GenMasterTable: a user-friendly desktop application for filtering, summarising, and visualising large-scale annotated genetic variants by Jing Zhai, Nelly Pitteloud, Federico A. Santoni

“…As the first tool to enable comprehensive cohort-level analysis from VCF, CSV to TSV files, GenMasterTable provides advanced functionality for concatenation, filtering, summarizing, and visualizing large-scale annotated datasets. …”
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Patient Perspectives of Dignity, Autonomy and Control at the End of Life: Systematic Review and Meta-Ethnography. by Andrea Rodríguez-Prat, Cristina Monforte-Royo, Josep Porta-Sales, Xavier Escribano, Albert Balaguer

“…Three themes emerged: a) dignity mediated by the loss of functionality, linked to the loss of control; b) dignity as identity; and c) autonomy as a determining factor of perceived dignity, understood as the desire for control over the dying process and the desire for self-determination. …”
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The Influence of Music Producing and Creativity on Computational Thinking in Primary School Children by Nardie Fanchamps, Emily Van Gool, Anna Folkertsma, Kim De Meyst

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The Social Science Students’ Scientific Societies: Historical Experience and Current Trends by Aleksandra Yurievna Gorchakova, Ekaterina Aleksandrovna Semerova, Alexander Vasilyevich Labudin

“…The authors insist: exactly in correctly functioning students’ scientific society each pupil will learn to think unconventionally and creatively respond to the challenges of time. …”
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Improved MViTv2-T model for insulator defect detection by Fuhong Meng, Guowu Yuan, Hao Zhou, Hao Wu, Yi Ma

“…Insulators play a crucial role in transmission lines. Insulators exposed to natural environments are prone to various malfunctions. …”
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Small GTPase ARL4C Associated with Various Cancers Affects Microtubule Nucleation by Evgeniia Ulas, Ilya Brodsky, Anton Burakov

“…Although ARL4C can bind alpha-tubulin and affect intracellular transport, the role of ARL4C in the functioning of the tubulin cytoskeleton remained unclear. …”
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Combining real-world data with randomized controlled trials results in better information oncology decision making by T. A. Usmanova, E. V. Verbitskaya

“…These publications» authors show that real-world patients are older, have worse functional status, and have a greater number of comorbidities. …”
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Coupling circuit design for Single-Wire Earth Return PLC applications through cascaded s-parameters optimization by Kristi Beqirllari, Cagil Ozansoy, Douglas Gomes

“…The proposed method has been applied to different cost functions and different levels of target mean error. …”
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Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis by Rui Li, Jianquan Liu, Liuxun Li, Guotian Luo, Xinrong Yuan, Shichao Shen, Yongpeng Shi, Jianlong Wu, Bin Yan, Lei Yang

“…Using peripheral nerve injury model rats treated with porcine decellularized nerve matrix hydrogel, we evaluated structural and functional recovery, macrophage phenotype alteration, specific cytokine expression, and changes in related signaling molecules in vivo. …”
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Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals. by Monta Briviba, Ivars Silamikelis, Ineta Kalnina, Laura Ansone, Vita Rovite, Ilze Elbere, Ilze Radovica-Spalvina, Davids Fridmanis, Jekaterina Aladyeva, Ilze Konrade, Valdis Pirags, Janis Klovins

“…This inter-individual variation of the metformin effect on the transcriptional regulation goes in line with well-known variability of the therapeutic response to the drug.…”
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Caco2/HT-29 In Vitro Cell Co-Culture: Barrier Integrity, Permeability, and Tight Junctions’ Composition During Progressive Passages of Parental Cells by Elena Donetti, Paola Bendinelli, Margherita Correnti, Elena Gammella, Stefania Recalcati, Anita Ferraretto

“…Epithelial linings are crucial for the maintenance of physiological barriers. …”
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NOTCH1 promotes the elevation of GM-CSF and IL-6 through the EZH2/STAT3 pathway to facilitate the fibrotic state of the myocardium in DLBCL. by Huimin Zhang, Wen Dong, Lihong Zhang, Bing Ma, Jianying Wang, Yang Shen, Dan Zhao, Wanyi Yin, Yuexian Li, Qingchi Liu

“…Various assays were conducted including stable cell line construction, myocardial infarction modeling, imaging, Western Blot, ELISA, staining, and functional assays.…”
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Fracture toughness and microstructural analysis of rotary friction welded S355J2 and SS316L steels for critical applications by Rajkumar Das, Giribaskar Sivaswamy, Himanshu Lalvani, Ajit Pal Singh

“…The fracture toughness (KQ) matched parent metal values, with the RFW weld centre line (WCL) showing superior crack tip opening displacement (CTOD) of 0.35 mm. …”
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Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy. by Nada Hradilova, Lenka Sadilkova, Ondrej Palata, Dagmar Mysikova, Hana Mrazkova, Robert Lischke, Radek Spisek, Irena Adkins

“…Moreover, DC-based HHP lung cancer vaccine showed functional plasticity after transfer into serum-containing media and stimulation with LPS or CD40L after additional 24h. …”
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Inhibition of Allogeneic and Autologous T Cell Proliferation by Adipose-Derived Mesenchymal Stem Cells of Ankylosing Spondylitis Patients by Ewa Kuca-Warnawin, Magdalena Plebańczyk, Krzysztof Bonek, Ewa Kontny

“…In ankylosing spondylitis (AS), accompanied by chronic inflammation, T cell expansion plays a pathogenic role; the immunoregulatory properties of bone marrow-derived mesenchymal stem cells (BM-MSCs) are impaired, while functional characteristics of their adipose tissue-derived counterparts are (ASCs) unknown. …”
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Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection. by Tomoki Yoshikawa, Terence E Hill, Naoko Yoshikawa, Vsevolod L Popov, Cristi L Galindo, Harold R Garner, C J Peters, Chien-Te Kent Tseng

“…Based on microarray-based functional genomics, we report here the global gene response of 2B4 cells, a cloned bronchial epithelial cell line derived from Calu-3 cells. …”
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The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cells. by Yang Shi, Can Liu, Xin Liu, Dean G Tang, Junchen Wang

“…Recently, miR-34a was found to be downregulated in NSCLC cells but the biological functions of miR-34a in regulating NSCLC cell behavior have not been extensively studied. …”
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SNW1 is a critical regulator of spatial BMP activity, neural plate border formation, and neural crest specification in vertebrate embryos. by Mary Y Wu, Marie-Christine Ramel, Michael Howell, Caroline S Hill

“…Through a large-scale in vivo functional screen in Xenopus for neural crest fate, we identified an essential regulator of BMP activity, SNW1. …”
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A Fast, Simple, and Approximate Method for a Minimal Unit Cell Design of Glide-Symmetric Double-Corrugated Parallel-Plate Waveguides by Fatih Çolak, Agah Oktay Ertay

“…This paper introduces a novel design methodology based on the auxiliary functions of generalized scattering matrix (AFGSM) for the dimensional synthesis of GS-DCPPWs. …”
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Operative calculation of electric power losses in the network with unknown parameters in AIMS EMA by M. I. Danilov, I. G. Romanenko

“…The proposed methodology can be used in existing AIMS EMA without the introduction of additional measuring means (functions).…”
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