Exploring the Role of N-WASP in Breast Cancer Metastasis through Mass Spectrometry and Potential Signalling Pathway Analysis by Rhiannon Yannan Yu, Wenguo Jiang, Tracey Martin

“…In cancer biology, the role of N-WASP in cell motility and metastasis is of particular interest, yet its specific functions in breast cancer remain to be fully understood. …”
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Elucidating the role of AC026412.3 in hepatocellular carcinoma: a prognostic disulfidptosis-related LncRNAs model perspective by Qinghua Ji, Chuanbing Shi, Xuefeng Gu, Ling Yang, Yintao Sun

“…Concordance indices (C-index: 0.681) and principal component analysis further validated stratification efficacy. Functional annotation linked the signature to extracellular matrix dysregulation, epithelial-mesenchymal transition, and immunosuppressive microenvironments. …”
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Exosome-delivered METTL14 drives hypoxia-induced proliferation, metastasis, and glycolysis of breast cancer cells through regulating TRIM16-mediated FGF7 ubiquitination by Bo Huang, Yichao Zhang, Zhanjun Chen, Yuanyuan Yuan, Jianshan Lin

“…Functionally, FGF7 knockdown suppressed hypoxia-induced TNBC cell proliferation, metastasis, and glycolysis. …”
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Technique for reducing the surgical porosity of small-diameter vascular grafts by E. A. Nemets, A. I. Khairullina, V. Yu. Belov, V. A. Surguchenko, V. N. Vasilets, V. I. Sevastianov, E. A. Volkova, Yu. B. Basok

“…The surface structure and mechanical properties of the samples were investigated. Functional properties of the bioactive VGs were evaluated in relation to their interaction with cell cultures in vitro.Results. …”
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Genetic determinism of cortisol levels in pig by Elena Terenina, Nathalie Iannuccelli, Yvon Billon, Katia Fève, Laure Gress, Darya Bazovkina, Pierre Mormede, Catherine Larzul

“…The difference between the two divergent lines was around five genetic standard deviations after three selection steps. …”
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Municipal healthcare providers’ perceptions of reasons for frequent and unplanned hospital admissions among home-dwelling older adults: a Norwegian focus group study by Jill-Marit Moholt, Cathrine Arntzen, Audhild Høyem, Bodil H. Blix

“…At the individual level, healthcare providers highlighted patient characteristics such as the severity of illness, reduced functional ability, living situation, and unmet psychosocial needs. …”
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Abstract 219: Determining the Proportion of Patients with Poor Premorbid mRS presenting with Large Volume Stroke by Madheea Siddiqi

“…Introduction Several lines of evidence demonstrate the effectiveness of endovascular treatment (EVT) for large volume stroke (LVS) as defined by Alberta Stroke Program Early CT Score (ASPECTS) of <6 in decreasing severe disability and death. …”
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Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies by Anna Wawruszak, Jarogniew Luszczki, Damian Bartuzi, Joanna Kalafut, Estera Okon, Arkadiusz Czerwonka, Andrzej Stepulak

“…Accumulative evidence suggests that each sirtuin possesses individual character, implicating its role in the regulation of multifaceted biological functions leading to BC initiation, progression and metastasis. …”
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Method of the Cyclotorsion Error Compensation for Myopic Astigmatism during SMILE Surgery by G. A. Gamidov, I. A. Mushkova, S. V. Kostenev, A. A. Gamidov

“…Purpose: to develop an effective and safe method of cyclotorsion compensation, to improve the clinical and functional results of the of myopic astigmatism correction with SMILE surgery.Patients and methods: Two equivalent groups of 30 people (30 eyes) were formed with cyclotorsion from ±5 degrees («Standard» and «Verion»). …”
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AGC of a Multi‐Area Hydrothermal Interconnected Diverse Deregulated Power System Using a Proposed Novel SBOA‐Multi‐Level Fuzzy Logic‐Tilt Controller Incorporated With IPFC by Getaneh Mesfin Meseret, Nishant Kumar, Tarkesh Kumar Mahato, Rajesh Kumhar, Poonam Lakra, M. D. Mofeed Alam

“…A significant drop in frequency can negatively affect electric clock synchronization, magnetizing currents in transformers and induction motors, the consistent speed of AC motors, the ongoing operation of processes, and the coordinated functioning of various components within the power system. …”
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Antioxidant, bioactive, and nutritional potential of soybeans with brown and yellow seed coats by Victor Delino Barasuol Scarton, Ivan Ricardo Carvalho, Christiane de Fátima Colet, Jaqueline Piesanti Sangiovo, Willyan Júnior Adorian Bandeira, Murilo Vieira Loro, Ellen Cristina Perin, Solange Teresinha Carpes, Patricia Brugnerotto

“…Given the growing interest in biofortification to enhance the nutritional value of crops, this study aimed to assess the agronomic performance, nutritional, functional and physicochemical composition of soybean lines with both brown and yellow seed coats, with a particular focus on their biofortification potential. …”
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IncRNA IPAN antagonizes RIG-I/TRIM25-mediated degradation of influenza A virus PB1 to promote viral replication by Tingting Sun, Shumin Chen, Rui Zhou, Saisai Guo, Yilu Ye, Jingyi Qiu, Xiaoyu Li, Shan Cen, Jing Wang

