Integrated analysis and experimental validation reveal the prognostic and immunological features associated with coagulation in hepatocellular carcinoma by Guangzhen Qu, Kun Liu, Weiyu Xu, Dongming Li

“…Afterward, differential analyses of prognosis, biological processes, immune infiltration, and functional and pathway enrichment were conducted on the three CAG patterns. …”
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Suppression of pseudogene MT2P1 transcription induced by E2F7 inhibits hepatocellular carcinoma cell proliferation and facilitates apoptosis via preserving its parental gene by Yiquan Lu, Yifan Zhang, Fengjie Hao, Nan Wang, Yongjun Chen, Junqing Wang

“…Their transcripts are mostly attributed to non-coding RNAs that play various functions in human tumorigenicity and progression. …”
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A single incision transaxillary thoracoscopic sympathectomy by Marić Nebojša, Stanić Vojkan, Ristanović Aleksandar, Cvijanović Vlado, Milisavljević Slobodan

“…Single incision transaxillary thoracoscopic sympathectomy generates excellent aesthetic and functional results in patients with primary focal hyperhidrosis.…”
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Three-dimensional finite element analysis of occlusal stress on maxillary first molars with different marginal morphologies restored with occlusal veneers by Qing Chen, Siyang Luo, Yujuan Wang, Zhu Chen, Ying Li, Maohua Meng, Yamei Li, Nan Xiao, Qiang Dong

“…Three different edge designs were applied to identical teeth: straight-beveled finishing line(SFL), chamfer finishing line(CFL), and standard cuspal inclination(SCI). …”
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The polarity protein Par3 enhances renal cell carcinoma metastasis via YAP/TAZ activation by Soo Lee, Jonathan Balcazar, Karla Davis, Rey-Chen Pong, Jer-Tsong Hsieh, Payal Kapur, Xiaosong Meng

“…Interestingly, Par3’s functions vary among cancers: both Par3 elevation (in the prostate or liver) and loss (in the breast or lung) have been implicated in cancer metastasis. …”
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Scutellarin suppresses ovarian cancer progression by targeting METTL5 by Ling Ding, Cenxin Luo, Nathaniel Weygant, Wutao Chen, Dan Ru, Yi Lai, You Wang, He Li

“…The effects of Scutellarin on cell proliferation and migration were assessed in ovarian cancer cell lines including SKOV3, A2780, OVCAR3, and OVCAR8. …”
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PLEK2: a potential biomarker for metastasis and prognostic evaluation in uveal melanoma by Yichong Liu, Haiyue Wang, Qian Zhang, Xiaodi Gao, Yiqing Ji, Yuanzhang Zhu, Jingjing Zhang, Wenjuan Luo

“…PLEK2 expression in UVM cell lines was assessed using the CCLE database and confirmed by qPCR and western blot. …”
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Are we working (too) comfortably?: the systematic development of an intervention to support workers to move more while working at home by Divya Sivaramakrishnan, Claire Fitzsimons, Sarah Morton, Jillian Manner, Ruth Jepson, Ailsa Niven

“…In step 4, the intervention functions and behaviour change technique elements of the BCW were used to accurately and consistently specify the active ingredients of the intervention. …”
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Predictive Value of Optical Coherence Tomography Biomarkers in Patients with Persistent Diabetic Macular Edema Undergoing Cataract Surgery Combined with a Dexamethasone Intravitrea... by Giuseppe Fasolino, Maryam Lazaar, Domenico Giovanni Della Rocca, Silke Oellerich, Sorcha Ní Dhubhghaill

“…<b>Background:</b> Diabetic macular edema (DME) is the most common cause of vision loss among diabetic patients. The first-line treatments for DME are anti-vascular endothelial growth factor (VEGF)-drugs, while intravitreal steroids are generally reserved for second-line treatment. …”
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Comprehensive Pan-Cancer Analysis Reveals the Potential Biological, Immunological, and Prognostic Value of NKG2A by Yao Rong, Yongfeng Wang, Mingzheng Tang, Guiqian Zhang, Yuan Yuan, Fengyuan Dong, Zhihang Wu, Guorong Ma, Songhua Liu, Xiashuang Zhao, Hui Cai

“…Gene set enrichment analysis (GSEA) showed that NKG2A was associated with multiple immune-related functions and pathways in malignant tumors. qRT-PCR results showed that NKG2A was underexpressed in liver, gastric, and colon cancer cell lines compared to normal cells, which was consistent with bioinformatics analysis. …”
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Impact of Poly(Lactic Acid) and Graphene Oxide Nanocomposite on Cellular Viability and Proliferation by Karina Torres Pomini, Júlia Carolina Ferreira, Laira Mireli Dias da Silva, Paulo Gabriel Friedrich Totti, Monique Gonçalves Alves, Eliana de Souza Bastos Mazuqueli Pereira, Marcelo Melo Soares, Durvanei Augusto Maria, Rose Eli Grassi Rici

