Multi-Omics analysis and in vitro validation reveal diagnostic and therapeutic roles of novel hub genes in ovarian cancer by Jianmin Wang, Guanghui Song, Lili Xing

“…In this study, we aimed to identify and functionally validate novel hub genes associated with OC progression. …”
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Novel Cross-Species Salivary Gland-Parasympathetic Neuron Coculture System by Hsueh- Wu, Mohamed Ishan, Md Rashid, Hong- Liu, Nadja Zeltner

“…The parasympathetic nervous system is essential for salivary gland development and functionality. Parasympathetic neuron (parasymN) innervation is the main neural network that controls salivary secretion. …”
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Quantitative evaluation of DNA damage repair dynamics to elucidate predictors of autism vs. cancer in individuals with germline PTEN variants. by Ruipeng Wei, Masahiro Hitomi, Tammy Sadler, Lamis Yehia, Daniela Calvetti, Jacob Scott, Charis Eng

“…The pleiotropy of the syndrome may, in part, be due to the alterations of the key multi-functions of PTEN. Maintenance of genome integrity is one of the key biological functions of PTEN, but no integrative studies have been conducted to quantify the DNA damage response (DDR) in individuals with PHTS and to relate to phenotypes and genotypes. …”
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LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis by Yihan Liu, Yuhua Wang, Long Cui, Runze Li, Dan Xiao, Dan Xiao

“…This study investigated the role of lncRNA OIP5-AS1 in lung adenocarcinoma (LUAD) progression and its involvement in macrophage polarization.MethodsThe expression of OIP5-AS1 in LUAD tissues and its association with patient prognosis were analyzed. Functional assays, including cell proliferation, migration, invasion, and cell cycle analysis, were conducted in LUAD cell lines. …”
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Heterologous expression of physic nut JcHDZ25 confers tolerance to drought stress in transgenic rice by Yuehui Tang, Xiaohui Wang, Yaoyao Wang, Jiatong Xie, Ruoyu Zhang, Tengfei Liu, Sainan Jia, Xinxin Bao

“…Although HD-Zip proteins are known regulators of stress responses, the functional roles of physic nut HD-Zip genes in drought adaptation remain uncharacterized. …”
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Dynamic clustering of genomics cohorts beyond race, ethnicity—and ancestry by Hussein Mohsen, Kim Blenman, Prashant S. Emani, Quaid Morris, Jian Carrot-Zhang, Lajos Pusztai

“…Results Results demonstrate clustering patterns that transcend discrete continent-based categories across cancer types. Functional analysis based on cancer type-specific clusterings also captures the fundamental biological processes underlying cancer, differentiates between dynamic clusters on a functional level, and identifies novel potential drivers overlooked by a predefined continent-based clustering. …”
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Heterogeneous protein dynamics links to mitochondrial activity, glucose transporter, and ALDH cancer stem cell properties by Martin Krkoška, Zuzana Tylichová, Pavlína Zatloukalová, Petr Müller, Bořivoj Vojtěšek, Philip John Coates

“…Various markers are used to identify CSCs, and have shown that different CSC subtypes may be present within a tumor. One functional property of CSCs is their relative lack of proteasomal activity compared to the tumor bulk. …”
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MiR-136 inhibits gastric cancer–specific peritoneal metastasis by targeting HOXC10 by Jianyong Zheng, Peng Ge, Xiaonan Liu, Jiangpeng Wei, Guosheng Wu, Xiaohua Li

“…Functions of microRNAs have been characterized in the embryologic, physiologic, and oncogenic processes, but the role of microRNAs in mediating tumor-specific organ metastasis was addressed only recently and still absent in gastric cancer peritoneal metastasis. …”
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Integration of single-cell and bulk RNA sequencing to identify a distinct tumor stem cells and construct a novel prognostic signature for evaluating prognosis and immunotherapy in... by Fengyun Zhao, Mengting Chen, Tianjiao Wu, Mingfang Ji, Fugui Li

“…It was over-expressed in LUAD cell lines and clinical tumor tissues, with high expression linked to poor prognosis. …”
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SNRPB2 facilitates esophageal squamous cell carcinoma oncogenesis and progression via E2F4 stabilization by Feng Xu, Chen-Cheng Zhu, Chen Lu, Guang-Yao Ning, Ren-Quan Zhang

