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7781
The Aporia of Reality/Imagination: Uncertainty in Selected Iranian Monodramas and Surrealist Dramas
Published 2025-06-01“…This research explores how the aporia of reality and imagination functions as a rhetorical tool that renders drama as self-deconstructive. …”
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7782
A ROLE OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES M49-16 IN PROMOTING INFECTION AND INHIBITION OF ENDOTHELIAL CELL PROLIFERATION
Published 2016-12-01“…., inhibits proliferation and other endothelial cell functions related to angiogenesis. To confirm a leading role of arginine deiminase, as a factor responsible for the anti-proliferative effect, we have constructed an isogenic S. pyogenes M49-16 mutant unable to express arginine deiminase. …”
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7783
p53 enhances elesclomol-Cu-induced cuproptosis in hepatocellular carcinoma via FDXR-mediated FDX1 upregulation
Published 2025-06-01“…In mutant p53-R249S cells, CP-31398 functioned synergistically with elesclomol-Cu to suppress proliferation. …”
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7784
Vulvovaginal atrophy: modern approaches to diagnostics and management
Published 2024-01-01“…The pathogenesis of vulvovaginal atrophy is associated with hypoestrogeny which results in structural and functional abnormalities of the genital organs such as mucus thinning, loss of elasticity, changes in microbiota and increased pH. …”
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7785
CD8 T cell-mediated depletion of HBV surface-antigen-expressing, bilineal-differentiated liver carcinoma cells generates highly aggressive escape variants
Published 2023-12-01“…HBV developed immune-suppressive functions to escape from the host immune system, but their link to liver tumor development is not well understood. …”
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7786
Identification of QTLs for early maturity-related traits based on RIL population of two elite cotton cultivars
Published 2024-12-01“…One particular QTL cluster, which had the largest number of QTLs, ranged from 108.5 cM to 109 cM on Dt3, and contained 39 genes. Through functional analysis, we highlighted two early maturity-related candidates of GH_D03G1554 and GH_D03G1541, which were annotated as a BEL1-like homeodomain protein 8 and a homeobox-leucine zipper family protein, respectively. …”
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7787
Targeting the dual miRNA/BMP2 network: LncRNA H19-mediated temozolomide resistance unveils novel therapeutic strategies in glioblastoma
Published 2025-04-01“…Notably, lncRNA H19 functions as a molecular decoy for hsa-miR-138-5p and hsa-miR-22-3p, and these miRNAs can reverse the acquired TMZ resistance induced by lncRNA H19 in GBM cells. …”
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7788
Identification and validation of a lenvatinib resistance-related prognostic signature in HCC, in which PFKFB4 contributes to tumor progression and lenvatinib resistance
Published 2025-04-01“…Lenvatinib is the first-line therapy for hepatocellular carcinoma (HCC), but its effectiveness is limited by rapid development of resistance. …”
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7789
The Soviet Military Microbiologists’ Contribution to the Victory in the Great Patriotic War
Published 2025-07-01“…Scientific publications and papers that are related to epidemic prosperity state at the front line and rear areas the Great Patriotic War neglect the importance of military microbiologists. …”
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7790
Rapid method for identification of transgenic fish zygosity
Published 2007-07-01“…In this experiment, we applied a quantitative real-time PCR (qr-PCR) method to analyze zygosity in a stable line of transgenic zebrafish (Danio rerio) carrying masu salmon, Oncorhynchus masou D6-desaturase-like gene. …”
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7791
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7792
Kinin B<sub>1</sub> Receptor Agonist Enhances Blood-Brain Barrier Permeability in Healthy and Glioblastoma Environments
Published 2025-04-01“…The effect of DBK on enhancing paracellular molecule transport was evaluated using Evans blue dye (EB) quantification in a cell culture insert assay and in an in vivo model, where mice with and without brain tumors were treated with DBK. To assess the functional impact of the transient BBB opening induced by DBK, the chemotherapeutic drug doxorubicin (DOX) was administered. …”
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7793
Early and Late Responses of Cultured Human Mesenchymal Stem Cells (MSCs) to Cell-free DNA (cfDNA) in Patients With Acute Myocardial Infarction
Published 2025-03-01“…Potentially, ami-cfDNA can influence the functional activity and direction of stem cell differentiation. …”
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7794
Effects of smoking on the level of sp-a and sp-d surfactant proteins in the blood of patients without bronchopulmonary diseases
Published 2020-07-01“…Respiratory epithelium is the first line of defense against exogenous invasion, in particular, harmful inhaled particles, pathogens and allergens. …”
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7795
Reconfigurable and Highly-Miniaturized Low-Noise Amplifiers Based on Tunable Filtering Loads
Published 2025-01-01“…The proposed LNAF concepts are based on complex-terminated bandpass filter (BPF)-type output matching networks that facilitate quasi-elliptic transfer functions that can be tuned in terms of bandwidth (BW), center frequency (<inline-formula> <tex-math notation="LaTeX">$f_{cen}$ </tex-math></inline-formula>), and can be intrinsically switched-off. …”
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7796
Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression
Published 2025-08-01“…The CSF-1/CSF-1R signaling pathway is essential for the physiological functions of myeloid lineage cells, including osteoclasts and monocytes/macrophages. …”
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7797
Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic...
Published 2025-08-01“…Immune infiltration and drug sensitivity were evaluated by CIBERSORT, ESTIMATE, xCell, TIDE, and pRRophetic. Functional validation encompassed siRNA knockdown, qRT-PCR, Western blot analysis, and cellular assessment in CRC cell lines.ResultsWe discovered four categories of tumor cells exhibiting variations in cell cycle, stemness, and differentiation. …”
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7798
Heme Oxygenase-1 Modulates Macrophage Polarization Through Endothelial Exosomal miR-184-3p and Reduces Sepsis-Induce Lung Injury
Published 2025-04-01“…Heme oxygenase-1 (HO-1), an early stress-responsive enzyme with inherent protective functions, has been implicated in acute lung injury (ALI) mitigation. …”
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7799
Development of a machine learning-based predictive risk model combining fatty acid metabolism and ferroptosis for immunotherapy response and prognosis in prostate cancer
Published 2025-05-01“…In vitro experiments showed that overexpression of CD38 in the PC-3 cell line led to elevated lipid peroxidation (C11-BODIPY) and reactive oxygen species (ROS), suggesting increased cell ferroptosis. …”
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7800
Association between taurine transporter SLC6A6 and breast cancer development and prognosis: a Mendelian randomization analysis
Published 2025-07-01“…Molecular docking, functional analysis, and immune infiltration analysis were employed to explore the mechanism of SLC6A6. …”
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