Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway by Manzila Kuerbanjiang, Lei Gu, Chunjie Xu, Wen Ting Xu, Siyuan Wen, Hanbing Xue, Qing Xu

“…Further study found that MPC2 knockdown in CRC cell lines activated the mTOR signaling pathway, and the addition of rapamycin reversed the promoting effect of MPC2 knockdown on CRC proliferation and glycolysis. …”
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ANGPTL3 overcomes sorafenib resistance via suppression of SNAI1 and CPT1A in liver cancer by Yang-Hsiang Lin, Cheng-Yi Chen, Hsiang-Cheng Chi, Meng-Han Wu, Ming-Wei Lai, Chau-Ting Yeh

“…Functionally, ectopic expression of ANGPTL3 re-sensitized sorafenib-resistant cells, enhancing the sorafenib-induced reduction in cell viability and migration by suppressing zinc finger protein SNAI1 (SNAI1) expression and the protein stability of carnitine O-palmitoyltransferase 1, liver isoform (CPT1A). …”
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Three-dimensional diffractive acoustic tomography by Luca Menozzi, Tri Vu, Aidan J. Canning, Harshal Rawtani, Carlos Taboada, Marie Elise Abi Antoun, Chenshuo Ma, Jesse Delia, Van Tu Nguyen, Soon-Woo Cho, Jianing Chen, Theresa Charity, Yirui Xu, Phuong Tran, Jun Xia, Gregory M. Palmer, Tuan Vo-Dinh, Liping Feng, Junjie Yao

“…Abstract Acoustically probing biological tissues with light or sound, photoacoustic and ultrasound imaging can provide anatomical, functional, and/or molecular information at depths far beyond the optical diffusion limit. …”
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Characterization of Bunch Compactness in a Diverse Collection of <i>Vitis vinifera</i> L. Genotypes Enriched in Table Grape Cultivars Reveals New Candidate Genes Associated with Be... by Marco Meneses, Claudia Muñoz-Espinoza, Sofía Reyes-Impellizzeri, Erika Salazar, Claudio Meneses, Katja Herzog, Patricio Hinrichsen

“…Enrichment analysis of significant and frequent SNPs found simultaneously in several traits and seasons revealed the over-representation of discrete functions such as alpha-linolenic acid metabolism and glycan degradation. …”
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AN ORPHAN PHENOTYPE OF CARDIOGENITAL LAMINOPATHY — MALOUF SYNDROME by T. G. Vaykhanskaya, L. N. Sivitskaya, N. G. Danilenko, T. V. Kurushko, O. G. Nizhnikova, O. G. Davydenko

“…Recent decades significantly increased the spectrum of monogenic diseases associated with mutations in the gene of lamin A/C (LMNA), that codes the proteins group performing important functions in the nucleus. This pathology presents with diverse systemic tissue involvement. …”
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The Emerging Role of Computed Tomography Coronary Angiography in the Left Main Stem Percutaneous Coronary Intervention by Asad Shabbir, Abdelrahman Attia, Nikkole Marie Weber, Mustafa Alhassan, Monika Radike, Conor M Lane, Apurva Bhavana Challa, Malgorzata Wamil

“…These innovations allow for comprehensive anatomical and functional assessments, enabling precise plaque morphology, lesion complexity, and bifurcation anatomy evaluations alongside PCI simulations. …”
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Integrative QTL Mapping and Transcriptomic Profiling to Identify Growth-Associated QTL and Candidate Genes in Hong Kong Catfish (<i>Clarias fuscus</i>) by Yian Zhu, Dayan Zhou, Yijun Shen, Chuanhao Pan, Yu Chen, Yulei Zhang, Binlan Yang, Guangli Li, Huapu Chen, Changxu Tian

“…A total of 162 functional genes were annotated within these QTL intervals. …”
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Integrin-Linked Kinase (ILK) Regulates Urinary Stem Cells Differentiation into Smooth Muscle via NF-κB Signal Pathway by Liang-liang Huang, Jun-hong Deng, Jing-xuan Xie, Zi-bin Lin, Hui Jiang, Bin Ouyang, Jian-ming Liu, Yan-ni Wei, Zhou-da Cai

“…An immortalized USCs cell line with the molecular markers and biological functions was prepared. …”
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PMAIP1-mediated glucose metabolism and its impact on the tumor microenvironment in breast cancer: Integration of multi-omics analysis and experimental validation by Yidong Zhang, Hang Xu, Xuedan Han, Qiyi Yu, Lufeng Zheng, Hua Xiao

“…The results were validated by in vitro experiments with MCF-7 and MCF-10A cell lines, including expression validation, functional experiments, and bulk sequencing. …”
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Titano-magnetite nanoparticles for supercapacitors and magnetic hyperthermia performance by Amol B. Pandhare, Swapnajit V. Mulik, Prashant N. Nikam, Satish S. Phalake, Vishwajeet. M. Khot, Manikandan Ayyar, Senthilkumar Ramasamy, Sagar D. Delekar, Rajendra P. Patil, P. Prabhu, Abdullah M. S. Alhuthali, Magda H. Abdellattif, M. Khalid Hossain

“…Abstract This study investigates the dual functionality of titano-magnetite (Ti0.5Fe2.5O4) nanoparticles (NPs) synthesized via a green approach for both magnetic hyperthermia and energy storage applications. …”
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Human lung organoids reveal conserved CYP1A1 and metallothionein activation in response to particulate matter exposure by Seri Choi, Seung-Yeon Kim, Ji Won Baek, Won Keun Oh, Kee K. Kim, Eun-Mi Kim

