A versatile framework for attitude tuning of beamlines at light source facilities by Peng-Cheng Li, Xiao-Xue Bi, Zhen Zhang, Xiao-Bao Deng, Chun Li, Li-Wen Wang, Gong-Fa Liu, Yi Zhang, Ai-Yu Zhou, Yu Liu

“…It supports flexible input/output ports, easy integration of diverse evaluation functions and free selection of optimization algorithms. …”
Get full text

Beneficial Effects of Rosmarinic Acid on IPEC-J2 Cells Exposed to the Combination of Deoxynivalenol and T-2 Toxin by Judit Mercédesz Pomothy, Réka Fanni Barna, Erzsébet Anna Pászti, Ákos Babiczky, Áron Szóládi, Ákos Jerzsele, Erzsébet Pásztiné Gere

“…Deoxynivalenol (DON) and T-2 toxin (T-2) are major trichothecene mycotoxins and are known to challenge mainly intestinal barrier functions. Polyphenolic rosmarinic acid (RA) appeared to have antioxidant and anti-inflammatory properties in vitro. …”
Get full text

Estramustine Phosphate Inhibits TGF-β-Induced Mouse Macrophage Migration and Urokinase-Type Plasminogen Activator Production by Sonja S. Mojsilovic, Slavko Mojsilovic, Suncica Bjelica, Juan F. Santibanez

“…We found out that, in the murine macrophage cell line RAW 264.7, EP at noncytotoxic concentrations inhibited cell migration and uPA expression induced by TGF-β. …”
Get full text

miR-146a-5p suppresses migration and downregulates vimentin and MMP-9 expression in gastric cancer cells by Amir Baghbanzadeh, Shima Rahmani, Sahand Eslami, Mahya Ahmadpour Youshanlui, Nadia Shafiee, Atefe Shafiee, Amirreza Khalaji, Behzad Baradaran

“…This study investigates the role of microRNA-146a-5p (miR-146a-5p) in regulating migration and invasion of KATO III GC cells by targeting vimentin and matrix metalloproteinase-9 (MMP-9), critical mediators of epithelial–mesenchymal transition (EMT). miR-146a-5p expression was analyzed in GC cell lines, and functional assays were performed after transfection with a miR-146a-5p mimic. …”
Get full text

Cell Wall Invertase 4 Governs Sucrose–Hexose Homeostasis in the Apoplast to Regulate Wood Development in Poplar by Jing Lu, Qiao Ren, Qilin Wang, Yaqi Wen, Yanhong Wang, Ruiqi Liang, Dingxin Ran, Yifeng Jia, Xinyu Zhuo, Jiangtao Luo, Xianqiang Wang, Keming Luo

“…In perennial trees, wood development is a carbon-demanding process, pivotal for secondary cell wall (SCW) formation and xylem development. Sugars, functioning both as carbon substrates and signaling molecules, orchestrate cambial proliferation and xylem differentiation. …”
Get full text

Membrane tubulation induced by a bacterial glycolipid by Kaoru Nomura, Akihiro Tsuji, Hayato Yamashita, Masayuki Abe, Kohki Fujikawa, Shoko Mori, Tsukiho Osawa, Hiromi Toyonaga, Tomohiro Osugi, Kazuma Yasuhara, Kenichi Morigaki, Ken-ichi Nishiyama, Keiko Shimamoto

“…These findings provide insights into the mechanism underlying glycolipid-induced membrane tubulation and suggest that the unique long sugar chain of MPIase can offer functions beyond its essential role in membrane protein integration.…”
Get full text

A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury by Wei Gong, Haiyan Zhu, Li Lu, Yayi Hou, Huan Dou

“…Macrophages have variable functional phenotypes, high diversity, and plasticity and are involved in the pathogenesis of sepsis-induced liver injury. …”
Get full text

Advances in Novel Diagnostic Techniques for Alveolar Echinococcosis by Huanhuan Liu, Yijia Xie, Xiaoyu An, Dazhuang Xu, Shundong Cai, Chengchao Chu, Gang Liu

“…US is often the first-line method due to its non-invasiveness and cost-effectiveness, but it may have limitations in assessing complex lesions. …”
Get full text

Simulation-based assessment of digital twin systems for immunisation by Leonardo de Oliveira El-Warrak, Claudio Miceli de Farias, Victor Hugo Dias Macedo De Azevedo Costa

“…BackgroundThis paper presents the application of simulation to assess the functionality of a proposed Digital Twin (DT) architecture for immunisation services in primary healthcare centres. …”
Get full text

Large-scale CRISPRi screens link metabolic stress to glioblastoma chemoresistance by Xing Li, Wansong Zhang, Yitong Fang, Tianhu Sun, Jian Chen, Ruilin Tian

