STAT1β modulates the tumor immune microenvironment to improve prognosis in ovarian cancer: a comprehensive study of transcriptional and protein expression differences by Ning Lan, Xintong Li, Yifan Qiao, Siyi Zhang, Min Chen, Xiaofeng Yang, Yuliang Zou, Juan Ren, Meili Pei

“…Abstract Objectives As a central regulator of the JAK/STAT signaling pathway, STAT1 generates functionally distinct α and β protein isoforms through alternative splicing. …”
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Sustainable Placemaking and Thermal Comfort Conditions in Urban Spaces: The Case Study of Avenida dos Aliados and Praça da Liberdade (Porto, Portugal) by Hélder Silva Lopes, Paula C. Remoaldo, Diogo Guedes Vidal, Vítor Ribeiro, Lígia Torres Silva, Javier Martín-Vide

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Single-cell RNA sequencing reveals the heterogeneity and regulatory modules of cell-specific RNA-binding proteins in patients with systemic lupus erythematosus by Sheng-Yan Lin, Yikai Yu, Daan Nie, Lili Yang, Yuxue Chen, Yu Chen, Cheng Wen, Zhipeng Zeng

“…Cell-type-specific RBPs expression patterns were systematically profiled across epidermal keratinocytes, dermal endothelial cells, and T cells. …”
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Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets by Hongye Liu, Yang Li, Ling Ren, Xiaofeng Yang, Shuo Zhang, Hongmei Bi, Hongxia He, Jingyu Ren, Xiaoqing Lang, Shuping Guo

“…ObjectiveThis study aims to identify potential target genes and therapeutic drugs for alopecia areata (AA).MethodsUtilizing training and testing data, we evaluated multi-gene panels derived from commonly upregulated genes in publicly available AA patient datasets. The functions of these genes in biological processes were analyzed to identify special multi-gene panels that may play crucial roles in AA. …”
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Genome-wide identification and characterization of the CCT gene family in Chinese cabbage (Brassica rapa) response to abiotic stress by Haoqi Liu, Zhiyuan Yin, Mengping Qiu, Yan Yang, Ye Xu, Han Wang, Min Yan, Guohua Xu

“…Results In this study, we conducted a genome-wide identification and analysis ofCCT genes in Chinese cabbage. …”
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How topographic factors regulate vegetation vigor in reservoir drawdown zones with different levels of hydrological disturbances? by Xu Zhou, Zhaofei Wen, Shengjun Wu

“…Topography plays a fundamental role in shaping vegetation distribution, community structure, and ecosystem functioning. This influence remains significant in hydrologically complex environments, particularly in reservoir drawdown zones (RDZs). …”
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Pelagic fish camouflage in shallow waters from the humboldt current system through intracellular structures and reflectance mechanisms by Caroline S. Montes, Ricardo F. Soto, Mario I. Sanhueza, Ignacio Sanhueza, Danny Luarte, Sebastián E. Godoy, Sergio N. Torres, Rosario Castillo, Rubén Escribano, Mauricio A. Urbina

“…These Scanning Electron Microscopy (SEM) images were analyzed using the 2D discrete Fourier transform to extract the spatial patterns that govern the light interaction with the guanine crystal structures. …”
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Genome-wide identification and expression profile analysis of TALE superfamily genes under hormone and abiotic stress in maize (Zea may L.) by Peiyan Guan, Dongbo Zhao, Longxue Wei, Peipei Cui, Shicai Zhang

“…These results can lay the foundation for analysis of the functions of ZmTALE genes under ABA and abiotic stresses.…”
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Strength-agility and fine motor are differently associated with non-verbal intelligence in dependency to sex and age in school children: Structural equation modelling multigroup ap... by Martin Musálek, Chipo Malambo, Jan Chrudimský, Jakub Kokštejn, Radka Bačáková, Šárka Vokounová

“…While motor proficiency has been positively linked to various cognitive functions in children, its relationship with nonverbal Intelligence remains an open question. …”
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Genome-wide identification, expression analysis, and response to abiotic stress of the phosphate transporter gene family in cucumber (Cucumis sativus L.) by Kunhao Xie, Mintao Sun, Xiaoqin Wang, Xiaoya Zhou, Qinghua Di, Yang Li, Guoxiu Wu, Yansu Li, Chaoxing He, Shengli Li