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Neoepitope BTLAP267L-specific TCR-T cell immunotherapy unlocks precision treatment for hepatocellular carcinoma by Fang Liu, Hua Chen, Suxin Wu, Chenlu Zhu, Mingji Zhang, Wei Rui, Dong Zhou, Yang Wang, Xin Lin, Xueqiang Zhao, Yunbin Ye

“…Patients with advanced HCC and T cell functional deficiencies may benefit more from cellular immunotherapy, especially tumor neoepitope-targeted T cell receptor (TCR)-T cells. …”
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miR-4537 curtails ferroptosis by targeting MIOX in renal cell carcinoma by Hui Li, Mengyu Fu, Lingli Wang, Yanpeng Dai, Zongxing Lv, Shilin Geng

“…Further investigations into MIOX regulation identified four miRNAs via TargetScan predictions, with miR-4537 significantly upregulated in ccRCC cell lines. Functional assays involving miR-4537 mimics and inhibitors, combined with ferroptosis inducers and inhibitors, elucidated its impact on ccRCC cell growth and ferroptosis modulation. …”
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Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma by Yan Zhao, Jenil Patel, Jinhua Fan, Xinyang Wang, Lin Chen, Yuanyuan Li, Zhengxiu Luo

“…The functional experiments of EGR1 were investigated in vitro via siRNA knockdown and over-expressed plasmid. …”
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Synthesis of Ethylphosphonate Curcumin Mimics: Substituents Allow Switching Between Cytotoxic and Cytoprotective Activities by Valeria Romanucci, Rita Pagano, Solveigh C. Koeberle, Andreas Koeberle, Minh Bui Hoang, Sonia Di Gaetano, Domenica Capasso, Michele Francesco Maria Sciacca, Valeria Lanza, Carmelo Tempra, Fabio Lolicato, Armando Zarrelli, Danilo Milardi, Giovanni Di Fabio

“…New EP mimics were synthesized by tyrosol- and melatonin-based building blocks using an orthogonal protection approach of the different precursors’ OH functions with good yields and in a few steps. Comparative screenings of the cytotoxic and cytoprotective properties (curcumin was used as a reference compound) were carried out on all new mimics in different cell lines (HeLa, A375, WM266, MDA-MB-231, LX2, and HDF). …”
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Pan-Genome Analysis of <i>TRM</i> Gene Family and Their Expression Pattern under Abiotic and Biotic Stresses in Cucumber by Lili Zhao, Ke Wang, Zimo Wang, Shunpeng Chu, Chunhua Chen, Lina Wang, Zhonghai Ren

“…Collectively, this study provided a base for the further functional identification of <i>CsTRM</i> genes in cucumber plant growth and stress resistance.…”
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Enhanced expression of ten‐eleven translocation 1 reverses gemcitabine resistance in cholangiocarcinoma accompanied by a reduction in P‐glycoprotein expression by Chuanxu Wang, Hua Ye, Lei Zhang, Yayu Cheng, Shifeng Xu, Ping Zhang, Zijie Zhang, Jimin Bai, Fangkang Meng, Lin Zhong, Guangjun Shi, Hao Li

“…Abstract Increasing evidence revealed that ten‐eleven translocation 1 (TET1) plays an important role in tumorigenesis and chemoresistance, but its functions in gemcitabine resistance in cholangiocarcinoma (CCA) remain unknown. …”
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SLNP-based CDK4- targeted nanotherapy against glioblastoma by Uzma Ghani, Fareeha Khalid Ghori, Muhammad Usman Qamar, Muhammad Usman Qamar, Hina Khan, Basit Azad, Sabahat Habib, Saira Justin, Ishaq N. Khan, Ishaq N. Khan, Tawaf Ali Shah, Gamal A. Shazly, Mohammed Bourhia, Fouzia Perveen, Aneela Javed

“…Sil showed decreased cell viability 72 h after treatment against both U87 and U251 cell lines but had negligible cytotoxic effect on HEK-293. …”
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Effect of arm-ergometry versus treadmill supervised exercise on health-related quality of life and mental health in patients with peripheral artery disease: secondary outcomes from... by Sandra Magalhães, Mário Santos, Sofia Viamonte, Fernando Ribeiro, Joana Martins, Cristine Schmidt, Henrique Cyrne-Carvalho

“…In the TEx group, physical functioning, role-physical, bodily-pain, vitality, social functioning, role-emotional and PCS significantly improved. …”
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Exploring the prognostic role and expression patterns of FAM3A family genes in kidney renal clear cell carcinoma by Shoaib Muhammad, Pengyu Yan, Huifang Wang, Ahmad Mahmood, Syed Shah Zaman Haider Naqvi, Muhammad Zaeem, Chun Liu

“…This study investigated the expression, diagnostic potential, and functional significance of FAM3 family genes in KIRC. …”
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