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6541
Hierarchical Regulatory Networks Reveal Conserved Drivers of Plant Drought Response at the Cell‐Type Level
Published 2025-05-01“…Experimental validation in Arabidopsis thaliana and Vitis vinifera confirms the functional conservation of CIPK23, which enhances drought resistance in overexpression lines. …”
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6542
Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia
Published 2025-02-01“…We performed histological and functional analyses in native and air-liquid interface (ALI) cultured respiratory cells. …”
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6543
Potential of Stem-Cell-Induced Peripheral Nerve Regeneration: From Animal Models to Clinical Trials
Published 2024-11-01“…The plasticity and inducibility of stem cells make them an enticing option for initiating neuronal cell regrowth and optimal sensory and functional nerve regeneration. Peripheral nerve injury has a broad range of causative factors and etiologies. …”
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6544
Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature
Published 2025-03-01“…Here, we report a case where Ossifying Fibroma (OF) was diagnosed in an adolescent female patient and was treated by marginal mandibular resection to avoid esthetic and functional defects in the future. Case presentation OF was diagnosed in a 13-year-old woman incidentally. …”
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6545
Mapping growth and trajectory in the field of extracellular vesicles: A scientometric analysis
Published 2025-06-01“…They play roles in a variety of diseases and biological functions, piquing the interest of researchers and industry alike. …”
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6546
Pangenome analysis of transposable element insertion polymorphisms reveals features underlying cold tolerance in rice
Published 2025-08-01“…Our TIP-GWAS analysis reveal two cold tolerance genes OsCACT and OsPTR. The biological functions of these genes are confirmed using knockout and overexpression lines. …”
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6547
Successful surgical treatment of mediastinal lung hernia with a mesh implant. Consequent results
Published 2023-05-01“…As a result of treatment, after 3 years, radiologically stable restoration of the position of the only right lung in its hemithorax. The patient is functionally compensated, shortness of breath is not observed. …”
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6548
Glypican 3 as target therapy to prevent cell migration and proliferation in rhabdomyosarcoma
Published 2025-07-01“…Functional assays were performed with the antineoplastic drug doxurubicin and the WNT3a inhibitor, ipafricept. …”
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6549
Micro‐Scale Topography Triggers Dynamic 3D Nuclear Deformations
Published 2025-03-01“…Finally, it is demonstrated that myoblasts from laminopathy patients exhibit abnormal nuclear deformations on microgrooves, raising the possibility of using microgroove substrates as a novel functional diagnostic platform for pathologies that involve abnormal nuclear mechanics.…”
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6550
Whole Genome Sequencing of Greater Amberjack (Seriola dumerili) for SNP Identification on Aligned Scaffolds and Genome Structural Variation Analysis Using Parallel Resequencing
Published 2018-01-01“…We carried out de novo sequencing of the greater amberjack genome to construct a reference genome sequence to identify single nucleotide polymorphisms (SNPs) for breeding amberjack by marker-assisted or gene-assisted selection as well as to identify functional genes for biological traits. We obtained 200 times coverage and constructed a high-quality genome assembly using next generation sequencing technology. …”
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6551
A novel genome‐wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT‐TCF pathway modulators TMED3 and SOX12
Published 2014-06-01“…Abstract The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays do not fully predict metastatic behavior, and the majority of studies have used cloned cell lines, which do not reflect primary tumor heterogeneity. …”
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6552
Multifunctional Reconfigurable Millimeter-Wave Array Antenna
Published 2025-01-01“…This paper presents the design and implementation of an innovative 4-element multifunctional reconfigurability array antenna (MRAA) operating at 27.5 GHz, leveraging PIN diodes for enhanced functionality. By strategically controlling the alignment of PIN diodes, the antenna utilizes only two coplanar strip line biasing networks, streamlining its design and implementation. …”
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6553
Chromosome-level genome assembly and annotation of the pygmy grasshopper Gibbotettix parvipulvillus
Published 2025-07-01“…Repeat annotation revealed repetitive elements comprise 58.79% of the genome, with LINEs being most abundant (14.15%). We annotated 17,220 protein-coding genes with functional information assigned to 93.82% of them. …”
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6554
X-Band Waveguide Mechanical Damper Enabled by 3D Printed Flexible Corrugations and Dielectric Loaded Chokes
Published 2025-01-01“…The dielectric-loaded RF chokes also provide mechanical functionality of the waveguide mechanical damper by implementing corrugations as part of the choke design, allowing for shocks and acceleration to 20G. …”
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6555
Total Penetrating Keratoplasty: Indications, Therapeutic Approach, and Long-Term Follow-Up
Published 2018-01-01“…Evaluation of the indications, anatomical and functional results, and complications of total penetrating keratoplasty (TPK) in disorders involving whole cornea. …”
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6556
Phthalates promote lenvatinib resistance in hepatocellular carcinoma through the HPX-MAPK pathway
Published 2025-09-01“…HPX was highlighted as a central gene that interacts strongly with diethyl, dimethyl, and dioctyl phthalates and is significantly downregulated in HCC tissues and resistant cell lines. Functional assays revealed that HPX suppresses HCC cell proliferation, migration, invasion, and lenvatinib resistance, and its overexpression enhances drug sensitivity. …”
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6557
Intestinal epithelial Gasdermin C is induced by IL-4R/STAT6 signaling but is dispensable for gut immune homeostasis
Published 2024-11-01“…Here, we tested the functional role of Gasdermin C in intestinal homeostasis, inflammation and tumorigenesis. : We studied Gasdermin C in response to cytokines in intestinal organoids. …”
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6558
Quantification of human angiogenesis in immunodeficient mice using a photon counting-based method
Published 2007-07-01“…Here, we engineered human blood vessels in immunodeficient mice with human endothelial cells expressing luciferase, demonstrated that these cells line functional blood vessels, and quantified angiogenesis over time using a photon counting-based method. …”
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6559
Accessory Cavitated Uterine Mass with Associated Chocolate Cyst and Ureteric Endometrioma: A Case Report
Published 2025-06-01“…Accessory Cavitated Uterine Malformation (ACUM) is a Müllerian anomaly characterised by a non communicating uterine cavity lined with functional endometrium and surrounded by myometrium. …”
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6560
Optical Implementation of Butler Matrix for Hardware-Efficient Multiuser Beamforming
Published 2018-01-01“…With wireless systems migration toward simplified remote radio units through radio-over-fiber and sharing of signal processing functions located in the central office, it is desirable to implement this beamforming technique in the optical domain. …”
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