Anti-Amyloid Aggregation Effects of Gobaishi (<i>Galla chinensis</i>) and Its Active Constituents by Sharmin Akter, Takayuki Tohge, Sahithya Hulimane Ananda, Masahiro Kuragano, Kiyotaka Tokuraku, Koji Uwai

“…Alzheimer′s disease (AD) is a chronic neurodegenerative disorder that leads to memory loss and changes in mental and behavioral functions in elderly individuals. A major pathological feature of AD is the aggregation of amyloid-beta (Aβ) peptides, along with oxidative stress, inducing neurocellular apoptosis in the brain. …”
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Versatile machine learning algorithms for FTIR spectroscopy: differentiating crosslinked and non-crosslinked gelatin samples by Juliana Rincón-López, Eliana Álvarez-Valdés, Daniela Velez-Arango, Estefanía Rojas Zuleta, Leidy Yuliana Vargas Soto, Liliana Lellesch, Victor Alonso García Londoño, Milton Rosero-Moreano, Gonzalo Taborda-Ocampo

“…This is a mixture of amino acid polymers with a variable molecular weight and a diversity of secondary structures (α, β and γ chains). The functional and mechanical properties of the gelatin depend on the chemical and structural characteristics. …”
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Valorization of Food Waste: Extracting Bioactive Compounds for Sustainable Health and Environmental Solutions by Nikša Bekavac, Korina Krog, Ana Stanić, Dunja Šamec, Anita Šalić, Maja Benković, Tamara Jurina, Jasenka Gajdoš Kljusurić, Davor Valinger, Ana Jurinjak Tušek

“…Utilizing food-derived polysaccharides as functional ingredients in the food, pharmaceutical, and cosmetics industries represents an environmentally friendly alternative to synthetic additives and is in line with global sustainability goals. …”
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A genome-wide association study reveals that DgFH18 and DgCMO-like are associated with flowering time in orchardgrass (Dactylis glomerata) by Miaoli Wang, Guangyan Feng, Zhongfu Yang, Lei Cao, Gang Nie, Xiaoheng Xu, Feixiang Hao, Linkai Huang, Xinquan Zhang

“…Furthermore, we validated that formin-like protein 18 (DgFH18) and choline monooxygenase (DgCMO-like) was two important flowering candidate genes by overexpressing them in Arabidopsis to unravel their potential functions. Overexpression of DgFH18 and DgCMO-like positively regulated flowering time by inducing the expression of flowering-related genes. …”
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Animal welfare parameters. A quality indicator of sheep slaughter in a province of Ecuador by Rafael Alfonso Garzón-Jarrín, Jorge Enrique Arellano-Yasaca, Lucia Monserrath Silva-Déley, Luis Alonso Chicaiza-Sánchez, Nancy Margoth Cueva Salazar

“…With reference to the evaluation of the personnel, 44 % indicated that there are trained personnel for the performance of their functions. It is concluded that the stress caused by deficient AW employment negatively affects the quality of the meat of the sheep slaughtered due to poor pre-mortem handling in the municipal slaughterhouse of Guamote, so it would be a priority to establish lines of work for the welfare of sheep destined for human consumption in the stages before, during and after slaughter, this will avoid the consequences of a poor process from transportation, housing, health, behavior, equipment management and exsanguination.…”
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Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity by Ying Zhang, Aiting Wang, Wei Zhao, Jia’an Qin, Yu Zhang, Bing Liu, Chengcheng Yao, Jianglan Long, Mingxia Yuan, Dan Yan

“…Metformin is the first-line pharmacotherapy for type 2 diabetes mellitus; however, many patients respond poorly to this drug in clinical practice. …”
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Epithelial-Mesenchymal Transition and Inflammation in Head and Neck Squamous Cell Carcinoma by Habib Sadeghi Rad, Abbas Shakoori Garakani, Ghodratolah Panahi, Saman Mehrabi, Mohammad reza Noori daloii

“…The current study aimed at investigating the mRNA expression of the three major factors in tumor specimens to define their functional and pathological roles in this malignancy. …”
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A suite of selective pressures supports the maintenance of alleles of a Drosophila immune peptide by Sarah R Mullinax, Andrea M Darby, Anjali Gupta, Patrick Chan, Brittny R Smith, Robert L Unckless

“…The innate immune system provides hosts with a crucial first line of defense against pathogens. While immune genes are often among the fastest evolving genes in the genome, in Drosophila, antimicrobial peptides (AMPs) are notable exceptions. …”
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Dynamic Real-Time Anchor Selection for Accurate UWB Indoor Positioning-Based Deep Neural Networks by Ammar Fahem Majeed, Rashidah Arsat, Muhammad Ariff Baharudin, Nurul Mu'Azzah Abdul Latiff, Abbas Albaidhani

“…By integrating multi-scale feature extraction, sequential learning, and advanced activation functions with the conventional linearized least squares method, the LSB-DIP Net enables robust, accurate, and dynamic UWB positioning in real-time. …”
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RAW264.7 Macrophages as a Polarization Model in the Context of Pancreatic Cancer and Chemokine Release by Aydar Khabipov, Lea Miebach, Maik Lenz, Stephan Kersting, Sander Bekeschus

“…Collectively, we demonstrated that our model is suitable for testing the roles and functions of chemokines in macrophage polarization by pancreatic cancer cells.…”
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Salicylic Acid-Induced Expression Profiles of LRR and LRR-RLK Candidate Genes Modulate <i>Mungbean Yellow Mosaic India Virus</i> Resistance in Blackgram and Its Two Wild Non-Progen... by Mansi Shukla, Priyanka Kaundal, Shalini Purwar, Mukul Kumar, Chandragupt Maurya, Chirag, Awdhesh Kumar Mishra, Kwang-Hyun Baek, Chandra Mohan Singh

