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7041
Development and Investigation into the Psychometric Properties of the Troy Sleep Scale
Published 2025-03-01“…The item analyses conducted in line with the IRT proved that the scale items provided a high level of information and functioned together with the answer set. …”
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7042
Delivery of an ERK inhibitor using bioactive lipid nanoparticles reduces angiogenesis and prevents oral squamous cell carcinoma development
Published 2025-07-01“…In this study, we utilized bioactive phospholipids (dipalmitoyl phosphatidic acid, DPPA) with antiangiogenic functions to encapsulate a small-molecule ERK inhibitor (called NP-AE) and constructed an intrinsically biotherapeutically active nanomedicine delivery platform with dual therapeutic efficacy. …”
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7043
Antioxidant and Biological Activity of Mexican Madroño Fruit (<i>Arbutus arizonica</i>)
Published 2024-09-01“…The extract also showed α-glucosidase inhibition (IC<sub>50</sub> = 3.1 ± 0.17 mg/mL), but no inhibition against α-amylase and lipase (>5 mg/mL), while showing antiproliferative activity against HeLa, HT-29, and MCF-7 cancer cell lines. These results point towards an interesting potential for the fruit of the <i>A. arizonica</i> as chemopreventive and hold potential for elaborating functional foods.…”
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7044
BioGoldNCDB: A Database of Gold Nanoclusters and Related Nanoparticles with Biomedical Activity
Published 2025-08-01“…AuNCs, with a core size smaller than 2 nm, represent a unique class of functional nanomaterials. Their distinctive properties enable innovative applications across various interdisciplinary fields. …”
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7045
Theta-frequency subthalamic nucleus stimulation increases decision threshold
Published 2025-07-01“…Introduction: Executive functions are often impaired in patients with Parkinson's disease (PD), and these deficits can be predicted by decreased frontal cortical 4–8 Hz theta activity that is associated with cognitive control. …”
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7046
TARGETING PRC2 ENHANCES THE ANTITUMOR CYTOTOXIC CAPACITY OF ANTI-CD19 CAR-T CELLS AGAINST HEMATOLOGICAL MALIGNANCIES
Published 2024-10-01“…Collectively, our results demonstrated that targeting PRC2 may be a promising approach to enhance a functional effector program in CAR-T cells against hematological malignancies.…”
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7047
Artificial Intelligence and Artistic Imagination: Revisiting the Cultural Economy of Industrial Revolutions
Published 2024-05-01“…The economics of culture, notwithstanding its deeply rooted epistemological fragilities – “pricing the pricelessness” of masterpieces or fitting artistry into “production functions” –, is in greater distress when asked to predict how tech sense will affect human sensibility. …”
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7048
Immunogenetic diversity of MHC class II B-Lβ genes in Brazilian Caipiras (free-range) chickens laying blue eggs
Published 2025-08-01“…Conservation and utilization of this genetic resource can contribute to the development of healthier and more disease-resistant commercial chicken lines.…”
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7049
Velocity Structure Correlations between the Nebular, Molecular, and Atmospheric Gases in the Cores of Four Cool Core Clusters
Published 2025-01-01“…We investigate the velocity structure of nebular gas in the central galaxies of four clusters: A1835, PKS 0745−191, A262, and RXJ0820.9+0752, using data from the Keck Cosmic Web Imager. Velocity structure functions (VSFs) of the [O ii ] emission line are compared to VSFs of molecular clouds observed with the Atacama Large Millimeter/submillimeter Array. …”
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7050
A systematic review on botanical background, phytochemical and pharmacological properties of Nymphaea nouchali
Published 2024-12-01“…These chemicals are associated with notable biological functions. Alkaloids and tannins had antibacterial activities, but phenolic compounds and flavonoids showed potent antioxidant capabilities. …”
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7051
Orexin A Affects INS-1 Rat Insulinoma Cell Proliferation via Orexin Receptor 1 and the AKT Signaling Pathway
Published 2013-01-01“…This finding provides functional evidence of the biological actions of OXA in rat insulinoma cells.…”
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7052
Enabling beam-scanning antenna technologies for terahertz wireless systems: A review
Published 2025-03-01“…While producing a scannable highly-directive antenna beam proves to be indispensable in the period of microwaves, the significance of such functionality is more critical in the THz era, considering that THz waves have more intractable challenges such as the severity of free-space propagation losses, the susceptibility to atmospheric environments, and the unavailability of efficient signal sources. …”
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7053
Overexpression in Plasmodium falciparum of an intrinsically disordered protein segment of PfUT impairs the parasite’s proteostasis and reduces its growth rate
Published 2025-05-01“…While this poses challenges for the parasite, the propensity for protein aggregation may also serve functional roles, such as stress adaptation, and could therefore be exploited by targeting it as a potential vulnerable spot in the pathogen. …”
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7054
The prevalence of posture pathology in school-aged children (results of a population-based study with the use of the computerized photo-geometric program “Posture”)
Published 2020-06-01“…Deviation of the spinal column from the midline in the frontal, sagittal plane (functional and organic disorders of posture) was observed in 75.3 % of children. …”
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7055
Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis
Published 2024-12-01“…These results highlight the inflammatory roles of elevated PRL at the maternal-fetal interface, underscoring the need for further mechanistic studies to elucidate its functions in pregnancy.…”
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7056
Long non-coding RNA NEAT1 promotes multiple myeloma malignant transformation via targeting miR-485-5p/ABCB8
Published 2024-12-01“…We demonstrated that NEAT1 was up-regulated in MM tissues and cell line. NEAT1 silencing significantly inhibited cell proliferation and promoted cell apoptosis in vitro. …”
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7057
An intraepithelial ILC1-like natural killer cell subset produces IL-13
Published 2025-03-01“…Here, we identify a subpopulation of ex vivo differentiated ieILC1-like NK cells that produce IL-13 upon stimulation. Functional characterization revealed that these cells co-expressed IFNγ and IL-13 while maintaining an ILC1 transcriptional signature. …”
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7058
5G Fronthaul in Modular P4: eCPRI Protocol Processing and Precise BMv2 Timestamps for PTP-1588
Published 2025-01-01“…By implementing an eCPRI packet processing unit based on the eCPRI Specification Version 2 and inspired by Intel’s FPGA-based IP, we enable modular addition of new message types and custom packet processing functionality in P4. Our approach reduced lines of code per type by 85% and decreased configuration time by up to 5x compared to traditional methods, significantly simplifying complexity. …”
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7059
Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer
Published 2024-11-01“…In this study, Chaga water extract was digested in vitro to mimic the natural processing and absorption of its biocomponents when it is consumed as functional beverage, and its anticancer activities were evaluated in breast cancer (BC) cell lines, representing HER2-positive and triple-negative subtypes. …”
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7060
IGF2BP3‐dependent N6‐methyladenosine modification of USP49 promotes carboplatin resistance in retinoblastoma by enhancing autophagy via regulating the stabilization of SIRT1
Published 2024-12-01“…We observed upregulation of USP49 in RB tissues and cell lines, correlating with disease progression. Functional assays revealed that USP49 promoted aggressive proliferation and conferred CBP resistance in RB cells. …”
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