“…Findings were validated using multiple GBM cell lines, patient-derived glioma stem cells, and clinical data. …”
Get full text

Antimicrobial and biodegradable hydrogel based on nanocellulose/alginate incorporated with silver nanoparticles as active packaging for poultry products by Noppon Somsesta, Apichart Jinnapat, Supachai Fakpiam, Chanchai Suksanguan, Varan Wongsan, Wassikah Ouneam, Supisara Wattanaeabpun, Intatch Hongrattanavichit

“…AgH was characterized in terms of basic properties, functional properties, and packaging applications. Biocompatibility testing with the Caco-2 cell line showed that higher concentrations of silver (higher than 0.0312 phr) provided a lower cell viability rate (lower than 70% cell viability). …”
Get full text

UBE4B promotes gastric cancer proliferation and metastasis by mediating FAT4 ubiquitination and degradation by Kaini Wu, Zixiang Guo, Yunfeng Fu, Sicheng Yang, Yating Pan, Runwei Yan, Xiaodong Zhou

“…The aim of this study was to reveal the functional significance of UBE4B in gastric cancer (GC) development and its important mechanism. …”
Get full text

Addendum to How Small Can S-boxes Be? by Yu Sun, Lixuan Wu, Chenhao Jia, Tingting Cui, Kai Hu, Meiqin Wang

“… In ToSC 2025(1), Jia et al. proposed an SAT-aided automatic search tool for the S-box design. A part of the functionality of this tool is to search for implementations of an S-box with good area and gate-depth complexity. …”
Get full text

Accelerating Stellar Photometric Distance Estimates with Neural Networks by Karlo Mrakovčić, Željko Ivezić, Lovro Palaversa

“…We present an analysis of pipeline performance, including speed and biases as functions of input stellar parameters and signal-to-noise ratio, using TRILEGAL-based simulated LSST catalogs by P. …”
Get full text

Insights into eutectic formation and photodynamic therapeutic effects produced by folic acid on wound healing by an allantoin-fructose system by Syed Waqar Hussain Shah, Amara Ayub, Iram Bibi, Muhammad Ijaz, Obaid ur Rahman Abid, Kashif Ali

“…Solid–liquid binary phase diagram showed a differential melting depression of 88°C from the ideal line and the existence of eutectic at X1 = X2 = 0.5. …”
Get full text

Multimodal prediction of the need of clozapine in treatment resistant schizophrenia; a pilot study in first-episode psychosis by Jonatan M. Panula, Athanasios Gotsopoulos, Jussi Alho, Jaana Suvisaari, Maija Lindgren, Tuula Kieseppä, Tuukka T. Raij

“…As many as one third of the patients diagnosed with schizophrenia do not respond to first-line antipsychotic medication. This group may benefit from the atypical antipsychotic medication clozapine, but initiation of treatment is often delayed, which may worsen prognosis. …”
Get full text

Diagnosis and Treatment of Elderly and Senile Chronic Constipation: an Expert Consensus by V. T. Ivashkin, M. G. Mnatsakanyan, V. S. Ostapenko, А. P. Pogromov, V. M. Nekoval, E. A. Poluectova, Yu. V. Kotovskaya, N. K. Runikhina, N. V. Sharashkina, P. V. Tsarkov, N. O. Tkacheva, Yu. N. Belenkov

“…The treatment tactics in chronic constipation is cause-conditioned and should account for the patient’s history and therapy line, overall clinical condition, cognitive status and functional activity level. …”
Get full text

Optimal Location Model of Bus Terminals and Evaluation of Factors Affecting It by Morteza Shafiee, Hilda Saleh, Aseyeh Sadat Hatami

“…Purpose: Terminals are major urban passenger centers that play an essential role in collecting and distributing demand on the network. The proper functioning of terminals depends on their adequate planning, a necessary part of which is devoted to their principled location. …”
Get full text

Disentangling High-Paced Alternating I/O in Gaze-Based Interaction by Yulia G. Shevtsova, Artem S. Yashin, Sergei L. Shishkin, Anatoly N. Vasilyev

“…” However, gaze should also support information flow in the opposite direction, namely, “input” to the user’s visual system from a machine’s output. The two functions can be easily separated in some tasks, like eye typing, but more complex scenarios typically require users to perform additional actions to avoid misinterpreting their intent. …”
Get full text

Can the nutritional geometric framework unveil how macronutrients in pollen shape solitary bee foraging and survival? by Jaya Sravanthi Mokkapati, Natalie Boyle, Pierre Ouvrard, Adrien Sicard, Christina M. Grozinger

“…In a semi-field experiment using Capsella recombinant inbred plant lines with varying pollen protein-to-lipid (P : L) ratios, M. rotundata visits were positively associated with pollen protein content. …”
Get full text