Tracking Lava Flow Cooling from Space: Implications for Erupted Volume Estimation and Cooling Mechanisms by Simone Aveni, Gaetana Ganci, Andrew J. L. Harris, Diego Coppola

“…Beyond volume estimation, we show that VRP_TIR cooling curves follow a consistent decay pattern that aligns with established theoretical thermal models, indicating a stable conductive regime during the cooling stage. …”
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Heritability and Genetics of Type 2 Diabetes Mellitus in Sub-Saharan Africa: A Systematic Review and Meta-Analysis by Evans Adu Asamoah, Christian Obirikorang, Emmanuel Acheampong, Max Efui Annani-Akollor, Edwin Ferguson Laing, Eddie-Williams Owiredu, Enoch Odame Anto

“…Results. The pattern and characteristics of T2DM heritability in SSA are preference for maternal aggregation, higher among first degree compared to second-degree relatives; early age-onset (<50 years), and inherited abnormalities of beta-cell function/mass. …”
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Microvascular heterogeneity exploration in core and invasive zones of orthotopic rat glioblastoma via ultrasound localization microscopy by Xing Hu, Gaobo Zhang, Yong Wang, Xiandi Zhang, Rong Xie, Xin Liu, Hong Ding

“…Capillary pattern, capillary hemodynamics, and functional quantitative parameters were compared among tumor core, invasive zone, and normal brain tissue with ex vivo micro-computed tomography (micro-CT) and scanning electron microscopy. …”
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ZmNF-YB10, a maize NF-Y transcription factor, positively regulates drought and salt stress response in Arabidopsis thaliana by Yimeng Wang, Peng Jiao, Chenyang Wu, Chunlai Wang, Ke Shi, Xiaoqi Gao, Shuyan Guan, Yiyong Ma

“…In yeast cells, ZmNF-YB10 exhibited a biological function that enhances salt and drought tolerance. …”
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PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

“…Although phosphatase and tensin homolog (PTEN) have been recognized as a potential tumor suppressor in all kinds of cancers, its function in RCC remains to be thoroughly elucidated. …”
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Enhancing corrosion resistance of Al alloy sheets with potential gradient by arc-sprayed Zn coatings by Zhipeng Yuan, Yuanlong Jiang, Yifan Lu, Keyuan Zhang, Huanjian Xie, Zenglei Ni, Liang Huang, Jia Liu, Xingxing Wang, Jin Peng, Zicheng Ling, Jianjun Shi, Peng He

“…Electrochemical testing was conducted on the surface of Al alloy sprayed with Zn layers at different depths. …”
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Expression Analysis and SNP Mining of the Parkin Co-Regulated Gene (PACRG) and parkin in Penaeus vannamei Against White Spot Syndrome Virus by Qian XUE, Xupeng LI, Yang LI, Sheng LUAN, Kun LUO, Jie KONG, Qun XING, Xianhong MENG

“…Post-WSSV infection, PACRG and parkin exhibited similar expression patterns in the eyestalk. The location of PACRG mRNAs mostly overlapped with the WSSV replication site in the shrimp muscle, suggesting that PACRG plays a functional role in the interaction between P. vannamei and WSSV. …”
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Identification and Expression Analysis of the Phospholipase D Gene Family in Rice by Huasheng CAO, Tang LI, Liang XIONG, Fujun WANG, Shuguang LI, Haiyong GU, Gao HE, Shihu LIANG, Wenyong LUO

“…【Objective】Phospholipase D (PLD) plays a crucial role in plant growth, development, and stress response. The study was conducted to explore the PLD gene family members involved in biotic and abiotic stress in rice (Oryza sativa L.) and investigate their biological functions.…”
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Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…<b>Methods</b>: This systematic review conducted in line with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines synthesizes the current evidence, identifies patterns, and highlights areas needing further research, offering a cohesive understanding of the topic. …”
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Multiomics integration analysis identifies tumor cell-derived MIF as a therapeutic target and potentiates anti-PD-1 therapy in osteosarcoma by Yan Liao, Hao Yao, Weidong Chen, Yutong Zou, Ji Fang, Jiongfeng Zhang, Zehao Guo, Jian Tu, Junkai Chen, Zijun Huo, Lili Wen, Xianbiao Xie

“…In vitro coculture functional assays were performed to validate the role of macrophage migration inhibitory factor (MIF) in macrophage polarization and chemotaxis. …”
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Phenome-wide association studies between SERINC2 and neuropsychiatric disorders by Ping Liu, Xinqun Luo, Liping Cao, Yong Zhang, Jiawu Ji, Xiaoping Wang, Kesheng Wang, Xinghua Pan, Ruilan Yang, Zewen Tan, Yunlong Tan, Chiang-shan Li, Xiaoyun Guo, Zhiren Wang, Xingguang Luo, Xingguang Luo

