Development and Validation of a Brain Aging Biomarker in Middle-Aged and Older Adults: Deep Learning Approach by Zihan Li, Jun Li, Jiahui Li, Mengying Wang, Andi Xu, Yushu Huang, Qi Yu, Lingzhi Zhang, Yingjun Li, Zilin Li, Xifeng Wu, Jiajun Bu, Wenyuan Li

“…Brain age gap exhibited clinical feasibility combined with Functional Activities Questionnaire, with improved discriminative capacity in models achieving lower MAEs (AUC of 0.945 vs 0.923 and 0.911; AUC of 0.935 vs 0.900 and 0.881). …”
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Structural Brain Changes in Patients with Congenital Anosmia: MRI-Based Analysis of Gray- and White-Matter Volumes by Shun-Hung Lin, Hsian-Min Chen, Rong-San Jiang

“…A separate analysis of the left and right hemispheres revealed similar patterns of reduced GM and increased WM volumes in patients with CA across both sides. …”
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FNDC5 and ACOX1 as Biomarkers of Peroxisomal Activity with Contrast Outcomes in Colon Adenocarcinoma by Yuan Hepei, Zeng Jun, Khan Muhammad, Wang Baiyao, Hu Xiaoshan, Wei Hao, Wang Zhaotong, Yuan Yawei

“…The high-risk group was linked to advanced stage, higher MSI, CMS4 subtype enrichment, distinct mutation patterns, and increased genome integrity pathway mutations (79% vs. 66%). …”
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Three different methods for ZnO-RGO nanocomposite synthesis and its adsorption capacity for methylene blue dye removal in a comparative study by Safaa A. Hussein, Gharib M. Taha, F. A. Adam, Marwa A. Moghazy

“…FTIR analysis approves that combining ZnO with RGO affects the functional groups of the three nanocomposite surfaces. …”
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Characterizing Patient-Reported Fatigue Using Electronic Diaries in Neurodegenerative and Immune-Mediated Inflammatory Diseases: Observational Study by Adrien Bennetot, Rana Zia Ur Rehman, Robbin Romijnders, Zhi Li, Victoria Macrae, Kristen Davies, Wan-Fai Ng, Walter Maetzler, Jennifer Kudelka, Hanna Hildesheim, Kirsten Emmert, Emma Paulides, C Janneke van der Woude, Ralf Reilmann, Svenja Aufenberg, Meenakshi Chatterjee, Nikolay V Manyakov, Clémence Pinaud, Stefan Avey

“…ObjectiveThis study aimed to evaluate the feasibility and acceptability of using a high-frequency eDiary to capture intraday variability in fatigue and to compare eDiary data with scores obtained from the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), a validated weekly recall PRO. …”
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Genome-wide identification and characterisation of Toll-like receptors in Chinese spiny frog (Quasipaa spinosa) by Zehong Li, Zihan Gao, Dexin Mo, Zifeng Zhu, Jingqi Zhang, Mujin Liu, Han Xiao, Meng Zhou, Teng Gao, Rishen Liang

“…IntroductionToll-like receptors (TLRs) are pattern recognition receptors essential for immune defense against pathogens, activating the host’s immune response by recognizing conserved pathogen structures. …”
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Uncovering Subclinical Cardiac Involvement in VEDOSS: An Echocardiographic Driven Study by Eugenio Capparelli, Eleonora Zaccara, Ilaria Suardi, Antonella Laria, Laura Castelnovo, Eleonora Mauric, Daniela Bompane, Antonio Tamburello, Maria Iacovantuono, Maria Sole Chimenti, Antonino Mazzone, Paola Faggioli

“…<b>Conclusions:</b> Careful monitoring of cardiac function in VEDOSS patients is crucial as subclinical alterations may occur even in the absence of symptoms. …”
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Canopy‐Mediated Dynamics of Moss Communities in Primary Succession: Coupling of N2‐Fixation and Biomass Accumulation in Subalpine Forests Following Glacial Retreat by Jie Deng, Genxu Wang, Shouqin Sun, Wentian Xie, Feng Long, Zhaoyong Hu, Juying Sun, Xiangyang Sun, Thomas H. DeLuca

“…The effects of canopy cover and composition on moss productivity, photosynthesis, and N2‐fixation rates represent a dynamic set of canopy‐bottom layer interactions that may shape the structure and function of developing subalpine forest.…”
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Long Noncoding RNA GATA3-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Suppression of PTEN, CDKN1A, and TP53 by Xuee Luo, Ning Zhou, Le Wang, Qinghua Zeng, Hongying Tang

“…However, the expression pattern and function of GATA3-AS1 in hepatocellular carcinoma (HCC) remain unknown. …”
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Efficacy and safety of diacerein in patients with knee osteoarthritis by L. I. Alekseeva, N. G. Kashevarova, E. A. Taskina, E. P. Sharapova, S. G. Anikin, T. A. Korotkova, E. A. Strebkova

“…Pain did not increase after the drug was discontinued (the follow-up period was 3 months). The same pattern was observed in the assessment of the WOMAC index (pain during early therapy, 243.8±73.9; pain at the end of therapy, 137.5±78.9; stiffness, 97.8±41.1 and 57.7±38.6; functional failure, 875.8±250.4 and 525±305.7 respectively; p&lt;0.0001). …”
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Re-composing Physical Form with Energy-Based Resilience Approach to Improve Thermal Comfort (Case Study: Sadra New Town) by Sahar Akbari, Mahsa Sholeh, Sahand Lotfi

