Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat by Jean Pierre Munyaneza, Minjun Kim, Eunjin Cho, Aera Jang, Hyo Jun Choo, Jun Heon Lee

“…The objective of this study was to identify functional candidate genes for fatty acid profiles of the breast meat of the Korean native chicken-red-brown line (KNC-R) through genome-wide association studies. …”
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Comparison of Vernier Acuity Measured with Three Different Water-induced Blur Simulation Methods by Vivek Suganthan Ramasubramanian, Aiswaryah Radhakrishnan

“… Purpose: Human vision is subnormal in an aquatic environment, and studies have used different methods to measure visual functions with water-induced blur (WIB). In this study, we compared vernier acuity measured using three different WIB simulation methods. …”
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In Vivo Chromatin Targets of the Transcription Factor Yin Yang 2 in Trophoblast Stem Cells. by Raquel Pérez-Palacios, Sofía Macías-Redondo, María Climent, Bruno Contreras-Moreira, Pedro Muniesa, Jon Schoorlemmer

“…YY1 is a DNA-binding transcription factor, with defined functions in multiple developmental processes, such as implantation, cell differentiation, X inactivation, imprinting and organogenesis. …”
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Induced collagen type‐I secretion by hepatocytes of the melanoma liver metastasis is associated with a reduction in tumour‐infiltrating lymphocytes by Shodai Mizuno, Matias A. Bustos, Yoshinori Hayashi, Kodai Abe, Satoru Furuhashi, Yalda Naeini, Xiaowei Xu, Anton J Bilchik, Dave S. B. Hoon

“…Methods Hepatocytes and melanoma tumour cells of MLiM were assessed using transcriptomic NanoString GeoMx digital spatial profiling (NGDSP) assay. Functional assays were performed using normal hepatocytes and MLiM‐derived cell lines. …”
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Circulating innate lymphoid cells are dysregulated in patients with prostate cancer by Daniela Claudia Maresca, Evelina La Civita, Benedetta Romano, Maria Rosaria Ambrosio, Fabio Somma, Tania Wyss, Bernardo Rocco, Valentina Rubino, Luigi Cari, Philippe Krebs, Antonio Rodriguez-Calero, Matteo Ferro, Sara Trabanelli, Camilla Jandus, Felice Crocetto, Angela Ianaro, Daniela Terracciano, Giuseppe Ercolano

“…This study investigated the phenotypic and functional profiles of ILC subsets in the peripheral blood mononuclear cells (PBMCs) of patients with PCa stratified by Gleason score. …”
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Identification of anoikis-related molecular patterns and the novel risk model to predict prognosis, tumor microenvironment infiltration and immunotherapy response in bladder cancer by Luochen Zhu, Feng Xiao, Yi Hou, Shenjun Huang, Yanyan Xu, Xiaohong Guo, Xinwei Dong, Chunlu Xu, Xiaolei Zhang, Haijuan Gu

“…In addition, representative genes were evaluated using immunohistochemistry in clinical specimens, and in BLCA cell lines, functional experiments were performed to determine the biological behavior of hub gene PLOD1.ResultTwo definite anoikis subgroups were identified. …”
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Evaluation of the Immunostimulant Effect of Microvesicles of <i>Lactobacillus acidophilus</i> Isolated from Wild Rats by Pamela I. Pérez-Martínez, Viridiana Gutiérrez-Espinosa, Christian Ávalos-Gómez, Mireya De la Garza-Amaya, Alejandro Vargas-Ruíz, Rosa I. Higuera-Piedrahita, Ernesto Marín-Flamand, Cristal D. Lonngi-Sosa, Francisco R. González-Díaz, Hugo Ramírez-Álvarez, Cynthia González-Ruíz

“…It is capable of releasing membrane microvesicles (MVs), whose primary functions include carrying and transmitting antigens to host tissues and modulating host defense responses. …”
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Aging-associated DNA methylation of LEF1 modulates inflammation and neurodegenerative pathways by Mengke Chen, Mengke Chen, Lujie Zhou, Yidan Gao, Yao Zhong, Cheng Chen, Zhicheng Wang, Xiaoning Wang, Rong Xia

“…Transcriptomics and chromatin immunoprecipitation sequencing (ChIP-Seq) were conducted to explore potential regulatory mechanisms. Functional validation was performed via knockdown in immune and microglial cell lines, assessing inflammatory responses and reactive oxygen species (ROS) levels. …”
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A Generic Modeling Method of Multi-Modal/Multi-Layer Digital Twins for the Remote Monitoring and Intelligent Maintenance of Industrial Equipment by Maolin Yang, Yifan Cao, Siwei Shangguan, Xin Chen, Pingyu Jiang

“…The model was verified through three different DT modeling scenarios of a robot-based carbon block polishing processing line.…”
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A Broadband Distributed Vibration Sensing System Assisted by a Distributed Feedback Interferometer by Yuanyuan Shan, Jiayun Dong, Jie Zeng, Siyi Fu, Yinsen Cai, Yixin Zhang, Xuping Zhang

“…Both functions of &#x03A6;-OTDR and DFI could work synchronously without influence between each other. …”
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GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer by Yongchang Zheng, Yue Shi, Si Yu, Yuanyuan Han, Kai Kang, Haifeng Xu, Huajian Gu, Xinting Sang, Yang Chen, Jingyu Wang

