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1621
Assessing the causal effect of inflammation‐related genes on myocarditis: A Mendelian randomization study
Published 2025-02-01“…The results of PPI analysis showed that 20 genes were predicted to be associated with IRF7 function, such as response to type I interferon, pattern recognition receptor signalling pathway, and toll‐like receptor signalling pathway. …”
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1622
Longitudinal characterization of the muscle metabolome in dairy cows during the transition from lactation cessation to lactation resumption
Published 2025-01-01“…The targeted metabolomics approach was conducted using the MxP Quant 500 kit (Biocrates Life Sciences AG) with liquid chromatography, flow injection, and electrospray ionization triple quadrupole mass spectrometry. …”
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1623
Raman spectroscopy and bioinformatics-based identification of key genes and pathways capable of distinguishing between diffuse large B cell lymphoma and chronic lymphocytic leukemi...
Published 2025-02-01“…In this study, bioinformatics analyses of these two NHL subtypes were conducted, identifying key patterns of gene expression and then experimentally validating the results. …”
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1624
Patients with chronic hepatitis B under nucleos(t)ide analog therapy with Omicron BA.5 infection: A retrospective study in South China
Published 2025-03-01“…Methods: This retrospective study was conducted from January to March 2023 in a cohort of 485 healthy individuals and 553 patients with CHB. …”
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1625
Effector Pt31812 from Puccinia triticina acts as avirulence factor for Lr42-mediated resistance in wheat
Published 2025-07-01“…Subcellular localization of Pt31812 was analyzed using transient expression on Nicotiana Benthamiana. Further functional analysis was conducted using transient expression and host-induced gene silencing (HIGS). …”
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1626
Hemoglobin-associated CALR in proximal tubule cells can be used as a biomarker for idiopathic membranous nephropathy
Published 2025-06-01“…Functionally, CALR plays crucial roles in both immune response (particularly in antigen presentation) and physiological processes (notably in hemoglobin production).…”
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1627
Interplay of a non-conjugative integrative element and a conjugative plasmid in the spread of antibiotic resistance via suicidal plasmid transfer from an aquaculture Vibrio isolate...
Published 2018-01-01“…Tn6283 is unusual among integrative elements in that it apparently does not encode transfer function and its excision barely generates unoccupied donor sites. …”
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1628
TASTY trial: protocol for a study on the triad of nutrition, intestinal microbiota and rheumatoid arthritis
Published 2025-04-01“…It has been proposed that gut dysbiosis impairs gut barrier function, leading to alterations in mucosal integrity and immunity. …”
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1629
Assessment and Optimization of Hydrological Connectivity for Effective Management of Water Resources in the Samian Watershed
Published 2024-09-01“…To protect these water zones from destruction and disappearance and improve the overall ecological function of the water system, they had to be integrated into the hydrological connection pattern. …”
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1630
Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract
Published 2025-01-01“…Histopathologic review was conducted by independent pathologists. Relapse event was the time‐to‐event outcome, and relapse probabilities were estimated using a competing risk method with cumulative incidence functions (CIFs). …”
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1631
The impact of phthalates on asthma and chronic obstructive pulmonary disease: a comprehensive analysis based on network toxicology and molecular docking
Published 2025-03-01“…By integrating information from multiple databases, we identified key target genes linked to these compounds and conducted functional enrichment analyses to elucidate their roles in pathological processes.ResultsOur results demonstrate that these phthalates affect the pathogenesis of asthma and COPD by modulating various target genes, including PTGS2, MMP9, and CASP3, which are involved in essential biological pathways such as apoptosis and immune response. …”
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1632
Tp40: a new potential prognostic and diagnostic marker for syphilis
Published 2025-03-01“…Besides, based on experiments with animal models and the detection of human serum samples, we believe that the Tp40 protein is a potential in vivo-induced antigen of T. pallidum that can be used for serological diagnosis of syphilis. This study conducted a preliminary exploration of the Tp40 protein and provided a meaningful reference for further exploration of the functional mechanism of the Tp40 protein and its significance in clinical diagnosis.…”
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1633
Requirements for Becoming a Startup: A Study with an Economic Sociology Approach (Case Study: Managers of Startups in Isfahan City)
Published 2025-09-01“…Data collection was conducted via semi-structured in-depth interviews from early April to late November 2024. …”
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1634
Phasic and periodic change of drought under greenhouse effect
Published 2024-10-01“…Two abrupt changes in the drought pattern were observed during the study period, namely, in 1965 and 1983. …”
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1635
Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer
Published 2025-07-01“…Mouse model was constructed for in vivo validation of KAT2B and TAF1L function. Results In our study, we utilized the TCGA-BRCA database to conduct a comprehensive analysis of the acetylation regulatory pattern in luminal breast cancer. …”
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1636
Genetic Parameters, Linear Associations, and Genome-Wide Association Study for Endotoxin-Induced Cortisol Response in <i>Holstein heifers</i>
Published 2025-06-01“…Lipopolysaccharide (LPS) endotoxin is a well-characterized microbe-associated molecular pattern (MAMP) that forms the outer membrane of both pathogenic and commensal Gram-negative bacteria. …”
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1637
A Study on the Possibility of Molecular Communication between Honey Bees and Sunflower through the Interspecies Transfer of Small RNAs
Published 2024-12-01“…Limited studies have been conducted on the role of dietary miRNAs in honeybees, which are critical pollinators in agricultural industries and natural ecosystems. …”
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1638
Identification and expression analysis of ACBPs family members of Hippophae rhamnoides subsp. sinensis Rousi in response to lead stress
Published 2025-03-01“…Multiple sequence alignment and gene structure analyses were conducted using MEGA software and the GSDS website. …”
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1639
Geochemical and hydrocarbon generation evolution characteristics of marine-continental transitional facies shale: a case study of the Lower Permian Shanxi Formation in the Daning-J...
Published 2025-07-01“…For C1-5, the two peaks of activation energy were 56 kcal/mol (28.45%) and 61 kcal/mol (19.18%), with a frequency factor of 2.2×1011 S-1. (4) The variation trend between cumulative gas production rate and Ro for the marine-continental transitional facies shale in the Shanxi Formation followed the pattern of a logistic function described by y=1/(1+e-x). …”
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1640
The Elephant Ethogram: a library of African elephant behaviour
Published 2021-11-01“…The Elephant Ethogram combines and significantly improves the structure and functionality of the original databases, includes hundreds of additional behaviours, 2,400 annotated video clip examples from three populations, higher-resolution images, additional audio files. …”
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