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1441
A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer
Published 2025-02-01“…Immune “hot” tumor-related genes were identified, and their functional roles were validated through biological behavior analysis. …”
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1442
Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patients
Published 2025-08-01“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technologyResultsThirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1443
Retinol and Hydroxyasiaticoside Synergistically Relieve Histamine-Induced Atopic Dermatitis Activity by Repressing TRPV1, L1R1, and CD130 Targets
Published 2024-11-01“…<b>Background:</b> Retinol, an important bioactive substance with multiple physiological functions such as promoting collagen synthesis, inhibiting matrix metalloproteinase activity, alleviating oxidative stress, regulating gene expression, and promoting epidermal cell proliferation, has a significant effect on skin damage recovery. …”
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1444
ENHANCEMENT OF SENSOR PANEL TACTILE TOUCH INTERFACE
Published 2025-03-01“…The neural network is designed to learn the patterns and characteristics of the signals, allowing it to accurately classify new, unseen signals. …”
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1445
Exploring potential methylation markers for ovarian cancer from cervical scraping samples
Published 2025-05-01“…Furthermore, an over-representation analysis was conducted to explore the functions associated with genes mapped from differentially methylated positions (DMPs) in comparisons between normal and tumor samples, as well as between benign and malignant samples. …”
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1446
Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach
Published 2025-05-01“…Molecular docking simulations were conducted to assess the binding affinities between PFAS compounds and selected target proteins. …”
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1447
A usability evaluation framework for a mobile application in supporting home-based rehabilitation for stroke patients: A qualitative study
Published 2025-05-01“…Conclusions Satisfaction and performance surveys and qualitative data analysis revealed that most participants described the interface design of the app as intuitive and easy to use. Although some functions presented challenges, there was still a high level of satisfaction among both groups. …”
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1448
Genome-wide identification of PP2A gene family in Camellia sinensis reveals the potential role of CsPP2A-TON2/FASS1 in abiotic stress
Published 2025-05-01“…Further, a systematic study was conducted wherein physicochemical properties, phylogeny, gene structure and gene expression were explored. …”
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1449
Study on Enzyme Activity and Metabolomics during Culture of Liquid Spawn of <i>Floccularia luteovirens</i>
Published 2024-08-01“…An untargeted metabolomic analysis revealed that 3569 metabolites were detected in the <i>F. luteovirens</i> mycelium, including a variety of secondary metabolites and functional components, with terpenoids being particularly abundant, accounting for 148 types. …”
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1450
Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia
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1451
Simulation of the Extraction Efficiency of Coalbed Methane under Water Injection: A Gas-Liquid-Solid Coupling Model
Published 2020-01-01“…In this study, a series of experiments were conducted to study the differences in mechanical property changes under wetting conditions with different coal samples. …”
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1452
Compound Action Potential of Isolated Spinal Cord: A Biophysical Analysis to Address Activity of Individual Fibers Following Contusion Injury
Published 2013-06-01“…The current approach can be applied in the identification and evaluation of spinal cord function for experimental and clinical purposes.…”
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1453
The Kinematic Signature of the Warp and Waves in the Milky Way Disk
Published 2025-01-01“…Using over 170,000 red clump (RC) stars selected from LAMOST and APOGEE, we conduct a detailed analysis of the stellar V _Z as a function of L _Z (or R _g ) across different ϕ bins for various disk populations. …”
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1454
Comprehensive identification and expression analysis of the CPP gene family in maize (Zea mays L.)
Published 2025-05-01“…However, few reports have been reported on the function of ZmCPPs. This study conducted bioinformatics and expression analyses of the ZmCPP gene family. …”
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1455
Revealing the Immune Response of <i>Sitona callosus</i> Gyllenhal to Entomopathogenic Fungi <i>Beauveria bassiana</i> Infection Through Integrative Analyses of Transcriptomics and...
Published 2024-11-01“…Transcriptomic and metabolomic analyses were conducted to explore alterations in gene expression and metabolic processes in <i>S. callosus</i> at 48, 96, and 144 h post infection with <i>B. bassiana</i>. …”
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1456
Unveiling novel susceptibility genes and drug targets for basal cell carcinoma by a cross-tissue transcriptome-wide association study
Published 2025-03-01“…The cross-tissue TWAS was conducted to discover the candidate genes for BCC. …”
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1457
DC-SIGN Receptor Level in Rheumatoid Arthritis Patients in Baghdad; Serological study
Published 2022-12-01“…DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. …”
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1458
Use and diagnostic value of liver enzyme tests in the emergency department and subsequent heart failure diagnosis: a retrospective cohort study
Published 2022-03-01“…Objectives To determine (1) if liver function tests (LFTs) are ordered in the emergency department (ED) in patients with suspected acute decompensated heart failure (ADHF) and (2) if the pattern of LFT abnormalities are meaningfully associated with a discharge diagnosis of ADHF among patients for whom these tests were ordered.Setting We conducted a single-centre retrospective cohort study of patients with suspected ADHF who were seen in an academic tertiary ED using electronic medical records.Participants All ED patients admitted with suspected ADHF from January 2017 to May 2018, defined as any patient who had a brain natriuretic peptide (BNP) ordered.Primary outcome The primary outcome was ADHF diagnosis at discharge.Results In 5323 ED patients with suspected ADHF, 60% (n=3184) had LFTs ordered; 34.6% were abnormal. …”
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1459
Experimental Study on Tunnel Failure Mechanism and the Effect of Combined Anti-Dislocation Measures Under Fault Dislocation
Published 2025-01-01“…Taking the tunnels crossing active faults in China’s Sichuan–Tibet Railway as the research background, experimental studies were conducted using a custom-developed split model box. …”
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1460
Impaired interhemispheric synchrony in patients with iridocyclitis and classification using machine learning: an fMRI study
Published 2024-12-01“…BackgroundThis study examined the interhemispheric integration function pattern in patients with iridocyclitis utilizing the voxel-mirrored homotopic connectivity (VMHC) technique. …”
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