“…Particulate matter (PM) poses significant adverse impacts on respiratory health, yet most studies investigating PM effects have relied on cancer-derived cell lines or animal models with limited physiological relevance to human lung tissue. …”
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Effects of Acidic Polysaccharide-Enriched Extracts from <i>Holothuria tubulosa</i> on Two- and Three-Dimensional Invasive Breast Cancer Cell Models by Cristina Ciampelli, Sylvia Mangani, Gabriele Nieddu, Marilena Formato, Paraskevi Ioannou, Spyros Kremmydas, Nikos Karamanos, Antonio Junior Lepedda

“…In this study, we investigated the effects of two acidic polysaccharide-enriched (APs) fractions (Ht1 and Ht2) from the sea cucumber species <i>Holothuria tubulosa</i> on the highly invasive cell line MDA-MB-231. Functional assays were performed to assess cell viability, migratory potential, adhesion on collagen I, and cell morphology, alongside gene expression analysis. …”
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Controlling CRISPR-Cas9 genome editing in human cells using a molecular glue degrader by Namita Khajanchi, Vrusha Patel, Ronak Dua, Meha Kabra, Bikash R. Pattnaik, Krishanu Saha

“…Cells edited with the Cas9-d system were healthy and functional, exhibiting minimal toxicity from using the strategy. …”
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Adsorptive removal of Cr(VI) from wastewater using termite mound blended with chicken eggshell as an adsorbent: Equilibrium and kinetic approaches by Mebratu Ergete Mengistu, Yasin Ahmed Waday, Wondwosen Sime Geleta, Yigezu Mekonnen Bayisa, Dereje Tadesse Mekonnen

“…In the present study, environmental friendly adsorbent was produced from termite mound blended with chicken eggshell through calcination process to remove Cr(VI) from contaminated water. In line with this, the synthesized termite mounds blended with chicken eggshells (TMESP) adsorbent was assessed depending on their structural patterns, functional group, optical properties, and loss of mass using XRD, FTIR, UV–Vis spectra, and TGA, respectively. …”
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FAM72A promotes UNG2 degradation and mutagenesis in human cancer cells by Yuqing Feng, Philip Barbulescu, Chetan K. Chana, Melika Shirdarreh, Hong Yang, Lizhen Wu, Sami Mamand, Mohammad Kashem, Amin Zia, Ming Han, Julissa Tsao, Trevor Pugh, David Cescon, David G. Schatz, Frank Sicheri, Alberto Martin, Rossanna C. Pezo

“…Bioinformatic studies suggested that the human FAM72 genes are overexpressed in a broad range of cancers. However, the functional roles of FAM72A-D in human biology and cancer are unknown. …”
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Seasonal anti-androgen activity in the brackish Baltic waters in relation to the gene expression profiles of the blue mussel Mytilus trossulus by Paulina Goździk, Katarzyna Smolarz, Magda Caban, Anna Hallmann

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Features of Lipid Spectrum and Insulin Resistance Parameters in Patients with Type 2 Diabetes Mellitus and Cardiac Autonomic Neuropathy and Appropriateness of Simvastatin and Omega... by Azhmi S., Serhiyenko V.

“…Statins are widely accepted as the first-line therapy of the atherogenic DLP, the effectiveness of its prescription was proved in several studies. …”
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Dual drug-loaded tumor-targeted polymeric nanoparticles for enhancing therapeutic response in pancreatic ductal adenocarcinoma by Naga Malleswara Rao Nakka, Hari Krishnareddy Rachamala, Ramcharan Singh Angom, Nagamalleswara Rao Indla, Shamit Kumar Dutta, Enfeng Wang, Santanu Bhattacharya, Annadanam V. Sesha Sainath, Hani Babiker, Krishnendu Pal, Debabrata Mukhopadhyay

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The Role of Red Yeast Rice Based Preparations for Non-Pharmacological Correction of Dyslipidemia in Patients with Low and Moderate Cardiovascular Risk (Expert Opinion) by M. V. Ezhov, A. Catapano, C. Escobar, V. V. Kukharchuk, M. I. Voevoda, O. M. Drapkina, S. A. Shalnova, A. V. Starodubova, V. S. Gurevich, I. I. Shaposhnik, O. O. Bolshakova, O. S. Oynotkinova, A. S. Alieva

“…Evaluation of dietary supplements and functional foods should necessarily include not only evidence of beneficial effects with respect to effects on the lipid profile and atherosclerosis, but also proven good tolerability. …”
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Optimization by Hydrogen Plasma Treatment of a-CH and Hydrogen/Nitrogen-Assisted a-CH Layers for SAW Sensors by Veronica Satulu, Mihai Paunica, Simona Brajnicov, Sorin Vizireanu, Gheorghe Dinescu, Bogdana Mitu, Cristian Viespe

“…The hydrogen plasma treatment resulted in significant modifications in the topographical features, including roughness increase and notable variations in the surface aspect ratios, as confirmed through AFM data analysis, which involved advanced pixel height analysis and line profile processing. X-ray photoelectron spectroscopy (XPS) studies indicated the formation of new functional groups, increased defect density, and a significant reduction in electron transitions following hydrogen plasma treatment. …”
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