Endothelial cells nurture stem cell-like characteristics of osteosarcoma cells in a perivascular niche by CXCL12/CXCR4 pathway by CAO Ya, LIU Yang, WANG Yang

“…Methods‍　‍A co-culture model was established in vitro using SV40T- human umbilical vein endothelial cells (HUVEC-T1) and osteosarcoma stem cells (OSCs) derived from the human osteosarcoma cell line 143B. Thus, there were 2 groups of cells, OSCs and co-cultured OSCs. …”
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Impact of diverse irrigation water sources on olive oil quality and its physicochemical, fatty acids, antioxidant, and antibacterial properties by Noureddine Benguennouna, Djilali Benabdelmoumene, Said Dahmouni, Zineb Bengharbi, Mohamed Bouzouina, Wasim S. M. Qadi, Esraa Adnan Dawoud Dawoud, Ebtesam Al-Olayan, Andres Moreno, Ahmed Mediani

“…These findings are relevant to water-scarce Mediterranean and arid regions, informing sustainable irrigation strategies in line with global climate-resilient agriculture policies.…”
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Methicillin‐resistant Staphylococcus aureus and Pseudomonas aeruginosa community acquired pneumonia: Prevalence and locally derived risk factors in a single hospital system by Bradley W. Frazee, Amarinder Singh, Matt Labreche, Partow Imani, Kevin Ha, Jonathan Furszyfer Del Rio, Eugene Kreys, Robert Mccabe

“…Challenges included determining the suspected infection type in patients admitted simply for “sepsis”; interpreting dictated radiology reports; determining functional status, presence of indwelling lines and tubes, and long‐term care facility residence from the electronic health record; and correctly attributing culture results to pneumonia. …”
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Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing by Tzu-Hsuan Chang, Yamel Cardona Gloria, Margareta J. Hellmann, Timmy Richardo, Carsten Leo Greve, Didier Le Roy, Thierry Roger, Francesca Bork, Stefanie Bugl, Johanna Jakob, Johannes Sonnberger, Lydia Kasper, Bernhard Hube, Bernhard Hube, Stefan Pusch, Neil A. R. Gow, Morten Sørlie, Anne Tøndervik, Bruno M. Moerschbacher, Alexander N. R. Weber, Alexander N. R. Weber, Alexander N. R. Weber, Alexander N. R. Weber

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Falls prevention interventions for community-dwelling older adults: systematic review and meta-analysis of benefits, harms, and patient values and preferences by Jennifer Pillay, Lindsay A. Gaudet, Sabrina Saba, Ben Vandermeer, Ashiqur Rahman Ashiq, Aireen Wingert, Lisa Hartling

“…Fractures are probably more important than either falls (0.09 over 12 months) or functional status (0.12). Functional status may be somewhat more important than falls. …”
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Efficient delivery of anlotinib and radioiodine by long circulating nano-capsules for active enhanced suppression of anaplastic thyroid carcinoma by Linlin Zhang, Chuanying Zhu, Shuo Huang, Miaomiao Xu, Chao Li, Hongliang Fu, Yafu Yin, Sheng Liang, Hui Wang, Zhilei Cui, Lei Huang

“…The nanoparticles could actively target tumor surface with anlotinib exhibiting enhanced radio-sensitization effects by functionally upregulating P53 and Bax. In vivo SPECT/CT imaging showed that the concentration of Anlotinib-nBSA-125I in tumors peaked at 24 h, and the intense signal persisted for at least one week. …”
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Actitudes hacia la diversidad sexual en el deporte en estudiantes de educación secundaria (Secondary Education Students’ Attitudes toward Sexual Diversity in Sport) by Alejandro Ramírez-Díaz, Ruth Cabeza-Ruiz

“…Therefore, it is necessary to make use of the healthy educational, social, cultural, and psychological functions that physical-sports activities can play towards people. …”
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Nuclear factor erythroid 2-related factor 1 regulates the expression of proteasomal genes in ketotic cows and protects mammary cells against free fatty acid–induced endoplasmic ret... by Taiyu Shen, Shijie Xia, Muhammad Usman, Xinyi Xu, Juan J. Loor, Chuang Xu

“…In nonruminants, loss of nuclear factor erythroid 2-related factor 1 (NFE2L1) results in ER stress. The physiological functions and molecular mechanisms controlled by NFE2L1 in bovine mammary tissue are poorly understood. …”
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CALL FOR PAPERSFOR THE SPECIAL ISSUE OF Zeszyty Teoretyczne Rachunkowości (ZTR – The Theoretical Journal of Accounting) in 2026

“…We particularly welcome research that proposes new models for managerial dashboards tailored to diverse user needs – executives, sustainability officers, and operational managers – along with the metrics that should populate these tools to satisfy the expanded mission of accounting.Join us in reimagining the frontiers of accounting in line with its newly defined moral, social, and technical imperatives.Suggested topicsWe encourage authors to prepare and submit articles that focus on the transition in managerial and financial accounting required by accounting’s expanded horizons. …”
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Human adenovirus type 7 (HAdV-7) infection induces pulmonary vascular endothelial injury through the activation of endothelial autophagy by Zhihe Chen, Zhongying Yang, Lifen Rao, Changgen Li, Na Zang, Enmei Liu

“…Methods The human lung microvascular endothelial cell line-5a and human CD46 mice were used for in vitro and in vivo experiments, respectively. …”
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The crucial role of neutrophil extracellular traps and IL-17 signaling in indomethacin-induced gastric injury in mice by Yujun Hou, Wen Wang, Jiangnan Ye, Luqiang Sun, Siyuan Zhou, Qianhua Zheng, Yunzhou Shi, Ying Chen, Junpeng Yao, Lu Wang, Xiangyun Yan, Renhong Wan, Shuai Chen, Ying Li