“…In the first step, energy resilience criteria based on global energy resilience rating systems and theoretical research conducted, including smart location, resources and energy, transportation and use, neighborhood form and development pattern, and placemaking, were identified as five layers. …”
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Wogonin inhibits the proliferation of prolactinoma through the PI3K/AKT signaling pathway by Zhiyong Du, Zhiyong Du, Zhiyong Du, Zhiyong Du, Cuiping Sun, Cuiping Sun, Cuiping Sun, Cuiping Sun, Jiawei Wu, Jiawei Wu, Hongwei Gao, Hongwei Gao, Hongwei Gao, Hongwei Gao, Jialong Wu, Jialong Wu, Jialong Wu, Jialong Wu, You Zhou, You Zhou, You Zhou, You Zhou, Xuechao Wu, Xuechao Wu, Liping Shen, Liping Shen, Qing Wang, Qing Wang, Qing Wang, Qing Wang

“…Functional and pathway enrichment analyses were executed utilizing Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) methodologies. …”
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Construction of Ancestral Chromosomes in Gymnosperms and the Application in Comparative Genomic Analysis by Haoran Liao, Lianghui Zhong, Yujie He, Jie He, Yuhan Wu, Ying Guo, Lina Mei, Guibing Wang, Fuliang Cao, Fangfang Fu, Liangjiao Xue

“…Chromosome rearrangements during plant evolution can lead to alterations in genome structure and gene function, thereby influencing species adaptation and evolutionary processes. …”
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Therapeutic Effects of Forest Bathing on Human Health: A Systematic Review by Adrianna Samoraj, Jakub Zajączkowski, Paulina Krzeszowska, Kacper Stępniak, Karolina Marrodán-Wojtczak, Jan Wilk, Jakub Jarmołowicz, Aleksandra Kujawa, Karolina Krochmal, Radosław Kuźma

“…Materials and Methods: A systematic search of the PubMed database was conducted to extract relevant articles published between 1975 and 2023. …”
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Construction of cartilaginous organoids based on cartilage extracellular matrix microcarriers to promote articular cartilage regeneration through immune regulation by Hongyu Jiang, Wei Liu, Jiajie Chen, Yue Tian, Zhibo Jia, Yanbin Wu, Yanjun Guan, Leijia Chen, Wenjing Xu, Haoye Meng, Yingjie Xiong, Jianting Ye, Cheng Huang, Ruichao He, Sice Wang, Yufei Ding, Wei Fan, Yunkang Yang, Jiang Peng, Aiyuan Wang

“…The evaluation of their biological function was conducted through live/dead staining, CCK-8 assay, scratch assay, and Transwell assay in a laboratory setting. …”
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Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms by Jing Mao, Jianping Lan, Zheyu Zhuang, Ying Chen, Ying Chen, Yushan Ou, Xinhong Su, Xueting Zeng, Fuchen Huang, Zequn Tong, Xiaoqing Lv, Xiaoqing Lv, Xiaoqing Lv, Hui Ke, Zhenlan Wu, Ying Zou, Bo Cheng, Bo Cheng, Bo Cheng, Chao Ji, Chao Ji, Chao Ji, Ting Gong

“…This study aims to investigate the expression patterns and potential biological functions of ferroptosis-related genes in pemphigus, as well as their regulatory mechanisms.MethodsTo achieve this, skin samples from five pemphigus patients and five healthy controls were collected from Fujian Medical University Union Hospital. …”
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Impact of Climate and Soil on Plant Dynamics and Ecosystem Stability in Argan Orchards by Maryem Telmoudi, Chaima Afi, Naima Chabbi, Said Labbassi, Assma Oumasst, Mohamed Ouknin, Rachid Bouharroud, Abdelaziz Mimouni, Mimoun El Kaoua, Driss Hsissou, Abdelghani Tahiri, Naima Ait Aabd

“…We utilized alpha diversity indices (Shannon, Simpson, Pielou’s, and Margalef’s) and beta diversity indices (Jaccard and Sorenson Similarity) to examine these patterns. Seasonal changes were predominantly influenced by temperature and precipitation, while diverse soil types shaped by relief, climate, and water balance contributed to different ecological functions. …”
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Reproductive performance and fertility traits in Madrasin cattle: The influence of growth differentiation factor-9 gene expression on reproductive tract size, cervical mucus charac... by Budi Utomo, Rimayanti Rimayanti, Rochmah Kurnijasanti, Nurhusien Yimer Degu, Athhar Manabi Diansyah, Muhammad Fajar Amrullah

“…Background and Aim: The growth differentiation factor-9 (GDF-9) gene is recognized as a critical regulator of ovarian function and fertility in cattle. However, its role in crossbred populations, particularly Madrasin cattle (Madura × Simmental cross), remains underexplored. …”
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Prediction of Pulmonary Hypertension in Patients with Diffuse Parenchymal Lung Disease using Forced Vital Capacity/ Diffusion Capacity of Lung using Carbon Monoxide Ratio: A Cross-... by Anubhab Moulik, Jaydip Deb, Sourindra Nath Banerjee, Priyanka Ray, Pulak Kumar Jana, Sukanta Kodali, Saswata Ghosh

“…The initial diagnostic work-up includes Pulmonary Function Tests (PFT), such as spirometry and diffusion tests. …”
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A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival by Andrea FERENCZI, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“…METHODS – A cross-sectional, quantitative survey was conducted with 809 participants (626 women and 183 men; M_age = 40.8 years, SD = 13.85). …”
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