“…Protein expression was assessed by immunohistochemistry in paraffin-embedded esophageal squamous cell carcinoma (ESCC) tissues. Functional assays in ESCC cell lines were conducted to determine the biological role of SNRPB2. …”
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Expression divergence of BAG gene family in maize under heat stress by Babar Farid, Muhammad Abu Bakar Saddique, Muhammad Hammad Nadeem Tahir, Rao Muhammad Ikram, Zulfiqar Ali, Waseem Akbar

“…This research offers a roadmap to plan functional research and utilize ZmBAG genes to enhance heat tolerance in grasses.…”
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Feasibility of an exergaming training program in type 2 diabetes mellitus: A mixed method study by Nikola Savic, Heidi Petry, Eling D. de Bruin, Roger Lehmann, Patrick Eggenberger, Manuela Adcock, Ruth Hirschmann, Ruud H. Knols

“…Secondarily, possible effects on physical, functional, and patient-reported outcomes were explored. …”
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For many but not for all: the bikini incision direct anterior approach for total hip arthroplasty. A narrative review by Cesare Faldini, Francesco Traina, Federico Pilla, Claudio D’Agostino, Matteo Brunello, Manuele Morandi Guaitoli, Alberto Di Martino

“…BI patients also experience better aesthetic outcomes and functional recovery, with reduced pain and itching. …”
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Modulation of Hypoxia-Inducible Factors and Vascular Endothelial Growth Factor Expressions by Superfood Camu-Camu (Myrciaria dubia) Treatment in ARPE-19 and Fetal Human RPE Cells by Ayaka Nakai, Deokho Lee, Chiho Shoda, Kazuno Negishi, Hiroyuki Nakashizuka, Satoru Yamagami, Toshihide Kurihara

“…The demand for disease prevention or treatment using functional foods such as superfoods has increased in recent years. …”
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MOVEMENTS OF ANATOMICAL COMPLEX: CONDYLAR PROCESS, TEMPOROMANDIBULAR JOINT, TEMPORAL BONE by R.S. Palyvoda, A.S. Volovar, A.V. Malikov

“… Based on the fundamental manuscripts and inventions, structure of organs depends on their functions. Each maxillo-facial surgeon should know basics of anatomic relationships of human body, especially maxilla-facial area. …”
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Icreasing the efficiency of district heating supply systems by local heat distribution station modernation by Yu. A. Gorinov, P. N. Anisimov

“…To consider the problems of functioning of an open heat supply system functioning. …”
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METHODICAL ASPECTS OF DEVELOPMENT OF MUSICAL-AUDITORY IMAGES OF PUPILS OF MUSIC SCHOOLS by Evgeniia B. Cherniak, Juliia V. Volskaya, Svetlana P. Mishchenko, Vladimir V. Yorkin

“…In historical and analytical research, images are considered as a complex phenomenon with the functioning of mnemonic, imaginative and spatial components. …”
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RETRACTED ARTICLE: Anticancer activity of lactoferrin-coated biosynthesized selenium nanoparticles for combating different human cancer cells via mediating apoptotic effects by Esmail M. El‑Fakharany, Marwa M. Abu‑Serie, Amany Ibrahim, Marwa Eltarahony

“…BLF is an ideal protein to be encapsulated or adsorbed into selenium nanocomposites (Se NPs) in order to produce stable nanocombinations with potent anticancer effects and improved immunological functions. The biosynthesis of the functionalized Se NPs was achieved using Rhodotorula sp. strain MZ312359 via a simultaneous bio-reduction approach to selenium sodium salts. …”
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Evaluation of 3D Nonlinear Earthquake Behaviour of the Ilısu CFR Dam under Far-Fault Ground Motions by Memduh Karalar, Murat Çavuşli

“…While defining these boundary conditions, the special fish functions are created and defined to the software. …”
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Zwilch kinetochore protein affects the prognosis of cancer patients by participating in cell proliferation, enhancing cell communication, and reshaping the tumor microenvironment by Long Yao, Lianpo Liu, Jinsong Wu, Yunlong Huang, Renquan Zhang, Haoxue Zhang

“…Combining multiple analytic approaches including GSEA, GSVA, KEGG enrichment analysis, and Aucell, with TCPA functional protein data, Genome-wide CRISPR screening, potential functions of ZWILCH and the pathways in which ZWILCH participated were thoroughly exploited. …”
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