“…SNP-disease associations were tested and then meta-analyzed, followed by FDR correction, to identify significant disease-risk SNPs. Finally, functional studies on the differential SERINC2 mRNA expression in brains and the potential regulatory effects of disease-risk alleles on SERINC2 mRNA expression, gray matter volumes (GMVs) of subcortical structures, cortical surface area (SA) and average thickness (TH) were conducted.ResultsIn European descent, alcoholism was most significantly associated with SERINC2 variants (245 SNPs with 5.5×10-8≤p ≤ 0.049 and 4.9×10-5≤q ≤ 0.034) that were largely shared across cocaine dependence, marijuana dependence, nicotine dependence, polysubstance dependence, schizophrenia, OCD, and autism (8.2×10-8≤p ≤ 0.050 and 1.9×10-5≤q ≤ 0.049); in Chinese population, bipolar disorder was also significantly associated with SERINC2 variants (10 SNPs: 1.3×10-4≤p ≤ 4.7×10-4 and 0.025≤q ≤ 0.031). …”
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Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration by Christabel Thembela Dube, Hamish T. J. Gilbert, Niamh Rabbitte, Pauline Baird, Sonal Patel, Jeremy A. Herrera, Ivona Baricevic-Jones, Richard D. Unwin, Danny Chan, Kanna Gnanalingham, Judith A. Hoyland, Stephen M. Richardson

“…Given that systemic plasma changes are complex, a larger sample cohort may be required to identify patterns in blood relating to IVD degeneration progression. …”
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Integrin beta‐like 1 is regulated by DNA methylation and increased in heart failure patients by Lauren Kerrigan, Kevin Edgar, Adam Russell‐Hallinan, Oisin Cappa, Nadezhda Glezeva, Carlos Galan‐Arriola, Eduardo Oliver, Borja Ibanez, John Baugh, Patrick Collier, Mark Ledwidge, Ken McDonald, David Simpson, Sudipto Das, David J. Grieve, Chris J. Watson

“…Subsequent in vitro analyses were conducted to elucidate a role for ITGBL1 in human cardiac fibroblasts. …”
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Genome-wide identification and gene expression analysis of the malate dehydrogenase (MDH) gene family in Eucalyptus grandis by Yifan Xing, Yifan Xing, Huiming Xu, Deming Yang, Lichuan Deng, Guolong Li, Guolong Li, Zhixin Zhao, Zhixin Zhao, Zhaohua Lu, Liuyin Ma, Guangyou Li

“…Malate dehydrogenases are pivotal in plant metabolism and stress responses, yet their evolutionary dynamics and functional diversification in woody angiosperms remain underexplored. …”
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Vibrotactile Feedback Strategies for Trunk-Stabilizing Exercises in a Home-Based Scenario: Qualitative Interview Study Among Physiotherapists by Kaya Holzmeyer, Lisa-Marie Lüneburg, Luca Oppici, Philipp Flößel, Doris Lachmann, Jens Krzywinski, Susanne Narciss

“…For each exercise-specific motion pattern, it was recorded whether feedback was provided. …”
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Estimates on Age, Growth, Sex Composition, and Mortality of <i>Silurus lanzhouensis</i> (Chen, 1977) in the Upper Yellow River, China by Peilun Li, Jiacheng Liu, Shuhan Xiong, Tai Wang, Yongjie Wang, Jilong Wang

“…Further analysis of the length–weight relationships unveiled an allometric growth index (<i>b</i>) of 2.9562 for the overall samples, indicating an isometric growth pattern. Additionally, insights into the growth characteristics of <i>S. lanzhouensis</i> were provided by the von Bertalanffy growth function, revealing an asymptotic total length (<i>L_∞</i>) of 119.30 cm and a growth coefficient (<i>K</i>) of 0.1278 yr⁻¹. …”
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A novel stemness-related lncRNA signature predicts prognosis, immune infiltration and drug sensitivity of clear cell renal cell carcinoma by Jia Liu, Lin Yao, Yong Yang, Jinchao Ma, Ruijian You, Ziyi Yu, Peng Du

“…Abstract Background Clear cell renal cell carcinoma (ccRCC) is a prevalent urogenital malignancy characterized by heterogeneous patterns. Stemness is a pivotal factor in tumor progression, recurrence, and metastasis. …”
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Comprehensive analysis of scRNA-seq and bulk RNA-seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathy by Siyu He, Chunyu Li, Mingxin Lu, Fang Lin, Sangyu Hu, Junfang Zhang, Luying Peng, Li Li

“…Further analysis revealed high heterogeneity in tissue preference, gene expression, functional enrichment, immunodynamics, transcriptional regulatory factors, metabolic changes, and communication patterns in fibroblasts and myeloid cells. …”
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Understanding the influence of precipitation and nitrogen depositions on the soil health and growth indices of invasive (Solidago canadensis L.) and native (Wedelia chinesis) assoc... by Ismail Khan, Muhammad Tariq, Faisal Nadeem, Muhammad Sadiq Khan, Sulaiman Ali Alharbi, Saleh Alfarraj, Sezai Ercisli, Ayse Usanmaz Bozhuyuk, Ping Zhuang

“…These factors have important implications for ecosystem functioning and biodiversity in the face of climate change. …”
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CD79A and GADD45A as novel immune-related biomarkers for respiratory syncytial virus severity in children: an integrated machine learning analysis and clinical validation by Juan Juan Chen, Zhang Ze Lu, Yu Xin Jing, Xing Mei Nong, Yi Qin, Jin Yang Huang, Na Lin, Jie Wei

“…Immune cell profiling highlighted distinct infiltration patterns, with severe cases showing elevated naïve B cells and M0 macrophages versus activated NK cells and M1 macrophages in mild cases. …”
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