neither has the role of the manager, who has significant impact on the implementation and support of a new function. This study aimed to explore how first line managers’, who employed a rehabilitation coordinator that had completed a one-year specialized study program, perceived, and experience the function rehabilitation coordinator. …”
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Novel function of TREK-1 in regulating adipocyte differentiation and lipid accumulation by Ajung Kim, Seoyeong Jung, Yongeun Kim, Jonghoon Jung, Soomin Lee, Hojin Lee, Min Jung Kim, Jae-Yong Park, Eun Mi Hwang, Jaekwang Lee

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