SILVER NANOPARTICLES IN THE SOLUTION OF THE PROBLEM OF DRUG RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS by A. V. Zaharov, A. L. Khokhlov, A. E. Ergeshov

“…In the studied doses of isolated silver nanoparticles do not affect the basic biometrics, laboratory and functional parameters of the animals, and do not increase the toxicological parameters of isoniazid. …”
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Wpływ Przepon Pośrednich na Stateczność Pręta Cienkościennego by A. Chudzikiewicz

“…The buckling described by the functions ξ(x) and ϕ(x) (Fig. 3) is considered. In view of the symmetry the equations are established for one flange only. …”
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Necrotic and Inflammatory Changes on Acute Studies of Siam Leaf (Chromolaena Odorata) Alcoholic Extract on Lead Induced Toxicity of Cardio-Pulmonary Morphology of Adult Albino Wist... by Ilegbedion, I.G.1*, Beredugo, S.,2 Aturaka, O.S.3, Tabowei, W.T.4.

“…Long-term exposure of adults can result in decreased performance in some tests of cognitive performance that measure functions of the nervous Cardio-pulmonary system.  …”
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Transcriptomic analysis of non-leukemic cell subsets in azacytidine-responsive AML highlights pathways associated with adhesion, platelet aggregation, and angiogenesis in mice and... by Nancy D. Ebelt, Suvithanandhini Loganathan, Lara C. Avsharian, Edwin R. Manuel

“…Methods Whole blood and spleens from vehicle- or AZA-treated mice implanted with the syngeneic AML line C1498 were transcriptionally profiled using a comprehensive panel of immune-related gene probes. …”
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Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway by Jiawei Zhou, Anqi Cheng, Jianqiang Guo, Yafeng Liu, Xuan Li, Maoqian Chen, Dong Hu, Jing Wu

“…A stable PRDX2-knockdown triple-negative breast cancer cell line was established using lentiviral technology. …”
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Cross-reactivity of rPvs48/45, a recombinant Plasmodium vivax protein, with plasma from Plasmodium falciparum endemic areas of Africa. by Saidou Balam, Kazutoyo Miura, Imen Ayadi, Drissa Konaté, Nathan C Incandela, Valentina Agnolon, Merepen A Guindo, Seidina A S Diakité, Sope Olugbile, Issa Nebie, Sonia M Herrera, Carole Long, Andrey V Kajava, Mahamadou Diakité, Giampietro Corradin, Socrates Herrera, Myriam Arevalo Herrera

“…This, together with the functional activity of IgG, warrants further studies for the potential development of a P. vivax and P. falciparum cross-protective TB vaccine.…”
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Enhanced wombat optimization algorithm for multi-objective optimal power flow in renewable energy and electric vehicle integrated systems by Karthik Nagarajan, Arul Rajagopalan, Mohit Bajaj, Valliappan Raju, Vojtech Blazek

“…Further, the authors also used Weibull, lognormal and normal probability distribution functions (PDFs) for characterizing the uncertainties faced in solar PV, wind energy and PEV sources. …”
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ASSISTITO, SUPPORTATO O GENERATO DALL’IA: UNA TASSONOMIA ISPIRATA DALLA CAPTOLOGIA PER L’USO DELL’INTELLIGENZA ARTIFICIALE NELLA DIDATTICA by Martin Ruskov

“…Starting with the components of captology’s functional triad, we collocate representative examples that help illustrate the proposed taxonomy. …”
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MicroRNA-18b-5p Inhibits the Malignant Progression of Prostate Cancer Through Downregulating TRAF5 by Wang X, Yu X, Wang Y, Lian J, Li Z, Dong C, Song H, Zhang L, Zhang H, Wang Y

“…In-vitro experiments were conducted to investigate the biological functions of miR-18b-5p and TRAF5 in PCa cells. The underlying mechanism of miR-18b-5p was revealed by luciferase reporter assay, miRNA Pull down, RT-qPCR, and rescue assay.Results: Lower miR-18b-5p and higher TRAF5 expression were observed in PCa tissues and cell lines. miR-18b-5p overexpression or TRAF5 downregulation impaired proliferation, diminished migratory and invasive properties, as well as advanced apoptosis in PCa cells. miR-18b-5p could regulate TRAF5 expression by directly binding to its 3′-untranslated region. …”
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Comparison of dyspareunia using female sexual index score in 3-month, 6-month, and 12-month postpartum after vaginal delivery and cesarean section: meta-analysis by Eighty Mardiyan Kurniawati, Zettira Maulida Prasha, Hari Paraton