“…The analysis provides insight into the diversity and robust candidate genes for functional studies modulating YMD resistance altered by salicylic acid.…”
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Transcriptomics-informed pharmacology identifies epigenetic and cell cycle regulators that enhance AAV production by Joshua Tworig, Francis Grafton, Kaylin Fisher, Markus Hörer, Christopher A. Reid, Mohammad A. Mandegar

“…We also saw upregulation of several core functions, including transcription, stress response, and Golgi and endoplasmic reticulum organization. …”
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Multi-Hazard Vibration Control of Transmission Infrastructure: A Pounding Tuned Mass Damper Approach with Lifelong Reliability Analysis by Zhuoqun Zhang, Lizhong Qi, Jingguo Rong, Yaping Zhang, Peijie Li, Ziguang Jia

“…Power transmission tower-line systems are exposed to various dynamic hazards, including wind and earthquakes, among others. …”
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Overexpression of plasma membrane SUT1 in poplar alters lateral sucrose partitioning in stem and promotes leaf necrosis by Liang‐Jiao Xue, Moh'd I. Hozain, Christopher J. Frost, Afraz Talebi, Batbayar Nyamdari, Kavita B. Aulakh, Ran Zhou, Scott A. Harding, Chung‐Jui Tsai

“…However, plasma membrane sucrose transporters (SUT1 and SUT3) orthologous to those associated with apoplastic phloem loading are expressed in vascular tissues of poplar. While SUT3 functions in sucrose import into developing xylem, the role of SUT1 remains unclear. …”
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Elucidating the role of CYFIP2 in conferring cisplatin resistance in esophageal squamous cell carcinoma by Peipei Zhang, Weiguang Zhang, Zhinuan Hong, Junfei Jiang, Ningzi Wu, Jihong Lin, Mingqiang Kang

“…Empirical validation was achieved by treating ESCC cell lines with CDDP, which resulted in an upsurge of CYFIP2 expression. …”
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Full-length transcriptome atlas of gallbladder cancer reveals trastuzumab resistance conferred by ERBB2 alternative splicing by Ziyi Wang, Li Gao, Ziheng Jia, Liguo Liu, Ao Gu, Zhaonan Liu, Qin Zhu, Yichen Zuo, Mingjie Yang, Shijia Wang, Jiyao Ma, Jingyun Zhang, Shimei Qiu, Zhizhen Li, Jinghan Wang, Dongxi Xiang, Fatao Liu, Rong Shao, Yanjing Li, Maolan Li, Wu Wei, Yingbin Liu

“…A novel transcript, designated ERBB2 i14e, was identified for encoding a novel functional protein, and its protein expression was elevated in gallbladder cancer and strongly associated with worse prognosis. …”
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Isoliensinine Induces Ferroptosis in Urothelial Carcinoma Cells via the PI3K/AKT/HIF-1α Axis: Molecular Evidence from Next-Generation Sequencing by Yun-Chen Li, Hsuan-En Huang, Chia-Ying Yu, Ya-Chuan Chang, Shu-Yu Lin, Shao-Chuan Wang, Wen-Wei Sung

“…RNA sequencing analysis, performed to explain the underlying mechanisms, revealed a significant regulation of cell functions, including apoptosis, the cell cycle, hypoxia-inducible factor 1 (HIF-1) signaling, tumor necrosis factor (TNF) signaling, and ferroptosis. …”
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Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis by Tingji Yang, Bo Fang, Yan Chen, Dan Bao, Jiang Zhang, Peiwen Liu, Zhiwei Duan, Yuxuan He, Xingxu Zhao, Quan-Wei Zhang, Wei-Tao Dong, Yong Zhang

“…This study aims to use lipopolysaccharide (LPS) to establish mammary alveolar cells-large T antigen cells (MAC-T is a bovine mammary epithelial cell line) and mouse models of mastitis, investigating the functional relationship between actin-related protein 2/3 complex subunits 3 (ARPC3) and 4 (ARPC4) and heat shock protein 70 (HSP70) during mammary epithelial cell inflammation and assessing its effects on apoptosis. …”
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mRNA‐Engineered CD5‐CAR‐γδTCD5‐ Cells for the Immunotherapy of T‐Cell Acute Lymphoblastic Leukemia by Zhixiong Zhu, Hexian Li, Qizhong Lu, Zongliang Zhang, Jia Li, Zeng Wang, Nian Yang, Zhengyu Yu, Chen Yang, Yongdong Chen, Huaqing Lu, Wei Wang, Ting Niu, Chunlai Nie, Aiping Tong

“…IVT‐mRNA‐CD5‐CAR‐γδTCD5− cells exhibited favorable functional characteristics and demonstrated antitumor efficacy against malignant T cell lines, underlining the potential for advancing mRNA‐CD5‐CAR‐γδTCD5− therapy.…”
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IUPAC International Chemical Identifier (InChI)-related education and training materials through InChI Open Education Resource (OER) by Cornell Andrew P., Kim Sunghwan, Cuadros Jordi, Bucholtz Ehren C., Pence Harry E., Potenzone Rudy, Belford Robert E.

“…Currently, the OER contains over 100 materials collected from various sources and provides users with search, filtering, and sorting functionalities to locate specific records. New relevant materials can be suggested by anyone, allowing the scientific community to share and find InChI-related resources. …”
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