Chromosome-level genome assembly of the Adonis ladybird Hippodamia variegata by Hong-Ling Liu, Yan-Ping Yong, Xing-Long Wu, Zhi-Teng Chen, Shu-Jun Wei, Peng Cai, De-Qiang Pu

“…Repetitive elements accounted for 258.56 Mb (52.44%) of the genome, with long interspersed nuclear elements (LINEs) being the most prevalent. We identified 37,348 protein-coding genes, of which 78.55% were functionally annotated in public protein databases. …”
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Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice by Anja Feldner, M Gordian Adam, Fabian Tetzlaff, Iris Moll, Dorde Komljenovic, Felix Sahm, Tobias Bäuerle, Hiroshi Ishikawa, Horst Schroten, Thomas Korff, Ilse Hofmann, Hartwig Wolburg, Andreas von Deimling, Andreas Fischer

“…LCAM1 and MPDZ (MUPP1) are the only known human gene loci associated with non‐syndromic hydrocephalus. To investigate functions of the tight junction‐associated protein Mpdz, we generated mouse models. …”
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THE RADIO WAVES PROPAGATION CHARACTERISTICS IN THE GLIDESLOPE AXES OF THE GROUND CONTROLLED APPROACH SYSTEMS IN THE ARCTIC REGIONS by G. S. Nakhmanson, D. V. Buchnev, A. V. Bunin

“…Calculated parameters of the probability density functions of these deviations at different distances from the runway for three Arctic regions of Russia. …”
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Blocked Autophagy by miR-101 Enhances Osteosarcoma Cell Chemosensitivity In Vitro by Zhiqiang Chang, Lifeng Huo, Kun Li, Yiming Wu, Zhenming Hu

“…Studies have shown paradoxical functions of autophagy in tumor development, which has been demonstrated by microRNAs. …”
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HTLV-I Basic Leucine Zipper Factor (sHBZ) Actively Associates with Nucleophosmin (B23) in the Nucleolus by Nahid Moghadam, Yong Xiao, Francois Dragon, Benoit Barbeau

“…Our previous study has shown that sHBZ colocalizes and associates with Nucleophosmin/B23, a nucleolar phosphoprotein with multiple functions. In this study, through an optimized nucleolar isolation method, we first confirmed sHBZ’s nucleolar localization via Western blotting in transfected HEK293T cells, chronically HTLV-1-infected T cell lines, and freshly infected HeLa cells. …”
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Microbial-transcriptome integrative analysis of heat stress effects on amino acid metabolism and lipid peroxidation in poultry jejunum by Young-Jun Seo, Chiwoong Lim, Byeonghwi Lim, Jun-Mo Kim

“…After the analysis, the host functional enrichment analysis revealed that pathways related to lipid and protein metabolism were elevated under heat stress conditions. …”
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Enhancements of G3-PLC Technology for Smart-Home/Building Applications by Luca Di Bert, Salvatore D'Alessandro, Andrea M. Tonello

“…Since Ethernet represents a convergent standard for many communication devices, by adding this functionality to G3-PLC, interconnectivity with other heterogeneous nodes can be offered. …”
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Analysis of Selected Methods of Computer-Aided Design for Stage Structures by Szymon Wyrąbkiewicz, Marcin Zastempowski, Jurand Burczyński, Maciej Gajewski

“…Collected data were organized in tables and displayed in line and column charts, based on which conclusions were drawn. …”
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High-Flow Nasal Cannula Therapy in a Patient with Reperfusion Pulmonary Edema following Percutaneous Transluminal Pulmonary Angioplasty by Kiyoshi Moriyama, Toru Satoh, Akira Motoyasu, Tomoki Kohyama, Mariko Kotani, Riichiro Kanai, Tadao Ando, Tomoko Yorozu

“…A 62-year-old woman with Wolff-Parkinson-White syndrome was with recent worsening of dyspnea to New York Heart Association functional status Class III. The patient was diagnosed as having central type chronic thromboembolic pulmonary hypertension. …”
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Natural Tooth Pontic: An Instant Esthetic Option for Periodontally Compromised Teeth—A Case Series by Rishi Raj, Kriti Mehrotra, Ipshita Narayan, Triveni Mavinakote Gowda, D. S. Mehta

“…Irrespective of the final treatment, the first line of management would be to provisionally restore the patient’s esthetic appearance at the earliest, while functionally stabilizing the compromised arch. …”
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LncRNA HSCHARME is altered in human cardiomyopathies and promotes stem cell-derived cardiomyogenesis via splicing regulation by Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Alessandro Palma, Angelo D’Angelo, Giulio Storari, Tiziana Santini, Pietro Laneve, Daniela Trisciuoglio, Monica Ballarino