“…To investigate underlying molecular mechanism, we generated GTSE1 knockdown HCC cell line and explored the effects of GTSE1 deficiency in cell growth. …”
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Anthocyanins and phenolic compounds in colored wheat grain by E. V. Chumanova, T. T. Efremova, K. V. Sobolev, E. A. Kosyaeva

“…Special attention in the review is paid to the description of achievements of Russia’s breeders in developing promising varieties and lines with colored grain, which will be a key factor in expanding the opportunities of the domestic and international grain market.…”
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A fusion ORF3a-E subgenomic RNA involved in SARS-CoV-2 infection efficacy by influencing cellular protein synthesis by Yifan Zhang, Jing Li, Xinglong Zhang, Xin Zhang, Jiali Li, Heng Li, Heng Li, Heng Li, Xin Zhao, Xin Zhao, Xin Zhao, Zihan Zhang, Yingyan Li, Keqi Chen, Shasha Peng, Haijing Shi, Haijing Shi, Haijing Shi, Longding Liu, Longding Liu, Longding Liu

“…Subgenomic RNAs (sgRNAs) are discontinuous transcription products of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are involved in viral gene expression and replication, but their exact functions are still being studied. Here, we report the identification of a nested ORF3a-sgRNA, the fusion ORF3a-E-sgRNA, which is involved in the infection process of SARS-CoV-2. …”
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Deletion of Pyruvate Carboxylase in Tubular Epithelial Cell Promotes Renal Fibrosis by Regulating SQOR/cGAS/STING‐Mediated Glycolysis by Hao Huang, Yuanyuan Han, Yan Zhang, Jianhua Zeng, Xin He, Jiawei Cheng, Songkai Wang, Yiwei Xiong, Hongling Yin, Qiongjing Yuan, Ling Huang, Yanyun Xie, Jie Meng, Lijian Tao, Zhangzhe Peng

“…This leads to mitochondrial morphological and functional disruption, increased mtDNA release, activation of the cGAS‐STING pathway, and elevated glycolysis levels, and ultimately, promotes renal fibrosis. …”
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Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews by Tobias Braun, Patrick J Owen, Daniel L Belavy, Christian Kopkow, Toni Lange, Tobias Saueressig, Rilind Shala, Jochen Zebisch, Kerstin Lüdtke, Andres Jung, Katja Ehrenbrusthoff, Rebekka Döding, Bernhard Elsner, Clint Miller, Axel Schäfer, Robin Schäfer, Tim Schleimer, Tibor Szikszay

“…Conservative non-pharmacological interventions play a first-line role in the treatment and management of most NCDs. …”
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A novel plasma circular RNA circFARSA is a potential biomarker for non‐small cell lung cancer by Dong Hang, Jing Zhou, Na Qin, Wen Zhou, Hongxia Ma, Guangfu Jin, Zhibin Hu, Juncheng Dai, Hongbing Shen

“…Bioinformatics and functional analyses were performed to reveal biological effects of circRNAs on lung cancer cells. …”
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Remimazolam induced cytotoxicity mediated through multiple stress pathways and acted synergistically with tyrosine kinase inhibitors in hepatocellular carcinoma by Hsiu-Lung Fan, Jia-Lin Chen, Shu-Ting Liu, Jia-Tong Lee, Shih-Ming Huang, Zhi-Fu Wu, Hou-Chuan Lai

“…Our combination index revealed that remimazolam besylate has the potential to act as a sensitizer for targeted tyrosine kinase inhibitor therapy for HCC.Discussion: Our findings open up new possibilities for combinatory HCC therapy using remimazolam, leveraging its dual functional roles in surgery and drug therapy for liver cancers.…”
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BaCoN (Balanced Correlation Network) improves prediction of gene buffering by Thomas Rohde, Talip Yasir Demirtas, Sebastian Süsser, Angela Helen Shaw, Manuel Kaulich, Maximilian Billmann

“…Abstract Buffering between genes, where one gene can compensate for the loss of another gene, is fundamental for robust cellular functions. While experimentally testing all possible gene pairs is infeasible, gene buffering can be predicted genome-wide under the assumption that a gene’s buffering capacity depends on its expression level and its absence primes a severe fitness phenotype of the buffered gene. …”
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Mining of Candidate Genes and Developing Molecular Markers Associated with Pokkah Boeng Resistance in Sugarcane (<i>Saccharum</i> spp.) by Haidong Lin, Zhengjie Jiang, Tuan He, Guomeng Li, Mengyu Zhao, Liangyinan Su, Jihan Zhao, Chengwu Zou, Xiping Yang

“…Utilizing weighted gene co-expression network analysis (WGCNA), we identified gene modules closely related to disease phenotypes. We annotated their functions with bioinformatics tools, particularly focusing on genes enriched in the plant immune response’s MAPK signaling pathway and ABC transporter synthesis pathways. …”
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Genetic basis of Fusarium ear rot resistance and productivity traits in a heterozygous multi-parent recombinant inbred intercross (RIX) maize population by Shree Prasad Neupane, Lorenzo Stagnati, Matteo Dell’Acqua, Matteo Busconi, Alessandra Lanubile, Mario Enrico Pè, Leonardo Caproni, Adriano Marocco

“…This was achived by crossing pairs of recombinant inbred lines (RILs) derived from a multi-parent maize population. …”
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