“…There is a change in mindset due to the change in women’s role, let alone the perception stating that cesarean delivery can decrease the risk of having pelvic floor dysfunction and maintain the sexual functions. Therefore, women think that cesarean delivery is a good choice for delivery, even it has no indications. …”
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Natural epigallocatechin-3-gallocarboxylate nanoformulation loaded doxorubicin to construct a novel and low cardiotoxicity chemotherapeutic drug for high-efficiency breast cancer t... by Ke Wang, Siqi Geng, Fang Wang, Baoru Fang, Huifeng Qian, Ying Li, Yiqing Zhou, Yanping Chen, Zhangsen Yu

“…Abstract Anthracycline doxorubicin (DOX) remains the first-line chemotherapeutic drug for the efficient treatment of breast cancer, but its severe cardiotoxicity limits its long-term application in clinical tumor chemotherapy. …”
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Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway by Chenrui Yang, Yanzhong Zhang, Yajuan Liu, Xiaoyong Wu, Fangyuan Sun

“…Methods This study integrated HCC datasets (GSE135631, GSE184733, GSE202853) from the gene expression omnibus (GEO) database to screen for differentially expressed genes (DEGs), perform functional enrichment analysis, weighted gene co-expression network analysis (WGCNA), construct protein–protein interaction (PPI) networks, and conduct survival analysis. …”
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MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer by Yishan Huang, Ting Yang, Chen Yang, Bo Tang, Bo Su, Xiaojun Yang

“…The identification of differentially expressed genes (DEGs) and subsequent analyses, including signaling pathway enrichment, functional classification, and protein-protein interaction (PPI) network construction, were conducted using three public datasets: GSE32676, GSE71989, and GSE16515. …”
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Role of Fcγ receptors in HER2-targeted breast cancer therapy by Hope S Rugo, Antonino Musolino, William J Gradishar, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

“…Trastuzumab has, nonetheless, revolutionized HER2+ breast cancer treatment, and several HER2-directed mAbs have been developed using Fc glyco-engineering or Fc protein-engineering to enhance FcγR-mediated functions. An example of an approved anti-HER2 Fc-engineered chimeric mAb is margetuximab, which targets the same epitope as trastuzumab, but features five amino acid substitutions in the IgG 1 Fc domain that were deliberately introduced to increase binding to activating FcγRIIIa and decrease binding to inhibitory FcγRIIb (CD32B). …”
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GPU Acceleration for FHEW/TFHE Bootstrapping by Yu Xiao, Feng-Hao Liu, Yu-Te Ku, Ming-Chien Ho, Chih-Fan Hsu, Ming-Ching Chang, Shih-Hao Hung, Wei-Chao Chen

“…In summary, our accelerator offers improved efficiency, scalability, and flexibility for extensions, e.g., functional bootstrapping (Liu et al., Asiacrypt 2022), compared to current state-of-the-art solutions. …”
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Exploring genetic diversity and genomic inbreeding across local beef cattle breeds by G. Gomez Proto, E. Mancin, A. Quaglia, F. Sbarra, R. Mantovani, C. Sartori

“…Gene Ontology enrichment analyses indicated their involvement in relevant biological functions. Overall, this study provides a comprehensive genomic characterisation of five Italian beef cattle breeds, emphasising their differentiation, demographic history, and signatures of selection. …”
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HEALTH-PRESERVING COMPETENCE AS A COMPONENT OF THE PROFESSIONAL COMPETENCE OF THE FUTURE PRIMARY SCHOOL TEACHER by Romanyshyna Lyudmyla, Kryshchuk Bogdan, Polishchuk Oleksandr

“…General competence is understood as the functional essence of a person’s general culture, while professional competence refers to the professional culture of a specialist, and the content of their professionalism. …”
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Pan-cancer analysis of GJB5 as a novel prognostic and immunological biomarker by Xiaojuan Yang, Xunjie Cao, Qing Zhu, Hong Wu

“…Abstract Gap junction protein B5 (GJB5, also known as Connexin 31.1) has recently been reported to be downregulated in several cancer types, where it functions primarily as a tumor suppressor in cancers such as melanoma and non-small cell lung cancer (NSCLC). …”
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CLN-619, a MICA/B monoclonal antibody that promotes innate immune cell-mediated antitumor activity by Naveen K Mehta, Kristan Meetze, Patrick A Baeuerle, Jennifer S Michaelson, Kerry A Whalen, Kavya Rakhra, Catherine C Henry, Safak Yalcin, Neil W Gibson

“…Treatment of cancer cell lines with CLN-619 induced antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. …”
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Enhancing CAR T‐cell therapy manufacturing efficiency through semi‐automated bioprocessing by Jason Isaacson, Prajakta Bhanap, Nicholas Putnam, Jasmine Padilla, Nujhat Fatima, Max Dotson, Danny Hayoun, Moloud Ahmadi, Gertrude Nonterah, Yongchang Ji

“…Results The results demonstrated the successful generation of functional CAR T cells using a semi‐automated instrument workflow. …”
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