“…In line with a possible association with disease, large-scale analysis of the lncRNA expression across cardiomyopathy patients reveals increased levels of pCHARME in hypertrophic and dilated hearts. …”
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Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe by Georgina D Barnabas, Tariq A Bhat, Verena Goebeler, Pascal Leclair, Nadine Azzam, Nicole Melong, Colleen Anderson, Alexis Gom, Seohee An, Enes K Ergin, Yaoqing Shen, Agustina Conrrero, Andrew J Mungall, Karen L Mungall, Christopher A Maxwell, Gregor S D Reid, Martin Hirst, Steven Jones, Jennifer A Chan, Donna L Senger, Jason N Berman, Seth J Parker, Jonathan W Bush, Caron Strahlendorf, Rebecca J Deyell, C James Lim, Philipp F Lange

“…By this, we show that proteome-guided and functional precision oncology are feasible and valuable complements to the current genome-driven precision oncology practices.…”
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Ion-Channel-Targeting Scorpion Recombinant Toxin as Novel Therapeutic Agent for Breast Cancer by Natalia Mata de los Rios, Argel Gastelum-Arellanez, Herlinda Clement, Karely Álvarez-Cruz, Diana Romero-Terrazas, Carolina Alvarado-González, Luis Carlos Hinojos-Gallardo, Gerardo Corzo, Gerardo Pável Espino-Solis

“…This study explores the potential therapeutic applications of bioactive fractions derived from <i>Chihuahuanus coahuilae</i>, in breast cancer cell lines. Through chromatographic separation, mass spectrometry, and functional assays, we assess their effects on cell viability, proliferation, and ion channel modulation. …”
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Tissue-resident immune cells in homeostasis and tissue repair by A. P. Toptygina

“…Most types of immune cells are able to freely enter tissues, perform surveillance functions, and then leave them, while distinct cells are permanently located in non-lymphoid tissues. …”
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Development of nanocomplex mimic‐hsa‐miR‐143‐3p loaded exosome (exo‐miR) to inhibit viability, migration and proliferation of triple‐negative breast cancer by Fita Nilasari, Sofia Mubarika Haryana, Dwi Aris Agung Nugrahaningsih, Pamungkas Bagus Satriyo

“…It is known that miR‐143‐3p functions as a tumor suppressor in breast cancer, and its overexpression corresponds with an increased survival rate. …”
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A comparative analysis of the effectiveness of tear substitutes for the treatment of dry eye syndrome by V. V. Dmitriev, I. A. Minenko, L. M. Balashova, T. Y. Shilova, T. V. Dmitrieva

“…The functional test indicators showed an improvement, too. …”
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Transcriptome and Metabolome Analysis of the Leaf Colour Mutation Mechanism in a Light-Green Leaf Mutant of Maize by Dan Li, Kuangzheng Qu, Dianrong Ma, Zhenxing Zhu, Xiaochun Lu

“…These processes are crucial for plant photosynthesis, respiration, and catalytic functions. This study not only provides a valuable resource for further investigation of plant photosynthetic systems but also establishes a foundational framework for the comprehensive functional characterisation of genes involved in the leaf colour change in the <i data-eusoft-scrollable-element="1">zmpgl</i> mutant. …”
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Integrative bulk RNA analysis unveils immune evasion mechanisms and predictive biomarkers of osimertinib resistance in non-small cell lung cancer by Ling Shi, Feng Qiu, Chao Shi, Guohua Zhang, Feng Yu

“…Functional enrichment analyses revealed critical pathways, including p53 signaling and metabolic reprogramming, underlying resistance mechanisms. …”
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Mixture of common and uncommon pathways and genes regulating primary and secondary immunoglobulin M responses in chickens by Somayeh Kianpoor, Alireza Ehsani, Rasoul Vaez Torshizi, Ali Akbar Masoudi, Mohammad Reza Bakhtiarizadeh

“…IgM acts as the first line of defense against new and invading infections. …”
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HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis by Xiaoying Wang, Huijun Liang, Qindan Du, Ying Li, Yong Zhao

“…Methods HACD3 expression was assessed in NSCLC tissues, cell lines, and GEPIA and HPA public databases. Functional consequences of HACD3 knockdown and overexpression were examined in vitro by assessing cell proliferation, colony formation, migration, cell cycle progression, and apoptosis, and in vivo through assays for xenograft tumorigenesis in NSG mice. …”
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