Functional properties of barium titanate ceramics alloyed with nickel ferrite by Vladzimir M. Laletin, Natallia N. Poddubnaya, Iliya S. Nabzdorov, Yurij V. Radyush, Li Jin

“…X-ray phase analysis showed that in alloyed barium titanate the tetragonal splitting of lines is expressed more strongly, and the calculated lattice parameters a and c differ significantly from the parameters of pure barium titanate. …”
Get full text

Pyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream forms. by Juma A M Ali, Daniel N A Tagoe, Jane C Munday, Anne Donachie, Liam J Morrison, Harry P de Koning

“…Pyrimidine auxotrophs were able to infect mice although the infection developed much more slowly than infection with the parental, prototrophic trypanosome line.<h4>Conclusions/significance</h4>Pyrimidine salvage was not an essential function for bloodstream T. b. brucei. …”
Get full text

Cortical and Striatal Functional Connectivity in Juvenile-Onset Huntington’s Disease by Amy Barry, Peg C. Nopoulos

“…Conclusions: These findings support the hypothesis of antagonistic pleiotropy in JoHD, where early neural advantages—such as relatively preserved or possibly enhanced cortical function—may contribute to later striatal vulnerability and degeneration. …”
Get full text

Identification of functional non-coding variants associated with orofacial cleft by Priyanka Kumari, Ryan Z. Friedman, Sarah W. Curtis, Lira Pi, Kitt Paraiso, Axel Visel, Lindsey Rhea, Martine Dunnwald, Anjali P. Patni, Daniel Mar, Karol Bomsztyk, Julie Mathieu, Hannele Ruohola-Baker, Elizabeth J. Leslie-Clarkson, Michael A. White, Barak A. Cohen, Robert A. Cornell

“…To identify candidates for functional SNPs at eight such loci we conduct a massively parallel reporter assay in a fetal oral epithelial cell line, revealing SNPs with allele-specific effects on enhancer activity. …”
Get full text

Utilization of second medical opinions as a function of the payment method by Liora Shmueli, Tuvia Horev

Get full text

Reconstruction of Tokamak Plasma Emissivity Distribution by Approximation with Basis Functions by Tomasz Czarski, Maryna Chernyshova, Katarzyna Mikszuta-Michalik, Karol Malinowski

“…Within this framework, the reconstruction method employs an approximation model utilizing three sets of basis functions: (i) polynomial splines, as well as Gaussian functions with (ii) sigma parameters and (iii) position parameters. …”
Get full text

The Pragmatic Functions of the Idiomatic Expression Yalla in Jordanian Spoken Arabic by Джихад Хамдан, Діна Хаммоурі

“…The study reveals that Yalla conveys 23 pragmatic functions: showing approval / acceptance, signaling the start of an action, spreading enthusiasm, suggesting, commanding/ ordering someone, expediting/ urging, expressing surrender or submission, announcing the onset of a new stage, requesting approval, rest assuring, prompting someone to act in line with an established routine, advising coupled with warning, asking for patience/calming someone down, encouraging/ cheering, drawing attention, reminding, wishing, stimulating, underestimating the importance of a complaint, ridiculing/ mocking, expressing comfort, showing emphasis in addition to showing anger and boredom. …”
Get full text

Functional role of kallikrein 6 in regulating immune cell survival. by Isobel A Scarisbrick, Benjamin Epstein, Beth A Cloud, Hyesook Yoon, Jianmin Wu, Danielle N Renner, Sachiko I Blaber, Michael Blaber, Alexander G Vandell, Alexandra L Bryson

“…Notably, KLK6 is also elevated in the serum of multiple sclerosis (MS) patients however its potential roles in immune function are unknown. Herein we specifically examine whether KLK6 alters immune cell survival and the possible mechanism by which this may occur.…”
Get full text

Comprehensive functional annotation of 77 prostate cancer risk loci. by Dennis J Hazelett, Suhn Kyong Rhie, Malaina Gaddis, Chunli Yan, Daniel L Lakeland, Simon G Coetzee, Ellipse/GAME-ON consortium, Practical consortium, Brian E Henderson, Houtan Noushmehr, Wendy Cozen, Zsofia Kote-Jarai, Rosalind A Eeles, Douglas F Easton, Christopher A Haiman, Wange Lu, Peggy J Farnham, Gerhard A Coetzee

“…We define as risk enhancers those regions with enhancer chromatin biofeatures in prostate-derived cell lines with prostate-cancer correlated SNPs. To aid the identification of these enhancers, we performed genomewide ChIP-seq for H3K27-acetylation, a mark of actively engaged enhancers, as well as the transcription factor TCF7L2. …”
Get full text

TRIM22 functions as a scaffold protein for autophagy initiation by Hyungsun Park, Hansol Heo, Yeongseo Song, Myung Shin Lee, Yebin Cho, Jae-Seon Lee, Jaerak Chang, Seongju Lee