“…Conclusion This study conducted a systematic analysis of the CsPHT gene family, which provides a theoretical foundation and candidate genes for subsequent functional characterization and the genetic improvement of abiotic stress tolerance in cucumber.…”
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Integrated genomic and transcriptomic analysis of polydactyly in chickens by Zhiying Huang, Xiaomeng Miao, Diyan Li, Jia Liu, Haolin Chen, Yuan Su, Yuan Su

“…These findings offer clear targets for functional validation and may guide selective breeding for limb traits in poultry.…”
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Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study by Ikram Khan, Imran Khan, Ping Xie, Yu Xiaohui, Shengnan Lei, Tianzhu Song, Zhiqiang Li, Xiaodong Xie

“…Differential analyses were conducted to find key differential microbiota for MI. …”
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Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic... by Wenyang Nie, Wangzheqi Zhang, Zhikai Xiahou, Yuxuan Meng, Yuhang Liu, Jingwen Zhang, Zhen Wang, Yong Wang

“…Prognostic modeling was conducted using Cox regression and LASSO. Immune infiltration and drug sensitivity were evaluated by CIBERSORT, ESTIMATE, xCell, TIDE, and pRRophetic. …”
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Patient experience in retinitis pigmentosa and Choroideremia– a concept elicitation study in 17 patients based on qualitative interviews by Elke Rometsch, Per-Olof Thuresson, Noémie Hurst, Eckhart Eule, Isabel Bachmeier, Benoit Blanchard, José-Alain Sahel, Isabelle Audo

“…Despite different underlying genetic pathways, they have many progression patterns in common, first affecting the more peripheral retina and later advancing toward the central retina. …”
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Clinical characteristics of obsessive-compulsive disorder comorbid with obsessive -compulsive personality disorder: subtype implications by Ayse Dondu, Levent Sevincok

“…Diagnostic assessments were conducted according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). …”
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Critical energy distribution and fracture characteristics of heterogeneous rock under splitting condition by Hongguang JI, Zhen FU, Yuezheng ZHANG, Chunrui ZHANG, Dongsheng CHEN

“…The energy probability density functions of the entire process and the local stress stages follow power-law distributions, and as the deformation coordination deteriorates, the power-law distribution curve in the local stress stage at the later stage of loading gradually approaches the power-law curve of the entire process; ④ The change patterns of RA - AF values are similar for samples with different deformation coordination, but the samples with poorer deformation coordination have lower tensile strength, larger deformation space variability, more small-scale tensile fractures, rougher fracture surfaces with larger JRC, smaller released energy, and are more likely to enter a critical state, while the opposite is true for rocks with better deformation coordination. …”
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Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization by Yingquan Zhuo, Xiaoyun Feng, Wenqi Zhang, Jun Du, Xu Sun, Xi Luo, Wei Wang, Hua Jiang, Huajian Gu

“…In vitro and in vivo experiments were performed to investigate the biological functions of CTHRC1 in WT and its effects on M2-TAMs polarization. …”
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Exploring Work Engagement and Cynicism in Industry: A Preliminary Investigation in a Central Italian Engineering Company by Luca Di Giampaolo, Teresa Galanti, Michela Cortini, Simone De Sio, Claudia Giurgola, Federica Marino, Piergiorgio Astolfi, Rossella Martelli, Daria Ziccardi, Paola Borrelli, Laura Forcella, Maria Elisa Maiolo, Luca Coppeta

“…The results emphasize the need to expand the sample and to conduct comparative analyses across different teams within the company better understand engagement patterns and inform targeted interventions. …”
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Constitutive model of metal rubber material considering plastic accumulation behavior by FENG Zhipeng, YANG Fang, FU Hailong, AI Shigang, WANG Yue, YUAN Liangyang

“…Due to the complex and varied interlocking patterns of internal metallic helical coils during cold compression molding, residual stresses typically exist after forming. …”
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Improving Parameter Estimation of Fuel Cell Using Honey Badger Optimization Algorithm by Rolla Almodfer, Mohammed Mudhsh, Samah Alshathri, Laith Abualigah, Laith Abualigah, Mohamed Abd Elaziz, Mohamed Abd Elaziz, Mohamed Abd Elaziz, Khurram Shahzad, Mohamed Issa

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