“…The productive infection of influenza A virus (IAV) requires the functional involvement of host long noncoding ribonucleic acids (lncRNAs). …”
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Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin by Ziwei Yang, Ziwei Yang, Tixin Han, Ruibin Yang, Ruibin Yang, Yinuo Zhang, Yinuo Zhang, Yifei Qin, Yifei Qin, Yifei Qin, Jialu Hou, Jialu Hou, Fei Huo, Fei Huo, Zhuan Feng, Zhuan Feng, Yaxin Ding, Yaxin Ding, Jiali Yang, Jiali Yang, Gang Zhou, Gang Zhou, Shijie Wang, Shijie Wang, Xiaohang Xie, Xiaohang Xie, Peng Lin, Peng Lin, Zhi-Nan Chen, Zhi-Nan Chen, Jiao Wu, Jiao Wu

“…Imidazole ketone erastin (IKE), an inhibitor of the system Xc– functional subunit solute carrier family 7 member 11 (SLC7A11), is an effective and metabolically stable inducer of ferroptosis with potential in vivo applications. …”
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An Adiabatic-Expansion-Induced Perturbation Study on Gas–Aerosol Partitioning in Ambient Air—Formation of NH₄NO₃ and Microdroplet Nitrogen Fixation (2) by Yating Gao, Qinchu Fan, Yujiao Zhu, Hengqing Shen, Qi Yuan, Yang Gao, Huiwang Gao, Xiaohong Yao

“…However, the current observational data do not allow us to derive a functional relationship between the redox reaction rate and these parameters, nor to fully detail the underlying chemistry. …”
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TMEM115: a promising marker for glioma immunotherapy and prognosis by Hang Yin, Hang Yin, Feng Wang, Feng Wang, Haiyan Xu, Haiyan Xu, Manyu Xu, Manyu Xu, Pengpeng Lu, Pengpeng Lu, Xiaojing Zhang, Lei Yang, Bing Lu, Pingping Sun, Jianfei Huang, Jianfei Huang

“…However, the role of TMEM115 in glioma progression is still unclear and, therefore, needs further exploration.MethodsRNA-seq data from The Cancer Genome Atlas and Chinese Glioma Genome Atlas databases of glioma patients and multiplex Immunohistochemistry by glioma tissue microarrays were analyzed to determine the expression and localization of TMEM115. Functional assessment of TMEM115 involved cell proliferation, migration, and invasion assays. …”
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Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti by Alexander Bergman, Anna B. Crist, Hélène Lopez-Maestre, Hervé Blanc, Mauro Castelló-Sanjuán, Lionel Frangeul, Hugo Varet, Josquin Daron, Sarah H. Merkling, Maria-Carla Saleh, Louis Lambrechts

“…Results We investigated the expression of TEs and small RNAs in both somatic and gonadal tissues of a Dicer2 mutant line of Ae. aegypti and its wild-type counterpart. …”
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Ubiquitin-specific peptidases in lymphoma: a path to novel therapeutics by Maryam Samareh Salavatipour, Shirin Tavakoli, Aram Halimi, Aram Halimi, Shima Tavoosi, Amir-Hossein Baghsheikhi, Abdolkarim Talebi-Taheri, Mehdi Niloufari, Zahra Salehi, Javad Verdi, Soheila Rahgozar, Alireza Mosavi-Jarrahi, Mohammad Ahmadvand

“…Understanding the intricate functions of USPs in lymphoma offers new insights into potential therapeutic strategies, emphasizing the significance of these enzymes in the context of cancer biology.…”
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Assessing inter-basin groundwater input to the Verlorenvlei estuarine lake using stable isotopes and hydrochemistry by A. Welham, J. van Rooyen, A. Watson, J. Miller, R. Chow

“…., agricultural expansion and groundwater abstraction) have threatened Verlorenvlei’s ecological functions. Seasonal and spatial changes between the water sources (i.e., direct rainfall, surface water, and groundwater) supporting Verlorenvlei were determined using δ18O and δ2H isotopes and hydrochemical analyses. …”
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Circ_0124346 facilitates cell proliferation of pancreatic adenocarcinoma cells by regulating lipid metabolism via miR-223-3p/ACSL3 axis by Meng-lu Shu, Wan-ting Yang, Hui-min Li, Cui-juan Qian, Xiao-sheng Teng, Jun Yao

“…Additionally, we found that circ_0124346 functioned as a sponge for miR-223-3p, preventing miR-223-3p’s binding to the 3'-UTR of ACSL3 mRNA, which subsequently led to an elevation in ACSL3 expression and promoted lipid synthesis. …”
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Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells by Jetzabel Vidal-Vidal, David Brown-Brown, Nelson Quilaqueo-Millaqueo, Gaspar Peña-Münzenmayer, Carlos Spichiger, Claudia Quezada-Monrás, Flavio Salazar-Onfray, Julio C. Tapia, Ignacio Niechi

“…Treatment also decreased the expression of EMT and stemness markers CD44 and Vimentin. Functionally, rNEP reduced cell migration, invasion, and colony formation, while SM19712 affected migration and colony formation. …”
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