“…The Alzheimer's disease-associated TRIM22 variant R321K maintained autophagy initiation function in both cell lines and primary neurons. These findings demonstrate that TRIM22 acts as a scaffold protein to promote autophagy initiation, in addition to its previously described role in autophagosome-lysosome fusion. …”
Get full text

The functional role of CST1 and CCL26 in asthma development by Angela Hoyer, Sandip Chakraborty, Ingrid Lilienthal, Jon R. Konradsen, Shintaro Katayama, Cilla Söderhäll

“…The aim of our study was to investigate the functional mechanism of CST1 and CCL26 in the alveolar basal epithelial cell line A549. …”
Get full text

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide by Radmila Milenkovska, Nikola Geskovski, Dushko Shalabalija, Ljubica Mihailova, Petre Makreski, Dushko Lukarski, Igor Stojkovski, Maja Simonoska Crcarevska, Kristina Mladenovska

“…Cytotoxicity and effects on cell membrane integrity of the blank and TMZ-loaded dual-functionalized carbon nanostructures (CNs) were evaluated in vitro on a GBM cell line (U87MG), as well as their radiosensitizing properties after exposure of the pre-treated GBM cells to gamma radiation with a standard clinical dose for patients with GBM. …”
Get full text

PFAS exposure during pregnancy: Implications for placental health and functioning by Sadia Khan, Marion Ouidir, Nicolas Lemaitre, Nicolas Jovanovic, Sam Bayat, Sarah Lyon-Caen, Pascale Hoffmann, Morgane Desseux, Cathrine Thomsen, A. Couturier-Tarrade, Line Småstuen Haug, Séverine Valmary-Degano, Valérie Siroux, Rémy Slama, Nadia Alfaidy, Claire Philippat

Get full text

Optimal selection of wastewater treatment and location for subway stations using mathematical techniques: Five stations at the eastern end of Tehran subway line 2 by Sepideh Ghaderi, amirhossien javid, Hamidreza Ghaffarzadeh, Farhad Hosseinzadeh Lotf

“…However, making these two decisions at the same time is a function of several parameters. MCDM technique is one of the best options when controversial criteria need to be taken into account. …”
Get full text

The molecular mechanism and utilization of ZmMs7-mediated dominant nuclear sterility in Oryza sativa L by Yusheng Xu, Yusheng Xu, Dingyang Yuan, Meijuan Duan

“…The system has successfully developed a practical dominant male-sterile rice line characterized by complete pollen sterility, stable fertility, and straightforward visual seed selection, with no adverse effects on plant growth. …”
Get full text

Non-uniform Rectilinear Grid in the Waveguide Modeling of the Vocal Tract by Tahir Mushtaq QURESHI, Khalid Saifullah SYED, Asim ZAFAR

“…In this work, there are two types of delay lines: one is called a smaller-delay line and other is called a larger-delay line. …”
Get full text

Research on the Combined Load-Bearing Mechanism of Deeply Buried Pressure Pipelines Under High Internal Water Pressure by LIU Yijie, ZHANG Xuhui, HUANG Bensheng, YANG Fengjie, YUAN Mingdao, XU Yunqian

“…In this stage, the corresponding internal water pressure and form of the steel lining’s potential function can be determined based on the prescribed deformation value at the outer boundary of the steel lining. 2) In the joint bearing stage, when the internal water pressure exceeded a critical threshold, the steel lining and concrete layer achieved full contact and continued to expand together. …”
Get full text

Urban Renewal Strategy Guided by Rail Transit Development Based on the “Node–Place–Revenue” Model: Case Study of Shenyang Metro Line 1 by Xu Lu, Mengqin Zhu, Zeting Li, Qingyu Li, Shan Huang

“…Taking Shenyang Metro Line 1 as an example, the study first used the model to measure the node value, place value, and revenue value of each sample TOD station area. …”
Get full text

Investigating Low-Frequency Electromagnetic Fluctuations on PCB Surfaces: A Near-Field Analysis of CBCPW Transmission Lines up to 15.2 MHz by Mariusz Zubert, Mariusz Jankowski, Zbigniew Kulesza

“…The paper employs statistical methods to model low-frequency electromagnetic field fluctuations over printed circuit boards (PCBs) using near-field measurements within the frequency domain along the Coplanar Broadband Capacitance Wave (CBCPW) transmission line. The study characterizes electromagnetic noise profiles up to 15.2 MHz, assesses the impact of transmission lines (TL) on PCB environments, and explores the effects of signal interference. …”
Get full text

Generation of a homozygous ABCA7 knockout cell line (AHMUCNi002-A) in human iPSCs using CRISPR/Cas9 by Juanjuan Li, Letian Yin, Chengwei Wang, Yin Xu

“…ABCA7, located on chromosome 19, encodes an ATP-binding cassette transporter. Loss-of-function variants of ABCA7 are associated with an increased risk of Alzheimer’s disease. …”
Get full text