“…A mouse model of gastric injury was established using Indomethacin, followed by proteomic analysis (raw data are available via ProteomeXchange with identifier PXD058482). GO functional annotations and KEGG pathway enrichment analysis were conducted on significant differential proteins. …”
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Bladder cancer microbiome and its association with chemoresponse by Rashida Ginwala, Laura Bukavina, Laura Bukavina, Mohit Sindhani, Erika Nachman, Erika Nachman, Suraj Peri, Jodie Franklin, John Drevik, Sarah Christianson, Daniel M. Geynisman, Alexander Kutikov, Philip H. Abbosh, Philip H. Abbosh

“…Lastly, urine from bladder cancer patients harbored abundant Gammaproteobacteria, which in cell culture experiments, detoxified gemcitabine, a commonly used therapy in bladder cancer.ConclusionsIn summary, we identify many new relationships between the microbiome and bladder cancer that are clinically relevant and lay the groundwork important functional studies in the future.…”
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Sequence, characterization and pharmacological analyses of the adipokinetic hormone receptor in the stick insect, Carausius morosus by Gerd Gäde, Jinghan Tan, Salwa Afifi, Jean-Paul V. Paluzzi, Graham E. Jackson, Heather G. Marco

“…The resulting Carmo-AKHR was then expressed in a mammalian cell line where it could couple with a Gq protein to mediate calcium mobilization in vitro and cause bioluminescence when activated by a ligand. …”
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THE PREHISTORY OF THE MAGIC OF SCREENS. MOTIVES FROM THE “ILLIAD” AND THE “ODYSSEY” / ПРЕДЫСТОРИЯ ВОЛШЕБСТВА ЭКРАНОВ. МОТИВЫ «ИЛИАДЫ» И «ОДИССЕИ»... by SALNIKOVA EKATERINA V. / САЛЬНИКОВА ЕКАТЕРИНА ВИКТОРОВНА

“…The wall built by the Achaeans functions as another platitude of the screen. It also presents a kind of decoration, a background against which the battle scenes unfold. …”
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Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption by Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray

“…Here, we investigated the causes and consequences of downregulated miR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p levels in malignant GCTs regardless of age, site, or subtype. …”
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Dermatoglifia y Somatotipo en Jugadores de Voleibol del Departamento del Huila en los XX Juegos Deportivos Nacionales Colombia (Dermatoglyphia and Somatotype in Volleyball Players... by Oscar Alfredo Montenegro Arjona, Oscar Leonardo Cordoba Urriago, Angie Carolina Calderón Sterling, Cristian Javier Mendez Parra, Gian Carlos Tovar Osso

“…The team presents a mesomorph-endomorphic somatotype and a dermatoglyphic profile of loops (68.46% ± 17.4), whorl (28.46% ± 18.64), and arches (3.08% ± 6.30) with mean values in the delta index count (12.54 ± 2.18) and sum of the full quantity of lines (130.38 ± 46.00). The volleyball team is classified in class IV of the dermatoglyphic and somatic functional index; where, the low presence of arches and a higher count of loops are typical of sports due to the dominance of power, coordination, and endurance. …”
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Neuroprotective Activity of 5-ethoxy-2-ethylthiobenzimidazole (Etomerzol) and 2-ethylthiobenzimidazole (Bemitil) in a Model of Middle Cerebral Artery Occlusion by E. Yu. Zavarina, E. K. Krasova, I. A. Titovich, A. N. Kimaev

“…The introduction of bemitil, etomerzol and DMF significantly reduced the neurological deficit 24 hours after OSMA and improved the psycho-functional state on the 7th day. Thus, in the etomerzol group on the first day after surgery, the neurological deficit was reduced by 1.9 times (p < 0.05), and by 3 and 2.0 times (p < 0.05) compared with the control group. …”
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Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor mi... by Sang Hoon Lee, Jonghwa Won, Sora Kim, Wonjun Son, Yangsoon Lee, Yelim Park, Kyeong-Su Park, Hyunseong Youn, Arim Seo, Byungje Sung

“…This study investigated whether ABL112, an Fc-competent bispecific antibody targeting TIGIT and 4-1BB (TIGITx4-1BB), would enhance antitumor activity via Fcγ receptor (FcγR)-mediated macrophage activation and antibody-dependent cell-mediated functions.Methods TIGIT-dependent 4-1BB activation and TIGIT-blocking activity were assessed using reporter Jurkat T cell lines expressing 4-1BB and TIGIT, respectively. …”
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A novel telomere-associated genes signature for the prediction of prognosis and treatment responsiveness of hepatocellular carcinoma by Kuo Kang, Hui Nie, Weilu Kuang, Xuanxuan Li, Yangying Zhou

“…The expression and functional significance of ASF1A in HCC cell lines were investigated through colony formation assays, Transwell migration assays, and wound healing experiments. …”
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Reversing cardiac hypertrophy and heart failure using a cardiac targeting peptide linked to miRNA106a by Ming Lu, Siqi Cai, Kyle Korolowicz, Claire Deng, Kaan Taskintuna, Gerard Ahern, Raymond B. Yurko, Kazi R. Islam, Bryn Schoonover, Jack B. Lopuszynski, Hongkun Wang, Maliha Zahid, G. Ian Gallicano

“…., hypertension, diabetes mellitus, coronary artery disease, etc.) lead to structural and functional changes in cardiomyocytes, resulting in HF. …”
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