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Identification of DCAF5 as a novel cancer prognostic and immunotherapy biomarker through pan-cancer analysis and renal clear cell carcinoma clinical data validation
Published 2025-06-01“…This highlights its potential as a dual-functional biomarker for prognosis and immunotherapy personalization, particularly in SMARCB1-deficient malignancies.…”
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1762
Advanced smart assistance with enhancing social interaction and daily activities for visually impaired individuals using deep learning with modified seagull optimization
Published 2025-05-01“…The ADD-MSGOEL method is designed to enhance the social life and daily functioning of visually impaired people by accurately detecting damage and potential hazards in their surroundings. …”
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1763
Analysis of medication rule of Traditional Chinese Medicine in treating depression based on data mining
Published 2024-10-01“…As a highly prevalent disorder, it seriously endangers the psychosocial functioning of patients. Many scholars have conducted clinical studies on the treatment of depression using different herbal remedies, but there are no studies that integrate these remedies to explore the general medication rule. …”
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1764
Genome-wide identification and analysis of the FLA gene family in maize (Zea mays L.) and its expression in response to abiotic stresses
Published 2025-07-01“…However, these proteins have not yet been identified or characterized in maize. This study conducted bioinformatics and expression analyses of the ZmFLA gene family. …”
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Evaluation of different erosion models for predicting guide vane wear in Francis turbine
Published 2025-02-01“…This study has been conducted to determine which of the erosion model predicts the erosion pattern closer to the real case of eroded GV of Jhimruk Hydro-Electric Plant (HEP). …”
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1767
Dissecting biological heterogeneity in major depressive disorder based on neuroimaging subtypes with multi-omics data
Published 2025-03-01“…The amplitude of low-frequency fluctuations (ALFF), a functional neuroimaging feature, was extracted for each participant and used to identify MDD subtypes through machine learning clustering. …”
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1768
miR-34-5p mediates 20E-induced autophagy in the fat body of Bombyx mori by targeting Atg1
Published 2025-03-01“…Results We constructed six small RNA libraries using Bombyx mori fat body treated with 20E. Expression and functional analyses were conducted to identify 20E-responsive miRNAs. …”
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1769
Identification and expression analysis of P-type ATPase IIIA subfamily in Puccinia Striiformis f. sp. tritici
Published 2025-01-01“…To investigate the potential functions of the PMA gene family in Pst, we conducted a genome-wide bioinformatics analysis and examined the expression profiles of the PMA gene family. …”
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Results of Quantitative and Qualitative Assessment of Color Vision in Patients with Congenital Partial Atrophy of the Optic Nerve
Published 2024-04-01“…Congenital partial atrophy of the optic nerve is one of the main causes of blindness and low vision in patients with fundus pathology, and the study of color vision is important in diagnosis and monitoring visual functions in patients with this disease.Purpose: to study the possibilities of using the own developed method of quantitative and qualitative assessment of color vision in patients with partial optic nerve atrophy.Materials and methods. 55 patients aged from 8 to 20 years with congenital partial atrophy of the optic nerve (PAON) with a typical fundus pattern and EFI indicators for this disease were observed. …”
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Pathophysiological mechanisms in severe preeclampsia: role of upregulated proteins in blood pressure, extracellular matrix and immunity
Published 2025-08-01“…Protein identification and annotation were performed using UniProt and PatternLab for Proteomics. Multivariate statistical analyses, including PLS-DA and sPLS-DA, as well as VIP score evaluation and Volcano plot visualization, were conducted with MetaboAnalyst to assess group separation and identify key discriminative features. …”
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1772
Fine-scale variability in iceberg velocity fields and implications for an ice-associated pinniped
Published 2025-06-01“…Environmental forcings can drive dramatic changes in the overall reduction in ice coverage across fjords in the circumpolar regions, with implications for pinnipeds that use ice for critical life-history functions, including pupping and molting. To better understand how pinnipeds respond to changes in iceberg habitat, we combine (i) iceberg velocity fields over hourly to monthly timescales, derived from high-rate time-lapse photogrammetry of Johns Hopkins Glacier and Inlet, Alaska, with (ii) aerial photographic surveys of harbor seals (<i>Phoca vitulina richardii</i>) conducted during the pupping (June) and molting (August) seasons. …”
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1773
Simulation Analysis of Water Resource Scheduling in Nansu River Based on Coupled Water Quality-Quantity Model
Published 2025-06-01“…[Objectives] With the socioeconomic development, conflicts among the population, water resources, and the environment have become increasingly prominent. Conducting research on water quality and quantity in rivers that flow through urban areas and serve functions such as water supply and irrigation, and implementing rational scheduling, is of significance for ensuring a healthy aquatic ecosystem and enhancing the well-being of local residents. …”
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1774
CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway
Published 2024-12-01“…Cell counting kit-8 (CCK-8) assay, colony formation assay, flow cytometry, wound healing assay, and Transwell assay were conducted for in vitro functional experiments. In vivo experiments involved subcutaneous tumor formation in nude mice. …”
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Synthesis and Evaluation of the Antibacterial and Antioxidant Activities of Some Novel Chloroquinoline Analogs
Published 2021-01-01“…The molecular docking study of the synthesized compounds was conducted to investigate their binding pattern with topoisomerase IIβ and E. coli DNA gyrase B. …”
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Association between Serum 25-Hydroxyvitamin D and Abdominal Aortic Calcification: A Large Cross-Sectional Study
Published 2023-01-01“…Finally, a subgroup analysis was conducted. There were a total of 3,040 individuals in our study. …”
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Green Infrastructure Network Planning in Urban Fringe Areas Based on the Characteristics of Agricultural and Forestry Landscape Ecological Network in a Metropolitan City
Published 2025-03-01“…Small-scale, dispersed agroforestry spaces in the urban fringe constitute ecological land that serves dual public benefit functions: natural ecological conservation and rural-urban services. …”
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TWO DECADES OF ARCHAEOLOGICAL RESEARCH IN THE SOUTHERN DISTRICT OF THE CITY OF TROPAEUM TRAIANI (4th-6th CENTURIES AD.) AND OTHER DISCOVERIES. MAJOR SCIENTIFIC RESULTS
Published 2025-08-01“…Archaeological researches from the last decade, conducted in the southern neighborhood of the late Roman city Tropaeum Traiani, revealed a new civil imposing edifice, having a rectangular and axial plan, which corresponds to the „pattern” of the big Roman house, Domus type. …”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov...
Published 2025-07-01“…The same applied for PBMC mitochondrial functionality and metabolic activity as assessed by ex vivo approaches, whereas non-mitochondrial respiration rate was significantly affected by L-carnitine supplementation over time. …”
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Effects of Potassium Supply in Nutrient Solution on Water and Nutrient Absorption of Substrate-Grown Tomato Plants
Published 2025-06-01“…Potassium (K<sup>+</sup>) functions as a critical “regulator” and “quality element” in plants, with its physiological roles varying across developmental stages. …”
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